Syd Johnson

Syd Johnson

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Syd Johnson

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A Belmont Report for Animals?

Camb Q Healthc Ethics 2020 Jan;29(1):19-37

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http://dx.doi.org/10.1017/S0963180119000732DOI Listing
January 2020

Neuroethics of the Nonhuman.

Authors:
L Syd M Johnson

AJOB Neurosci 2019 Jul-Sep;10(3):111-113

a Michigan Technological University.

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http://dx.doi.org/10.1080/21507740.2019.1632973DOI Listing
August 2019

Death by neurological criteria: expert definitions and lay misgivings.

Authors:
L Syd M Johnson

QJM 2017 May;110(5):267-270

From the Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.

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http://dx.doi.org/10.1093/qjmed/hcw181DOI Listing
May 2017

The Case for Reasonable Accommodation of Conscientious Objections to Declarations of Brain Death.

Authors:
L Syd M Johnson

J Bioeth Inq 2016 Mar 5;13(1):105-15. Epub 2016 Jan 5.

Humanities Department, Michigan Technological University, Walker 325, 1400 Townsend Drive, Houghton, MI, 49931, USA.

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http://dx.doi.org/10.1007/s11673-015-9683-zDOI Listing
March 2016

A legal fiction with real consequences.

Authors:
L Syd M Johnson

Am J Bioeth 2014 ;14(8):34-6

a Michigan Technological University.

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http://dx.doi.org/10.1080/15265161.2014.925156DOI Listing
November 2015

Defining New Therapeutics Using a More Immunocompetent Mouse Model of Antibody-Enhanced Dengue Virus Infection.

mBio 2015 Sep 15;6(5):e01316-15. Epub 2015 Sep 15.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, Missouri, USA

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http://dx.doi.org/10.1128/mBio.01316-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600115PMC
September 2015

Chikungunya viruses that escape monoclonal antibody therapy are clinically attenuated, stable, and not purified in mosquitoes.

J Virol 2014 Aug 14;88(15):8213-26. Epub 2014 May 14.

Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, USA Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri, USA

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http://jvi.asm.org/content/early/2014/05/08/JVI.01032-14.ful
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http://dx.doi.org/10.1128/JVI.01032-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4135940PMC
August 2014

Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.

PLoS Pathog 2014 Apr 17;10(4):e1004072. Epub 2014 Apr 17.

Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Biochemistry & Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990716PMC
April 2014

Protection by immunoglobulin dual-affinity retargeting antibodies against dengue virus.

J Virol 2013 Jul 8;87(13):7747-53. Epub 2013 May 8.

Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JVI.00327-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700316PMC
July 2013

Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope.

PLoS Pathog 2012 4;8(10):e1002930. Epub 2012 Oct 4.

Department of Pathology & Immunology, Washington University School of Medicine, Saint Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1002930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464233PMC
April 2013

Return to play guidelines cannot solve the football-related concussion problem.

Authors:
L Syd M Johnson

J Sch Health 2012 Apr;82(4):180-5

Humanities Department, Michigan Technological University, 1400 Townsend Drive, Houghton, MI 49931, USA.

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http://doi.wiley.com/10.1111/j.1746-1561.2011.00684.x
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http://dx.doi.org/10.1111/j.1746-1561.2011.00684.xDOI Listing
April 2012

Nonclinical evaluation of GMA161--an antihuman CD16 (FcγRIII) monoclonal antibody for treatment of autoimmune disorders in CD16 transgenic mice.

Toxicol Sci 2012 Jan 24;125(1):299-309. Epub 2011 Oct 24.

Biologics Research and Development, Genzyme Corporation, Framingham, Massachusetts 01701-9322, USA.

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http://dx.doi.org/10.1093/toxsci/kfr278DOI Listing
January 2012

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants.

J Exp Med 2011 Dec 12;208(13):2599-606. Epub 2011 Dec 12.

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20110740
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http://dx.doi.org/10.1084/jem.20110740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244041PMC
December 2011

Poorly neutralizing cross-reactive antibodies against the fusion loop of West Nile virus envelope protein protect in vivo via Fcgamma receptor and complement-dependent effector mechanisms.

J Virol 2011 Nov 14;85(22):11567-80. Epub 2011 Sep 14.

