Sven Nelander

Sven Nelander

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Sven Nelander

Publications by authors named "Sven Nelander"

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LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients.

Authors:
Yuan Xie Anders Sundström Naga P Maturi E-Jean Tan Voichita D Marinescu Malin Jarvius Malin Tirfing Chuan Jin Lei Chen Magnus Essand Fredrik J Swartling Sven Nelander Yiwen Jiang Lene Uhrbom

J Pathol 2019 Feb 10;247(2):228-240. Epub 2019 Jan 10.

Department of Immunology, Genetics and Pathology, Uppsala University and Science for Life Laboratory, Rudbeck Laboratory, Uppsala, Sweden.

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http://doi.wiley.com/10.1002/path.5186
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http://dx.doi.org/10.1002/path.5186DOI Listing
February 2019

Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes.

Authors:
Holger Weishaupt Patrik Johansson Anders Sundström Zelmina Lubovac-Pilav Björn Olsson Sven Nelander Fredrik J Swartling

Bioinformatics 2019 Feb 1. Epub 2019 Feb 1.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btz066DOI Listing
February 2019

Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma.

Authors:
Damian J Matuszewski Carolina Wählby Cecilia Krona Sven Nelander Ida-Maria Sintorn

SLAS Discov 2018 Dec 3;23(10):1030-1039. Epub 2018 Aug 3.

2 Centre for Image Analysis, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1177/2472555218791414DOI Listing
December 2018

Primary glioblastoma cells for precision medicine: a quantitative portrait of genomic (in)stability during the first 30 passages.

Authors:
Sathishkumar Baskaran Markus Mayrhofer Hanna Göransson Kultima Tobias Bergström Lioudmila Elfineh Lucia Cavelier Anders Isaksson Sven Nelander

Neuro Oncol 2018 Jul;20(8):1080-1091

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Sweden.

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https://academic.oup.com/neuro-oncology/advance-article/doi/
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http://dx.doi.org/10.1093/neuonc/noy024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280139PMC
July 2018

FC1000: normalized gene expression changes of systematically perturbed human cells.

Authors:
Ingrid M Lönnstedt Sven Nelander

Stat Appl Genet Mol Biol 2017 09;16(4):217-242

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http://dx.doi.org/10.1515/sagmb-2016-0072DOI Listing
September 2017

Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.

Authors:
Vita Fedele Fangping Dai Anie P Masilamani Dieter H Heiland Eva Kling Ana M Gätjens-Sanchez Roberto Ferrarese Leonardo Platania Doostkam Soroush Hyunsoo Kim Sven Nelander Astrid Weyerbrock Marco Prinz Andrea Califano Antonio Iavarone Markus Bredel Maria S Carro

Mol Cancer Res 2017 08 16;15(8):998-1011. Epub 2017 May 16.

Department of Neurosurgery, Medical Center, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967621PMC
August 2017

Retraction Notice to: Vulnerability of Glioblastoma Cells to Catastrophic Vacuolization and Death Induced by a Small Molecule.

Authors:
Satish Srinivas Kitambi Enrique M Toledo Dmitry Usoskin Shimei Wee Aditya Harisankar Richard Svensson Kristmundur Sigmundsson Christina Kalderén Mia Niklasson Soumi Kundu Sergi Aranda Bengt Westermark Lene Uhrbom Michael Andäng Peter Damberg Sven Nelander Ernest Arenas Per Artursson Julian Walfridsson Karin Forsberg Nilsson Lars G J Hammarström Patrik Ernfors

Cell 2017 07;170(2):407

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http://dx.doi.org/10.1016/j.cell.2017.06.044DOI Listing
July 2017

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.

Authors:
Yiwen Jiang Voichita Dana Marinescu Yuan Xie Malin Jarvius Naga Prathyusha Maturi Caroline Haglund Sara Olofsson Nanna Lindberg Tommie Olofsson Caroline Leijonmarck Göran Hesselager Irina Alafuzoff Mårten Fryknäs Rolf Larsson Sven Nelander Lene Uhrbom

Cell Rep 2017 05;19(5):1080-1081

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http://dx.doi.org/10.1016/j.celrep.2017.04.053DOI Listing
May 2017

Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.

