Sven Heinz

Sven Heinz

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Sven Heinz

Sven Heinz

Publications by authors named "Sven Heinz"

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Genomic Decoding of Neuronal Depolarization by Stimulus-Specific NPAS4 Heterodimers.

Cell 2019 Oct;179(2):373-391.e27

Division of Biological Sciences, Section of Neurobiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0634, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674193101
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http://dx.doi.org/10.1016/j.cell.2019.09.004DOI Listing
October 2019

Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.

Proc Natl Acad Sci U S A 2019 Aug 1;116(34):16933-16942. Epub 2019 Aug 1.

Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA 92037;

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http://dx.doi.org/10.1073/pnas.1903059116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708373PMC
August 2019

Generating a Three-Dimensional Genome from with Hi-C.

Cold Spring Harb Protoc 2019 May 1;2019(5):pdb.prot098343. Epub 2019 May 1.

Department of Medicine, University of California, San Diego, San Diego, California 92093

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http://dx.doi.org/10.1101/pdb.prot098343DOI Listing
May 2019

Transcription Elongation Can Affect Genome 3D Structure.

Cell 2018 09 23;174(6):1522-1536.e22. Epub 2018 Aug 23.

Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0640, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183097
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http://dx.doi.org/10.1016/j.cell.2018.07.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130916PMC
September 2018

Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer.

Mol Cell 2018 06 31;70(5):842-853.e7. Epub 2018 May 31.

Laboratory of Genetics, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545586PMC
June 2018

Genome evolution in the allotetraploid frog Xenopus laevis.

Nature 2016 10;538(7625):336-343

University of California, Berkeley, Department of Molecular and Cell Biology and Center for Integrative Genomics, Life Sciences Addition #3200, Berkeley, California 94720-3200, USA.

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http://dx.doi.org/10.1038/nature19840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313049PMC
October 2016

Perspectives on Unidirectional versus Divergent Transcription.

Mol Cell 2015 Nov;60(3):348-9

Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany; Department of Biology, Humboldt University, 10115 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643650PMC
November 2015

Exploiting genomics and natural genetic variation to decode macrophage enhancers.

Trends Immunol 2015 Sep 19;36(9):507-18. Epub 2015 Aug 19.

Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0651, USA. Electronic address:

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http://dx.doi.org/10.1016/j.it.2015.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548828PMC
September 2015

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis.

Nat Immunol 2015 May 30;16(5):485-94. Epub 2015 Mar 30.

1] Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA. [2] Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4406851PMC
May 2015

The selection and function of cell type-specific enhancers.

Nat Rev Mol Cell Biol 2015 Mar 4;16(3):144-54. Epub 2015 Feb 4.

1] Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, San Diego, California 92093, USA. [2] Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, San Diego, California 92093, USA.

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http://dx.doi.org/10.1038/nrm3949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517609PMC
March 2015

Human promoters are intrinsically directional.

Mol Cell 2015 Feb 29;57(4):674-684. Epub 2015 Jan 29.

Berlin Institute for Medical Systems Biology, Max Delbrück Center for Molecular Medicine, 13125 Berlin, Germany; Department of Biology, Humboldt University, 10115 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2014.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336624PMC
February 2015

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization.

Nucleic Acids Res 2014 Nov 28;42(20):12570-84. Epub 2014 Oct 28.

A.I. Virtanen Institute for Molecular Sciences, Department of Biotechnology and Molecular Medicine, University of Eastern Finland, PO Box 1627, 70211 Kuopio, Finland Science Service Center and Gene Therapy Unit, Kuopio University Hospital, Finland.

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http://dx.doi.org/10.1093/nar/gku1036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227755PMC
November 2014

Roles of lineage-determining transcription factors in establishing open chromatin: lessons from high-throughput studies.

Curr Top Microbiol Immunol 2012 ;356:1-15

Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

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http://link.springer.com/10.1007/82_2011_142
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http://dx.doi.org/10.1007/82_2011_142DOI Listing
April 2012

Research resource: Comparative nuclear receptor atlas: basal and activated peritoneal B-1 and B-2 cells.

Mol Endocrinol 2011 Mar 27;25(3):529-45. Epub 2011 Jan 27.

Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1210/me.2010-0384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045740PMC
March 2011

Serum response factor utilizes distinct promoter- and enhancer-based mechanisms to regulate cytoskeletal gene expression in macrophages.

Mol Cell Biol 2011 Feb 6;31(4):861-75. Epub 2010 Dec 6.

University of California, San Diego, Department of Cellular and Molecular Medicine, La Jolla, CA 92093-0651, USA.

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http://dx.doi.org/10.1128/MCB.00836-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3028656PMC
February 2011

FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages.

EMBO J 2010 Dec 2;29(24):4223-36. Epub 2010 Nov 2.

Division of Endocrinology-Metabolism, Department of Medicine, University of California, San Diego, La Jolla, CA 92093-0673, USA.

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http://emboj.embopress.org/cgi/doi/10.1038/emboj.2010.268
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http://dx.doi.org/10.1038/emboj.2010.268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018786PMC
December 2010

Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels.

Genome Biol 2010 18;11(6):R63. Epub 2010 Jun 18.

Department of Hematology, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany.

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http://dx.doi.org/10.1186/gb-2010-11-6-r63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911111PMC
November 2010

Species-specific regulation of Toll-like receptor 3 genes in men and mice.

J Biol Chem 2003 Jun 2;278(24):21502-9. Epub 2003 Apr 2.

Department of Hematology and Oncology, University of Regensburg, 93042 Regensburg, Germany.

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http://dx.doi.org/10.1074/jbc.M301476200DOI Listing
June 2003