Publications by authors named "Swasti Jain"

8 Publications

  • Page 1 of 1

Coronary arteritis as a cause of sudden cardiac death in a young girl.

Autops Case Rep 2021 20;11:e2021310. Epub 2021 Aug 20.

Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, Department of Pathology, New Delhi, India.

A case of probable coronary arteritis in a young girl who died suddenly and unexpectedly is presented. The histologic presentation of the disorder is discussed, especially the differential diagnosis of arteritis of the coronary arteries with an emphasis on tuberculosis (TB). TB myocarditis with or without concomitant lung involvement is rare, and tubercular coronary arteritis without underlying pulmonary Koch's disease is all the rarer. We herein describe a case where the cause of death was ascertained on post-mortem examination.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.4322/acr.2021.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8387068PMC
August 2021

Comparative evaluation of squash smear and frozen section in the intraoperative diagnosis of central nervous system tumours.

Cytopathology 2021 Aug 14. Epub 2021 Aug 14.

Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Background: The squash smear technique was introduced into intra-operative neurosurgical diagnosis as early as 1930. It is becoming increasingly popular in the diagnosis of central nervous system (CNS) lesions, and is fairly accurate even with a small sample. The current study assesses the accuracy and utility of the squash smear and frozen section (FS) techniques in intraoperative consultations. Correlations with histopathological diagnoses are presented.

Aims: To compare two intra-operative diagnostic techniques-squash smear cytology and FS examination-in the context of central nervous system tumours.

Materials And Methods: A total of 53 cases of CNS tumours were included in the study, and all were subjected to squash smear examination. FS examinations were conducted for 39 of these samples. The results of the two techniques were compared and correlated with histopathological diagnoses. The observed results were then analysed using SPSS software.

Results: The most common primary CNS tumours were gliomas and meningiomas (28.3% each). The sensitivity, specificity, positive predictive value and negative predictive value for squash cytology were 86.67%, 87.5%, 81.25% and 91.3%, and for FS were 91.67%, 93.10%, 91.67%, 93.10%, respectively, with a corresponding comparative P-value of 0.56 (insignificant). Cytological diagnosis showed complete correlation with histopathological diagnosis in 39 cases (73.58%), partial correlation in eight cases (15.1%) and no correlation in six cases (11.32%). FS diagnosis showed complete correlation in 29 cases (74.35%), partial correlation in eight cases (20.5%) and no correlation in two cases (5.1%).

Conclusion: Squash smear is a rapid, self-sufficient and cost-effective method for the intraoperative diagnosis of CNS tumours. The squash smear and FS techniques are complementary procedures that assist the pathologist in reaching a diagnosis.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1111/cyt.13049DOI Listing
August 2021

Cytomorphological spectrum of cysticercosis: A study of 26 cases.

Cytopathology 2021 Jul 31. Epub 2021 Jul 31.

Department of Pathology, Atal Bihari Vajpayi Institute of Medical Sciences & Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Background: Cysticercosis is a systemic parasitic disease caused by the larval stage of Taenia solium. It is the most common parasitic disease worldwide. Fine needle aspiration cytology can play an important role in prompt recognition of this disease.

Objective: To study the role of FNAC in the diagnosis of cysticercosis.

Materials And Methods: This study included 26 patients with parasitic infestation who presented with palpable subcutaneous and intramuscular nodules at different sites. Their clinical presentations and fine needle aspiration cytomorphological features are reported.

Results: The age range of these patients was 7-60 years. The majority were males. The most commonly affected site was head and neck followed by upper extremity. Most of the cases were clinically misdiagnosed as lipomas, neurofibromas, lymphadenitis, epidermal inclusion cyst, sialadenitis, and soft tissue tumours. The aspirate was clear fluid in the majority of cases. All of the cases revealed fragments of bladder wall with associated granulomas in seven cases and giant cells in four cases. However, none of the case revealed hooklets.