Authors:
Mia Niklasson Gianluca Maddalo Zuzana Sramkova Ercan Mutlu Shimei Wee Petra Sekyrova Linnéa Schmidt Nicolas Fritz Ivar Dehnisch Gregorios Kyriatzis Michaela Krafcikova Brittany B Carson Jennifer M Feenstra Voichita D Marinescu Anna Segerman Martin Haraldsson Anna-Lena Gustavsson Lars G J Hammarström Annika Jenmalm Jensen Lene Uhrbom A F Maarten Altelaar Sten Linnarsson Per Uhlén Lukas Trantirek C Theresa Vincent Sven Nelander Per Øyvind Enger Michael Andäng

Cancer Res 2017 04 13;77(7):1741-1752. Epub 2017 Jan 13.

Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2274DOI Listing
April 2017

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus.

Authors:
Mohanraj Ramachandran Di Yu Matheus Dyczynski Sathishkumar Baskaran Lei Zhang Aleksei Lulla Valeria Lulla Sirle Saul Sven Nelander Anna Dimberg Andres Merits Justyna Leja-Jarblad Magnus Essand

Clin Cancer Res 2017 Mar 16;23(6):1519-1530. Epub 2016 Sep 16.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0925DOI Listing
March 2017

c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas.

Authors:
Dieter H Heiland Roberto Ferrarese Rainer Claus Fangping Dai Anie P Masilamani Eva Kling Astrid Weyerbrock Teresia Kling Sven Nelander Maria S Carro

Oncotarget 2017 Jan;8(4):6940-6954

Department of Neurosurgery, Medical Center - University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.18632/oncotarget.14330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351681PMC
January 2017

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.

Authors:
Yiwen Jiang Voichita Dana Marinescu Yuan Xie Malin Jarvius Naga Prathyusha Maturi Caroline Haglund Sara Olofsson Nanna Lindberg Tommie Olofsson Caroline Leijonmarck Göran Hesselager Irina Alafuzoff Mårten Fryknäs Rolf Larsson Sven Nelander Lene Uhrbom

Cell Rep 2017 01;18(4):977-990

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 75185 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.01.003DOI Listing
January 2017

Case-specific potentiation of glioblastoma drugs by pterostilbene.

Authors:
Linnéa Schmidt Sathishkumar Baskaran Patrik Johansson Narendra Padhan Damian Matuszewski Lydia C Green Ludmila Elfineh Shimei Wee Maria Häggblad Ulf Martens Bengt Westermark Karin Forsberg-Nilsson Lene Uhrbom Lena Claesson-Welsh Michael Andäng Ida-Maria Sintorn Bo Lundgren Ingrid Lönnstedt Cecilia Krona Sven Nelander

Oncotarget 2016 11;7(45):73200-73215

Life Laboratory, Uppsala University, Uppsala Sweden.

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http://dx.doi.org/10.18632/oncotarget.12298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341973PMC
November 2016

Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma.

Authors:
Teresia Kling Roberto Ferrarese Darren Ó hAilín Patrik Johansson Dieter Henrik Heiland Fangping Dai Ioannis Vasilikos Astrid Weyerbrock Rebecka Jörnsten Maria Stella Carro Sven Nelander

EBioMedicine 2016 Oct 18;12:72-85. Epub 2016 Sep 18.

Dept of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbecklaboratoriet, SE-751 85 Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2016.08.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078587PMC
October 2016

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.

Authors:
Narendra Padhan Torbjörn E M Nordling Magnus Sundström Peter Åkerud Helgi Birgisson Peter Nygren Sven Nelander Lena Claesson-Welsh

BMC Cancer 2016 Aug 25;16(1):683. Epub 2016 Aug 25.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsv 20, Uppsala, 751 85, Sweden.

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http://dx.doi.org/10.1186/s12885-016-2725-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000422PMC
August 2016

Origin of the U87MG glioma cell line: Good news and bad news.

