Taesung Park

Taesung Park

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Taesung Park

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BALLI: Bartlett-adjusted likelihood-based linear model approach for identifying differentially expressed genes with RNA-seq data.

BMC Genomics 2019 Jul 2;20(1):540. Epub 2019 Jul 2.

Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, 08826, South Korea.

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http://dx.doi.org/10.1186/s12864-019-5851-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604381PMC
July 2019

Pathway analysis of rare variants for the clustered phenotypes by using hierarchical structured components analysis.

BMC Med Genomics 2019 Jul 11;12(Suppl 5):100. Epub 2019 Jul 11.

Department of Statistics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1186/s12920-019-0517-4DOI Listing
July 2019

Meta-Qtest: meta-analysis of quadratic test for rare variants.

BMC Med Genomics 2019 Jul 11;12(Suppl 5):102. Epub 2019 Jul 11.

Department of Statistics, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1186/s12920-019-0516-5DOI Listing
July 2019

Develop Nomogram to Predict Malignancy of Intraductal Papillary Mucinous Neoplasm.

Methods Mol Biol 2019 ;1882:23-32

Department of Statistics, Seoul National University, Seoul, South Korea.

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http://link.springer.com/10.1007/978-1-4939-8879-2_3
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http://dx.doi.org/10.1007/978-1-4939-8879-2_3DOI Listing
June 2019

Longitudinal analysis to better characterize Asthma-COPD overlap syndrome: Findings from an adult asthma cohort in Korea (COREA).

Clin Exp Allergy 2019 May 14;49(5):603-614. Epub 2019 Feb 14.

Division of Allergy and Clinical Immunology, Department of Internal Medicine, Asan Medical Center, Ulsan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/cea.13339DOI Listing
May 2019

Glycoprotein 96 polymorphisms are associated with the risk of systemic lupus erythematosus: A case-control study.

Int J Rheum Dis 2019 May 12;22(5):905-912. Epub 2019 Mar 12.

Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/1756-185X.13515DOI Listing
May 2019

Effect of Interaction between Early Menarche and Genetic Polymorphisms on Triglyceride.

Oxid Med Cell Longev 2019 25;2019:9148920. Epub 2019 Feb 25.

Interdisciplinary Program in Bioinformatics and Department of Statistics, Seoul National University, 1 Kwanak-Ro, Kwanak-gu, Seoul 151-747, Republic of Korea.

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http://dx.doi.org/10.1155/2019/9148920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410422PMC
April 2019

In this issue, there are 10 articles: two review articles, six original articles, one clinical genomics, and one application note.

Authors:
Taesung Park

Genomics Inform 2019 Mar 31;17(1):e1. Epub 2019 Mar 31.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2019.17.1.e1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459168PMC
March 2019

HisCoM-mimi: Software for Hierarchical Structural Component Analysis for miRNA-mRNA Integration Model for Binary Phenotypes.

Genomics Inform 2019 Mar 31;17(1):e10. Epub 2019 Mar 31.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2019.17.1.e10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6459173PMC
March 2019

Detecting differential DNA methylation from sequencing of bisulfite converted DNA of diverse species.

Brief Bioinform 2019 01;20(1):33-46

School of Biological Sciences, Georgia Institute of Technology.

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http://dx.doi.org/10.1093/bib/bbx077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357555PMC
January 2019

Unified Cox model based multifactor dimensionality reduction method for gene-gene interaction analysis of the survival phenotype.

BioData Min 2018 14;11:27. Epub 2018 Dec 14.

2Department of Statistics, Seoul National University, Shilim-dong, Kwanak-gu, Seoul, 151-742 South Korea.

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http://dx.doi.org/10.1186/s13040-018-0189-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295107PMC
December 2018

HisCoM-GGI: Hierarchical structural component analysis of gene-gene interactions.

J Bioinform Comput Biol 2018 12 30;16(6):1840026. Epub 2018 Oct 30.

