Publications by authors named "Susan Strome"

58Publications

SET1/COMPASS Maintains Germline Identity by Preventing Transcriptional Deregulation Across Generations.

Front Cell Dev Biol 2020 22;8:561791. Epub 2020 Sep 22.

Laboratory of Biology and Modeling of the Cell, Ecole Normale Supérieure de Lyon, CNRS, Université Claude Bernard de Lyon, Université de Lyon, Lyon, France.

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http://dx.doi.org/10.3389/fcell.2020.561791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536326PMC
September 2020

Chromatin and epigenetics in development: a Special Issue.

Development 2019 10 10;146(19). Epub 2019 Oct 10.

Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Marchioninistraße 25, D-81377 München, Germany.

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http://dx.doi.org/10.1242/dev.185025DOI Listing
October 2019

Repression of Germline Genes in Somatic Tissues by H3K9 Dimethylation of Their Promoters.

Genetics 2019 05 25;212(1):125-140. Epub 2019 Mar 25.

Department of Biological Sciences, Marquette University, Milwaukee, Wisconsin 53201

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http://dx.doi.org/10.1534/genetics.118.301878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499516PMC
May 2019

Sperm-inherited H3K27me3 impacts offspring transcription and development in C. elegans.

Nat Commun 2019 03 20;10(1):1271. Epub 2019 Mar 20.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA, 95064, USA.

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http://dx.doi.org/10.1038/s41467-019-09141-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426959PMC
March 2019

Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis.

Nat Commun 2018 10 17;9(1):4310. Epub 2018 Oct 17.

Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA, 95064, USA.

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http://dx.doi.org/10.1038/s41467-018-06236-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193031PMC
October 2018

Distinct Roles of Two Histone Methyltransferases in Transmitting H3K36me3-Based Epigenetic Memory Across Generations in .

Genetics 2018 11 14;210(3):969-982. Epub 2018 Sep 14.

Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California 95064

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http://dx.doi.org/10.1534/genetics.118.301353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218224PMC
November 2018

Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes.

PLoS Genet 2017 Nov 1;13(11):e1007088. Epub 2017 Nov 1.

Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683655PMC
November 2017

Germ Granules Prevent Accumulation of Somatic Transcripts in the Adult Germline.

Genetics 2017 05 3;206(1):163-178. Epub 2017 Mar 3.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, California 95064

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http://www.genetics.org/lookup/doi/10.1534/genetics.116.1985
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http://dx.doi.org/10.1534/genetics.116.198549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419467PMC
May 2017

Inheritance of protection from osmotic stress.

Nat Cell Biol 2017 03;19(3):151-152

Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California 95064, USA.

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http://dx.doi.org/10.1038/ncb3483DOI Listing
March 2017

A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans.

PLoS Genet 2016 08 19;12(8):e1006227. Epub 2016 Aug 19.

Biology Department, Emory University, Atlanta, Georgia, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4991786PMC
August 2016

Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters.

Nat Commun 2016 07 28;7:12301. Epub 2016 Jul 28.

Department of Chemistry and Biochemistry, University of California, 1156 High Street, Santa Cruz, California 95064, USA.

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http://dx.doi.org/10.1038/ncomms12301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974476PMC
July 2016

Reevaluation of whether a soma-to-germ-line transformation extends lifespan in Caenorhabditis elegans.

Proc Natl Acad Sci U S A 2016 Mar 14;113(13):3591-6. Epub 2016 Mar 14.

Department of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, CA 95064

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http://dx.doi.org/10.1073/pnas.1523402113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822628PMC
March 2016

Caenorhabditis elegans polo-like kinase PLK-1 is required for merging parental genomes into a single nucleus.

Mol Biol Cell 2015 Dec 21;26(25):4718-35. Epub 2015 Oct 21.

Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892

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http://dx.doi.org/10.1091/mbc.E15-04-0244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678026PMC
December 2015

Specifying and protecting germ cell fate.

Nat Rev Mol Cell Biol 2015 Jul;16(7):406-16

Kathryn W. Davis Center for Regenerative Biology &Medicine, Mount Desert Island Biological Laboratory, Bar Harbor, Maine 04672, USA.

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http://dx.doi.org/10.1038/nrm4009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698964PMC
July 2015

Defining heterochromatin in C. elegans through genome-wide analysis of the heterochromatin protein 1 homolog HPL-2.

Genome Res 2015 Jan 2;25(1):76-88. Epub 2014 Dec 2.

Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California 95064, USA;

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http://dx.doi.org/10.1101/gr.180489.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317175PMC
January 2015

Gene repression. H3K27me and PRC2 transmit a memory of repression across generations and during development.

Science 2014 Sep 18;345(6203):1515-8. Epub 2014 Sep 18.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA. Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://dx.doi.org/10.1126/science.1255023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238426PMC
September 2014

Comparative analysis of metazoan chromatin organization.