Authors:
Marie Allen Mia Bjerke Hanna Edlund Sven Nelander Bengt Westermark

Sci Transl Med 2016 08;8(354):354re3

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, SE-751 85 Uppsala, Sweden.

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http://stm.sciencemag.org/content/scitransmed/8/354/354re3.f
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http://dx.doi.org/10.1126/scitranslmed.aaf6853DOI Listing
August 2016

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.

Authors:
Jonathan S Mitchell Ni Li Niels Weinhold Asta Försti Mina Ali Mark van Duin Gudmar Thorleifsson David C Johnson Bowang Chen Britt-Marie Halvarsson Daniel F Gudbjartsson Rowan Kuiper Owen W Stephens Uta Bertsch Peter Broderick Chiara Campo Hermann Einsele Walter A Gregory Urban Gullberg Marc Henrion Jens Hillengass Per Hoffmann Graham H Jackson Ellinor Johnsson Magnus Jöud Sigurður Y Kristinsson Stig Lenhoff Oleg Lenive Ulf-Henrik Mellqvist Gabriele Migliorini Hareth Nahi Sven Nelander Jolanta Nickel Markus M Nöthen Thorunn Rafnar Fiona M Ross Miguel Inacio da Silva Filho Bhairavi Swaminathan Hauke Thomsen Ingemar Turesson Annette Vangsted Ulla Vogel Anders Waage Brian A Walker Anna-Karin Wihlborg Annemiek Broyl Faith E Davies Unnur Thorsteinsdottir Christian Langer Markus Hansson Martin Kaiser Pieter Sonneveld Kari Stefansson Gareth J Morgan Hartmut Goldschmidt Kari Hemminki Björn Nilsson Richard S Houlston

Nat Commun 2016 07 1;7:12050. Epub 2016 Jul 1.

Division of Genetics and Epidemiology, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, UK.

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http://dx.doi.org/10.1038/ncomms12050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932178PMC
July 2016

ABCG2 regulates self-renewal and stem cell marker expression but not tumorigenicity or radiation resistance of glioma cells.

Authors:
Boyoung Wee Alexander Pietras Tatsuya Ozawa Elena Bazzoli Ondrej Podlaha Christophe Antczak Bengt Westermark Sven Nelander Lene Uhrbom Karin Forsberg-Nilsson Hakim Djaballah Franziska Michor Eric C Holland

Sci Rep 2016 07 26;6:25956. Epub 2016 Jul 26.

Human Biology Division, Solid Tumor and Translational Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1038/srep25956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960591PMC
July 2016

Travelling wave analysis of a mathematical model of glioblastoma growth.

Authors:
Philip Gerlee Sven Nelander

Math Biosci 2016 06 25;276:75-81. Epub 2016 Mar 25.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.mbs.2016.03.004DOI Listing
June 2016

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.

Authors:
Spyros Darmanis Caroline Julie Gallant Voichita Dana Marinescu Mia Niklasson Anna Segerman Georgios Flamourakis Simon Fredriksson Erika Assarsson Martin Lundberg Sven Nelander Bengt Westermark Ulf Landegren

Cell Rep 2016 Jan 31;14(2):380-9. Epub 2015 Dec 31.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 75108, Sweden; Science for Life Laboratory, Uppsala University, Uppsala 75108, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713867PMC
January 2016

Selective calcium sensitivity in immature glioma cancer stem cells.

Authors:
Shimei Wee Maria Niklasson Voichita Dana Marinescu Anna Segerman Linnéa Schmidt Annika Hermansson Peter Dirks Karin Forsberg-Nilsson Bengt Westermark Lene Uhrbom Sten Linnarsson Sven Nelander Michael Andäng

PLoS One 2014 22;9(12):e115698. Epub 2014 Dec 22.

Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115698PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274094PMC
December 2015

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.

Authors:
Jacomijn P Dijksterhuis Elisa Arthofer Voichita D Marinescu Sven Nelander Mathias Uhlén Frederik Pontén Jan Mulder Gunnar Schulte

Exp Cell Res 2015 Dec 25;339(2):280-8. Epub 2015 Oct 25.

