Taco W Kuijpers

Taco W Kuijpers

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Taco W Kuijpers

Publications by authors named "Taco W Kuijpers"

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T-mapping for assessing knee joint cartilage in children with juvenile idiopathic arthritis - feasibility and repeatability.

Pediatr Radiol 2019 Nov 9. Epub 2019 Nov 9.

Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centers, location AMC, Meibergdreef 9, Room G1-226, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00247-019-04557-4DOI Listing
November 2019

Loss of ARPC1B impairs cytotoxic T lymphocyte maintenance and cytolytic activity.

J Clin Invest 2019 Nov 11. Epub 2019 Nov 11.

Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1172/JCI129388DOI Listing
November 2019

Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming.

Cell Rep 2019 Nov;29(8):2505-2519.e4

Department of Blood Cell Research, Sanquin Research, Amsterdam University Medical Center (AUMC), University of Amsterdam, Amsterdam, the Netherlands; Department of Paediatric Immunology and Infectious Diseases, Emma Children's Hospital, AUMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.10.082DOI Listing
November 2019

Functional Attributes of Antibodies, Effector Cells, and Target Cells Affecting NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity.

J Immunol 2019 Nov 20. Epub 2019 Nov 20.

Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands;

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http://dx.doi.org/10.4049/jimmunol.1900985DOI Listing
November 2019

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Haematologica 2019 Oct 10;104(10):2091-2099. Epub 2019 Jan 10.

Molecular and Cellular Hemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.207787DOI Listing
October 2019

Tissue-specific expression of IgG receptors by human macrophages ex vivo.

PLoS One 2019 15;14(10):e0223264. Epub 2019 Oct 15.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223264PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793881PMC
October 2019

High-throughput compound screen reveals mTOR inhibitors as potential therapeutics to reduce (auto)antibody production by human plasma cells.

Eur J Immunol 2019 Oct 17. Epub 2019 Oct 17.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Department of Pediatric Immunology, Rheumatology and Infectious diseases, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.201948241DOI Listing
October 2019

Genetic Variation in Low-To-Medium-Affinity Fcγ Receptors: Functional Consequences, Disease Associations, and Opportunities for Personalized Medicine.

Front Immunol 2019 3;10:2237. Epub 2019 Oct 3.

Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.02237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786274PMC
October 2019

IgG Glyco-Engineering to Improve IVIg Potency.

Front Immunol 2018 23;9:2442. Epub 2018 Oct 23.

Sanquin Research and Landsteiner Laboratory, Department of Blood Cell Research, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02442
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http://dx.doi.org/10.3389/fimmu.2018.02442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6206079PMC
September 2019

Identification of genetic biomarkers for alloimmunization in sickle cell disease.

Br J Haematol 2019 Sep 5;186(6):887-899. Epub 2019 Jun 5.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/bjh.15998DOI Listing
September 2019

Neutrophils as Suppressors of T Cell Proliferation: Does Age Matter?

Front Immunol 2019 11;10:2144. Epub 2019 Sep 11.

Department of Blood Cell Research, Sanquin Research, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2019.02144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749034PMC
September 2019

Diagnostic Yield of Next Generation Sequencing in Genetically Undiagnosed Patients with Primary Immunodeficiencies: a Systematic Review.

J Clin Immunol 2019 Aug 28;39(6):577-591. Epub 2019 Jun 28.

Department of Pediatric Immunology and Infectious Diseases, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/s10875-019-00656-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697711PMC
August 2019

Complement Factor H-Related Protein 4A Is the Dominant Circulating Splice Variant of .

Front Immunol 2018 17;9:729. Epub 2018 Apr 17.

Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's hospital, Academic Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913293PMC
June 2019

High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele .

Front Immunol 2018 24;9:848. Epub 2018 Apr 24.

Complement Research Group, Hospital La Paz Institute for Health Research (IdiPAZ), La Paz University Hospital, Center for Biomedical Network Research on Rare Diseases (CIBERER), Madrid, Spain.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928496PMC
June 2019

A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency.

J Allergy Clin Immunol 2019 Jun 13;143(6):2296-2299. Epub 2019 Feb 13.

Department of Pediatric Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory AMC, University of Amsterdam, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677392PMC
June 2019

Pathogenic NFKB2 variant in the ankyrin repeat domain (R635X) causes a variable antibody deficiency.

