Publications Authored by Suzanne D Turner

The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status.

Nat Commun 2019 Nov 28;10(1):5428. Epub 2019 Nov 28.

Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Lab Block level 3, Box 231, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1038/s41467-019-13315-x	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883072	PMC

November 2019

Cell of Origin and Immunologic Events in the Pathogenesis of Breast Implant-Associated Anaplastic Large-Cell Lymphoma.

Authors:

Suzanne D Turner Giorgio Inghirami Roberto N Miranda Marshall E Kadin

Am J Pathol 2019 Oct 11. Epub 2019 Oct 11.

Department of Dermatology, Roger Williams Medical Center, Providence, Rhode Island; Boston University School of Medicine, Boston, Massachusetts.

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https://linkinghub.elsevier.com/retrieve/pii/S00029440193075	Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2019.09.005	DOI Listing

October 2019

NPM-ALK Is a Key Regulator of the Oncoprotein FOXM1 in ALK-Positive Anaplastic Large Cell Lymphoma.

Authors:

Moinul Haque Jing Li Yung-Hsing Huang Meaad Almowaled Carter J Barger Adam R Karpf Peng Wang Will Chen Suzanne D Turner Raymond Lai

Cancers (Basel) 2019 Aug 6;11(8). Epub 2019 Aug 6.

Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB T6G2R3, Canada.

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http://dx.doi.org/10.3390/cancers11081119	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721812	PMC

August 2019

The Transcriptional Roles of ALK Fusion Proteins in Tumorigenesis.

Authors:

Stephen P Ducray Karthikraj Natarajan Gavin D Garland Suzanne D Turner Gerda Egger

Cancers (Basel) 2019 Jul 30;11(8). Epub 2019 Jul 30.

Department of Pathology, Medical University Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers11081074	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721376	PMC

July 2019

From bench to bedside: the past, present and future of therapy for systemic paediatric ALCL, ALK.

Authors:

Hugo Larose G A Amos Burke Eric J Lowe Suzanne D Turner

Br J Haematol 2019 Jun 25;185(6):1043-1054. Epub 2019 Jan 25.

Department of Pathology, Division of Cellular and Molecular Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1111/bjh.15763	DOI Listing

June 2019

Commentary on: Deposition of Host Matrix Proteins on Breast Implant Surfaces Facilitates Staphylococcus Epidermidis Biofilm Formation: In Vitro Analysis.

Authors:

Suzanne D Turner

Aesthet Surg J 2019 Jun 5. Epub 2019 Jun 5.

University Reader in Cellular and Molecular Tumour Biology, Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/asj/sjz144	DOI Listing

June 2019

Opportunities and challenges of circulating biomarkers in neuroblastoma.

Authors:

Ricky M Trigg Jacqui A Shaw Suzanne D Turner

Open Biol 2019 May;9(5):190056

1 Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge , Cambridge CB2 0QQ , UK.

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http://dx.doi.org/10.1098/rsob.190056	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544987	PMC

May 2019

Is breast implant-associated anaplastic large cell lymphoma a hazard of breast implant surgery?

Authors:

Florian Fitzal Suzanne D Turner Lukas Kenner

Open Biol 2019 04;9(4):190006

3 Ludwig Boltzmann Institute for Cancer Research , 1090 Vienna , Austria.

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http://dx.doi.org/10.1098/rsob.190006	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501645	PMC

April 2019

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma.

Leukemia 2019 03 21;33(3):696-709. Epub 2018 Aug 21.

Clinical Institute of Pathology, Department for Experimental and Laboratory Animal Pathology, Medical University of Vienna, Vienna, Austria.

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http://www.nature.com/articles/s41375-018-0239-1	Publisher Site
http://dx.doi.org/10.1038/s41375-018-0239-1	DOI Listing

March 2019

Commentary on: Validation of a CD30 Enzyme-Linked Immunosorbant Assay for the Rapid Detection of Breast Implant-Associated Anaplastic Large Cell Lymphoma.

Authors:

Suzanne D Turner Penny Wright

Aesthet Surg J 2019 Feb 21. Epub 2019 Feb 21.

Department of Pathology, University of Cambridge, and the Department of Histopathology, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1093/asj/sjz025	DOI Listing

February 2019

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma.

Leukemia 2018 09 28;32(9):1994-2007. Epub 2018 Mar 28.

Max-Delbrück-Center for Molecular Medicine, 13125, Berlin, Germany.