‡ Department of Statistics, Seoul National University, 1 Gwanak-ro Gwanak-gu, Seoul 08826, Republic of Korea.

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http://dx.doi.org/10.1142/S0219720018400267DOI Listing
December 2018

Editor's Introduction to This Issue (G&I 16:4, 2018).

Authors:
Taesung Park

Genomics Inform 2018 Dec 28;16(4):e16. Epub 2018 Dec 28.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2018.16.4.e16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440673PMC
December 2018

Ovarian Cancer Prognostic Prediction Model Using RNA Sequencing Data.

Genomics Inform 2018 Dec 28;16(4):e32. Epub 2018 Dec 28.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2018.16.4.e32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440672PMC
December 2018

EFMDR-Fast: An Application of Empirical Fuzzy Multifactor Dimensionality Reduction for Fast Execution.

Genomics Inform 2018 Dec 28;16(4):e37. Epub 2018 Dec 28.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2018.16.4.e37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440656PMC
December 2018

HisCoM-GGI: Software for Hierarchical Structural Component Analysis of Gene-Gene Interactions.

Genomics Inform 2018 Dec 28;16(4):e38. Epub 2018 Dec 28.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2018.16.4.e38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440671PMC
December 2018

Integration of a Large-Scale Genetic Analysis Workbench Increases the Accessibility of a High-Performance Pathway-Based Analysis Method.

Genomics Inform 2018 Dec 28;16(4):e39. Epub 2018 Dec 28.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2018.16.4.e39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440666PMC
December 2018

Development of Web-Based Nomograms to Predict Treatment Response and Prognosis of Epithelial Ovarian Cancer.

Cancer Res Treat 2018 Nov 20. Epub 2018 Nov 20.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2018.508DOI Listing
November 2018

Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals.

PLoS Comput Biol 2018 10 5;14(10):e1006451. Epub 2018 Oct 5.

School of Biological Sciences, Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, United States of America.

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http://dx.plos.org/10.1371/journal.pcbi.1006451
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http://dx.doi.org/10.1371/journal.pcbi.1006451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192654PMC
October 2018

Drug response prediction model using a hierarchical structural component modeling method.

BMC Bioinformatics 2018 Aug 13;19(Suppl 9):288. Epub 2018 Aug 13.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, 08826, South Korea.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2270-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101092PMC
August 2018

Nuclear receptor and VEGF pathways for gene-blood lead interactions, on bone mineral density, in Korean smokers.

PLoS One 2018 8;13(3):e0193323. Epub 2018 Mar 8.

Interdisciplinary Program in Bioinformatics and Department of Statistics, Seoul National University, Gwanak 1 Gwanak-ro, Gwanak-gu, Seoul, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193323PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843219PMC
June 2018

Hierarchical structural component modeling of microRNA-mRNA integration analysis.

BMC Bioinformatics 2018 05 8;19(Suppl 4):75. Epub 2018 May 8.

Department of Statistics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1186/s12859-018-2070-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998903PMC
May 2018

Pathway-based approach using hierarchical components of rare variants to analyze multiple phenotypes.

BMC Bioinformatics 2018 05 8;19(Suppl 4):79. Epub 2018 May 8.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1186/s12859-018-2066-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998880PMC
May 2018

New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

Sci Rep 2018 Apr 9;8(1):5701. Epub 2018 Apr 9.

Department of Statistics, Seoul National University, Seoul, 08826, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-018-23074-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5890262PMC
April 2018

WISARD: workbench for integrated superfast association studies for related datasets.

BMC Med Genomics 2018 04 20;11(Suppl 2):39. Epub 2018 Apr 20.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1186/s12920-018-0345-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918457PMC
April 2018

Fuzzy set-based generalized multifactor dimensionality reduction analysis of gene-gene interactions.

BMC Med Genomics 2018 04 20;11(Suppl 2):32. Epub 2018 Apr 20.

