Dr. Taesun Eom, PhD - SUNY Downstate Medical Center - Research Assistant Professor

Dr. Taesun Eom

PhD

SUNY Downstate Medical Center

Research Assistant Professor

Brooklyn, NY | United States

Main Specialties: Neurology

Additional Specialties: Neuroscience

Dr. Taesun Eom, PhD - SUNY Downstate Medical Center - Research Assistant Professor

Dr. Taesun Eom

PhD

Introduction

Primary Affiliation: SUNY Downstate Medical Center - Brooklyn, NY , United States

Specialties:

Additional Specialties:

Publications

7Publications

50Reads

-Profile Views

289PubMed Central Citations

Neuronal BC RNAs cooperate with eIF4B to mediate activity-dependent translational control.

J Cell Biol 2014 Oct 20;207(2):237-52. Epub 2014 Oct 20.

Department of Physiology and Pharmacology, Department of Anesthesiology, and Department of Neurology, The Robert F. Furchgott Center for Neural and Behavioral Science, SUNY Downstate Medical Center, Brooklyn, NY 11203 Department of Physiology and Pharmacology, Department of Anesthesiology, and Department of Neurology, The Robert F. Furchgott Center for Neural and Behavioral Science, SUNY Downstate Medical Center, Brooklyn, NY 11203

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http://dx.doi.org/10.1083/jcb.201401005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210447PMC
October 2014
8 Reads
18 Citations
9.834 Impact Factor

NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure.

Elife 2013 Jan 22;2:e00178. Epub 2013 Jan 22.

Laboratory of Molecular Neuro-Oncology , Rockefeller University , New York , United States.

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http://dx.doi.org/10.7554/eLife.00178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552424PMC
January 2013
6 Reads
30 Citations
8.520 Impact Factor

Dual nature of translational control by regulatory BC RNAs.

Mol Cell Biol 2011 Nov 19;31(22):4538-49. Epub 2011 Sep 19.

The Robert F. Furchgott Center for Neural and Behavioral Science, Department of Physiology and Pharmacology, State University of New York, Health Science Center at Brooklyn, Brooklyn, New York 11203, USA.

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http://dx.doi.org/10.1128/MCB.05885-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209249PMC
November 2011
1 Read
15 Citations
4.780 Impact Factor

The Neuronal Splicing Factor Nova Co-Localizes with Target RNAs in the Dendrite.

Front Neural Circuits 2010 3;4. Epub 2010 Mar 3.

Biologie Cellulaire de la Synapse Normale et Pathologique, Institut National de la Santé et de la Recherche Médicale, Ecole Normale Supérieure Paris, France.

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http://dx.doi.org/10.3389/neuro.04.005.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856630PMC
July 2011
19 Reads
30 Citations
3.570 Impact Factor

Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls.

Science 2010 Jul 17;329(5990):439-43. Epub 2010 Jun 17.

Laboratory of Molecular Neuro-Oncology, Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

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http://dx.doi.org/10.1126/science.1191150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412410PMC
July 2010
8 Reads
128 Citations
31.480 Impact Factor

Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses.

J Neurosci 2003 Nov;23(32):10433-44

Department of Neuroscience, Rose F. Kennedy Center for Mental Retardation, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

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November 2003
8 Reads
68 Citations
6.344 Impact Factor

Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility.

Neuron. 2001 Aug 2;31(2):261-75.

neuron

Neurotrophin regulation of actin-dependent changes in growth cone motility may depend on the signaling of beta-actin mRNA transport. Formation of an RNP complex between the beta-actin mRNA zipcode sequence and Zipcode Binding Protein 1 (ZBP1) was required for its localization to growth cones. Antisense oligonucleotides to the zipcode inhibited formation of this RNP complex in vitro and the neurotrophin-induced localization of beta-actin mRNA and ZBP1 granules. Live cell imaging of neurons transfected with EGFP-ZBP1 revealed fast, bidirectional movements of granules in neurites that were inhibited by antisense treatment, as visualized by FRAP analysis. NT-3 stimulation of beta-actin protein localization was dependent on the 3'UTR and inhibited by antisense treatment. Growth cones exhibited impaired motility in the presense of antisense. These results suggest a novel mechanism to influence growth cone dynamics involving the regulated transport of mRNA

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August 2001
3 Reads