Publications by authors named "Susan Oladeji"

4 Publications

  • Page 1 of 1

Prevalence and route of transmission of undiagnosed human immunodeficiency virus infection among children using provider-initiated testing and counselling strategy in Ido-Ekiti, Nigeria: a cross-sectional study.

Pan Afr Med J 2019 1;34:62. Epub 2019 Oct 1.

Department of Ear, Nose and Throat, Benjamin Carson Senior School of Medicine, Babcock University, Ilishan-Remo, Ogun Sate, Nigeria.

Introduction: Ninety-one percent of global Human Immunodeficiency Virus (HIV) infection in children occurs in sub-Saharan Africa. Provider Initiated Testing and Counselling (PITC) Strategy is a means of reducing missed opportunities for HIV exposed or infected children. The present study determined the prevalence of HIV infection using PITC Strategy among children seen at the Paediatric Emergency Unit of Federal Medical Centre (FMC), Ido-Ekiti, and the possible route of transmission.

Methods: Cross-sectional study on prevalence of HIV infection using PITC model. 530 new patients whose HIV serostatus were unknown and aged 15 years or below were recruited consecutively and offered HIV testing. Serial algorithm testing for HIV infection using Determine HIV-1/2 and Uni-Gold rapid test kits was adopted. Seropositive patients younger than eighteen months had HIV Deoxyribonucleic Acid Polymerase Chain Reaction (HIV DNA PCR) test for confirmation.

Results: Twenty-four (4.5%) of the 530 patients were confirmed to have HIV infection; of whom 19 (79.2%) were less than 18 months of old; with age range of 5 to 156 months. Fifteen (62.5%) of the infected children were females; likewise, the gender specific infection rate was higher (%) among the females compared with (%) among the males. Two of the HIV infected children's mothers were late, while the remaining 22 mothers (%) were HIV seropositive. Mother-to-child-transmission was the most likely route of transmission in the children.

Conclusion: PITC strategy is vital to the early diagnosis and effective control of HIV infection in children. However, this cannot be totally effective if PMTCT is not optimized.
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http://dx.doi.org/10.11604/pamj.2019.34.62.9374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876896PMC
December 2019

Examination of previously published data to identify patterns in the social representation of "Loud music" in young adults across countries.

Noise Health 2018 Jan-Feb;20(92):16-22

LERASS Laboratory, University of Toulouse, Toulouse, France.

Purpose: The current study was aimed at understanding the patterns in the social representation of loud music reported by young adults in different countries.

Materials And Methods: The study included a sample of 534 young adults (18-25 years) from India, Iran, Portugal, United Kingdom, and United States. Participants were recruited using a convince sampling, and data were collected using the free association task. Participants were asked to provide up to five words or phrases that come to mind when thinking about "loud music." The data were first analyzed using the qualitative content analysis. This was followed by quantitative cluster analysis and chi-square analysis.

Results: The content analysis suggested 19 main categories of responses related to loud music. The cluster analysis resulted in for main clusters, namely: (1) emotional oriented perception; (2) problem oriented perception; (3) music and enjoyment oriented perception; and (4) positive emotional and recreation-oriented perception. Country of origin was associated with the likelihood of participants being in each of these clusters.

Conclusion: The current study highlights the differences and similarities in young adults' perception of loud music. These results may have implications to hearing health education to facilitate healthy listening habits.
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http://dx.doi.org/10.4103/nah.NAH_21_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843985PMC
August 2019

Prevalence and determinants of susceptibility to cigarette smoking among non-smoking senior secondary school students in Ilorin, North Central Nigeria.

Int J Adolesc Med Health 2017 Oct 11;30(5). Epub 2017 Oct 11.

Department of Community Health, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.