Department of Statistics, Seoul National University, Seoul, 08826, South Korea.

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http://dx.doi.org/10.1186/s12920-018-0343-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918459PMC
April 2018

Exact association test for small size sequencing data.

BMC Med Genomics 2018 04 20;11(Suppl 2):30. Epub 2018 Apr 20.

Department of Statistics, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1186/s12920-018-0344-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918458PMC
April 2018

Effects of genetic variants of ST8SIA2 and NCAM1 genes on seasonal mood changes and circadian preference in the general population.

Chronobiol Int 2018 03 7;35(3):405-415. Epub 2017 Dec 7.

a Department of Psychiatry , Sungkyunkwan University School of Medicine, Samsung Medical Center , Seoul , Korea.

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https://www.tandfonline.com/doi/full/10.1080/07420528.2017.1
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http://dx.doi.org/10.1080/07420528.2017.1410827DOI Listing
March 2018

GxGrare: gene-gene interaction analysis method for rare variants from high-throughput sequencing data.

BMC Syst Biol 2018 03 19;12(Suppl 2):19. Epub 2018 Mar 19.

Department of Statistics, Seoul National University, Seoul, 08826, South Korea.

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http://dx.doi.org/10.1186/s12918-018-0543-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861485PMC
March 2018

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.

Proc Natl Acad Sci U S A 2018 01 26;115(2):379-384. Epub 2017 Dec 26.

South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville and Edinburg, TX 78520.

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http://dx.doi.org/10.1073/pnas.1705859115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777025PMC
January 2018

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2018 01 23;5:180002. Epub 2018 Jan 23.

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http://dx.doi.org/10.1038/sdata.2018.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779067PMC
January 2018

Prognostic significance of E-cadherin and ZEB1 expression in intraductal papillary mucinous neoplasm.

Oncotarget 2018 Jan 7;9(1):306-320. Epub 2017 Dec 7.

Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://www.oncotarget.com/fulltext/23012
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http://dx.doi.org/10.18632/oncotarget.23012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787467PMC
January 2018

CONCORD biomarker prediction for novel drug introduction to different cancer types.

Oncotarget 2018 Jan 9;9(1):1091-1106. Epub 2017 Dec 9.

Department of Biostatistics and Bioinformatics, Moffitt Cancer Center, Tampa, FL, USA.

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http://www.oncotarget.com/fulltext/23124
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http://dx.doi.org/10.18632/oncotarget.23124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5787421PMC
January 2018

Proposed Nomogram Predicting the Individual Risk of Malignancy in the Patients With Branch Duct Type Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Ann Surg 2017 12;266(6):1062-1068

*Department of Surgery, Seoul National University College of Medicine, Seoul, Korea †Department of Statistics, Seoul National University College of Natural Sciences, Seoul, Korea ‡Department of Mathematics and Statistics, Sejong University College of Natural Sciences, Seoul, Korea §Department of Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea ¶Department of Surgery, Tokyo Women's Medical University, Institute of Gastroenterology, Tokyo, Japan ||Department of Surgery, International University of Health and Welfare Mita Hospital, Surgery, Tokyo Women's Medical University, Institute of Gastroenterology, Tokyo, Japan **Second Department of Surgery, School of Medicine, Wakayama Medical University, Wakayama, Japan ††Department of Surgery, Kansai Medical University, Moriguchi, Osaka, Japan ‡‡Department of Surgery, Nagoya University, Nagoya, Japan §§Department of Surgery, Hokkaido University, Hokkaido, Japan ¶¶Department of Surgery, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan ||||Gastroenterological Surgery, Aichi Cancer Center Hospital, Aichi, Japan ***Department of Surgery, Sungkyunkwan University School of Medicine, Seoul, Korea †††Department of Surgery, Tohoku University, Tohoku, Japan ‡‡‡Department of Surgery, Kobe University Graduate School of Medicine, Kobe, Japan §§§Pancreaticobiliary Cancer Clinic, Yonsei University College of Medicine, Yonsei Cancer Center, Severance Hospital, Surgery, Seoul, Korea ¶¶¶Department of Surgery, Seoul National University Bundang Hospital, Surgery, Seoul National University College of Medicine, Seoul, Korea ||||||Department of Surgery, Seoul National University College of Medicine, Surgery, Seoul National University Bundang Hospital, Seoul, Korea ****Department of Surgery, Nara Medical University, Nara, Japan ††††Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Japan ‡‡‡‡Department of Surgery, Tokyo Metropolitan Cancer and Infectious diseases Center Komagome Hospital, Tokyo, Japan §§§§Department of Surgery, Kyungpook National University, Daegu, Korea ¶¶¶¶Department of Surgery, Chonbuk National University, Jeonju, Korea ||||||||Department of Surgery, Soonchunhyang University, Asan, Korea *****Department of Surgery, Tokyo Medical University, Tokyo, Japan †††††Department of Surgery, Pusan National University, Pusan, Korea.

