Sven Nelander

Sven Nelander

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Sven Nelander

Sven Nelander

Publications by authors named "Sven Nelander"

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48Publications

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Image-Based Detection of Patient-Specific Drug-Induced Cell-Cycle Effects in Glioblastoma.

SLAS Discov 2018 Dec 3;23(10):1030-1039. Epub 2018 Aug 3.

2 Centre for Image Analysis, Uppsala University, Uppsala, Sweden.

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December 2018

Glioblastoma Cell Malignancy and Drug Sensitivity Are Affected by the Cell of Origin.

Cell Rep 2017 01;18(4):977-990

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, 75185 Uppsala, Sweden. Electronic address:

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January 2017

Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma.

EBioMedicine 2016 Oct 18;12:72-85. Epub 2016 Sep 18.

Dept of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Rudbecklaboratoriet, SE-751 85 Uppsala, Sweden. Electronic address:

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October 2016

High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer.

BMC Cancer 2016 Aug 25;16(1):683. Epub 2016 Aug 25.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarskjöldsv 20, Uppsala, 751 85, Sweden.

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August 2016

Origin of the U87MG glioma cell line: Good news and bad news.

Sci Transl Med 2016 08;8(354):354re3

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, SE-751 85 Uppsala, Sweden.

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August 2016

Travelling wave analysis of a mathematical model of glioblastoma growth.

Math Biosci 2016 06 25;276:75-81. Epub 2016 Mar 25.

Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85 Uppsala, Sweden.

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June 2016

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.

Cell Rep 2016 Jan 31;14(2):380-9. Epub 2015 Dec 31.

Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala 75108, Sweden; Science for Life Laboratory, Uppsala University, Uppsala 75108, Sweden. Electronic address:

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January 2016

High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.

Exp Cell Res 2015 Dec 25;339(2):280-8. Epub 2015 Oct 25.

Section of Receptor Biology & Signaling, Deptartment Physiology & Pharmacology, Karolinska Institutet, S17177, Stockholm, Sweden; Faculty of Science, Institute of Experimental Biology, Masaryk University, 611 37 Brno, Czech Republic. Electronic address:

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December 2015

Efficient exploration of pan-cancer networks by generalized covariance selection and interactive web content.

Nucleic Acids Res 2015 Sep 7;43(15):e98. Epub 2015 May 7.

Department of Immunology, Genetics and Pathology (IGP) and Science for Life Laboratory, Uppsala University, Rudbecklaboratoriet, SE-751 85 Uppsala, Sweden

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September 2015

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

Nat Commun 2015 May 26;6:7213. Epub 2015 May 26.

1] Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, BMC B13, SE-221 84 Lund, Sweden [2] Clinical Immunology and Transfusion Medicine, Laboratory Medicine, Office of Medical Services, Akutgatan 8, SE-221 85 Lund, Sweden [3] Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

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May 2015

Avoiding pitfalls in L1-regularised inference of gene networks.

Mol Biosyst 2015 Jan 7;11(1):287-96. Epub 2014 Nov 7.

Stockholm Bioinformatics Centre, Science for Life Laboratory, Box 1031, 17121 Solna, Sweden.

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January 2015

Bridging the gaps in systems biology.

Mol Genet Genomics 2014 Oct 13;289(5):727-34. Epub 2014 Apr 13.

Department of Mathematical Sciences, Chalmers University of Technology and University of Gothenburg, Chalmers Tvärgata 3, 412 96, Göteborg, Sweden,

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October 2014

Functional association networks as priors for gene regulatory network inference.

Bioinformatics 2014 Jun;30(12):i130-8

Stockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, SwedenStockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, SwedenStockholm Bioinformatics Centre, Science for Life Laboratory, SE-171 65 Solna, Sweden, Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden, Department of Immunology, Genetics and Pathology, Uppsala University, Rudbeck Laboratory, SE-751 05 Uppsala, Sweden and Swedish eScience Research Center, SE-100 44 Stockholm, Sweden.

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June 2014

Searching for synergies: matrix algebraic approaches for efficient pair screening.

PLoS One 2013 25;8(7):e68598. Epub 2013 Jul 25.

Sahlgrenska Cancer Center, University of Gothenburg, Gothenburg, Sweden.

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March 2014

Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.

Neuro Oncol 2013 Nov 6;15(11):1469-78. Epub 2013 Oct 6.

Corresponding Author: Sven Nelander, PhD, Immunology, Genetics and Pathology (IGP), Uppsala University; and Science for Life Laboratory, SE-751 85 Uppsala, Sweden..

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November 2013

System-scale network modeling of cancer using EPoC.

Adv Exp Med Biol 2012 ;736:617-43

Mathematical Sciences, University of Gothenburg and Chalmers University of Technology, 412 96 Gothenburg, Sweden.

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January 2013

The impact of phenotypic switching on glioblastoma growth and invasion.

PLoS Comput Biol 2012 14;8(6):e1002556. Epub 2012 Jun 14.

Sahlgrenska Cancer Center, Institute of Medicine, Göteborg, Sweden.

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October 2012

Clinically significant copy number alterations and complex rearrangements of MYB and NFIB in head and neck adenoid cystic carcinoma.

Genes Chromosomes Cancer 2012 Aug 16;51(8):805-17. Epub 2012 Apr 16.

Sahlgrenska Cancer Center, Department of Pathology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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August 2012

Models from experiments: combinatorial drug perturbations of cancer cells.

Mol Syst Biol 2008 2;4:216. Epub 2008 Sep 2.

Computational Biology center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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November 2008

Do two mutually exclusive gene modules define the phenotypic diversity of mammalian smooth muscle?

Mol Genet Genomics 2008 Aug 29;280(2):127-37. Epub 2008 May 29.

Institution for Medicine, Wallenberg Laboratory, Sahlgrenska University Hospital, Bruna stråket 16, Gothenburg, Sweden.

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August 2008

An improved method for detecting and delineating genomic regions with altered gene expression in cancer.

Genome Biol 2008 Jan 21;9(1):R13. Epub 2008 Jan 21.

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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January 2008

Threshold-free high-power methods for the ontological analysis of genome-wide gene-expression studies.

Genome Biol 2007 ;8(5):R74

Department of Clinical Genetics, Lund University Hospital, SE-221 85 Lund, Sweden.

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September 2007

DNA microarray study on gene expression profiles in co-cultured endothelial and smooth muscle cells in response to 4- and 24-h shear stress.

Mol Cell Biochem 2006 Jan;281(1-2):1-15

Wallenberg Laboratory for Vascular Research, Department of Surgery and Vascular Surgery, Sahlgrenska University Hospital, Göteborg, Sweden.

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January 2006

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals.

BMC Genomics 2005 May 9;6:68. Epub 2005 May 9.

Department of medical and physiological biochemistry, Sahlgrenska Academy, Box 440, SE-405 30 Göteborg, Sweden.

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May 2005

Identification of human intestinal alkaline sphingomyelinase as a novel ecto-enzyme related to the nucleotide phosphodiesterase family.

J Biol Chem 2003 Oct 28;278(40):38528-36. Epub 2003 Jul 28.

Gastroenterology Laboratory, Biomedical Center, B11, Lund University, S-221 84 Lund, Sweden.

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October 2003

Prediction of cell type-specific gene modules: identification and initial characterization of a core set of smooth muscle-specific genes.

Genome Res 2003 Aug 17;13(8):1838-54. Epub 2003 Jul 17.

Department of Medical Biochemistry, Göteborg University, SE 40530 Gothenburg, Sweden.

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August 2003