Section of Receptor Biology & Signaling, Deptartment Physiology & Pharmacology, Karolinska Institutet, S17177, Stockholm, Sweden; Faculty of Science, Institute of Experimental Biology, Masaryk University, 611 37 Brno, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2015.10.022DOI Listing
December 2015

The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes.

Authors:
Yuan Xie Tobias Bergström Yiwen Jiang Patrik Johansson Voichita Dana Marinescu Nanna Lindberg Anna Segerman Grzegorz Wicher Mia Niklasson Sathishkumar Baskaran Smitha Sreedharan Isabelle Everlien Marianne Kastemar Annika Hermansson Lioudmila Elfineh Sylwia Libard Eric Charles Holland Göran Hesselager Irina Alafuzoff Bengt Westermark Sven Nelander Karin Forsberg-Nilsson Lene Uhrbom

EBioMedicine 2015 Oct 15;2(10):1351-63. Epub 2015 Aug 15.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ebiom.2015.08.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634360PMC
October 2015

Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content.

Authors:
Teresia Kling Patrik Johansson José Sanchez Voichita D Marinescu Rebecka Jörnsten Sven Nelander

Nucleic Acids Res 2015 Sep 7;43(15):e98. Epub 2015 May 7.

Department of Immunology, Genetics and Pathology (IGP) and Science for Life Laboratory, Uppsala University, Rudbecklaboratoriet, SE-751 85 Uppsala, Sweden

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http://dx.doi.org/10.1093/nar/gkv413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551906PMC
September 2015

Glioma-derived plasminogen activator inhibitor-1 (PAI-1) regulates the recruitment of LRP1 positive mast cells.

Authors:
Ananya Roy Antoine Coum Voichita D Marinescu Jelena Põlajeva Anja Smits Sven Nelander Lene Uhrbom Bengt Westermark Karin Forsberg-Nilsson Fredrik Pontén Elena Tchougounova

Oncotarget 2015 Sep;6(27):23647-61

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://www.oncotarget.com/fulltext/4640
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http://dx.doi.org/10.18632/oncotarget.4640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695142PMC
September 2015

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

Authors:
Bhairavi Swaminathan Guðmar Thorleifsson Magnus Jöud Mina Ali Ellinor Johnsson Ram Ajore Patrick Sulem Britt-Marie Halvarsson Guðmundur Eyjolfsson Vilhelmina Haraldsdottir Christina Hultman Erik Ingelsson Sigurður Y Kristinsson Anna K Kähler Stig Lenhoff Gisli Masson Ulf-Henrik Mellqvist Robert Månsson Sven Nelander Isleifur Olafsson Olof Sigurðardottir Hlif Steingrimsdóttir Annette Vangsted Ulla Vogel Anders Waage Hareth Nahi Daniel F Gudbjartsson Thorunn Rafnar Ingemar Turesson Urban Gullberg Kári Stefánsson Markus Hansson Unnur Thorsteinsdóttir Björn Nilsson

Nat Commun 2015 May 26;6:7213. Epub 2015 May 26.

1] Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, BMC B13, SE-221 84 Lund, Sweden [2] Clinical Immunology and Transfusion Medicine, Laboratory Medicine, Office of Medical Services, Akutgatan 8, SE-221 85 Lund, Sweden [3] Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ncomms8213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455110PMC
May 2015

Avoiding pitfalls in L1-regularised inference of gene networks.

Authors:
Andreas Tjärnberg Torbjörn E M Nordling Matthew Studham Sven Nelander Erik L L Sonnhammer

Mol Biosyst 2015 Jan 7;11(1):287-96. Epub 2014 Nov 7.

Stockholm Bioinformatics Centre, Science for Life Laboratory, Box 1031, 17121 Solna, Sweden.

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http://dx.doi.org/10.1039/c4mb00419aDOI Listing
January 2015

Bridging the gaps in systems biology.

