Publications by authors named "Susan Sergeant"

33Publications

Impact of rs174537 on Critically Ill Patients with Acute Lung Injury: A Secondary Analysis of the OMEGA Randomized Clinical Trial.

Curr Dev Nutr 2020 Oct 14;4(10):nzaa147. Epub 2020 Sep 14.

Department of Biomedical Engineering, Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1093/cdn/nzaa147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524639PMC
October 2020

Acyl-lipid desaturases and Vipp1 cooperate in cyanobacteria to produce novel omega-3 PUFA-containing glycolipids.

Biotechnol Biofuels 2020 6;13:83. Epub 2020 May 6.

3Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157 USA.

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http://dx.doi.org/10.1186/s13068-020-01719-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203895PMC
May 2020

Allele-specific methylation in the genomic region in DNA from human saliva, CD4+ cells, and total leukocytes.

Clin Epigenetics 2018 6;10:46. Epub 2018 Apr 6.

3Department of Physiology and Pharmacology, Wake Forest School of Medicine, 575 N. Patterson Ave. Suite 310, Winston-Salem, NC 27101 USA.

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http://dx.doi.org/10.1186/s13148-018-0480-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889567PMC
February 2019

Precision Nutrition and Omega-3 Polyunsaturated Fatty Acids: A Case for Personalized Supplementation Approaches for the Prevention and Management of Human Diseases.

Nutrients 2017 Oct 25;9(11). Epub 2017 Oct 25.

Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.

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http://www.mdpi.com/2072-6643/9/11/1165
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http://dx.doi.org/10.3390/nu9111165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707637PMC
October 2017

Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes.

Eur J Pharmacol 2016 Aug 12;785:77-86. Epub 2016 Apr 12.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, One Medical Center Blvd, Winston-Salem, NC 27157, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00142999163023
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http://dx.doi.org/10.1016/j.ejphar.2016.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975646PMC
August 2016

Alterations in levels and ratios of n-3 and n-6 polyunsaturated fatty acids in the temporal cortex and liver of vervet monkeys from birth to early adulthood.

Physiol Behav 2016 Mar 17;156:71-8. Epub 2015 Dec 17.

Department of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA; The Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. Electronic address:

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http://dx.doi.org/10.1016/j.physbeh.2015.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772874PMC
March 2016

Impact of methods used to express levels of circulating fatty acids on the degree and direction of associations with blood lipids in humans.

Br J Nutr 2016 Jan 30;115(2):251-61. Epub 2015 Nov 30.

1Center for Botanical Lipids and Inflammatory Disease Prevention,Wake Forest School of Medicine,Medical Center Blvd,Winston-Salem,NC 27157,USA.

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http://dx.doi.org/10.1017/S0007114515004341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4697295PMC
January 2016

The impact of polyunsaturated fatty acid-based dietary supplements on disease biomarkers in a metabolic syndrome/diabetes population.

Lipids Health Dis 2014 Dec 16;13:196. Epub 2014 Dec 16.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, Medical Center Blvd,, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1186/1476-511X-13-196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290816PMC
December 2014

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.

J Biol Chem 2014 Aug 24;289(32):22482-9. Epub 2014 Jun 24.

the Department of Physiology/Pharmacology, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157, the Molecular Medicine and Translation Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157

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http://dx.doi.org/10.1074/jbc.M114.579557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139254PMC
August 2014

Diet-gene interactions and PUFA metabolism: a potential contributor to health disparities and human diseases.

Nutrients 2014 May 21;6(5):1993-2022. Epub 2014 May 21.

Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.3390/nu6051993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042578PMC
May 2014

DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

PLoS One 2014 19;9(5):e97510. Epub 2014 May 19.

Department of Physiology/Pharmacology, Wake Forest Health Sciences, Winston-Salem, North Carolina, United States of America; Wake Forest Center for Botanical Lipids and Inflammatory Disease Prevention, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026313PMC
December 2014

Measurement of phospholipid metabolism in intact neutrophils.

Methods Mol Biol 2014 ;1124:89-105

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1007/978-1-62703-845-4_7DOI Listing
October 2014

An online optimism intervention reduces depression in pessimistic individuals.

J Consult Clin Psychol 2014 Apr 13;82(2):263-74. Epub 2014 Jan 13.

Psychology Department, York University.

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http://dx.doi.org/10.1037/a0035536DOI Listing
April 2014

Impact of botanical oils on polyunsaturated fatty acid metabolism and leukotriene generation in mild asthmatics.

Lipids Health Dis 2013 Oct 2;12:141. Epub 2013 Oct 2.

Department of Physiology/Pharmacology, Wake Forest School of Medicine, Medical Center Blvd, 27157, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1186/1476-511X-12-141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3851449PMC
October 2013

Adaptive evolution of the FADS gene cluster within Africa.

PLoS One 2012 19;7(9):e44926. Epub 2012 Sep 19.

Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446990PMC
March 2013

Dietary fish oil modestly attenuates the effect of age on diastolic function but has no effect on memory or brain inflammation in aged rats.

J Gerontol A Biol Sci Med Sci 2011 May 10;66(5):521-33. Epub 2011 Mar 10.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1009, USA.

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http://dx.doi.org/10.1093/gerona/glr017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074961PMC
May 2011

Depression and altered serum lipids in cynomolgus monkeys consuming a Western diet.

Physiol Behav 2011 Aug 20;104(2):222-7. Epub 2011 Jan 20.

Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.physbeh.2011.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085547PMC
August 2011

Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding.

J Biol Chem 2010 Jan 30;285(5):2959-67. Epub 2009 Nov 30.

From the Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157 and.

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http://dx.doi.org/10.1074/jbc.M109.030643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2823407PMC
January 2010

X-linked chronic granulomatous disease secondary to skewed X chromosome inactivation in a female with a novel CYBB mutation and late presentation.

Clin Immunol 2008 Nov 6;129(2):372-80. Epub 2008 Sep 6.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.clim.2008.07.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2599929PMC
November 2008

Mutations in the PX-SH3A linker of p47phox decouple PI(3,4)P2 binding from NADPH oxidase activation.

Biochemistry 2008 Aug 2;47(34):8855-65. Epub 2008 Aug 2.

Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1016, USA.

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http://dx.doi.org/10.1021/bi8005847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745045PMC
August 2008

Measurement of phospholipid metabolism in intact neutrophils.

Methods Mol Biol 2007 ;412:69-83

Department of Biochemistry, Wake Forest University, School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1007/978-1-59745-467-4_6DOI Listing
June 2008

Novel translocation responses of cytosolic phospholipase A2alpha fluorescent proteins.

Biochim Biophys Acta 2008 Aug 21;1783(8):1544-50. Epub 2008 Mar 21.

Department of Internal Medicine, Section on Infectious Diseases, Wake Forest University Health Sciences, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2008.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474710PMC
August 2008