Suzanne J Brown

Suzanne J Brown

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Suzanne J Brown

Suzanne J Brown

Publications by authors named "Suzanne J Brown"

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Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts.

J Bone Miner Res 2018 06 24;33(6):1044-1051. Epub 2018 Mar 24.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Australia.

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http://dx.doi.org/10.1002/jbmr.3412DOI Listing
June 2018

How many cases of disease in a pedigree imply familial disease?

Ann Hum Genet 2018 03 23;82(2):109-113. Epub 2017 Oct 23.

Department of Endocrinology & Diabetes, Sir Charles Gairdner Hospital, Nedlands, Australia.

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http://dx.doi.org/10.1111/ahg.12222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813157PMC
March 2018

The endoplasmic reticulum-associated protein, OS-9, behaves as a lectin in targeting the immature calcium-sensing receptor.

J Cell Physiol 2018 Jan 5;233(1):38-56. Epub 2017 Jun 5.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.

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http://dx.doi.org/10.1002/jcp.25957DOI Listing
January 2018

Rationalizing Thyroid Function Testing: Which TSH Cutoffs Are Optimal for Testing Free T4?

J Clin Endocrinol Metab 2017 11;102(11):4235-4241

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2017-01322DOI Listing
November 2017

Lower TSH and higher free thyroxine predict incidence of prostate but not breast, colorectal or lung cancer.

Eur J Endocrinol 2017 Oct 6;177(4):297-308. Epub 2017 Jul 6.

School of Medicine, The University of Western Australia, Crawley, Western Australia, Australia.

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http://dx.doi.org/10.1530/EJE-17-0197DOI Listing
October 2017

The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

Clin Endocrinol (Oxf) 2016 Nov 19;85(5):789-796. Epub 2016 Jun 19.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.

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http://dx.doi.org/10.1111/cen.13107DOI Listing
November 2016

Quantifying the intraindividual variation of antimüllerian hormone in the ovarian cycle.

Fertil Steril 2016 Oct 25;106(5):1230-1237. Epub 2016 Jun 25.

Western Diagnostic Pathology, Myaree, Western Australia, Australia.

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http://dx.doi.org/10.1016/j.fertnstert.2016.06.009DOI Listing
October 2016

Polycystic ovary syndrome in type 2 diabetes: does it predict a more severe phenotype?

Fertil Steril 2016 Oct 25;106(5):1258-1263. Epub 2016 Jul 25.

School of Medicine and Pharmacology, University of Western Australia, Nedlands, Western Australia, Australia; Keogh Institute for Medical Research, Nedlands, Western Australia, Australia; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.fertnstert.2016.06.040DOI Listing
October 2016

Reconciling the Log-Linear and Non-Log-Linear Nature of the TSH-Free T4 Relationship: Intra-Individual Analysis of a Large Population.

J Clin Endocrinol Metab 2016 Mar 6;101(3):1151-8. Epub 2016 Jan 6.

Department of Endocrinology and Diabetes (K.M.R., S.J.B., J.P.W.), Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia; Department of Clinical Biochemistry (K.M.R., N.C.H., R.W.), PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia; Western Diagnostic Pathology (N.C.H.), Myaree, Western Australia 6154, Australia; School of Pathology and Laboratory Medicine, The University of Western Australia (N.C.H.), Crawley, Western Australia 6009, Australia; and School of Medicine and Pharmacology (J.P.W.), The University of Western Australia, Crawley, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2015-4011DOI Listing
March 2016

Brief report: Does PTH increase with age, independent of 25-hydroxyvitamin D, phosphate, renal function, and ionized calcium?

J Clin Endocrinol Metab 2015 May 9;100(5):2131-4. Epub 2015 Mar 9.

Department of Clinical Biochemistry (S.J.C., R.W., N.C.H.), PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia; Department of Endocrinology and Diabetes (S.J.C., J.P.W., S.J.B.), Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia; and School of Medicine and Pharmacology (J.P.W.) and School of Pathology and Laboratory Medicine (N.C.H.), The University of Western Australia, Crawley, Western Australia 6009, Australia.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-4370DOI Listing
May 2015

Does the thyroid-stimulating hormone measured concurrently with first trimester biochemical screening tests predict adverse pregnancy outcomes occurring after 20 weeks gestation?

