Publications by authors named "Svitlana Tyekucheva"

37Publications

A New Classification of Benign, Premalignant, and Malignant Endometrial Tissues Using Machine Learning Applied to 1413 Candidate Variables.

Int J Gynecol Pathol 2020 Jul;39(4):333-343

Department of Pathology, Brigham and Women's Hospital (M.J.D., D.J.P., G.L.M.) Department of Pathology, Harvard Medical School (D.J.P., G.L.M.) Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute (S.T.) Department of Biostatistics, Harvard T. H. Chan School of Public Health (S.T.), Boston, Massachusetts.

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http://dx.doi.org/10.1097/PGP.0000000000000615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884662PMC
July 2020

Transcriptome Deconvolution of Heterogeneous Tumor Samples with Immune Infiltration.

iScience 2018 Nov 2;9:451-460. Epub 2018 Nov 2.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2018.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249353PMC
November 2018

MYC Overexpression at the Protein and mRNA Level and Cancer Outcomes among Men Treated with Radical Prostatectomy for Prostate Cancer.

Cancer Epidemiol Biomarkers Prev 2018 02 15;27(2):201-207. Epub 2017 Nov 15.

Department of Oncologic Pathology, Dana-Farber Cancer Institute, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831163PMC
February 2018

Metabolic Profiling in Formalin-Fixed and Paraffin-Embedded Prostate Cancer Tissues.

Mol Cancer Res 2017 04 10;15(4):439-447. Epub 2017 Jan 10.

Department of Medical Oncology, Center of Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552883PMC
April 2017

Cholesterol Metabolism and Prostate Cancer Lethality.

Cancer Res 2016 08 20;76(16):4785-90. Epub 2016 Jun 20.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts. Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987257PMC
August 2016

Computational Reconstruction of NFκB Pathway Interaction Mechanisms during Prostate Cancer.

PLoS Comput Biol 2016 Apr 14;12(4):e1004820. Epub 2016 Apr 14.

Department of Biostatistics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1004820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831844PMC
April 2016

Association of prostate cancer risk variants with gene expression in normal and tumor tissue.

Cancer Epidemiol Biomarkers Prev 2015 Jan 4;24(1):255-60. Epub 2014 Nov 4.

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts. Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-0694-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294966PMC
January 2015

Comparative meta-analysis of prognostic gene signatures for late-stage ovarian cancer.

J Natl Cancer Inst 2014 Apr 3;106(5). Epub 2014 Apr 3.

Affiliations of authors: City University of New York School of Public Health, Hunter College, New York, NY (LW); Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA (LW, AC, MR, JD, XVW, ST, TR, BG, GP); Department of Biostatistics, Harvard School of Public Health, Boston, MA (LW, AC, CH, GP); Center for Cancer Research, Massachusetts General Hospital, Boston, MA (MB); Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada (BH); Medical Biophysics Department, University of Toronto, Toronto, Ontario, Canada (BH);Institute for Medical Information Sciences, Biometry, and Epidemiology, LMU Munich, Munich, Germany (CB).

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http://dx.doi.org/10.1093/jnci/dju049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580554PMC
April 2014

De novo fatty acid synthesis at the mitotic exit is required to complete cellular division.

Cell Cycle 2014 13;13(5):859-68. Epub 2014 Jan 13.

Department of Medical Oncology; Dana-Farber Cancer Institute; Harvard Medical School; Boston, MA USA; Center for Molecular Oncologic Pathology; Dana-Farber Cancer Institute; Harvard Medical School; Boston, MA USA; Department of Pathology; Brigham and Women's Hospital; Harvard Medical School; Boston, MA USA; The Broad Institute; Cambridge, MA USA; Division of Cancer Studies; King's College London; London, UK.

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http://dx.doi.org/10.4161/cc.27767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979921PMC
May 2015

A network of epigenetic regulators guides developmental haematopoiesis in vivo.

Nat Cell Biol 2013 Dec 17;15(12):1516-25. Epub 2013 Nov 17.

1] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Stem Cell Program and Division of Pediatric Hematology/Oncology, Children's Hospital Boston and Dana-Farber Cancer Institute, Howard Hughes Medical Institute, Boston, Massachusetts 02115, USA [3].

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http://dx.doi.org/10.1038/ncb2870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959952PMC
December 2013

Integrative eQTL-based analyses reveal the biology of breast cancer risk loci.

Cell 2013 Jan;152(3):633-41

Department of Medical Oncology, The Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.cell.2012.12.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165609PMC
January 2013

Integrating diverse genomic data using gene sets.

Genome Biol 2011 Oct 21;12(10):R105. Epub 2011 Oct 21.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2011-12-10-r105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3333775PMC
October 2011

Establishing the baseline level of repetitive element expression in the human cortex.

BMC Genomics 2011 Oct 10;12:495. Epub 2011 Oct 10.

Department of Biostatistics and Computational Biology, Dana-Farber CancerInstitute, 450 Brookline Ave, Boston, 02115, USA.

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http://dx.doi.org/10.1186/1471-2164-12-495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207997PMC
October 2011

Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.

Cancer Res 2009 Aug 4;69(16):6660-7. Epub 2009 Aug 4.

Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland 21218, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-09-1133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763410PMC
August 2009

Human-macaque comparisons illuminate variation in neutral substitution rates.

Genome Biol 2008 Apr 30;9(4):R76. Epub 2008 Apr 30.

Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, PA 16802, USA.

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http://dx.doi.org/10.1186/gb-2008-9-4-r76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643947PMC
April 2008

The genome-wide determinants of human and chimpanzee microsatellite evolution.

Genome Res 2008 Jan 21;18(1):30-8. Epub 2007 Nov 21.

Department of Biology, Penn State University, University Park, Pennsylvania 16802, USA.

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http://dx.doi.org/10.1101/gr.7113408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134767PMC
January 2008

A macaque's-eye view of human insertions and deletions: differences in mechanisms.

PLoS Comput Biol 2007 Sep 27;3(9):1772-82. Epub 2007 Jul 27.

Center for Comparative Genomics and Bioinformatics, Pennsylvania State University, University Park, Pennsylvania, USA.

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http://dx.doi.org/10.1371/journal.pcbi.0030176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976337PMC
September 2007

ESPERR: learning strong and weak signals in genomic sequence alignments to identify functional elements.

Genome Res 2006 Dec 19;16(12):1596-604. Epub 2006 Oct 19.

Center for Comparative Genomics and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

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http://www.genome.org/cgi/doi/10.1101/gr.4537706
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http://dx.doi.org/10.1101/gr.4537706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1665643PMC
December 2006

Genomic environment predicts expression patterns on the human inactive X chromosome.

PLoS Genet 2006 Sep 3;2(9):e151. Epub 2006 Aug 3.

Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1584270PMC
September 2006

Strong and weak male mutation bias at different sites in the primate genomes: insights from the human-chimpanzee comparison.

Mol Biol Evol 2006 Mar 9;23(3):565-73. Epub 2005 Nov 9.

Department of Computer Science and Engineering, Penn State University, USA.

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http://academic.oup.com/mbe/article/23/3/565/1110290/Strong-
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http://dx.doi.org/10.1093/molbev/msj060DOI Listing
March 2006