Conclusion: Fine needle aspiration cytology can provide a simple, minimally invasive, low-cost, outpatient diagnostic technique for the diagnosis of cysticercosis, as cytological diagnosis is quite clear when the actual parasitic structures are identified in the smear.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1111/cyt.13043DOI Listing
July 2021

Cytological diagnosis of microfilariae in clinically unsuspected cases: A retrospective review of 12 cases.

Cytopathology 2021 Jul 17. Epub 2021 Jul 17.

Department of Pathology, Atal Bihari Vajpayee Institute Of Medical Sciences & Dr. Ram Manohar Lohia Hospital, New Delhi, India.

Background: Filariasis is a major health problem in India. Despite the high prevalence, microfilariae are rarely found in cytology smears. Most of the cases are incidentally found, solely or in association with other pathologies.

Aims And Objectives: This study was undertaken to analyse the prevalence and cytological findings of cases of incidentally found microfilariae in cytology smears (fine needle aspiration cytology [FNAC]/exfoliative cytology) from different parts of the body.

Materials And Methods: This was a retrospective study over 3 years, in which cases of microfilariae in aspirates from swelling of different locations, body fluids, and pap smears were reviewed, and the clinicopathological data analysed.

Results And Analysis: Out of 11 530 cases of FNAC, 8700 cases of fluid cytology, and 9000 of conventional cervicovaginal smears, 12 cases (0.04%) of incidental findings of microfilariae were documented in cytology smears. The cases were diagnosed from lymph node (one case), hand (one case), scrotal area (one case), axilla (one case), breast (one case), subcutaneous tissue (three cases), urine (three cases), and Pap smear (one case). We found eosinophilia in one case (8.3%) of filarial lesions. We found two cases of incidental findings of microfilariae in association with malignant lesions.

Conclusion: Cytology smear examination can play an important role in diagnosing occult filariasis in clinically unsuspected cases in association with other pathologies.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1111/cyt.13035DOI Listing
July 2021

Parietal swelling in an old female: A diagnostic conundrum.

Cytojournal 2021 6;18:11. Epub 2021 May 6.

Department of Pathology, ABVIMS and Dr. RML Hospital, New Delhi, India.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.25259/Cytojournal_35_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248008PMC
May 2021

Two unusual cases of hematuria reported on urine cytology.

Cytojournal 2021 16;18. Epub 2021 Apr 16.

Department of Pathology, ABVIMS and Dr. RML Hospital, New Delhi, India.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.25259/Cytojournal_9_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248244PMC
April 2021

A Rare Case of Epithelioid Myofibroblastoma of Breast Mimicking Lobular Carcinoma on Trucut Biopsy: a Diagnostic Pitfall and Literature Review.

Indian J Surg Oncol 2021 Apr 2;12(Suppl 1):201-204. Epub 2021 Mar 2.

Department of Pathology, ABVIMS and Dr. RML Hospital, New Delhi, India.

Epithelioid myofibroblastoma of the breast is a rare benign stromal tumor occurring in the postmenopausal females and elderly males. We report one such case in a 65-year-old female who underwent trucut biopsy from a well-defined right breast lump, which was misinterpreted as invasive lobular carcinoma on histology. Tumor showed mild to moderately pleomorphic tumor cells arranged in single file pattern, loosely dispersed and focally in sheets with inconspicuous nucleoli embedded in a fibrotic and hyalinized stroma. Immunohistochemistry for E-cadherin was negative further substantiating the morphological diagnosis. However, mastectomy specimen revealed it to be a case of epithelioid myofibroblastoma with the help of a large panel of immunohistochemical stains. In this report, we emphasize on the challenges of establishing this rare diagnosis mimicking lobular carcinoma, a diagnostic pitfall on trucut biopsy.
View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13193-021-01294-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8119572PMC
April 2021

Incidental Finding of Microfilaria in Cervicovaginal Liquid-Based Cytology Smear.

J Cytol 2020 Jan-Mar;37(1):65-66. Epub 2019 Dec 23.

Department of Pathology, PGIMER and Dr. RML Hospital, New Delhi, India.

View Article and Find Full Text PDF

Download full-text PDF

Source
http://dx.doi.org/10.4103/JOC.JOC_81_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6947733PMC
December 2019
-->