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http://Insights.ovid.com/crossref?an=00000658-201712000-0002
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http://dx.doi.org/10.1097/SLA.0000000000001985DOI Listing
December 2017

Long-term response to mood stabilizer treatment and its clinical correlates in patients with bipolar disorders: a retrospective observational study.

Int J Bipolar Disord 2017 Dec 9;5(1):24. Epub 2017 Jul 9.

Department of Psychiatry, Sunkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.

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http://dx.doi.org/10.1186/s40345-017-0093-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502006PMC
December 2017

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana Cn Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2017 12 19;4:170179. Epub 2017 Dec 19.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/sdata.2017.179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735917PMC
December 2017

Analysis of population-specific pharmacogenomic variants using next-generation sequencing data.

Sci Rep 2017 09 4;7(1):8416. Epub 2017 Sep 4.

Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, 151-747, Korea.

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http://dx.doi.org/10.1038/s41598-017-08468-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583360PMC
September 2017

CANcer-specific Evaluation System (CANES): a high-accuracy platform, for preclinical single/multi-biomarker discovery.

Oncotarget 2017 Sep 15;8(41):69808-69822. Epub 2017 Jul 15.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.18632/oncotarget.19270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642518PMC
September 2017

LPEseq: Local-Pooled-Error Test for RNA Sequencing Experiments with a Small Number of Replicates.

PLoS One 2016 17;11(8):e0159182. Epub 2016 Aug 17.

Department of Statistics, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159182PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988759PMC
August 2017

Proposed new staging system for ampulla of Vater cancer with greater discriminatory ability: multinational study from eastern and western centers.

J Hepatobiliary Pancreat Sci 2017 Aug 4;24(8):475-484. Epub 2017 Aug 4.

Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1002/jhbp.486DOI Listing
August 2017

Efficient Statistical Method for Association Analysis of X-Linked Variants.

Hum Hered 2016 16;82(1-2):50-63. Epub 2017 Aug 16.

Department of Public Health Science, Graduate School of Public Health, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1159/000478048DOI Listing
August 2017

Serum fibronectin distinguishes the early stages of hepatocellular carcinoma.

Sci Rep 2017 08 25;7(1):9449. Epub 2017 Aug 25.

Department of Biomedical Sciences, Seoul National University College of Medicine, Yongon-Dong, Seoul, 110-799, Korea.

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http://dx.doi.org/10.1038/s41598-017-09691-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573357PMC
August 2017

Derivation and validation of a risk scoring model to predict advanced colorectal neoplasm in adults of all ages.