Background Globally, efforts are being made to control tobacco use. However, adolescents who are susceptible to cigarette smoking constitute a major challenge to control efforts. Defining the magnitude of susceptible adolescents and associated factors in any setting is critical to the development of measures that will successfully address this issue. This study estimated the prevalence and factors associated with susceptibility to cigarette smoking among non smoking students in Ilorin, North Central Nigeria. Methods A cross sectional study involving 2000 secondary school students selected via multistage sampling technique. Data was collected using a self administered questionnaire, while analysis was done using SPSS 16.0. Results Prevalence of susceptibility to cigarette smoking among non smoking respondents was 13.6% (14.5% among males and 11.4% among females, respectively). Factors associated with susceptibility to cigarette smoking were parental smoking habit [odds ratio (OR) = 4.43], having close friends who smoke (OR = 6.54), engagement in vocational training (OR = 1.39), exposure to environmental tobacco smoke at home (OR = 1.61), knowledge of harmful effects of tobacco (OR = 2.35) and perceptions of the effect of cigarette smoking such as enhancing attractive among boys (OR = 2.03), and causing weight gain among boys (OR = 2.39) and among girls (OR = 6.05). Conclusion The high prevalence of susceptibility to cigarette smoking among the non smoking students highlights the potential for future increase in prevalence of cigarette smoking in the setting. Efforts at controlling cigarette smoking will not be totally successful if susceptibility to cigarette smoking among adolescents is not addressed.
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http://dx.doi.org/10.1515/ijamh-2016-0099DOI Listing
October 2017

Clinical predictors of aminoglycoside-induced ototoxicity in drug-resistant Tuberculosis patients on intensive therapy.

Auris Nasus Larynx 2017 Aug 8;44(4):404-410. Epub 2016 Nov 8.

Department of Otorhinolaryngology, Ladoke Akintola University of Technology (LAUTECH) Teaching Hospital, Osogbo, Nigeria.

Objective: The study objectives were to determine the incidence of aminoglycoside-induced ototoxicity in institutionalized patients on intensive phase of therapy for drug-resistant Tuberculosis (DR Tb) and also to assess clinical factors which could predict the ototoxicity.

Methods: The study was a prospective analytical study among consecutive DR Tb patients who were admitted for intensive phase of therapy (of 4 months) at the DR-Tb center over a 12-month period. Patients were diagnosed as DR Tb using the Gene Xpert machine to confirm Rifampicin resistance. All eligible 70 out of 87 consenting patients were consecutively recruited into the study. Patients had baseline (admission) and serial pure tone audiometries (PTAs) performed at 4 weekly intervals until discharge after 4 months of admission. Audiometric confirmation of aminoglycoside-induced ototoxicity was done by comparing serial with baseline PTA.

Results: Among the 70 patients the male:female ratio was 1.7:1. Nine patients (12.9%) were retroviral-positive, and 16 patients (22.9%) were confirmed to have ototoxicity by audiometric criteria. The duration of treatment when ototoxicity was detected in the patients ranged 4-17 (Mean±SD; 9.4±3.4) weeks. Ototoxicity was detected in the audiometric low frequency ranges in 7 (43.8%) and at the high frequencies in 4 (25.0%) of the patients. Univariate analyses of clinical parameters found that age, underlying diabetes mellitus, deranged baseline PTAv >25dB HL, BMI on admission and retroviral status were significantly associated, while sex and previous drug regimen failure were not associated with ototoxicity. Multivariate adjusted logistic regression analyses, controlling for sex, revealed age (OR=1.068, p=0.018), BMI on admission (OR=0.673, p=0.012) and retroviral positivity (OR=8.822, p=0.014) of patients could significantly predict aminoglycoside-induced ototoxicity.

Conclusion: Incidence of aminoglycoside-induced ototoxicity in DR Tb patients was 22.9%. The clinical predictors for ototoxicity were age, BMI on admission, and co-existing retroviral infection in the patients. Clinicians should consider these factors in making choices of aminoglycosides to be used during intensive phase of treatment with second line anti-Tuberculous therapy.
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http://dx.doi.org/10.1016/j.anl.2016.10.005DOI Listing
August 2017
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