Clin Immunol 2019 Jun 3;203:23-27. Epub 2019 Apr 3.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Department of Pediatric Immunology, Rheumatology and Infectious diseases, Meibergdreef 9, Amsterdam, The Netherlands; Amsterdam UMC, University of Amsterdam, Department of Experimental Immunology, Amsterdam Infection & Immunity Institute, Meibergdreef 9, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2019.03.010DOI Listing
June 2019

Neutrophils acquire antigen-presenting cell features after phagocytosis of IgG-opsonized erythrocytes.

Blood Adv 2019 Jun;3(11):1761-1773

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/bloodadvances.2018028753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6560339PMC
June 2019

Consider the wrist: a retrospective study on pediatric connective tissue disease with MRI.

Rheumatol Int 2019 Jun 20. Epub 2019 Jun 20.

Department of Pediatric Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital, Amsterdam University Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00296-019-04353-1DOI Listing
June 2019

Diagnostic Challenges in the Early Onset of Inflammatory Bowel Disease: A Case Report.

Int J Mol Cell Med 2018 28;7(4):251-257. Epub 2019 Feb 28.

Sanquin Blood Supply Organization, and Landsteiner Laboratory, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.22088/IJMCM.BUMS.7.4.251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709932PMC
February 2019

Neutrophils as myeloid-derived suppressor cells.

Eur J Clin Invest 2018 Nov 7;48 Suppl 2:e12989. Epub 2018 Aug 7.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/eci.12989DOI Listing
November 2018

Human T17 cell development requires processing of dendritic cell-derived CXCL8 by neutrophil elastase.

J Allergy Clin Immunol 2018 06 31;141(6):2286-2289.e5. Epub 2018 Jan 31.

Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2018.01.003DOI Listing
June 2018

Substitution of Mannan-Binding Lectin (MBL)-Deficient Serum With Recombinant MBL Results in the Formation of New MBL/MBL-Associated Serine Protease Complexes.

Front Immunol 2018 27;9:1406. Epub 2018 Jun 27.

Department of Immunopathology, Sanquin Blood Supply, Division Research and Landsteiner Laboratory of the Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.01406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030254PMC
June 2018

Normal MRI findings of the knee in patients with clinically active juvenile idiopathic arthritis.

Eur J Radiol 2018 May 6;102:36-40. Epub 2018 Mar 6.

Department of Pediatric Hematology, Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital AMC, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2018.02.027DOI Listing
May 2018

Contrast-enhanced MRI findings of the knee in healthy children; establishing normal values.

Eur Radiol 2018 Mar 6;28(3):1167-1174. Epub 2017 Oct 6.

Department of Radiology and Nuclear Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00330-017-5067-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811591PMC
March 2018

Juvenile idiopathic arthritis: magnetic resonance imaging of the clinically unaffected knee.

Pediatr Radiol 2018 03 6;48(3):333-340. Epub 2018 Jan 6.

Department of Radiology and Nuclear Medicine, Academic Medical Center, University of Amsterdam, Department of Radiology (G1-213), Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1007/s00247-017-4059-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823947PMC
March 2018

A false-carrier state for the c.579G>A mutation in the NCF1 gene in Ashkenazi Jews.

J Med Genet 2018 03 13;55(3):166-172. Epub 2018 Jan 13.

The Danek Gertner Institute of Human Genetics, Sheba Medical Center, Ramat Gan, Israel and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1136/jmedgenet-2017-105022DOI Listing
March 2018

Genetic variation of human neutrophil Fcγ receptors and SIRPα in antibody-dependent cellular cytotoxicity towards cancer cells.

Eur J Immunol 2018 02 2;48(2):344-354. Epub 2017 Nov 2.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.201747215DOI Listing
February 2018

Abnormalities of T-cell receptor repertoire in CD4 regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity.

J Allergy Clin Immunol 2017 12 31;140(6):1739-1743.e7. Epub 2017 Aug 31.

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5911433PMC
December 2017

Giant aneurysms: A gender-specific complication of Kawasaki disease?

J Cardiol 2017 Oct 18;70(4):359-365. Epub 2017 Mar 18.

Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jjcc.2016.12.014DOI Listing
October 2017

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

Hum Mutat 2017 10 15;38(10):1402-1411. Epub 2017 Jun 15.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://doi.wiley.com/10.1002/humu.23271
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http://dx.doi.org/10.1002/humu.23271DOI Listing
October 2017

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56 NKG2A Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Front Immunol 2017 10;8:1244. Epub 2017 Oct 10.

Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.01
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http://dx.doi.org/10.3389/fimmu.2017.01244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641412PMC
October 2017

Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma.

Front Immunol 2017 18;8:1328. Epub 2017 Oct 18.

Department of Immunopathology, Sanquin Research and Landsteiner Laboratory of the Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2017.01328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651247PMC
October 2017

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues.

Cell Rep 2017 Sep 7;20(12):2906-2920. Epub 2017 Sep 7.

Molecular Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia; The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.08.068DOI Listing
September 2017

Construct validity of pixel-by-pixel DCE-MRI: Correlation with conventional MRI scores in juvenile idiopathic arthritis.

Eur J Radiol 2017 Sep 14;94:1-5. Epub 2017 Jul 14.

Department of Radiology and Nuclear Medicine,Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejrad.2017.07.003DOI Listing
September 2017

Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor Profile.

J Immunol 2017 07 31;199(1):204-211. Epub 2017 May 31.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, 1066 CX Amsterdam, the Netherlands.

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http://dx.doi.org/10.4049/jimmunol.1700116DOI Listing
July 2017

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56 NKG2A Cells, and Yet Display Increased Degranulation and Higher Perforin Content.

Front Immunol 2017 17;8:798. Epub 2017 Jul 17.

Laboratory of Host Defenses, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.00
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http://dx.doi.org/10.3389/fimmu.2017.00798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5511964PMC
July 2017

Mutation in an exonic splicing enhancer site causing chronic granulomatous disease.

Blood Cells Mol Dis 2017 07 18;66:50-57. Epub 2017 Aug 18.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2017.08.012DOI Listing
July 2017

The cellular immune system comes of age.

J Allergy Clin Immunol 2017 06 22;139(6):1793-1794. Epub 2017 Mar 22.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Pediatric Hematology, Immunology, and Infectious Disease, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2017.02.023DOI Listing
June 2017

Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells.

Blood Adv 2017 Jun 26;1(14):875-886. Epub 2017 May 26.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://www.bloodadvances.org/lookup/doi/10.1182/bloodadvance
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http://dx.doi.org/10.1182/bloodadvances.2017004671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737592PMC
June 2017

Dexamethasone promotes granulocyte mobilization by prolonging the half-life of granulocyte-colony-stimulating factor in healthy donors for granulocyte transfusions.

Transfusion 2017 03 28;57(3):674-684. Epub 2016 Dec 28.

Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam.

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http://dx.doi.org/10.1111/trf.13941DOI Listing
March 2017

Dynamic contrast-enhanced magnetic resonance imaging can play a role in predicting flare in juvenile idiopathic arthritis.

Eur J Radiol 2017 Mar 4;88:77-81. Epub 2017 Jan 4.

Department of Pediatric Hematology, Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Academic Medical Center Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejrad.2017.01.003DOI Listing
March 2017

RhIg-prophylaxis is not influenced by FCGR2/3 polymorphisms involved in red blood cell clearance.

Blood 2017 02 12;129(8):1045-1048. Epub 2017 Jan 12.

Department of Experimental Immunohematology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2016-05-716365DOI Listing
February 2017

Higher subcortical and white matter cerebral blood flow in perinatally HIV-infected children.

Medicine (Baltimore) 2017 Feb;96(7):e5891

aDepartment of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital/Academic Medical Center, University of Amsterdam bDepartment of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands cCognitive Neurology Research Unit, Sunnybrook Health Sciences Center, Toronto, Canada dDepartment of Global Health, Academic Medical Center, University of Amsterdam, and Amsterdam Institute for Global Health and Development eDepartment of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam, Academic Medical Center fHIV Monitoring Foundation, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/MD.0000000000005891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319495PMC
February 2017

Humoral Immunodeficiency with Hypotonia, Feeding Difficulties, Enteropathy, and Mild Eczema Caused by a Classical Mutation.

Front Pediatr 2017 27;5:37. Epub 2017 Feb 27.

Department of Pediatric Hematology, Immunology, Rheumatology and Infectious Diseases, Emma Children's Hospital, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands; Department of Clinical Genetics, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fped.2017.00037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326763PMC
February 2017

Immune checkpoint blockade: Which switches to hit and how much?

Immunol Lett 2016 12 20;180:73-74. Epub 2016 Sep 20.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2016.08.014DOI Listing
December 2016

Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems.

Cell Rep 2016 11;17(8):2101-2111

CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Baldiri i Reixac 4, Barcelona 08028, Spain; Universitat Pompeu Fabra (UPF), Barcelona 08002, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889099PMC
November 2016

Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells.

