Publications by authors named "Susan R Rittling"

55Publications

Modulation of infection-mediated migration of neutrophils and CXCR2 trafficking by osteopontin.

Immunology 2017 Jan 7;150(1):74-86. Epub 2016 Oct 7.

Department of Immunology and Infectious Diseases, The Forsyth Institute, Cambridge, MA, USA.

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http://dx.doi.org/10.1111/imm.12668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5341506PMC
January 2017

Early Cytokine Response to Infection with Pathogenic vs Non-Pathogenic Organisms in a Mouse Model of Endodontic Infection.

PLoS One 2015 14;10(7):e0132752. Epub 2015 Jul 14.

The Forsyth Institute, Cambridge, Massachusetts, United States of America; Harvard School of Dental Medicine, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132752PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501552PMC
April 2016

Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin.

Matrix Biol 2015 Jan 29;41:19-25. Epub 2014 Nov 29.

Department of Immunology and Infectious Disease, The Forsyth Institute, Cambridge, MA, USA; Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2014.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912046PMC
January 2015

Pathogenic bacterial species associated with endodontic infection evade innate immune control by disabling neutrophils.

Infect Immun 2014 Oct 14;82(10):4068-79. Epub 2014 Jul 14.

Department of Immunology and Infectious Diseases, The Forsyth Institute, Cambridge, Massachusetts, USA Harvard School of Dental Medicine, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/IAI.02256-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187851PMC
October 2014

Osteopontin in macrophage function.

Authors:
Susan R Rittling

Expert Rev Mol Med 2011 Apr 26;13:e15. Epub 2011 Apr 26.

The Forsyth Institute, 245 First St, Cambridge, MA 02142, USA.

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http://dx.doi.org/10.1017/S1462399411001839DOI Listing
April 2011

Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages.

Arthritis Rheum 2010 May;62(5):1329-37

International Research Center for Molecular Science in Tooth and Bone Diseases, and Tokyo Medical and Dental University, Tokyo, Japan.

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http://doi.wiley.com/10.1002/art.27400
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http://dx.doi.org/10.1002/art.27400DOI Listing
May 2010

Protective role of osteopontin in endodontic infection.

Immunology 2010 Jan 11;129(1):105-14. Epub 2009 Sep 11.

Department of Cytokine Biology, The Forsyth Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1111/j.1365-2567.2009.03159.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807491PMC
January 2010

Transforming growth factor-beta1 regulation of ATF-3 and identification of ATF-3 target genes in breast cancer cells.

J Cell Biochem 2009 Oct;108(2):408-14

Department of Physiology and Biophysics, UMDNJ-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1002/jcb.22267DOI Listing
October 2009

Both cell-surface and secreted CSF-1 expressed by tumor cells metastatic to bone can contribute to osteoclast activation.

Exp Cell Res 2009 Aug 8;315(14):2442-52. Epub 2009 May 8.

Department of Cytokine Biology, The Forsyth Institute, Boston, MA 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270900199
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http://dx.doi.org/10.1016/j.yexcr.2009.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704245PMC
August 2009

Effect of osteopontin on diarrhea duration and innate immunity in suckling mice infected with a murine rotavirus.

Viral Immunol 2009 Apr;22(2):139-44

Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1089/vim.2008.0054DOI Listing
April 2009

Osteopontin is dispensable for protection against high load systemic fungal infection.

Int Immunopharmacol 2008 Oct 30;8(10):1441-8. Epub 2008 Jun 30.

Fermentation Research Laboratories, Astellas Pharmaceutical Inc., Tokodai 5-2-3, Tsukuba, Ibaraki, 300-2698, Japan.

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http://dx.doi.org/10.1016/j.intimp.2008.06.001DOI Listing
October 2008

Osteopontin negatively regulates parathyroid hormone receptor signaling in osteoblasts.

J Biol Chem 2008 Jul 16;283(28):19400-9. Epub 2008 Apr 16.

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510, Tokyo, Japan.

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http://dx.doi.org/10.1074/jbc.M800005200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762377PMC
July 2008

Corneal wound healing in an osteopontin-deficient mouse.

Invest Ophthalmol Vis Sci 2008 Apr;49(4):1367-75

Department of Ophthalmology, Wakayama Medical University, Wakayama, Japan.

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http://dx.doi.org/10.1167/iovs.07-1007DOI Listing
April 2008

OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application.

J Cell Physiol 2008 Mar;214(3):614-20

Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1002/jcp.21250DOI Listing
March 2008

Characterization of anti-osteopontin monoclonal antibodies: Binding sensitivity to post-translational modifications.

J Cell Biochem 2007 Nov;102(4):925-35

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway New Jersey, USA.

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http://dx.doi.org/10.1002/jcb.21487DOI Listing
November 2007

Cell type-specific post-translational modifications of mouse osteopontin are associated with different adhesive properties.

J Biol Chem 2007 Jul 11;282(27):19463-72. Epub 2007 May 11.

Protein Chemistry Laboratory, Department of Molecular Biology, University of Aarhus, DK-8000 Aarhus C, Denmark.

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http://dx.doi.org/10.1074/jbc.M703055200DOI Listing
July 2007

Osteopontin is required for mechanical stress-dependent signals to bone marrow cells.

J Endocrinol 2007 May;193(2):235-43

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10, Kanda-Surugadai 2-Chome, Tokyo, Japan.