Authors:
Marija Cvijovic Joachim Almquist Jonas Hagmar Stefan Hohmann Hans-Michael Kaltenbach Edda Klipp Marcus Krantz Pedro Mendes Sven Nelander Jens Nielsen Andrea Pagnani Natasa Przulj Andreas Raue Jörg Stelling Szymon Stoma Frank Tobin Judith A H Wodke Riccardo Zecchina Mats Jirstrand

Mol Genet Genomics 2014 Oct 13;289(5):727-34. Epub 2014 Apr 13.

Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Chalmers Tvärgata 3, 412 96, Göteborg, Sweden,

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http://dx.doi.org/10.1007/s00438-014-0843-3DOI Listing
October 2014

Functional association networks as priors for gene regulatory network inference.

Authors:
Matthew E Studham Andreas Tjärnberg Torbjörn E M Nordling Sven Nelander Erik L L Sonnhammer

Bioinformatics 2014 Jun;30(12):i130-8

Stockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, SwedenStockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, SwedenStockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, Sweden.

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http://dx.doi.org/10.1093/bioinformatics/btu285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058914PMC
June 2014

RETRACTED: Vulnerability of glioblastoma cells to catastrophic vacuolization and death induced by a small molecule.

Authors:
Satish Srinivas Kitambi Enrique M Toledo Dmitry Usoskin Shimei Wee Aditya Harisankar Richard Svensson Kristmundur Sigmundsson Christina Kalderén Mia Niklasson Soumi Kundu Sergi Aranda Bengt Westermark Lene Uhrbom Michael Andäng Peter Damberg Sven Nelander Ernest Arenas Per Artursson Julian Walfridsson Karin Forsberg Nilsson Lars G J Hammarström Patrik Ernfors

Cell 2014 04 20;157(2):313-328. Epub 2014 Mar 20.

Division of Molecular Neurobiology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 17177 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.02.021DOI Listing
April 2014

Searching for synergies: matrix algebraic approaches for efficient pair screening.

Authors:
Philip Gerlee Linnéa Schmidt Naser Monsefi Teresia Kling Rebecka Jörnsten Sven Nelander

PLoS One 2013 25;8(7):e68598. Epub 2013 Jul 25.

Sahlgrenska Cancer Center, University of Gothenburg, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068598PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3723843PMC
March 2014

Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.

Authors:
Linnéa Schmidt Teresia Kling Naser Monsefi Maja Olsson Caroline Hansson Sathishkumar Baskaran Bo Lundgren Ulf Martens Maria Häggblad Bengt Westermark Karin Forsberg Nilsson Lene Uhrbom Linda Karlsson-Lindahl Philip Gerlee Sven Nelander

Neuro Oncol 2013 Nov 6;15(11):1469-78. Epub 2013 Oct 6.

Corresponding Author: Sven Nelander, PhD, Immunology, Genetics and Pathology (IGP), Uppsala University; and Science for Life Laboratory, SE-751 85 Uppsala, Sweden..

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http://dx.doi.org/10.1093/neuonc/not111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813417PMC
November 2013

System-scale network modeling of cancer using EPoC.

Authors:
Tobias Abenius Rebecka Jörnsten Teresia Kling Linnéa Schmidt José Sánchez Sven Nelander

Adv Exp Med Biol 2012 ;736:617-43

Mathematical Sciences, University of Gothenburg and Chalmers University of Technology, 412 96 Gothenburg, Sweden.

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http://dx.doi.org/10.1007/978-1-4419-7210-1_37DOI Listing
January 2013

The impact of phenotypic switching on glioblastoma growth and invasion.

Authors:
Philip Gerlee Sven Nelander

PLoS Comput Biol 2012 14;8(6):e1002556. Epub 2012 Jun 14.

Sahlgrenska Cancer Center, Institute of Medicine, Göteborg, Sweden.

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http://dx.doi.org/10.1371/journal.pcbi.1002556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375261PMC
October 2012

Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma.

