Sylvan Baca

Sylvan Baca

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Sylvan Baca

Sylvan Baca

Publications by authors named "Sylvan Baca"

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12Publications

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CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.

Authors:
Reyaz Ur Rasool Ramakrishnan Natesan Qu Deng Shweta Aras Priti Lal Samuel Sander Effron Erick Mitchell-Velasquez Jessica M Posimo Shannon Carskadon Sylvan C Baca Mark M Pomerantz Javed Siddiqui Lauren E Schwartz Daniel J Lee Nallasivam Palanisamy Goutham Narla Robert B Den Matthew L Freedman Donita C Brady Irfan A Asangani

Cancer Discov 2019 Nov 29;9(11):1538-1555. Epub 2019 Aug 29.

Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0189DOI Listing
November 2019

Qualifiers of atypia in the cytologic diagnosis of thyroid nodules are associated with different Afirma gene expression classifier results and clinical outcomes.

Authors:
Sylvan C Baca Kristine S Wong Kyle C Strickland Howard T Heller Matthew I Kim Justine A Barletta Edmund S Cibas Jeffrey F Krane Ellen Marqusee Trevor E Angell

Cancer Cytopathol 2017 05 2;125(5):313-322. Epub 2017 Feb 2.

Thyroid Section, Division of Endocrinology, Hypertension, and Diabetes, The Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncy.21827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484344PMC
May 2017

Erratum to: Unraveling the clonal hierarchy of somatic genomic aberrations.

Authors:
Davide Prandi Sylvan C Baca Alessandro Romanel Christopher E Barbieri Juan-Miguel Mosquera Jacqueline Fontugne Himisha Beltran Andrea Sboner Levi A Garraway Mark A Rubin Francesca Demichelis

Genome Biol 2017 05 2;18(1):80. Epub 2017 May 2.

Centre for Integrative Biology, University of Trento, Povo Trento, 38123, Italy.

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http://dx.doi.org/10.1186/s13059-017-1183-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412043PMC
May 2017

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Authors:
Jennifer A Perry Adam Kiezun Peter Tonzi Eliezer M Van Allen Scott L Carter Sylvan C Baca Glenn S Cowley Ami S Bhatt Esther Rheinbay Chandra Sekhar Pedamallu Elena Helman Amaro Taylor-Weiner Aaron McKenna David S DeLuca Michael S Lawrence Lauren Ambrogio Carrie Sougnez Andrey Sivachenko Loren D Walensky Nikhil Wagle Jaume Mora Carmen de Torres Cinzia Lavarino Simone Dos Santos Aguiar Jose Andres Yunes Silvia Regina Brandalise Gabriela Elisa Mercado-Celis Jorge Melendez-Zajgla Rocío Cárdenas-Cardós Liliana Velasco-Hidalgo Charles W M Roberts Levi A Garraway Carlos Rodriguez-Galindo Stacey B Gabriel Eric S Lander Todd R Golub Stuart H Orkin Gad Getz Katherine A Janeway

Proc Natl Acad Sci U S A 2014 Dec 15;111(51):E5564-73. Epub 2014 Dec 15.

Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215; Department of Pediatrics,

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http://dx.doi.org/10.1073/pnas.1419260111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280630PMC
December 2014

Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.

Authors:
Jean-Philippe P Theurillat Namrata D Udeshi Wesley J Errington Tanya Svinkina Sylvan C Baca Marius Pop Peter J Wild Mirjam Blattner Anna C Groner Mark A Rubin Holger Moch Gilbert G Prive Steven A Carr Levi A Garraway

Science 2014 Oct 2;346(6205):85-89. Epub 2014 Oct 2.

The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1126/science.1250255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257137PMC
October 2014

Unraveling the clonal hierarchy of somatic genomic aberrations.

Authors:
Davide Prandi Sylvan C Baca Alessandro Romanel Christopher E Barbieri Juan-Miguel Mosquera Jacqueline Fontugne Himisha Beltran Andrea Sboner Levi A Garraway Mark A Rubin Francesca Demichelis

Genome Biol 2014 Aug 26;15(8):439. Epub 2014 Aug 26.

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http://dx.doi.org/10.1186/s13059-014-0439-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167267PMC
August 2014

Mutational heterogeneity in cancer and the search for new cancer-associated genes.

