Publications by authors named "Sushant Kumar"

31Publications

SVFX: a machine learning framework to quantify the pathogenicity of structural variants.

Genome Biol 2020 Nov 9;21(1):274. Epub 2020 Nov 9.

Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-020-02178-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7650198PMC
November 2020

Enriched oxygen vacancies of CuO/SnS/SnO heterostructure for enhanced photocatalytic reduction of CO by water and nitrogen fixation.

J Colloid Interface Sci 2020 Oct 20. Epub 2020 Oct 20.

Gas-Solid Interaction Laboratory, Department of Chemical and Biochemical Engineering, Indian Institute of Technology Patna, Bihta, Patna 801 106, Bihar, India. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcis.2020.10.056DOI Listing
October 2020

Spin-phonon relaxation from a universal ab initio density-matrix approach.

Nat Commun 2020 Jun 3;11(1):2780. Epub 2020 Jun 3.

Department of Chemistry and Biochemistry, University of California, Santa Cruz, CA, 95064, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-020-16063-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270186PMC
June 2020

Hydrogenation properties and kinetic study of MgH - x wt% AC nanocomposites prepared by ball milling.

Environ Sci Pollut Res Int 2020 May 11. Epub 2020 May 11.

Department of Physics, University of Rajasthan Jaipur, JLN Marg, Jaipur, Rajasthan, 302004, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11356-020-08964-1DOI Listing
May 2020

Passenger Mutations in More Than 2,500 Cancer Genomes: Overall Molecular Functional Impact and Consequences.

Cell 2020 03 20;180(5):915-927.e16. Epub 2020 Feb 20.

Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA; Department of Computer Science, Yale University, New Haven, CT 06511, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2020.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210002PMC
March 2020

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Nature 2020 02 5;578(7793):102-111. Epub 2020 Feb 5.

The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41586-020-1965-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7054214PMC
February 2020

Isolation and structural characterization of a Zn-bound single-domain antibody against NorC, a putative multidrug efflux transporter in bacteria.

J Biol Chem 2020 01 7;295(1):55-68. Epub 2019 Nov 7.

Molecular Biophysics Unit, Indian Institute of Science, CV Raman Road, Bengaluru 560012, India

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.RA119.010902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952597PMC
January 2020

Leveraging protein dynamics to identify cancer mutational hotspots using 3D structures.

Proc Natl Acad Sci U S A 2019 09 28;116(38):18962-18970. Epub 2019 Aug 28.

Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1901156116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754584PMC
September 2019

Hydrogel scaffold with substrate elasticity mimicking physiological-niche promotes proliferation of functional keratinocytes.

RSC Adv 2019 Apr 1;9(18):10174-10183. Epub 2019 Apr 1.

Department of Biosciences & Bioengineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra 400076, India. Email:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9ra00781dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592153PMC
April 2019

Multi-platform discovery of haplotype-resolved structural variation in human genomes.

Nat Commun 2019 04 16;10(1):1784. Epub 2019 Apr 16.

The Jackson Laboratory for Genomic Medicine, Farmington, CT, 06032, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/s41467-018-08148-z
Publisher Site
http://dx.doi.org/10.1038/s41467-018-08148-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467913PMC
April 2019

Ultrafast Electron Dynamics in Single Aluminum Nanostructures.

Nano Lett 2019 05 8;19(5):3091-3097. Epub 2019 Apr 8.

Department of Materials Science and Engineering , Rensselaer Polytechnic Institute , Troy , New York 12180 , United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.nanolett.9b00503DOI Listing
May 2019

Extracellular methemoglobin promotes cyto-adherence of uninfected RBC to endothelial cells: Insight into cerebral malaria pathology.

J Cell Biochem 2019 Jan 30. Epub 2019 Jan 30.

Malaria Research Group, Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, Assam, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.28390DOI Listing
January 2019

Crystal structure of the retroviral protease-like domain of a protozoal DNA damage-inducible 1 protein.

FEBS Open Bio 2018 Sep 3;8(9):1379-1394. Epub 2018 Aug 3.

Molecular Biophysics Unit Indian Institute of Science Bangalore India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/2211-5463.12491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120238PMC
September 2018

New tetrameric forms of the rotavirus NSP4 with antiparallel helices.

Arch Virol 2018 Jun 17;163(6):1531-1547. Epub 2018 Feb 17.

Molecular Biophysics Unit, Indian Institute of Science, Bangalore, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00705-018-3753-6DOI Listing
June 2018

Kimura Disease: A Rare Case Report From Himalayan Region.

Indian J Otolaryngol Head Neck Surg 2017 Dec 5;69(4):571-574. Epub 2017 Jan 5.

