Publications by authors named "Sven Geissler"

43Publications

Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification.

Sci Rep 2020 04 6;10(1):5951. Epub 2020 Apr 6.

Berlin Institute of Health Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1038/s41598-020-62568-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136202PMC
April 2020

Adult Osteosclerotic Metaphyseal Dysplasia With Progressive Osteonecrosis of the Jaws and Abnormal Bone Resorption Pattern Due to a LRRK1 Splice Site Mutation.

J Bone Miner Res 2020 Jul 19;35(7):1322-1332. Epub 2020 Mar 19.

Institut für Medizinische Genetik und Humangenetik, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1002/jbmr.3995DOI Listing
July 2020

Evaluation of 3D Printed Gelatin-Based Scaffolds with Varying Pore Size for MSC-Based Adipose Tissue Engineering.

Macromol Biosci 2020 04 20;20(4):e1900364. Epub 2020 Feb 20.

Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1002/mabi.201900364DOI Listing
April 2020

Editorial comment: variables affecting the presence of mesenchymal stromal cells in the peripheral blood and their relationship with apheresis product.

Br J Haematol 2020 May 10;189(4):593-596. Epub 2020 Feb 10.

BIH Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/bjh.16389DOI Listing
May 2020

Diagnosis of Metal Hypersensitivity in Total Knee Arthroplasty: A Case Report.

Front Immunol 2019 27;10:2758. Epub 2019 Nov 27.

Berlin Institute of Health Center for Regenerative Therapies, Berlin, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890602PMC
November 2019

Preclinical Toxicity Evaluation of Clinical Grade Placenta-Derived Decidua Stromal Cells.

Front Immunol 2019 19;10:2685. Epub 2019 Nov 19.

Translational Cell Therapy Research (TCR), Department of Clinical Science Intervention and Technology (CLINTEC), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2019.02685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6877599PMC
November 2019

Niche-mimicking interactions in peptide-functionalized 3D hydrogels amplify mesenchymal stromal cell paracrine effects.

Biomaterials 2020 02 20;230:119639. Epub 2019 Nov 20.

Julius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany; Charité Universitätsmedizin Berlin, Berlin Institute of Health Center for Regenerative Therapies, Louisa-Karsch-Str. 2, 10178, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2019.119639DOI Listing
February 2020

The Allergic Bone Marrow? The Immuno-Capacity of the Human Bone Marrow in Context of Metal-Associated Hypersensitivity Reactions.

Front Immunol 2019 18;10:2232. Epub 2019 Sep 18.

Julius Wolff Institute, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Berlin Institute of Health, Humboldt-Universität zu Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759684PMC
September 2019

Oxidized alginate beads for tunable release of osteogenically potent mesenchymal stromal cells.

Mater Sci Eng C Mater Biol Appl 2019 Nov 22;104:109911. Epub 2019 Jun 22.

Berlin-Brandenburg Center for Regenerative Therapies, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Department of Bioengineering, University of Pennsylvania, 210 South 33rd Street, Philadelphia 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msec.2019.109911DOI Listing
November 2019

Individual Effector/Regulator T Cell Ratios Impact Bone Regeneration.

Front Immunol 2019 16;10:1954. Epub 2019 Aug 16.

Julius Wolff Institut and Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.01954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706871PMC
October 2020

Cell therapy to improve regeneration of skeletal muscle injuries.

J Cachexia Sarcopenia Muscle 2019 06 6;10(3):501-516. Epub 2019 Mar 6.

Julius Wolff Institute, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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http://dx.doi.org/10.1002/jcsm.12416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596399PMC
June 2019

Intravascular Mesenchymal Stromal/Stem Cell Therapy Product Diversification: Time for New Clinical Guidelines.

Trends Mol Med 2019 02 30;25(2):149-163. Epub 2019 Jan 30.

Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin (FUB), Humboldt-Universität zu Berlin (HUB), and Berlin Institute of Health (BIH), Berlin, Germany; Department of Nephrology and Internal Intensive Care Medicine, Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin (FUB), Humboldt-Universität zu Berlin (HUB), and Berlin Institute of Health (BIH), Berlin, Germany; Berlin Center for Advanced Therapies (BECAT), Charité Universitätsmedizin Berlin, corporate member of Freie Universität Berlin (FUB), Humboldt-Universität zu Berlin (HUB), and Berlin Institute of Health (BIH), Berlin, Germany; Equal contribution senior authorship.

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http://dx.doi.org/10.1016/j.molmed.2018.12.006DOI Listing
February 2019

Dosage and composition of bioactive glasses differentially regulate angiogenic and osteogenic response of human MSCs.

J Biomed Mater Res A 2018 11 3;106(11):2827-2837. Epub 2018 Oct 3.

Julius Wolff Institute, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1002/jbm.a.36470DOI Listing
November 2018

Loss of murine Gfi1 causes neutropenia and induces osteoporosis depending on the pathogen load and systemic inflammation.

PLoS One 2018 7;13(6):e0198510. Epub 2018 Jun 7.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute for Medical Genetics and Human Genetics, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991660PMC
December 2018

Immunology Guides Skeletal Muscle Regeneration.

Int J Mol Sci 2018 Mar 13;19(3). Epub 2018 Mar 13.

Julius Wolff Institut, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.

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http://dx.doi.org/10.3390/ijms19030835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877696PMC
March 2018

Tumour necrosis factor-alpha in uraemic serum promotes osteoblastic transition and calcification of vascular smooth muscle cells via extracellular signal-regulated kinases and activator protein 1/c-FOS-mediated induction of interleukin 6 expression.

Nephrol Dial Transplant 2018 04;33(4):574-585

Clinic for Nephrology and Critical Care Medicine, Charite-Universitatsmedizin Berlin, corporate member of Freie Universitat Berlin, Humboldt-Universitat zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.

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http://dx.doi.org/10.1093/ndt/gfx316DOI Listing
April 2018

Multi-elemental nanoparticle exposure after tantalum component failure in hip arthroplasty: In-depth analysis of a single case.

Nanomedicine 2017 Nov 16;13(8):2415-2423. Epub 2017 Aug 16.

Center for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.nano.2017.08.004DOI Listing
November 2017

Biomaterials that promote cell-cell interactions enhance the paracrine function of MSCs.

Biomaterials 2017 Sep 18;140:103-114. Epub 2017 Jun 18.

Julius Wolff Institute, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies & Berlin-Brandenburg School for Regenerative Therapies, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2017.06.019DOI Listing
September 2017

CD31+ Cells From Peripheral Blood Facilitate Bone Regeneration in Biologically Impaired Conditions Through Combined Effects on Immunomodulation and Angiogenesis.

J Bone Miner Res 2017 May 1;32(5):902-912. Epub 2017 Mar 1.

Julius Wolff Institute (JWI) and Center for Musculoskeletal Surgery, Charité - University Medicine Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/jbmr.3062DOI Listing
May 2017

Cryopreserved or Fresh Mesenchymal Stromal Cells: Only a Matter of Taste or Key to Unleash the Full Clinical Potential of MSC Therapy?

Adv Exp Med Biol 2016 ;951:77-98

Therapeutic Immunology (TIM), Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/978-3-319-45457-3_7DOI Listing
September 2017

Influence of Donor Age and Stimulation Intensity on Osteogenic Differentiation of Rat Mesenchymal Stromal Cells in Response to Focused Low-Intensity Pulsed Ultrasound.

Ultrasound Med Biol 2016 12 24;42(12):2965-2974. Epub 2016 Sep 24.

Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ultrasmedbio.2016.08.012DOI Listing
December 2016

Synthetic niche to modulate regenerative potential of MSCs and enhance skeletal muscle regeneration.

Biomaterials 2016 08 10;99:95-108. Epub 2016 May 10.

Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies & Berlin-Brandenburg School for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Center for Musculoskeletal Surgery, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.05.009DOI Listing
August 2016

Generation of an iPS cell line from bone marrow derived mesenchymal stromal cells from an elderly patient.

Stem Cell Res 2015 Nov 9;15(3):565-8. Epub 2015 Oct 9.

Institute for Stem Cell Research and Regenerative Medicine, Heinrich Heine University Duesseldorf, Moorenstr. 5, 40225 Duesseldorf, Germany; Max Planck Institut für Molekulare Genetik, Ihnestraße 63-73, 14195 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2015.10.003DOI Listing
November 2015

Do Matrix Metalloproteases and Tissue Inhibitors of Metalloproteases in Tenocytes of the Rotator Cuff Differ with Varying Donor Characteristics?

Int J Mol Sci 2015 Jun 9;16(6):13141-57. Epub 2015 Jun 9.

Julius Wolff Institute, Center for Musculoskeletal Surgery, Charité-Universitaetsmedizin Berlin, 13353 Berlin, Germany.

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http://dx.doi.org/10.3390/ijms160613141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490489PMC
June 2015

Biomaterials based strategies for skeletal muscle tissue engineering: existing technologies and future trends.

Biomaterials 2015 21;53:502-21. Epub 2015 Mar 21.

Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Germany; Berlin-Brandenburg School for Regenerative Therapies, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.02.110DOI Listing
January 2016

Interaction of age and mechanical stability on bone defect healing: an early transcriptional analysis of fracture hematoma in rat.

PLoS One 2014 4;9(9):e106462. Epub 2014 Sep 4.

Julius Wolff Institute, Charité - Universitätsmedizin, Berlin, Germany; Klinik für Orthopädie, Centrum für Muskuloskeletale Chirurgie, Charité - Universitätsmedizin, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106462PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154721PMC
May 2015

MALDI imaging mass spectrometry: discrimination of pathophysiological regions in traumatized skeletal muscle by characteristic peptide signatures.

Proteomics 2014 Oct 21;14(20):2249-60. Epub 2014 Aug 21.

Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany; Core Unit Proteomics, Berlin-Brandenburg Center for Regenerative Therapies, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/pmic.201400088DOI Listing
October 2014

Qualifying stem cell sources: how to overcome potential pitfalls in regenerative medicine?

J Tissue Eng Regen Med 2016 Jan 12;10(1):3-10. Epub 2014 Jun 12.

Julius Wolff Institute and Centre for Musculoskeletal Surgery, Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1002/term.1923DOI Listing
January 2016

Increased BMP expression in arthrofibrosis after TKA.

Knee Surg Sports Traumatol Arthrosc 2012 Sep 17;20(9):1803-8. Epub 2011 Nov 17.

Orthopaedic Department, Center for Musculoskeletal Surgery, Charité-University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1007/s00167-011-1774-8DOI Listing
September 2012

Insights into mesenchymal stem cell aging: involvement of antioxidant defense and actin cytoskeleton.

Stem Cells 2009 Jun;27(6):1288-97

Julius Wolff Institute and Center for Musculoskeletal Surgery Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/stem.49DOI Listing
June 2009

Matrix metalloprotease activity is an essential link between mechanical stimulus and mesenchymal stem cell behavior.

Stem Cells 2007 Aug 10;25(8):1985-94. Epub 2007 May 10.

Musculoskeletal Research Center Berlin, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany.

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http://dx.doi.org/10.1634/stemcells.2006-0676DOI Listing
August 2007

Impact of age on the short-term postoperative outcome of patients undergoing surgery for colorectal carcinoma.

Int J Colorectal Dis 2002 May;17(3):177-84

Institute for Quality Management in Operative Medicine, Department of Surgery, Otto von Guericke University, Magdeburg, Germany.

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http://dx.doi.org/10.1007/s003840100344DOI Listing
May 2002