Publications by authors named "Susanne Vrtala"

61Publications

Expression in and Purification of Folded rDer p 20, the Arginine Kinase From : A Possible Biomarker for Allergic Asthma.

Allergy Asthma Immunol Res 2021 Jan;13(1):154-163

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.4168/aair.2021.13.1.154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7680834PMC
January 2021

Microarray-Based Detection of Allergen-Reactive IgE in Patients with Mastocytosis.

J Allergy Clin Immunol Pract 2020 Sep 26;8(8):2761-2768.e16. Epub 2020 Apr 26.

Department of Internal Medicine I, Division of Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2020.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116130PMC
September 2020

Molecular profiling of allergen-specific antibody responses may enhance success of specific immunotherapy.

J Allergy Clin Immunol 2020 Nov 13;146(5):1097-1108. Epub 2020 Apr 13.

Department of Pathophysiology and Allergy Research, Division of Immunopathology, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna and Krems, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2020.03.029DOI Listing
November 2020

A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens.

Allergy 2019 12 3;74(12):2461-2478. Epub 2019 Oct 3.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1111/all.13956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078969PMC
December 2019

Selection of house dust mite-allergic patients by molecular diagnosis may enhance success of specific immunotherapy.

J Allergy Clin Immunol 2019 03 14;143(3):1248-1252.e12. Epub 2018 Nov 14.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183159
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http://dx.doi.org/10.1016/j.jaci.2018.10.048DOI Listing
March 2019

Underestimation of house dust mite-specific IgE with extract-based ImmunoCAPs compared with molecular ImmunoCAPs.

J Allergy Clin Immunol 2018 11 27;142(5):1656-1659.e9. Epub 2018 Jul 27.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183106
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http://dx.doi.org/10.1016/j.jaci.2018.07.010DOI Listing
November 2018

Tropomyosins in mosquito and house dust mite cross-react at the humoral and cellular level.

Clin Exp Allergy 2018 10 14;48(10):1354-1363. Epub 2018 Aug 14.

Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.

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http://doi.wiley.com/10.1111/cea.13229
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http://dx.doi.org/10.1111/cea.13229DOI Listing
October 2018

Recombinant allergen and peptide-based approaches for allergy prevention by oral tolerance.

Semin Immunol 2017 04 20;30:67-80. Epub 2017 Sep 20.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2017.08.017DOI Listing
April 2017

Innate function of house dust mite allergens: robust enzymatic degradation of extracellular matrix at elevated pH.

World Allergy Organ J 2017 4;10(1):23. Epub 2017 Jul 4.

The interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University Vienna and University Vienna, Veterinaerplatz 1, 1210 Vienna, Austria.

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http://dx.doi.org/10.1186/s40413-017-0154-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496134PMC
July 2017

Identification by serological proteome analysis of paramyosin as prominent allergen in dust mite allergy.

J Proteomics 2017 08 4;166:19-26. Epub 2017 Jul 4.

Cellular and Molecular Allergology Unit, IRCCS-San Raffaele Hospital, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2017.06.024DOI Listing
August 2017

Clinical validation of a house dust mite environmental challenge chamber model.

J Allergy Clin Immunol 2017 07 24;140(1):266-268.e5. Epub 2017 Feb 24.

Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jaci.2016.12.986DOI Listing
July 2017

Real-Life Study for the Diagnosis of House Dust Mite Allergy - The Value of Recombinant Allergen-Based IgE Serology.

Int Arch Allergy Immunol 2016 10;170(2):132-7. Epub 2016 Aug 10.

Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center, Johannes Gutenberg University, Mainz, Germany.

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http://dx.doi.org/10.1159/000447694DOI Listing
February 2017

Specific IgE and IgG measured by the MeDALL allergen-chip depend on allergen and route of exposure: The EGEA study.

J Allergy Clin Immunol 2017 02 22;139(2):643-654.e6. Epub 2016 Jun 22.

INSERM U1168, VIMA (Aging and chronic diseases. Epidemiological and public health approaches), Villejuif, France; Univ Versailles St-Quentin-en-Yvelines, Montigny le Bretonneux, France; University Hospital, Montpellier, France.

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http://dx.doi.org/10.1016/j.jaci.2016.05.023DOI Listing
February 2017

Different IgE recognition of mite allergen components in asthmatic and nonasthmatic children.

J Allergy Clin Immunol 2015 Oct 5;136(4):1083-91. Epub 2015 May 5.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for the Development of Allergen Chips, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.03.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595482PMC
October 2015

Prevention of allergic asthma through Der p 2 peptide vaccination.

J Allergy Clin Immunol 2015 Jul 11;136(1):197-200.e1. Epub 2015 Feb 11.

INSERM, UMR1087, l'institut du thorax, Nantes, France; CNRS, UMR 6291, Nantes, France; Université de Nantes, Nantes, France; DHU2020 médecine personnalisée des maladies chroniques, Nantes, France; CHU de Nantes, l'institut du thorax, Service de Pneumologie, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.12.1938DOI Listing
July 2015

Wheat allergy in children evaluated with challenge and IgE antibodies to wheat components.

Pediatr Allergy Immunol 2015 Mar;26(2):119-25

Q204 Lung/Allergy Department, Karolinska Institutet and Karolinska University Hospital, Astrid Lindgren Children's Hospital, Stockholm, Sweden; Centre for Allergy Research, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/pai.12334DOI Listing
March 2015

Biochemical, biophysical and IgE-epitope characterization of the wheat food allergen, Tri a 37.

PLoS One 2014 4;9(11):e111483. Epub 2014 Nov 4.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111483PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219751PMC
June 2015

Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen.

PLoS One 2014 2;9(9):e109075. Epub 2014 Oct 2.