Authors:
Marta Persson Ywonne Andrén Christopher A Moskaluk Henry F Frierson Susanna L Cooke Philip Andrew Futreal Teresia Kling Sven Nelander Anders Nordkvist Fredrik Persson Göran Stenman

Genes Chromosomes Cancer 2012 Aug 16;51(8):805-17. Epub 2012 Apr 16.

Sahlgrenska Cancer Center, Department of Pathology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/gcc.21965DOI Listing
August 2012

Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.

Authors:
Rebecka Jörnsten Tobias Abenius Teresia Kling Linnéa Schmidt Erik Johansson Torbjörn E M Nordling Bodil Nordlander Chris Sander Peter Gennemark Keiko Funa Björn Nilsson Linda Lindahl Sven Nelander

Mol Syst Biol 2011 Apr;7:486

Mathematical Sciences, University of Gothenburg and Chalmers University of Technology, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/msb.2011.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101951PMC
April 2011

Off-target effects dominate a large-scale RNAi screen for modulators of the TGF-β pathway and reveal microRNA regulation of TGFBR2.

Authors:
Nikolaus Schultz Dina R Marenstein Dino A De Angelis Wei-Qing Wang Sven Nelander Anders Jacobsen Debora S Marks Joan Massagué Chris Sander

Silence 2011 Mar 14;2. Epub 2011 Mar 14.

Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://silencejournal.biomedcentral.com/articles/10.1186/175
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http://dx.doi.org/10.1186/1758-907X-2-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3068080PMC
March 2011

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

Authors:
Jordi Barretina Barry S Taylor Shantanu Banerji Alexis H Ramos Mariana Lagos-Quintana Penelope L Decarolis Kinjal Shah Nicholas D Socci Barbara A Weir Alan Ho Derek Y Chiang Boris Reva Craig H Mermel Gad Getz Yevgenyi Antipin Rameen Beroukhim John E Major Charles Hatton Richard Nicoletti Megan Hanna Ted Sharpe Tim J Fennell Kristian Cibulskis Robert C Onofrio Tsuyoshi Saito Neerav Shukla Christopher Lau Sven Nelander Serena J Silver Carrie Sougnez Agnes Viale Wendy Winckler Robert G Maki Levi A Garraway Alex Lash Heidi Greulich David E Root William R Sellers Gary K Schwartz Cristina R Antonescu Eric S Lander Harold E Varmus Marc Ladanyi Chris Sander Matthew Meyerson Samuel Singer

Nat Genet 2010 Aug 4;42(8):715-21. Epub 2010 Jul 4.

Department of Medical Oncology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911503PMC
August 2010

Models from experiments: combinatorial drug perturbations of cancer cells.

Authors:
Sven Nelander Weiqing Wang Björn Nilsson Qing-Bai She Christine Pratilas Neal Rosen Peter Gennemark Chris Sander

Mol Syst Biol 2008 2;4:216. Epub 2008 Sep 2.

Computational Biology center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/msb.2008.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2564730PMC
November 2008

Do two mutually exclusive gene modules define the phenotypic diversity of mammalian smooth muscle?

Authors:
Erik Larsson Sean E McLean Robert P Mecham Per Lindahl Sven Nelander

Mol Genet Genomics 2008 Aug 29;280(2):127-37. Epub 2008 May 29.

Institution for Medicine, Wallenberg Laboratory, Sahlgrenska University Hospital, Bruna stråket 16, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00438-008-0349-yDOI Listing
August 2008

Smooth muscle expression of lipoma preferred partner is mediated by an alternative intronic promoter that is regulated by serum response factor/myocardin.

Authors:
Marleen M R Petit Henrik Lindskog Erik Larsson Per Wasteson Elisabeth Athley Silke Breuer Meike Angstenberger David Hertfelder Erney Mattsson Alfred Nordheim Sven Nelander Per Lindahl

Circ Res 2008 Jul 29;103(1):61-9. Epub 2008 May 29.

Wallenberg Laboratory, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://dx.doi.org/10.1161/CIRCRESAHA.108.177436DOI Listing
July 2008

An improved method for detecting and delineating genomic regions with altered gene expression in cancer.