Nature 2014 Aug;512(7515):449-52

1] Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts 02115, USA [2] Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA [3] Informatics Program, Children's Hospital, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/nature13415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227084PMC
August 2014

Germ-granule components prevent somatic development in the C. elegans germline.

Curr Biol 2014 May 17;24(9):970-5. Epub 2014 Apr 17.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1016/j.cub.2014.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036631PMC
May 2014

Regulation of the X chromosomes in Caenorhabditis elegans.

Cold Spring Harb Perspect Biol 2014 Mar 1;6(3). Epub 2014 Mar 1.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California 95064.

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http://dx.doi.org/10.1101/cshperspect.a018366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942922PMC
March 2014

Opposing activities of DRM and MES-4 tune gene expression and X-chromosome repression in Caenorhabditis elegans germ cells.

G3 (Bethesda) 2014 Jan 10;4(1):143-53. Epub 2014 Jan 10.

Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605.

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http://dx.doi.org/10.1534/g3.113.007849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887530PMC
January 2014

Antagonism between MES-4 and Polycomb repressive complex 2 promotes appropriate gene expression in C. elegans germ cells.

Cell Rep 2012 Nov 25;2(5):1169-77. Epub 2012 Oct 25.

Department of Molecular, Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1016/j.celrep.2012.09.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513488PMC
November 2012

An inverse relationship to germline transcription defines centromeric chromatin in C. elegans.

Nature 2012 Apr 8;484(7395):534-7. Epub 2012 Apr 8.

Ludwig Institute for Cancer Research and Department of Cellular & Molecular Medicine, University of California San Diego, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nature10973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538161PMC
April 2012

P granules extend the nuclear pore complex environment in the C. elegans germ line.

J Cell Biol 2011 Mar 14;192(6):939-48. Epub 2011 Mar 14.

Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201010104
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http://dx.doi.org/10.1083/jcb.201010104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063144PMC
March 2011

Neuroscience. Toward reprogramming gonads to brains.

Authors:
Susan Strome

Science 2011 Jan;331(6015):292-3

Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.1126/science.1201288DOI Listing
January 2011

Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project.

Authors:
Mark B Gerstein Zhi John Lu Eric L Van Nostrand Chao Cheng Bradley I Arshinoff Tao Liu Kevin Y Yip Rebecca Robilotto Andreas Rechtsteiner Kohta Ikegami Pedro Alves Aurelien Chateigner Marc Perry Mitzi Morris Raymond K Auerbach Xin Feng Jing Leng Anne Vielle Wei Niu Kahn Rhrissorrakrai Ashish Agarwal Roger P Alexander Galt Barber Cathleen M Brdlik Jennifer Brennan Jeremy Jean Brouillet Adrian Carr Ming-Sin Cheung Hiram Clawson Sergio Contrino Luke O Dannenberg Abby F Dernburg Arshad Desai Lindsay Dick Andréa C Dosé Jiang Du Thea Egelhofer Sevinc Ercan Ghia Euskirchen Brent Ewing Elise A Feingold Reto Gassmann Peter J Good Phil Green Francois Gullier Michelle Gutwein Mark S Guyer Lukas Habegger Ting Han Jorja G Henikoff Stefan R Henz Angie Hinrichs Heather Holster Tony Hyman A Leo Iniguez Judith Janette Morten Jensen Masaomi Kato W James Kent Ellen Kephart Vishal Khivansara Ekta Khurana John K Kim Paulina Kolasinska-Zwierz Eric C Lai Isabel Latorre Amber Leahey Suzanna Lewis Paul Lloyd Lucas Lochovsky Rebecca F Lowdon Yaniv Lubling Rachel Lyne Michael MacCoss Sebastian D Mackowiak Marco Mangone Sheldon McKay Desirea Mecenas Gennifer Merrihew David M Miller Andrew Muroyama John I Murray Siew-Loon Ooi Hoang Pham Taryn Phippen Elicia A Preston Nikolaus Rajewsky Gunnar Rätsch Heidi Rosenbaum Joel Rozowsky Kim Rutherford Peter Ruzanov Mihail Sarov Rajkumar Sasidharan Andrea Sboner Paul Scheid Eran Segal Hyunjin Shin Chong Shou Frank J Slack Cindie Slightam Richard Smith William C Spencer E O Stinson Scott Taing Teruaki Takasaki Dionne Vafeados Ksenia Voronina Guilin Wang Nicole L Washington Christina M Whittle Beijing Wu Koon-Kiu Yan Georg Zeller Zheng Zha Mei Zhong Xingliang Zhou Julie Ahringer Susan Strome Kristin C Gunsalus Gos Micklem X Shirley Liu Valerie Reinke Stuart K Kim LaDeana W Hillier Steven Henikoff Fabio Piano Michael Snyder Lincoln Stein Jason D Lieb Robert H Waterston

Science 2010 Dec 22;330(6012):1775-87. Epub 2010 Dec 22.