Cell 2016 11;167(5):1398-1414.e24

Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, Strangeways Research Laboratory, University of Cambridge, Wort's Causeway, Cambridge CB1 8RN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674163144
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http://dx.doi.org/10.1016/j.cell.2016.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119954PMC
November 2016

The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

Cell 2016 11;167(5):1415-1429.e19

Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Long Road, Cambridge CB2 0PT, UK; Department of Human Genetics, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, University of Cambridge, Strangeways Research Laboratory, Wort's Causeway, Cambridge CB1 8RN, UK; British Heart Foundation Centre of Excellence, Division of Cardiovascular Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5300907PMC
November 2016

Phenotypic and Functional Comparison of Class Switch Recombination Deficiencies with a Subgroup of Common Variable Immunodeficiencies.

J Clin Immunol 2016 10 2;36(7):656-66. Epub 2016 Aug 2.

Department of Pediatric Hematology, Immunology and Infectious Diseases, Academic Medical Center (AMC), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10875-016-0321-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018261PMC
October 2016

The High Prevalence of Functional Complement Defects Induced by Chemotherapy.

Front Immunol 2016 17;7:420. Epub 2016 Oct 17.

Academic Medical Center (AMC), Emma Children's Hospital, University of Amsterdam, Amsterdam, Netherlands; Sanquin Research and Landsteiner Laboratory AMC, Department of Blood Cell Research, University of Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2016.00420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066094PMC
October 2016

Proinflammatory cytokine response toward fungi but not bacteria in chronic granulomatous disease.

J Allergy Clin Immunol 2016 09 5;138(3):928-930.e4. Epub 2016 May 5.

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands; Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2016.03.035DOI Listing
September 2016

How neutrophils kill fungi.

Immunol Rev 2016 09;273(1):299-311

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/imr.12454DOI Listing
September 2016

Neutrophils in cancer.

Immunol Rev 2016 09;273(1):312-28

Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/imr.12444DOI Listing
September 2016

Noncirrhotic Portal Hypertension in Perinatally HIV-infected Adolescents Treated With Didanosine-containing Antiretroviral Regimens in Childhood.

Pediatr Infect Dis J 2016 Aug;35(8):e248-52

From the *Department of Pediatric Hematology, Immunology and Infectious Diseases, and †Department of Pathology, Emma Children's Hospital, Academic Medical Center (AMC), Amsterdam, The Netherlands; ‡Department of Pathology, MCH-Bronovo Hospital, The Hague, The Netherlands; §Faculty of Medicine, Chulalongkorn University and HIVNAT, Thai Red Cross AIDS Research Center, Bangkok, Thailand; ¶U.S. Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, & Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland, ‖Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom; Department of **Radiodiagnostics and ††Infectious Diseases, AMC; and ‡‡Department of Pediatric Gastroenterology, Emma Children's Hospital, AMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/INF.0000000000001202DOI Listing
August 2016

In-utero exposure to tenofovir is associated with impaired fetal and infant growth: need for follow-up studies in combination antiretroviral therapy/HIV-exposed infants.

AIDS 2016 08;30(13):2135-7

aDepartment of Paediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Centre (AMC), University of Amsterdam (UvA), Amsterdam bDepartment of Paediatrics, Amphia Hospital, Breda cDepartment of Internal Medicine dDepartment of Gynaecology and Obstetrics, AMC, UvA eHIV Monitoring Foundation fDepartment of Experimental Immunology, AMC, UvA, Amsterdam, The Netherlands. *Henriette J. Scherpbier and Madeleine J. Bunders contributed equally to the writing of this article.

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http://dx.doi.org/10.1097/QAD.0000000000001156DOI Listing
August 2016

Killer immunoglobulin receptor genes in spondyloarthritis.

Curr Opin Rheumatol 2016 Jul;28(4):368-75

aSanquin, Department of Blood Cell Research and Landsteiner Laboratory of Immunology bDepartment of Pediatric Hematology, Immunology, Rheumatology and Infectious Disease, Emma Children's Hospital cDepartment of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1097/BOR.0000000000000302DOI Listing
July 2016

Extracardial Vasculopathy After Kawasaki Disease: A Long-Term Follow-up Study.

J Am Heart Assoc 2016 07 5;5(7). Epub 2016 Jul 5.

Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Center (AMC), Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/JAHA.116.003414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015378PMC
July 2016