J Gastroenterol Hepatol 2017 Jul;32(7):1328-1335

Division of Gastroenterology, Department of Internal Medicine and Gastrointestinal Cancer Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/jgh.13711DOI Listing
July 2017

A Low-Frequency Inactivating Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

Authors:
Alisa Manning Heather M Highland Jessica Gasser Xueling Sim Taru Tukiainen Pierre Fontanillas Niels Grarup Manuel A Rivas Anubha Mahajan Adam E Locke Pablo Cingolani Tune H Pers Ana Viñuela Andrew A Brown Ying Wu Jason Flannick Christian Fuchsberger Eric R Gamazon Kyle J Gaulton Hae Kyung Im Tanya M Teslovich Thomas W Blackwell Jette Bork-Jensen Noël P Burtt Yuhui Chen Todd Green Christopher Hartl Hyun Min Kang Ashish Kumar Claes Ladenvall Clement Ma Loukas Moutsianas Richard D Pearson John R B Perry N William Rayner Neil R Robertson Laura J Scott Martijn van de Bunt Johan G Eriksson Antti Jula Seppo Koskinen Terho Lehtimäki Aarno Palotie Olli T Raitakari Suzanne B R Jacobs Jennifer Wessel Audrey Y Chu Robert A Scott Mark O Goodarzi Christine Blancher Gemma Buck David Buck Peter S Chines Stacey Gabriel Anette P Gjesing Christopher J Groves Mette Hollensted Jeroen R Huyghe Anne U Jackson Goo Jun Johanne Marie Justesen Massimo Mangino Jacquelyn Murphy Matt Neville Robert Onofrio Kerrin S Small Heather M Stringham Joseph Trakalo Eric Banks Jason Carey Mauricio O Carneiro Mark DePristo Yossi Farjoun Timothy Fennell Jacqueline I Goldstein George Grant Martin Hrabé de Angelis Jared Maguire Benjamin M Neale Ryan Poplin Shaun Purcell Thomas Schwarzmayr Khalid Shakir Joshua D Smith Tim M Strom Thomas Wieland Jaana Lindstrom Ivan Brandslund Cramer Christensen Gabriela L Surdulescu Timo A Lakka Alex S F Doney Peter Nilsson Nicholas J Wareham Claudia Langenberg Tibor V Varga Paul W Franks Olov Rolandsson Anders H Rosengren Vidya S Farook Farook Thameem Sobha Puppala Satish Kumar Donna M Lehman Christopher P Jenkinson Joanne E Curran Daniel Esten Hale Sharon P Fowler Rector Arya Ralph A DeFronzo Hanna E Abboud Ann-Christine Syvänen Pamela J Hicks Nicholette D Palmer Maggie C Y Ng Donald W Bowden Barry I Freedman Tõnu Esko Reedik Mägi Lili Milani Evelin Mihailov Andres Metspalu Narisu Narisu Leena Kinnunen Lori L Bonnycastle Amy Swift Dorota Pasko Andrew R Wood João Fadista Toni I Pollin Nir Barzilai Gil Atzmon Benjamin Glaser Barbara Thorand Konstantin Strauch Annette Peters Michael Roden Martina Müller-Nurasyid Liming Liang Jennifer Kriebel Thomas Illig Harald Grallert Christian Gieger Christa Meisinger Lars Lannfelt Solomon K Musani Michael Griswold Herman A Taylor Gregory Wilson Adolfo Correa Heikki Oksa William R Scott Uzma Afzal Sian-Tsung Tan Marie Loh John C Chambers Jobanpreet Sehmi Jaspal Singh Kooner Benjamin Lehne Yoon Shin Cho Jong-Young Lee Bok-Ghee Han Annemari Käräjämäki Qibin Qi Lu Qi Jinyan Huang Frank B Hu Olle Melander Marju Orho-Melander Jennifer E Below David Aguilar Tien Yin Wong Jianjun Liu Chiea-Chuen Khor Kee Seng Chia Wei Yen Lim Ching-Yu Cheng Edmund Chan E Shyong Tai Tin Aung Allan Linneberg Bo Isomaa Thomas Meitinger Tiinamaija Tuomi Liisa Hakaste Jasmina Kravic Marit E Jørgensen Torsten Lauritzen Panos Deloukas Kathleen E Stirrups Katharine R Owen Andrew J Farmer Timothy M Frayling Stephen P O'Rahilly Mark Walker Jonathan C Levy Dylan Hodgkiss Andrew T Hattersley Teemu Kuulasmaa Alena Stančáková Inês Barroso Dwaipayan Bharadwaj Juliana Chan Giriraj R Chandak Mark J Daly Peter J Donnelly Shah B Ebrahim Paul Elliott Tasha Fingerlin Philippe Froguel Cheng Hu Weiping Jia Ronald C W Ma Gilean McVean Taesung Park Dorairaj Prabhakaran Manjinder Sandhu James Scott Rob Sladek Nikhil Tandon Yik Ying Teo Eleftheria Zeggini Richard M Watanabe Heikki A Koistinen Y Antero Kesaniemi Matti Uusitupa Timothy D Spector Veikko Salomaa Rainer Rauramaa Colin N A Palmer Inga Prokopenko Andrew D Morris Richard N Bergman Francis S Collins Lars Lind Erik Ingelsson Jaakko Tuomilehto Fredrik Karpe Leif Groop Torben Jørgensen Torben Hansen Oluf Pedersen Johanna Kuusisto Gonçalo Abecasis Graeme I Bell John Blangero Nancy J Cox Ravindranath Duggirala Mark Seielstad James G Wilson Josee Dupuis Samuli Ripatti Craig L Hanis Jose C Florez Karen L Mohlke James B Meigs Markku Laakso Andrew P Morris Michael Boehnke David Altshuler Mark I McCarthy Anna L Gloyn Cecilia M Lindgren