J Clin Endocrinol Metab 2014 Dec;99(12):E2668-72

Department of Endocrinology and Diabetes (G.S.Y.O., S.J.B., E.M.L., J.P.W.) and Department of General Medicine (G.S.Y.O.), Sir Charles Gairdner Hospital, Nedlands 6009 Australia; Department of Clinical Biochemistry (N.C.H., E.M.L.), PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands 6009 Australia; and School of Medicine and Pharmacology (J.P.W.), The University of Western Australia, Crawley 6009 Australia.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2014-1918DOI Listing
December 2014

How good is a morning cortisol in predicting an adequate response to intramuscular synacthen stimulation?

Clin Endocrinol (Oxf) 2014 Jul 17;81(1):19-24. Epub 2013 Dec 17.

The Alfred Hospital, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/cen.12373DOI Listing
July 2014

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium.

Authors:
Alireza Moayyeri Yi-Hsiang Hsu David Karasik Karol Estrada Su-Mei Xiao Carrie Nielson Priya Srikanth Sylvie Giroux Scott G Wilson Hou-Feng Zheng Albert V Smith Stephen R Pye Paul J Leo Alexander Teumer Joo-Yeon Hwang Claes Ohlsson Fiona McGuigan Ryan L Minster Caroline Hayward José M Olmos Leo-Pekka Lyytikäinen Joshua R Lewis Karin M A Swart Laura Masi Chris Oldmeadow Elizabeth G Holliday Sulin Cheng Natasja M van Schoor Nicholas C Harvey Marcin Kruk Fabiola del Greco M Wilmar Igl Olivia Trummer Efi Grigoriou Robert Luben Ching-Ti Liu Yanhua Zhou Ling Oei Carolina Medina-Gomez Joseph Zmuda Greg Tranah Suzanne J Brown Frances M Williams Nicole Soranzo Johanna Jakobsdottir Kristin Siggeirsdottir Kate L Holliday Anke Hannemann Min Jin Go Melissa Garcia Ozren Polasek Marika Laaksonen Kun Zhu Anke W Enneman Mark McEvoy Roseanne Peel Pak Chung Sham Maciej Jaworski Åsa Johansson Andrew A Hicks Pawel Pludowski Rodney Scott Rosalie A M Dhonukshe-Rutten Nathalie van der Velde Mika Kähönen Jorma S Viikari Harri Sievänen Olli T Raitakari Jesús González-Macías Jose L Hernández Dan Mellström Osten Ljunggren Yoon Shin Cho Uwe Völker Matthias Nauck Georg Homuth Henry Völzke Robin Haring Matthew A Brown Eugene McCloskey Geoffrey C Nicholson Richard Eastell John A Eisman Graeme Jones Ian R Reid Elaine M Dennison John Wark Steven Boonen Dirk Vanderschueren Frederick C W Wu Thor Aspelund J Brent Richards Doug Bauer Albert Hofman Kay-Tee Khaw George Dedoussis Barbara Obermayer-Pietsch Ulf Gyllensten Peter P Pramstaller Roman S Lorenc Cyrus Cooper Annie Wai Chee Kung Paul Lips Markku Alen John Attia Maria Luisa Brandi Lisette C P G M de Groot Terho Lehtimäki José A Riancho Harry Campbell Yongmei Liu Tamara B Harris Kristina Akesson Magnus Karlsson Jong-Young Lee Henri Wallaschofski Emma L Duncan Terence W O'Neill Vilmundur Gudnason Timothy D Spector François Rousseau Eric Orwoll Steven R Cummings Nick J Wareham Fernando Rivadeneira Andre G Uitterlinden Richard L Prince Douglas P Kiel Jonathan Reeve Stephen K Kaptoge

Hum Mol Genet 2014 Jun 14;23(11):3054-68. Epub 2014 Jan 14.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/ddt675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038791PMC
June 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Reply of the authors.

Fertil Steril 2013 Jul 10;100(1):e2. Epub 2013 May 10.

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http://dx.doi.org/10.1016/j.fertnstert.2013.04.012DOI Listing
July 2013

The relationship between TSH and free T₄ in a large population is complex and nonlinear and differs by age and sex.

J Clin Endocrinol Metab 2013 Jul 13;98(7):2936-43. Epub 2013 May 13.

Department of Clinical Biochemistry, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6009, Australia.

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http://dx.doi.org/10.1210/jc.2012-4223DOI Listing
July 2013

A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.