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http://dx.doi.org/10.1038/s41375-018-0045-9	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127090	PMC

September 2018

ALK in Neuroblastoma: Biological and Therapeutic Implications.

Authors:

Ricky M Trigg Suzanne D Turner

Cancers (Basel) 2018 Apr 10;10(4). Epub 2018 Apr 10.

Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.3390/cancers10040113	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923368	PMC

April 2018

The Role of Activator Protein-1 (AP-1) Family Members in CD30-Positive Lymphomas.

Authors:

Ines Garces de Los Fayos Alonso Huan-Chang Liang Suzanne D Turner Sabine Lagger Olaf Merkel Lukas Kenner

Cancers (Basel) 2018 Mar 28;10(4). Epub 2018 Mar 28.

Ludwig Boltzmann Institute for Cancer Research, 1090 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers10040093	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923348	PMC

March 2018

Treatment Options for Paediatric Anaplastic Large Cell Lymphoma (ALCL): Current Standard and beyond.

Authors:

Nina Prokoph Hugo Larose Megan S Lim G A Amos Burke Suzanne D Turner

Cancers (Basel) 2018 Mar 30;10(4). Epub 2018 Mar 30.

Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.3390/cancers10040099	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923354	PMC

March 2018

Developing the WCRF International/University of Bristol Methodology for Identifying and Carrying Out Systematic Reviews of Mechanisms of Exposure-Cancer Associations.

Cancer Epidemiol Biomarkers Prev 2017 11 4;26(11):1667-1675. Epub 2017 Oct 4.

Bristol Medical School, Population Health Sciences, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-17-0232	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029666	PMC

November 2017

When the guardian sleeps: Reactivation of the p53 pathway in cancer.

Authors:

Olaf Merkel Ninon Taylor Nicole Prutsch Philipp B Staber Richard Moriggl Suzanne D Turner Lukas Kenner

Mutat Res 2017 07 17;773:1-13. Epub 2017 Feb 17.

Department of Clinical Pathology, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria; Ludwig Boltzmann Institute for Cancer Research, Waehringerstrasse 13a, 1090 Vienna, Austria; Institute of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Veterinaerplatz 1, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.mrrev.2017.02.003	DOI Listing

July 2017

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis.

Authors:

Sean Harrison Rosie Lennon Jeff Holly Julian P T Higgins Mike Gardner Claire Perks Tom Gaunt Vanessa Tan Cath Borwick Pauline Emmet Mona Jeffreys Kate Northstone Sabina Rinaldi Stephen Thomas Suzanne D Turner Anna Pease Vicky Vilenchick Richard M Martin Sarah J Lewis

Cancer Causes Control 2017 Jun 30;28(6):497-528. Epub 2017 Mar 30.

School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1007/s10552-017-0883-1	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400803	PMC

June 2017

New avenues for targeted therapies and biomarkers in anaplastic large cell lymphoma.

Authors:

Gerda Egger Suzanne D Turner

Epigenomics 2017 02 18;9(2):97-100. Epub 2017 Jan 18.

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Lab Block Level 3, Addenbrooke's Hospital, Cambridge CB20QQ, UK.

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http://dx.doi.org/10.2217/epi-2016-0159	DOI Listing

February 2017

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling.

Authors:

Melanie R Hassler Walter Pulverer Ranjani Lakshminarasimhan Elisa Redl Julia Hacker Gavin D Garland Olaf Merkel Ana-Iris Schiefer Ingrid Simonitsch-Klupp Lukas Kenner Daniel J Weisenberger Andreas Weinhaeusel Suzanne D Turner Gerda Egger

Cell Rep 2016 10;17(2):596-608

Clinical Institute of Pathology, Medical University of Vienna, 1090 Vienna, Austria; European Research Initiative on ALK-Related Malignancies (ERIA), Cambridge CB2 0QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.09.018	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6066089	PMC

October 2016

Challenging perspectives on the cellular origins of lymphoma.

Authors:

Tim I M Malcolm Daniel J Hodson Elizabeth A Macintyre Suzanne D Turner

Open Biol 2016 Sep;6(9)

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Lab Block Level 3, Box 231, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043587	PMC
http://dx.doi.org/10.1098/rsob.160232	DOI Listing

September 2016

Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency.

Authors:

Monica Ceccon Maria Elena Boggio Merlo Luca Mologni Teresa Poggio Lydia M Varesio Matteo Menotti Silvia Bombelli Roberta Rigolio Andrea D Manazza Filomena Di Giacomo Chiara Ambrogio Giovanni Giudici Cesare Casati Cristina Mastini Mara Compagno Suzanne D Turner Carlo Gambacorti-Passerini Roberto Chiarle Claudia Voena

Oncogene 2016 07 14;35(29):3854-3865. Epub 2015 Dec 14.

Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907875	PMC
http://dx.doi.org/10.1038/onc.2015.456	DOI Listing

July 2016

Anaplastic large cell lymphoma in paediatric and young adult patients.

Authors:

Suzanne D Turner Laurence Lamant Lukas Kenner Laurence Brugières

Br J Haematol 2016 05 23;173(4):560-72. Epub 2016 Feb 23.

European Research Initiative for ALK related Malignancies, Toulouse, France.

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http://dx.doi.org/10.1111/bjh.13958	DOI Listing

May 2016

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress.

Nat Commun 2016 Jan 12;7:10087. Epub 2016 Jan 12.

Department of Pathology, University of Cambridge, Cambridge CB21QP, UK.

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http://dx.doi.org/10.1038/ncomms10087	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729925	PMC

January 2016

Stem cell hunt in NHL.

Authors:

Olaf Merkel Lukas Kenner Suzanne D Turner

Oncoscience 2015 3;2(10):809-10. Epub 2015 Sep 3.

Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge; European Research Initiative on ALK Related Malignancies ( http://www.erialcl.net ).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671931	PMC
http://dx.doi.org/10.18632/oncoscience.234	DOI Listing

December 2015

Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis.

Nat Commun 2015 Oct 26;6:8802. Epub 2015 Oct 26.

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http://dx.doi.org/10.1038/ncomms9802	DOI Listing

October 2015

Oncogenic role of miR-155 in anaplastic large cell lymphoma lacking the t(2;5) translocation.

Authors:

Olaf Merkel Frank Hamacher Robert Griessl Lisa Grabner Ana-Iris Schiefer Nicole Prutsch Constance Baer Gerda Egger Michaela Schlederer Peter William Krenn Tanja Nicole Hartmann Ingrid Simonitsch-Klupp Christoph Plass Philipp Bernhard Staber Richard Moriggl Suzanne D Turner Richard Greil Lukas Kenner

J Pathol 2015 Aug 27;236(4):445-56. Epub 2015 Apr 27.

Department of Clinical Pathology, Medical University Vienna, Austria.

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http://dx.doi.org/10.1002/path.4539	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557053	PMC

August 2015

STAT3 regulated ARF expression suppresses prostate cancer metastasis.

Nat Commun 2015 Jul 22;6:7736. Epub 2015 Jul 22.

1] Ludwig Boltzmann Institute for Cancer Research, Waehringerstrasse 13A, 1090 Vienna, Austria [2] Clinical Institute of Pathology, Medical University of Vienna, 1090 Vienna, Austria [3] Unit of Pathology of Laboratory Animals (UPLA), University of Veterinary Medicine Vienna, 1210 Vienna, Austria.

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http://dx.doi.org/10.1038/ncomms8736	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525303	PMC

July 2015

Twenty years of modelling NPM-ALK-induced lymphomagenesis.

Authors:

Sylvie Giuriato Suzanne D Turner

Front Biosci (Schol Ed) 2015 Jun 1;7:236-47. Epub 2015 Jun 1.

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Lab Block Level 3, Box 231, Addenbrooke's Hospital, Cambridge CB20QQ, UK,

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June 2015

Neonatal opioid withdrawal and antenatal opioid prescribing.

Authors:

Suzanne D Turner Tara Gomes Ximena Camacho Zhan Yao Astrid Guttmann Muhammad M Mamdani David N Juurlink Irfan A Dhalla

CMAJ Open 2015 Jan-Mar;3(1):E55-61. Epub 2015 Jan 13.

Institute for Clinical Evaluative Sciences ; Department of Medicine, University of Toronto ; Department of Medicine, St. Michael's Hospital.

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http://dx.doi.org/10.9778/cmajo.20140065	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382031	PMC

April 2015

Anaplastic large cell lymphoma (ALCL) and breast implants: breaking down the evidence.

Authors:

Xuan Ye Kayvan Shokrollahi Warren M Rozen Rachel Conyers Penny Wright Lukas Kenner Suzanne D Turner Iain S Whitaker

Mutat Res Rev Mutat Res 2014 Oct-Dec;762:123-32. Epub 2014 Aug 23.