Department of Otolaryngology and HNS (ENT), AIIMS, Virbhadra Marg, Rishikesh, Uttarakhand 240201 India.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s12070-016-1045-6
Publisher Site
http://dx.doi.org/10.1007/s12070-016-1045-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714899PMC
December 2017

Anticancer Potential of Thiazole Derivatives: A Retrospective Review.

Mini Rev Med Chem 2018 ;18(8):640-655

Pharmacy College, Uttar Pradesh University of Medical Sciences, Saifai, Etawah (U.P.) 206130, India.

View Article

Download full-text PDF

Source
http://www.eurekaselect.com/157757/article
Publisher Site
http://dx.doi.org/10.2174/1389557517666171123211321DOI Listing
May 2018

Cancer genomics: Less is more in the hunt for driver mutations.

Nature 2017 07 28;547(7661):40-41. Epub 2017 Jun 28.

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature23085DOI Listing
July 2017

B16 Lung Melanoma Model to Study the Role of Th9 Cells in Cancer.

Methods Mol Biol 2017 ;1585:217-222

Department of Bioscience and Bioengineering, Indian Institute of Technology Bombay (IIT Bombay), Mumbai, Maharashtra, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-6877-0_17DOI Listing
February 2018

Blockade of Rho-associated protein kinase (ROCK) inhibits the contractility and invasion potential of cancer stem like cells.

Oncotarget 2017 Mar;8(13):21418-21428

Department of Biosciences & Bioengineering, Indian Institute of Technology Bombay (IIT Bombay), Mumbai, Maharashtra, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.15248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400594PMC
March 2017

Localized structural frustration for evaluating the impact of sequence variants.

Nucleic Acids Res 2016 12 18;44(21):10062-10073. Epub 2016 Oct 18.

Program in Computational Biology and Bioinformatics, Yale University, 260/266 Whitney Avenue PO Box 208114, New Haven, CT 06520, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkw927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137452PMC
December 2016

Identifying Allosteric Hotspots with Dynamics: Application to Inter- and Intra-species Conservation.

Structure 2016 05 7;24(5):826-837. Epub 2016 Apr 7.

Program in Computational Biology and Bioinformatics, Yale University, 260/266 Whitney Avenue, PO Box 208114, New Haven, CT 06520, USA; Department of Molecular Biophysics and Biochemistry, Yale University, 260/266 Whitney Avenue, PO Box 208114, New Haven, CT 06520, USA; Department of Computer Science, Yale University, 260/266 Whitney Avenue, PO Box 208114, New Haven, CT 06520, USA. Electronic address:

View Article

Download full-text PDF

Source
http://www.cell.com/structure/pdf/S0969-2126(16)00086-1.pdf
Web Search
http://dx.doi.org/10.1016/j.str.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883016PMC
May 2016

Reads meet rotamers: structural biology in the age of deep sequencing.

Curr Opin Struct Biol 2015 Dec 1;35:125-34. Epub 2015 Dec 1.

Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, United States; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.sbi.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751031PMC
December 2015

Engineering high-performance Pd core-MgO porous shell nanocatalysts via heterogeneous gas-phase synthesis.

Nanoscale 2015 Aug 23;7(32):13387-92. Epub 2015 Jul 23.

Nanoparticles by Design Unit, Okinawa Institute of Science and Technology Graduate University, Onna, Okinawa 904-0495, Japan.

View Article

Download full-text PDF

Source
http://www.rsc.org/suppdata/c5/nr/c5nr02663f/c5nr02663f1.pdf
Web Search
http://xlink.rsc.org/?DOI=C5NR02663F
Publisher Site
http://dx.doi.org/10.1039/c5nr02663fDOI Listing
August 2015

Role of Ordered Proteins in the Folding-Upon-Binding of Intrinsically Disordered Proteins.

J Phys Chem Lett 2014 Mar 17;5(5):833-8. Epub 2014 Feb 17.

§Department of Chemistry and †Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jz402729xDOI Listing
March 2014

Native-based simulations of the binding interaction between RAP74 and the disordered FCP1 peptide.

J Phys Chem B 2013 Mar 12;117(11):3074-85. Epub 2013 Mar 12.

Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jp310293bDOI Listing
March 2013

Atomistic simulations reveal structural disorder in the RAP74-FCP1 complex.

J Phys Chem B 2011 Nov 27;115(46):13731-9. Epub 2011 Oct 27.

Department of Chemistry, The Pennsylvania State University, 104 Chemistry Building, University Park, Pennsylvania 16802, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jp208008mDOI Listing
November 2011