Diabetes 2017 07 24;66(7):2019-2032. Epub 2017 Mar 24.

Program in Medical and Population Genetics, Broad Institute, Cambridge, MA.

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http://dx.doi.org/10.2337/db16-1329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482074PMC
July 2017

Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries.

Bipolar Disord 2017 06 22;19(4):305-313. Epub 2017 May 22.

Department of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea.

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http://dx.doi.org/10.1111/bdi.12493DOI Listing
June 2017

Correlation estimation with singly truncated bivariate data.

Stat Med 2017 05 27;36(12):1977-1988. Epub 2017 Feb 27.

Department of Statistics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/sim.7267DOI Listing
May 2017

Rare variant association test with multiple phenotypes.

Genet Epidemiol 2017 04 31;41(3):198-209. Epub 2016 Dec 31.

Department of Statistics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/gepi.22021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340648PMC
April 2017

Ceruloplasmin as a prognostic marker in patients with bile duct cancer.

Oncotarget 2017 Apr;8(17):29028-29037

Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Chongno-Gu, Seoul 110-744, Korea.

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http://dx.doi.org/10.18632/oncotarget.15995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438709PMC
April 2017

Targeted Proteomics Predicts a Sustained Complete-Response after Transarterial Chemoembolization and Clinical Outcomes in Patients with Hepatocellular Carcinoma: A Prospective Cohort Study.

J Proteome Res 2017 03 30;16(3):1239-1248. Epub 2017 Jan 30.

Department of Internal Medicine and Liver Research Institute, ‡Department of Biomedical Engineering, and §Institute of Medical and Biological Engineering, Medical Research Center, Seoul National University College of Medicine , Yongon-Dong, Seoul 110-799, Korea.

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http://dx.doi.org/10.1021/acs.jproteome.6b00833DOI Listing
March 2017

Pathway-Driven Approaches of Interaction between Oxidative Balance and Genetic Polymorphism on Metabolic Syndrome.

Oxid Med Cell Longev 2017 16;2017:6873197. Epub 2017 Jan 16.

Interdisciplinary Program in Bioinformatics and Department of Statistics, Seoul National University, Seoul 152-742, Republic of Korea.