Institute of Life Science, Swansea University College of Medicine, Singleton Park, SA2 8PP Swansea, Wales, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S13835742140004	Publisher Site
http://dx.doi.org/10.1016/j.mrrev.2014.08.002	DOI Listing

February 2015

Approach to cannabis use disorder in primary care: focus on youth and other high-risk users.

Authors:

Suzanne D Turner Sheryl Spithoff Meldon Kahan

Can Fam Physician 2014 Sep;60(9):801-8, e423-32

Medical Director of the Substance Use Service at Women's College Hospital.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162694	PMC

September 2014

Rapid point-of-care HIV testing in youth: a systematic review.

Authors:

Suzanne D Turner Kelly Anderson Morgan Slater Laura Quigley Martin Dyck Charlie B Guiang

J Adolesc Health 2013 Dec 19;53(6):683-91. Epub 2013 Sep 19.

Postgraduate Medical Education, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada; Department of Family and Community Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jadohealth.2013.07.029	DOI Listing

December 2013

Malignant transformation of CD4+ T lymphocytes mediated by oncogenic kinase NPM/ALK recapitulates IL-2-induced cell signaling and gene expression reprogramming.

Authors:

Michal Marzec Krzysztof Halasa Xiaobin Liu Hong Y Wang Mangeng Cheng Donald Baldwin John W Tobias Stephen J Schuster Anders Woetmann Qian Zhang Suzanne D Turner Niels Ødum Mariusz A Wasik

J Immunol 2013 Dec 11;191(12):6200-7. Epub 2013 Nov 11.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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http://dx.doi.org/10.4049/jimmunol.1300744	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889215	PMC

December 2013

Assessment of the transforming potential of novel anaplastic lymphoma kinase point mutants.

Authors:

Fiona K E McDuff Su-Vern Lim Melis Dalbay Suzanne D Turner

Mol Carcinog 2013 Jan 15;52(1):79-83. Epub 2011 Nov 15.

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Lab Block Level 3, Box 231, Addenbrooke's Hospital, Cambridge, UK.

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http://doi.wiley.com/10.1002/mc.21836	Publisher Site
http://dx.doi.org/10.1002/mc.21836	DOI Listing

January 2013

PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.

Nat Med 2012 Nov 14;18(11):1699-704. Epub 2012 Oct 14.

Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/nm.2966	DOI Listing

November 2012

Determining the contribution of NPM1 heterozygosity to NPM-ALK-induced lymphomagenesis.

Authors:

Fiona K E Mduff C Elizabeth Hook Reuben M Tooze Brian J Huntly Pier Paolo Pandolfi Suzanne D Turner

Lab Invest 2011 Sep 27;91(9):1298-303. Epub 2011 Jun 27.

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/labinvest.2011.96	DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166849	PMC

September 2011

The lymphoma-associated NPM-ALK oncogene elicits a p16INK4a/pRb-dependent tumor-suppressive pathway.

Authors:

Paola Martinelli Paola Bonetti Cristina Sironi Giancarlo Pruneri Caterina Fumagalli Paola Rafaniello Raviele Sara Volorio Stefano Pileri Roberto Chiarle Fiona Kate Elizabeth McDuff Betsabeh Khoramian Tusi Suzanne D Turner Giorgio Inghirami Pier Giuseppe Pelicci Emanuela Colombo

Blood 2011 Jun 25;117(24):6617-26. Epub 2011 Apr 25.

Department of Experimental Oncology, European Institute of Oncology, Via Adamello 16, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2010-08-301135	DOI Listing

June 2011

Jailbreak: oncogene-induced senescence and its evasion.

Authors:

Fiona K E McDuff Suzanne D Turner

Cell Signal 2011 Jan 13;23(1):6-13. Epub 2010 Jul 13.

Division of Molecular Histopathology, Department of Pathology, University of Cambridge, Lab Block Level 3, Addenbrooke's Hospital, Cambridge, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S08986568100019	Publisher Site
http://dx.doi.org/10.1016/j.cellsig.2010.07.004	DOI Listing

January 2011

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma.

Authors:

Olaf Merkel Frank Hamacher Daniela Laimer Eveline Sifft Zlatko Trajanoski Marcel Scheideler Gerda Egger Melanie R Hassler Christiane Thallinger Ana Schmatz Suzanne D Turner Richard Greil Lukas Kenner

Proc Natl Acad Sci U S A 2010 Sep 30;107(37):16228-33. Epub 2010 Aug 30.

Laboratory for Immunological and Molecular Cancer Research, Third Medical Department with Hematology, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria.

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