Department of Pathology & Immunology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.05859-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209272PMC
November 2011

The ethically dubious practice of thwarting the redemption of the condemned.

Authors:
L Syd M Johnson

Am J Bioeth 2011 Oct;11(10):9-10

Dalhousie University, Novel Tech Ethics, Halifax, Nova Scotia, Canada.

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http://www.tandfonline.com/doi/abs/10.1080/15265161.2011.603
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http://dx.doi.org/10.1080/15265161.2011.603800DOI Listing
October 2011

Concussion in youth ice hockey: it's time to break the cycle.

Authors:
L Syd M Johnson

CMAJ 2011 May 18;183(8):921-4. Epub 2011 Apr 18.

Novel Tech Ethics, Dalhousie University, Halifax, NS.

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http://dx.doi.org/10.1503/cmaj.110282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091900PMC
May 2011

The right to die in the minimally conscious state.

Authors:
L Syd M Johnson

J Med Ethics 2011 Mar 17;37(3):175-8. Epub 2010 Nov 17.

Dalhousie University, 1234 LeMarchant Street, Halifax, NS B3H3P7, Canada.

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http://dx.doi.org/10.1136/jme.2010.038877DOI Listing
March 2011

Genotype-specific neutralization and protection by antibodies against dengue virus type 3.

J Virol 2010 Oct 11;84(20):10630-43. Epub 2010 Aug 11.

Department of Medicine, Washington University School of Medicine, 660 South Euclid Ave., Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.01190-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950583PMC
October 2010

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

J Virol 2010 Sep 30;84(18):9227-39. Epub 2010 Jun 30.

Department of Medicine,Washington University School of Medicine, 660 South Euclid Ave., Box 8051, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1128/JVI.01087-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2937608PMC
September 2010

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice.

Proc Natl Acad Sci U S A 2010 Feb 1;107(6):2419-24. Epub 2010 Feb 1.

The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA.

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http://dx.doi.org/10.1073/pnas.0914503107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823901PMC
February 2010

Lethal antibody enhancement of dengue disease in mice is prevented by Fc modification.

PLoS Pathog 2010 Feb 12;6(2):e1000790. Epub 2010 Feb 12.

Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, California, United States of America.

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http://dx.plos.org/10.1371/journal.ppat.1000790
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http://dx.doi.org/10.1371/journal.ppat.1000790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820409PMC
February 2010

Capturing a flavivirus pre-fusion intermediate.

PLoS Pathog 2009 Nov 26;5(11):e1000672. Epub 2009 Nov 26.

Department of Biological Sciences, Purdue University, West Lafayette, Indiana, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776511PMC
November 2009

Enhancing the potency of therapeutic monoclonal antibodies via Fc optimization.

Adv Enzyme Regul 2008 3;48:152-64. Epub 2007 Dec 3.

MacroGenics, Inc., 1500 East Gude Drive, Rockville, MD 20850, USA.

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http://dx.doi.org/10.1016/j.advenzreg.2007.11.011DOI Listing
December 2008

Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological infection in a hamster model.

Antimicrob Agents Chemother 2007 Jul 23;51(7):2396-402. Epub 2007 Apr 23.

Institute for Antiviral Research, Animal, Dairy, and Veterinary Sciences Department, Utah State University, 4700 Old Main Hill, Logan, UT 84322-4700, USA.

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http://dx.doi.org/10.1128/AAC.00147-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913249PMC
July 2007

Humanized monoclonal antibody against West Nile virus envelope protein administered after neuronal infection protects against lethal encephalitis in hamsters.

J Infect Dis 2006 Nov 22;194(9):1300-8. Epub 2006 Sep 22.

Institute for Antiviral Research, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84322-4700, USA.

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https://academic.oup.com/jid/article-lookup/doi/10.1086/5082
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http://dx.doi.org/10.1086/508293DOI Listing
November 2006

Structural basis of West Nile virus neutralization by a therapeutic antibody.

Nature 2005 Sep;437(7059):764-9

Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://www.nature.com/articles/nature03956
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http://dx.doi.org/10.1038/nature03956DOI Listing
September 2005

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus.

Nat Med 2005 May 24;11(5):522-30. Epub 2005 Apr 24.

Department of Molecular Microbiology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8051, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1038/nm1240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1458527PMC
May 2005