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http://dx.doi.org/10.1155/2017/6873197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278231PMC
March 2017

An empirical fuzzy multifactor dimensionality reduction method for detecting gene-gene interactions.

BMC Genomics 2017 03 14;18(Suppl 2):115. Epub 2017 Mar 14.

Department of Statistics, Seoul National University, Seoul, 08826, South Korea.

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http://dx.doi.org/10.1186/s12864-017-3496-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5374597PMC
March 2017

Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice.

Neuropharmacology 2017 01 17;112(Pt A):104-112. Epub 2016 Aug 17.

Laboratory of Neurobiology, School of Biological Sciences, College of Natural Sciences, Seoul National University, Seoul, 08826, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2016.08.016DOI Listing
January 2017

PreCimp: Pre-collapsing imputation approach increases imputation accuracy of rare variants in terms of collapsed variables.

Genet Epidemiol 2017 Jan 10;41(1):41-50. Epub 2016 Nov 10.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/gepi.22020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154802PMC
January 2017

Dietary Wolfberry Extract Modifies Oxidative Stress by Controlling the Expression of Inflammatory mRNAs in Overweight and Hypercholesterolemic Subjects: A Randomized, Double-Blind, Placebo-Controlled Trial.

J Agric Food Chem 2017 Jan 9;65(2):309-316. Epub 2017 Jan 9.

Department of Food Science and Technology, Seoul National University of Science and Technology , Seoul 139-743, Republic of Korea.

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http://dx.doi.org/10.1021/acs.jafc.6b04701DOI Listing
January 2017

A novel fuzzy set based multifactor dimensionality reduction method for detecting gene-gene interaction.

Comput Biol Chem 2016 12 29;65:193-202. Epub 2016 Sep 29.

Department of Statistics, Seoul National University, Seoul, 08826, South Korea; Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, 08826, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.compbiolchem.2016.09.006DOI Listing
December 2016

Editor's Introduction to This Issue.

Authors:
Taesung Park

Genomics Inform 2016 Dec 30;14(4):137. Epub 2016 Dec 30.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2016.14.4.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287116PMC
December 2016

Risk Prediction Using Genome-Wide Association Studies on Type 2 Diabetes.

Genomics Inform 2016 Dec 30;14(4):138-148. Epub 2016 Dec 30.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.; Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2016.14.4.138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287117PMC
December 2016

Prediction of Quantitative Traits Using Common Genetic Variants: Application to Body Mass Index.

Genomics Inform 2016 Dec 30;14(4):149-159. Epub 2016 Dec 30.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 08826, Korea.; Bioinformatics and Biostatistics Lab, Seoul National University, Seoul 08826, Korea.; Department of Statistics, Seoul National University, Seoul 08826, Korea.

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Publisher Site
http://dx.doi.org/10.5808/GI.2016.14.4.149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287118PMC
December 2016

Gene-Gene Interaction Analysis for the Accelerated Failure Time Model Using a Unified Model-Based Multifactor Dimensionality Reduction Method.

Genomics Inform 2016 Dec 30;14(4):166-172. Epub 2016 Dec 30.

Department of Statistics, Seoul National University, Seoul 08826, Korea.

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http://dx.doi.org/10.5808/GI.2016.14.4.166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287120PMC
December 2016

Genetic Association Analysis of Fasting and 1- and 2-Hour Glucose Tolerance Test Data Using a Generalized Index of Dissimilarity Measure for the Korean Population.

Genomics Inform 2016 Dec 30;14(4):181-186. Epub 2016 Dec 30.

Department of Preventive Medicine, Eulji University, Daejeon 34824, Korea.

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http://dx.doi.org/10.5808/GI.2016.14.4.181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287122PMC
December 2016

Development of Diagnostic Biomarkers for Detecting Diabetic Retinopathy at Early Stages Using Quantitative Proteomics.

J Diabetes Res 2016 9;2016:6571976. Epub 2015 Nov 9.