Authors:
Björn Nilsson Mikael Johansson Anders Heyden Sven Nelander Thoas Fioretos

Genome Biol 2008 Jan 21;9(1):R13. Epub 2008 Jan 21.

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1186/gb-2008-9-1-r13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2395254PMC
January 2008

Threshold-free high-power methods for the ontological analysis of genome-wide gene-expression studies.

Authors:
Björn Nilsson Petra Håkansson Mikael Johansson Sven Nelander Thoas Fioretos

Genome Biol 2007 ;8(5):R74

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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http://dx.doi.org/10.1186/gb-2007-8-5-r74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1929143PMC
September 2007

DNA microarray study on gene expression profiles in co-cultured endothelial and smooth muscle cells in response to 4- and 24-h shear stress.

Authors:
Sepideh Heydarkhan-Hagvall Shu Chien Sven Nelander Yi-Chen Li Suli Yuan Jianmin Lao Jason H Haga Ian Lian Phu Nguyen Bo Risberg Yi-Shuan Li

Mol Cell Biochem 2006 Jan;281(1-2):1-15

Wallenberg Laboratory for Vascular Research, Department of Surgery and Vascular Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.

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http://link.springer.com/10.1007/s11010-006-0168-6
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http://dx.doi.org/10.1007/s11010-006-0168-6DOI Listing
January 2006

Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics.

Authors:
Peter Akerblad Robert Månsson Anna Lagergren Simonetta Westerlund Barbro Basta Ulrika Lind Anders Thelin Ramiro Gisler David Liberg Sven Nelander Krister Bamberg Mikael Sigvardsson

Physiol Genomics 2005 Oct 16;23(2):206-16. Epub 2005 Aug 16.

Department of Molecular Pharmacology, AstraZeneca Research and Development, Molndal, Sweden.

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http://dx.doi.org/10.1152/physiolgenomics.00015.2005DOI Listing
October 2005

Neural cell adhesion molecule-deficient beta-cell tumorigenesis results in diminished extracellular matrix molecule expression and tumour cell-matrix adhesion.

Authors:
Joakim Håkansson Xiaojie Xian Liqun He Anders Ståhlberg Sven Nelander Tore Samuelsson Mikael Kubista Henrik Semb

Tumour Biol 2005 Mar-Apr;26(2):103-12

Department of Medical Biochemistry, Göteborg University, Sweden.

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http://dx.doi.org/10.1159/000085817DOI Listing
June 2005

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals.

Authors:
Sven Nelander Erik Larsson Erik Kristiansson Robert Månsson Olle Nerman Mikael Sigvardsson Petter Mostad Per Lindahl

BMC Genomics 2005 May 9;6:68. Epub 2005 May 9.

Department of medical and physiological biochemistry, Sahlgrenska Academy, Box 440, SE-405 30 Göteborg, Sweden.

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http://dx.doi.org/10.1186/1471-2164-6-68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1134656PMC
May 2005

Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family.

Authors:
Rui-Dong Duan Tomas Bergman Ning Xu Jun Wu Yajun Cheng Jianxin Duan Sven Nelander Carina Palmberg Ake Nilsson

J Biol Chem 2003 Oct 28;278(40):38528-36. Epub 2003 Jul 28.

Gastroenterology Laboratory, Biomedical Center, B11, Lund University, S-221 84 Lund, Sweden.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M305437200
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http://dx.doi.org/10.1074/jbc.M305437200DOI Listing
October 2003

Prediction of cell type-specific gene modules: identification and initial characterization of a core set of smooth muscle-specific genes.

Authors:
Sven Nelander Petter Mostad Per Lindahl

Genome Res 2003 Aug 17;13(8):1838-54. Epub 2003 Jul 17.

Department of Medical Biochemistry, Göteborg University, SE 40530 Gothenburg, Sweden.

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http://www.genome.org/cgi/doi/10.1101/gr.1197303
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http://dx.doi.org/10.1101/gr.1197303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC403775PMC
August 2003