Program in Computational Biology and Bioinformatics, Yale University, Bass 432, 266 Whitney Avenue, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1126/science.1196914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142569PMC
December 2010

Caenorhabditis elegans chromosome arms are anchored to the nuclear membrane via discontinuous association with LEM-2.

Genome Biol 2010 23;11(12):R120. Epub 2010 Dec 23.

Department of Biology, Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, 407 Fordham Hall, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1186/gb-2010-11-12-r120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046480PMC
June 2011

The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny.

PLoS Genet 2010 Sep 2;6(9):e1001091. Epub 2010 Sep 2.

Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932692PMC
September 2010

P granule assembly and function in Caenorhabditis elegans germ cells.

J Androl 2010 Jan-Feb;31(1):53-60. Epub 2009 Oct 29.

Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.

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http://dx.doi.org/10.2164/jandrol.109.008292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905540PMC
June 2010

A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans.

Genetics 2009 Dec 5;183(4):1397-419. Epub 2009 Oct 5.

Department of Molecular Cell and Developmental Biology, University of California, Santa Cruz, California 95064, USA.

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http://www.genetics.org/lookup/doi/10.1534/genetics.109.1101
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http://dx.doi.org/10.1534/genetics.109.110171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787428PMC
December 2009

A mutation of cdc-25.1 causes defects in germ cells but not in somatic tissues in C. elegans.

Mol Cells 2009 Jul 12;28(1):43-8. Epub 2009 Jun 12.

Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Seoul 143-701, Korea.

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http://dx.doi.org/10.1007/s10059-009-0098-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908335PMC
July 2009

DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells.

Development 2008 Mar 30;135(5):983-93. Epub 2008 Jan 30.

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.015552
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http://dx.doi.org/10.1242/dev.015552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435365PMC
March 2008

Specification of the germ line.

Authors:
Susan Strome

WormBook 2005 Jul 28:1-10. Epub 2005 Jul 28.

Department of Biology, Indiana University, Bloomington, IN 47405-3700, USA.

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http://dx.doi.org/10.1895/wormbook.1.9.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781390PMC
July 2005

Germ versus soma decisions: lessons from flies and worms.

Science 2007 Apr;316(5823):392-3

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1140846
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http://dx.doi.org/10.1126/science.1140846DOI Listing
April 2007

MRG-1, an autosome-associated protein, silences X-linked genes and protects germline immortality in Caenorhabditis elegans.

Development 2007 Feb 10;134(4):757-67. Epub 2007 Jan 10.

Department of Biology, Graduate School of Science and Technology, Kobe University, 1-1 Rokkodaicho, Nadaku, Kobe 657-8501, Japan.

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http://dx.doi.org/10.1242/dev.02771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435364PMC
February 2007

Subunit contributions to histone methyltransferase activities of fly and worm polycomb group complexes.

Mol Cell Biol 2005 Aug;25(16):6857-68

Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, 55455, USA.

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http://dx.doi.org/10.1128/MCB.25.16.6857-6868.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1190254PMC
August 2005

Functional analysis of cytoplasmic dynein heavy chain in Caenorhabditis elegans with fast-acting temperature-sensitive mutations.

Mol Biol Cell 2005 Mar 22;16(3):1200-12. Epub 2004 Dec 22.

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://dx.doi.org/10.1091/mbc.e04-06-0523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC551485PMC
March 2005

The MES-2/MES-3/MES-6 complex and regulation of histone H3 methylation in C. elegans.

Curr Biol 2004 Sep;14(18):1639-43

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://dx.doi.org/10.1016/j.cub.2004.08.062DOI Listing
September 2004

C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes.

Curr Biol 2004 May;14(10):851-62

Department of Biology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.cub.2004.05.022DOI Listing
May 2004

Germ plasm: protein degradation in the soma.

Curr Biol 2003 Oct;13(21):R837-9

Department of Biology, Indiana University, Bloomington 47405-3700, USA.

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http://dx.doi.org/10.1016/j.cub.2003.10.016DOI Listing
October 2003

KLP-18, a Klp2 kinesin, is required for assembly of acentrosomal meiotic spindles in Caenorhabditis elegans.

Mol Biol Cell 2003 Nov 22;14(11):4458-69. Epub 2003 Aug 22.

Institut für Genetik, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany.

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http://dx.doi.org/10.1091/mbc.e03-05-0283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC266765PMC
November 2003

Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C. elegans.

Science 2002 Jun;296(5576):2235-8

Department of Biology, Indiana University, Bloomington, IN 47405, USA.

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http://dx.doi.org/10.1126/science.1070790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435369PMC
June 2002