Authors:
Michael S Lawrence Petar Stojanov Paz Polak Gregory V Kryukov Kristian Cibulskis Andrey Sivachenko Scott L Carter Chip Stewart Craig H Mermel Steven A Roberts Adam Kiezun Peter S Hammerman Aaron McKenna Yotam Drier Lihua Zou Alex H Ramos Trevor J Pugh Nicolas Stransky Elena Helman Jaegil Kim Carrie Sougnez Lauren Ambrogio Elizabeth Nickerson Erica Shefler Maria L Cortés Daniel Auclair Gordon Saksena Douglas Voet Michael Noble Daniel DiCara Pei Lin Lee Lichtenstein David I Heiman Timothy Fennell Marcin Imielinski Bryan Hernandez Eran Hodis Sylvan Baca Austin M Dulak Jens Lohr Dan-Avi Landau Catherine J Wu Jorge Melendez-Zajgla Alfredo Hidalgo-Miranda Amnon Koren Steven A McCarroll Jaume Mora Brian Crompton Robert Onofrio Melissa Parkin Wendy Winckler Kristin Ardlie Stacey B Gabriel Charles W M Roberts Jaclyn A Biegel Kimberly Stegmaier Adam J Bass Levi A Garraway Matthew Meyerson Todd R Golub Dmitry A Gordenin Shamil Sunyaev Eric S Lander Gad Getz

Nature 2013 Jul 16;499(7457):214-218. Epub 2013 Jun 16.

The Broad Institute of MIT and Harvard, Cambridge, MA, 02141, USA.

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https://dash.harvard.edu/bitstream/handle/1/11879842/3919509
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http://www.nature.com/doifinder/10.1038/nature12213
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http://dx.doi.org/10.1038/nature12213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919509PMC
July 2013

Punctuated evolution of prostate cancer genomes.

Authors:
Sylvan C Baca Davide Prandi Michael S Lawrence Juan Miguel Mosquera Alessandro Romanel Yotam Drier Kyung Park Naoki Kitabayashi Theresa Y MacDonald Mahmoud Ghandi Eliezer Van Allen Gregory V Kryukov Andrea Sboner Jean-Philippe Theurillat T David Soong Elizabeth Nickerson Daniel Auclair Ashutosh Tewari Himisha Beltran Robert C Onofrio Gunther Boysen Candace Guiducci Christopher E Barbieri Kristian Cibulskis Andrey Sivachenko Scott L Carter Gordon Saksena Douglas Voet Alex H Ramos Wendy Winckler Michelle Cipicchio Kristin Ardlie Philip W Kantoff Michael F Berger Stacey B Gabriel Todd R Golub Matthew Meyerson Eric S Lander Olivier Elemento Gad Getz Francesca Demichelis Mark A Rubin Levi A Garraway

Cell 2013 Apr;153(3):666-77

Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.cell.2013.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690918PMC
April 2013

Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.

Authors:
Austin M Dulak Steven E Schumacher Jasper van Lieshout Yu Imamura Cameron Fox Byoungyong Shim Alex H Ramos Gordon Saksena Sylvan C Baca Jose Baselga Josep Tabernero Jordi Barretina Peter C Enzinger Giovanni Corso Franco Roviello Lin Lin Santhoshi Bandla James D Luketich Arjun Pennathur Matthew Meyerson Shuji Ogino Ramesh A Shivdasani David G Beer Tony E Godfrey Rameen Beroukhim Adam J Bass

Cancer Res 2012 Sep 2;72(17):4383-93. Epub 2012 Jul 2.

Departments of Medical Oncology, Cancer Biology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432726PMC
September 2012

The genomic landscape of prostate cancer.

Authors:
Sylvan C Baca Levi A Garraway

Front Endocrinol (Lausanne) 2012 16;3:69. Epub 2012 May 16.

Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.3389/fendo.2012.00069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355898PMC
July 2012

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.

Authors:
Christopher E Barbieri Sylvan C Baca Michael S Lawrence Francesca Demichelis Mirjam Blattner Jean-Philippe Theurillat Thomas A White Petar Stojanov Eliezer Van Allen Nicolas Stransky Elizabeth Nickerson Sung-Suk Chae Gunther Boysen Daniel Auclair Robert C Onofrio Kyung Park Naoki Kitabayashi Theresa Y MacDonald Karen Sheikh Terry Vuong Candace Guiducci Kristian Cibulskis Andrey Sivachenko Scott L Carter Gordon Saksena Douglas Voet Wasay M Hussain Alex H Ramos Wendy Winckler Michelle C Redman Kristin Ardlie Ashutosh K Tewari Juan Miguel Mosquera Niels Rupp Peter J Wild Holger Moch Colm Morrissey Peter S Nelson Philip W Kantoff Stacey B Gabriel Todd R Golub Matthew Meyerson Eric S Lander Gad Getz Mark A Rubin Levi A Garraway

Nat Genet 2012 May 20;44(6):685-9. Epub 2012 May 20.

Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York, USA.

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http://dx.doi.org/10.1038/ng.2279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673022PMC
May 2012

Determining membrane capacitance by dynamic control of droplet interface bilayer area.

Authors:
Linda C M Gross Andrew J Heron Sylvan C Baca Mark I Wallace

Langmuir 2011 Dec 2;27(23):14335-42. Epub 2011 Nov 2.

Department of Chemistry, University of Oxford, Chemistry Research Laboratory, Mansfield Road, Oxford OX1 3TA.

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http://dx.doi.org/10.1021/la203081vDOI Listing
December 2011