Authors:
Eleonora Porcu Marco Medici Giorgio Pistis Claudia B Volpato Scott G Wilson Anne R Cappola Steffan D Bos Joris Deelen Martin den Heijer Rachel M Freathy Jari Lahti Chunyu Liu Lorna M Lopez Ilja M Nolte Jeffrey R O'Connell Toshiko Tanaka Stella Trompet Alice Arnold Stefania Bandinelli Marian Beekman Stefan Böhringer Suzanne J Brown Brendan M Buckley Clara Camaschella Anton J M de Craen Gail Davies Marieke C H de Visser Ian Ford Tom Forsen Timothy M Frayling Laura Fugazzola Martin Gögele Andrew T Hattersley Ad R Hermus Albert Hofman Jeanine J Houwing-Duistermaat Richard A Jensen Eero Kajantie Margreet Kloppenburg Ee M Lim Corrado Masciullo Stefano Mariotti Cosetta Minelli Braxton D Mitchell Ramaiah Nagaraja Romana T Netea-Maier Aarno Palotie Luca Persani Maria G Piras Bruce M Psaty Katri Räikkönen J Brent Richards Fernando Rivadeneira Cinzia Sala Mona M Sabra Naveed Sattar Beverley M Shields Nicole Soranzo John M Starr David J Stott Fred C G J Sweep Gianluca Usala Melanie M van der Klauw Diana van Heemst Alies van Mullem Sita H Vermeulen W Edward Visser John P Walsh Rudi G J Westendorp Elisabeth Widen Guangju Zhai Francesco Cucca Ian J Deary Johan G Eriksson Luigi Ferrucci Caroline S Fox J Wouter Jukema Lambertus A Kiemeney Peter P Pramstaller David Schlessinger Alan R Shuldiner Eline P Slagboom André G Uitterlinden Bijay Vaidya Theo J Visser Bruce H R Wolffenbuttel Ingrid Meulenbelt Jerome I Rotter Tim D Spector Andrew A Hicks Daniela Toniolo Serena Sanna Robin P Peeters Silvia Naitza

PLoS Genet 2013 7;9(2):e1003266. Epub 2013 Feb 7.

Istituto di Ricerca Genetica e Biomedica (IRGB), Consiglio Nazionale delle Ricerche, c/o Cittadella Universitaria di Monserrato, Monserrato, Cagliari, Italy.

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http://dx.doi.org/10.1371/journal.pgen.1003266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567175PMC
June 2013

The importance of measuring ionized calcium in characterizing calcium status and diagnosing primary hyperparathyroidism.

J Clin Endocrinol Metab 2012 Sep 28;97(9):3138-45. Epub 2012 Jun 28.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands 6009, Australia.

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http://dx.doi.org/10.1210/jc.2012-1429DOI Listing
September 2012

Age-related changes in thyroid function: a longitudinal study of a community-based cohort.

J Clin Endocrinol Metab 2012 May 16;97(5):1554-62. Epub 2012 Feb 16.

School of Population Health, The University of Western Australia, Nedlands, Western Australia 6009, Australia.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2011-3020DOI Listing
May 2012

The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling.

Biochem J 2012 Feb;441(3):995-1006

‡Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia.

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http://biochemj.org/lookup/doi/10.1042/BJ20111277
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http://dx.doi.org/10.1042/BJ20111277DOI Listing
February 2012

Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling.

Biochem Biophys Res Commun 2011 Sep 6;412(4):584-9. Epub 2011 Aug 6.

Western Australian Institute for Medical Research and Centre for Medical Research, University of Western Australia, Nedlands, Western Australia 6009, Australia.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1101377
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http://dx.doi.org/10.1016/j.bbrc.2011.07.132DOI Listing
September 2011

Thyrotropin and thyroid antibodies as predictors of hypothyroidism: a 13-year, longitudinal study of a community-based cohort using current immunoassay techniques.

J Clin Endocrinol Metab 2010 Mar 22;95(3):1095-104. Epub 2010 Jan 22.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009.

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http://dx.doi.org/10.1210/jc.2009-1977DOI Listing
March 2010

Genetic loci linked to pituitary-thyroid axis set points: a genome-wide scan of a large twin cohort.

J Clin Endocrinol Metab 2008 Sep 8;93(9):3519-23. Epub 2008 Jul 8.

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia 6009.

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http://dx.doi.org/10.1210/jc.2007-2650DOI Listing
September 2008

Assessment of thyroid function during pregnancy: first-trimester (weeks 9-13) reference intervals derived from Western Australian women.

Med J Aust 2008 Sep;189(5):250-3

Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, and School of Medicine and Pharmacology, University of Western Australia, Perth, WA, Australia.

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September 2008