Christian Doppler Laboratory for Immunomodulation, Medical University of Vienna, Vienna, Austria; Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109075PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183528PMC
June 2015

Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis.

J Invest Dermatol 2015 Jan 7;135(1):102-109. Epub 2014 Aug 7.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for the Development of Allergen Chips, Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636057PMC
January 2015

Conversion of Der p 23, a new major house dust mite allergen, into a hypoallergenic vaccine.

J Immunol 2014 May 14;192(10):4867-75. Epub 2014 Apr 14.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology, and Immunology, Medical University of Vienna, 1090 Vienna, Austria;

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http://dx.doi.org/10.4049/jimmunol.1400064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582415PMC
May 2014

Specific IgE reactivity to Tri a 36 in children with wheat food allergy.

J Allergy Clin Immunol 2014 Feb 12;133(2):585-7. Epub 2013 Dec 12.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology & Immunology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria; Christian Doppler Laboratory for Allergy Research, Medical University of Vienna, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.10.044DOI Listing
February 2014

Recombinant house dust mite allergens.

Methods 2014 Mar 31;66(1):67-74. Epub 2013 Jul 31.

Center for Child Health Research, University of Western Australia, Telethon Institute of Child Health Research, West Perth, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2013.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582397PMC
March 2014

α-Purothionin, a new wheat allergen associated with severe allergy.

J Allergy Clin Immunol 2013 Oct 28;132(4):1000-3.e1-4. Epub 2013 Jun 28.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna General Hospital, Austria; Christian Doppler Laboratory for the Development of Allergen Chips, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1016/j.jaci.2013.05.016DOI Listing
October 2013

Molecular and immunological characterization of Tri a 36, a low molecular weight glutenin, as a novel major wheat food allergen.

J Immunol 2012 Sep 17;189(6):3018-25. Epub 2012 Aug 17.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology, and Immunology, Medical University of Vienna, Vienna General Hospital, 1090 Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.1200438DOI Listing
September 2012

Hypoallergenic Der p 1/Der p 2 combination vaccines for immunotherapy of house dust mite allergy.

J Allergy Clin Immunol 2012 Aug 11;130(2):435-43.e4. Epub 2012 Jul 11.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jaci.2012.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594766PMC
August 2012

Varying allergen composition and content affects the in vivo allergenic activity of commercial Dermatophagoides pteronyssinus extracts.

Int Arch Allergy Immunol 2012 21;159(3):253-62. Epub 2012 Jun 21.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000337654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594775PMC
December 2012

Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination.

Vaccine 2011 Mar 5;29(11):2140-8. Epub 2011 Jan 5.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.vaccine.2010.12.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092211PMC
March 2011

Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.

Mol Immunol 2011 Jan 18;48(4):431-41. Epub 2010 Nov 18.

Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center of Pathophysiology, Infectiology and Immunology, Vienna General Hospital (AKH), Medical University of Vienna, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.molimm.2010.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067515PMC
January 2011

Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly.

J Allergy Clin Immunol 2010 Nov 16;126(5):1024-31, 1031.e1-8. Epub 2010 Jul 16.

Division of Immunopathology, Department of Pathophysiology, Center of Pathophysiology, Infectiology and Immunology, Vienna General Hospital (AKH), Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1016/j.jaci.2010.05.023DOI Listing
November 2010

A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6.

Biol Chem 2008 Jul;389(7):925-33

Division of Immunopathology, Department of Pathophysiology, Center of Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1515/BC.2008.105DOI Listing
July 2008

Characterization of folded recombinant Der p 5, a potential diagnostic marker allergen for house dust mite allergy.

Int Arch Allergy Immunol 2008 3;147(2):101-9. Epub 2008 Jun 3.

Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1159/000135696DOI Listing
October 2008

Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering.

Mol Immunol 2008 May 4;45(9):2486-98. Epub 2008 Mar 4.

Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.molimm.2008.01.006DOI Listing
May 2008

Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2.

Mol Immunol 2008 Mar 26;45(5):1308-17. Epub 2007 Oct 26.

Department of Pathophysiology, Center of Physiology, Pathophysiology and Immunology, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria.

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http://dx.doi.org/10.1016/j.molimm.2007.09.012DOI Listing
March 2008

Genetic engineering of the major timothy grass pollen allergen, Phl p 6, to reduce allergenic activity and preserve immunogenicity.

J Immunol 2007 Aug;179(3):1730-9

Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.179.3.1730DOI Listing
August 2007

Immunization with a low-dose replicon DNA vaccine encoding Phl p 5 effectively prevents allergic sensitization.

J Allergy Clin Immunol 2006 Sep 6;118(3):734-41. Epub 2006 Jun 6.

Christian Doppler Laboratory for Allergy Diagnostic and Therapy, Department of Molecular Biology, University of Salzburg, Austria.

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http://dx.doi.org/10.1016/j.jaci.2006.04.048DOI Listing
September 2006

Allergen cleavage by effector cell-derived proteases regulates allergic inflammation.

FASEB J 2006 May 3;20(7):967-9. Epub 2006 Apr 3.

Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Austria.

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http://dx.doi.org/10.1096/fj.05-3999fjeDOI Listing
May 2006

Strategies for converting allergens into hypoallergenic vaccine candidates.

Methods 2004 Mar;32(3):313-20

Department of Pathophysiology, University of Vienna, Vienna A-1090, Austria.

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http://dx.doi.org/10.1016/j.ymeth.2003.08.016DOI Listing
March 2004

Synthetic and genetically engineered allergen derivatives for specific immunotherapy of type I allergy.

Clin Allergy Immunol 2002 ;16:495-517

Vienna General Hospital (AKH), University of Vienna Medical School, Vienna, Austria.

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April 2002