Department of Biomedical Sciences, Seoul National University College of Medicine, 28 Yongon-Dong, Seoul 110-799, Republic of Korea ; Department of Biomedical Engineering, Seoul National University College of Medicine, 28 Yongon-Dong, Seoul 110-799, Republic of Korea.

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http://dx.doi.org/10.1155/2016/6571976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657408PMC
October 2016

Analysis of multiple related phenotypes in genome-wide association studies.

J Bioinform Comput Biol 2016 10 9;14(5):1644005. Epub 2016 Sep 9.

* Department of Statistics, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea.

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http://dx.doi.org/10.1142/S0219720016440054DOI Listing
October 2016

Conditional estimation of local pooled dispersion parameter in small-sample RNA-Seq data improves differential expression test.

J Bioinform Comput Biol 2016 10 15;14(5):1644006. Epub 2016 Sep 15.

‡ Department of Statistics, Seoul National University, Gwanak-gu Seoul, 151-747, South Korea.

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http://dx.doi.org/10.1142/S0219720016440066DOI Listing
October 2016

Comparing family-based rare variant association tests for dichotomous phenotypes.

BMC Proc 2016 18;10(Suppl 7):181-186. Epub 2016 Oct 18.

Interdisciplinary Program in bioinformatics, Seoul National University, Seoul, 151-742 Korea ; Department of Public Health Science, Seoul National University, Seoul, 151-742 Korea ; Institute of Health Environment, Seoul National University, Seoul, 151-742 Korea.

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http://dx.doi.org/10.1186/s12919-016-0027-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133528PMC
October 2016

FARVATX: Family-Based Rare Variant Association Test for X-Linked Genes.

Genet Epidemiol 2016 09 21;40(6):475-85. Epub 2016 Jun 21.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/gepi.21979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981534PMC
September 2016

Pathway-based approach using hierarchical components of collapsed rare variants.

Bioinformatics 2016 09;32(17):i586-i594

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul 151-747, Korea Department of Statistics, Seoul National University, Seoul 151-747, Korea.

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http://dx.doi.org/10.1093/bioinformatics/btw425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013912PMC
September 2016

A unified model based multifactor dimensionality reduction framework for detecting gene-gene interactions.

Bioinformatics 2016 09;32(17):i605-i610

Department of Statistics, Seoul National University, Shilim-Dong, Kwanak-Gu, Seoul 151-742, Korea.

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http://dx.doi.org/10.1093/bioinformatics/btw424DOI Listing
September 2016

Gene-set association tests for next-generation sequencing data.

Bioinformatics 2016 09;32(17):i611-i619

Department of Statistics, Seoul National University, Seoul 151-742, Korea.

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http://dx.doi.org/10.1093/bioinformatics/btw429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013913PMC
September 2016

The genetic architecture of type 2 diabetes.

Authors:
Christian Fuchsberger Jason Flannick Tanya M Teslovich Anubha Mahajan Vineeta Agarwala Kyle J Gaulton Clement Ma Pierre Fontanillas Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Denis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Yvonne T van der Schouw Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeriya Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Noël P Burtt Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Jose C Florez Laura J Scott Andrew P Morris Hyun Min Kang Michael Boehnke David Altshuler Mark I McCarthy

Nature 2016 08 11;536(7614):41-47. Epub 2016 Jul 11.

Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

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Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK, Department of Biostatistics, University of Liverpool, Liverpool, UK

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Predicting multi-class responses to preoperative chemoradiotherapy in rectal cancer patients.

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Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 135-710, Korea.

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Department of Biomedical Engineering, ‡Surgery and Cancer Research Institute, and §Department of Pathology, Seoul National University College of Medicine , 28 Yongon-Dong, Seoul 110-799 Korea.

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BMC Genomics 2015 Dec 29;16:1109. Epub 2015 Dec 29.

Interdisciplinary Program in Bioinformatics, Seoul National University, Seoul, 151-742, South Korea.

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