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http://dx.doi.org/10.1677/joe.1.06704DOI Listing
May 2007

Osteopontin deficiency enhances anabolic action of EP4 agonist at a sub-optimal dose in bone.

J Endocrinol 2007 Apr;193(1):171-82

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10 Kanda-Surugadai 2-Chome, Tokyo, Japan.

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https://joe.bioscientifica.com/doi/10.1677/joe.1.06917
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http://dx.doi.org/10.1677/joe.1.06917DOI Listing
April 2007

Osteopontin is associated with nuclear factor kappaB gene expression during tail-suspension-induced bone loss.

Exp Cell Res 2006 Oct 7;312(16):3075-83. Epub 2006 Jun 7.

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, 3-10, Kanda-Surugadai 2-Chome, Chiyoda-Ku, Tokyo 101-0062, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S001448270600219
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http://dx.doi.org/10.1016/j.yexcr.2006.06.003DOI Listing
October 2006

A mouse model of breast cancer metastasis to the choroid of the eye.

Clin Exp Metastasis 2005 18;22(8):685-90. Epub 2006 May 18.

Department of Genetics, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1007/s10585-006-9012-3DOI Listing
October 2006

Override of the osteoclast defect in osteopontin-deficient mice by metastatic tumor growth in the bone.

Am J Pathol 2006 Feb;168(2):551-61

Department of Genetics, Rutgers University, Piscataway, New Jersey, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606503PMC
http://dx.doi.org/10.2353/ajpath.2006.050480DOI Listing
February 2006

Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: osteopontin localization.

Kidney Int 2005 Jul;68(1):145-54

Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, Indiana 46220, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S008525381550821
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http://dx.doi.org/10.1111/j.1523-1755.2005.00388.xDOI Listing
July 2005

Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size.

J Exp Med 2005 Jun 31;201(11):1781-91. Epub 2005 May 31.

Center for Regenerative Medicine and Technology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://www.jem.org/lookup/doi/10.1084/jem.20041992
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http://dx.doi.org/10.1084/jem.20041992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213260PMC
June 2005

Osteoclasts resorb protein-free mineral (Osteologic discs) efficiently in the absence of osteopontin.

In Vivo 2005 Mar-Apr;19(2):335-41

Program in BioTechnology, Kean University, 1000 Morris Avenue, Union, NJ 07083, USA.

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July 2005

Impaired anti-tumor cytotoxicity of macrophages from osteopontin-deficient mice.

Cell Immunol 2004 Jan;227(1):1-11

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ 08854, USA.

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http://dx.doi.org/10.1016/j.cellimm.2004.01.001DOI Listing
January 2004

Osteopontin expression in osteoblasts and osteocytes during bone formation under mechanical stress in the calvarial suture in vivo.

J Bone Miner Res 2003 Sep;18(9):1706-15

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1359/jbmr.2003.18.9.1706DOI Listing
September 2003

Rho-dependent Rho kinase activation increases CD44 surface expression and bone resorption in osteoclasts.

J Biol Chem 2003 Aug 1;278(31):29086-97. Epub 2003 May 1.

Department of Oral Craniofacial Biological Sciences, University of Maryland, Baltimore, Maryland 21201, USA.

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http://dx.doi.org/10.1074/jbc.M211074200DOI Listing
August 2003

Osteopontin deficiency attenuates atherosclerosis in female apolipoprotein E-deficient mice.

Arterioscler Thromb Vasc Biol 2003 Jun 1;23(6):1029-34. Epub 2003 May 1.

Division of Molecular Immunology, Institute for Genetic Medicine, Hokkaido University, Kita-15, Nishi-7, Kita-ku, Sapporo 060-0815, Japan.

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http://dx.doi.org/10.1161/01.ATV.0000074878.29805.D0DOI Listing
June 2003

Novel murine mammary epithelial cell lines that form osteolytic bone metastases: effect of strain background on tumor homing.

Clin Exp Metastasis 2003 ;20(2):111-20

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854, USA.

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http://dx.doi.org/10.1023/a:1022675031185DOI Listing
May 2003

Osteopontin deficiency induces parathyroid hormone enhancement of cortical bone formation.

Endocrinology 2003 May;144(5):2132-40

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1210/en.2002-220996DOI Listing
May 2003

Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice.

Proc Natl Acad Sci U S A 2002 Apr;99(7):4556-61

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 101-0062, Japan.

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http://dx.doi.org/10.1073/pnas.052523599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123686PMC
April 2002

Resistance to unloading-induced three-dimensional bone loss in osteopontin-deficient mice.

J Bone Miner Res 2002 Apr;17(4):661-7

Department of Molecular Pharmacology, Medical Research Institute, Tokyo Medical and Dental University, Japan.

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http://dx.doi.org/10.1359/jbmr.2002.17.4.661DOI Listing
April 2002

Role of osteopontin in murine Lyme arthritis and host defense against Borrelia burgdorferi.

Infect Immun 2002 Mar;70(3):1372-81

Department of Pathology, Division of Cell Biology and Immunology, University of Utah School of Medicine, Salt Lake City, Utah 84132-2501, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC127811PMC
http://dx.doi.org/10.1128/iai.70.3.1372-1381.2002DOI Listing
March 2002

Tumor-derived osteopontin is soluble, not matrix associated.

J Biol Chem 2002 Mar 12;277(11):9175-82. Epub 2001 Dec 12.

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey 08854-8082, USA.

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http://dx.doi.org/10.1074/jbc.M109028200DOI Listing
March 2002