Susan M Freier

Susan M Freier

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Susan M Freier

Susan M Freier

Publications by authors named "Susan M Freier"

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34Publications

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Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution.

J Cell Sci 2017 Dec 13;130(24):4180-4192. Epub 2017 Nov 13.

Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1242/jcs.206854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769577PMC
December 2017

Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA.

Cell 2017 Dec;171(7):1559-1572.e20

Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, MI, USA; Department of Cellular and Molecular Biology, University of Michigan, Ann Arbor, MI, USA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI, USA; Department of Urology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734106PMC
December 2017

Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines.

Hum Mol Genet 2016 12;25(23):5178-5187

Molecular Medicine Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

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http://dx.doi.org/10.1093/hmg/ddw338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078641PMC
December 2016

Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration.

Cell Rep 2016 09;17(1):261-274

Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA; Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079290PMC
http://dx.doi.org/10.1016/j.celrep.2016.08.081DOI Listing
September 2016

Natural antisense RNA promotes 3' end processing and maturation of MALAT1 lncRNA.

Nucleic Acids Res 2016 Apr 29;44(6):2898-908. Epub 2016 Jan 29.

Department of Cell and Developmental Biology, University of Illinois Urbana, IL 61801, USA

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http://dx.doi.org/10.1093/nar/gkw047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4824109PMC
April 2016

Targeting of repeated sequences unique to a gene results in significant increases in antisense oligonucleotide potency.

PLoS One 2014 15;9(10):e110615. Epub 2014 Oct 15.

Department of Core Antisense Research, ISIS Pharmaceuticals, Inc., Carlsbad, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0110615PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198294PMC
December 2015

Identification and characterization of modified antisense oligonucleotides targeting DMPK in mice and nonhuman primates for the treatment of myotonic dystrophy type 1.

J Pharmacol Exp Ther 2015 Nov 1;355(2):329-40. Epub 2015 Sep 1.

Isis Pharmaceuticals Inc., Carlsbad, CA (S.K.P., S.L.J., A.K., H.S.Y., D.G., E.E.S., S.M.F., C.F.B., A.R.M.); Department of Neurology and Center of Neural Development and Disease, University of Rochester, Rochester, New York (T.M.W., C.A.T.); Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts (T.M.W.); and Department of Human Genetics, Centre Hospitalier Universitaire de Quebec, Quebec City, Canada (D.J., J.P.).

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http://dx.doi.org/10.1124/jpet.115.226969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613955PMC
November 2015

Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides.

Methods Mol Biol 2015 ;1262:321-31

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Room, C426, Chem. and Life Sci. Building, 601S Goodwin Avenue, Urbana-Champaign, IL, 61801, USA.

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http://link.springer.com/content/pdf/10.1007/978-1-4939-2253
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http://link.springer.com/10.1007/978-1-4939-2253-6_20
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http://dx.doi.org/10.1007/978-1-4939-2253-6_20DOI Listing
September 2015

Regulation of the ESC transcriptome by nuclear long noncoding RNAs.

Genome Res 2015 Sep 5;25(9):1336-46. Epub 2015 Jun 5.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA;

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http://dx.doi.org/10.1101/gr.189027.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561492PMC
September 2015

Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB.

PLoS Genet 2013 Mar 21;9(3):e1003368. Epub 2013 Mar 21.

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605280PMC
March 2013

Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin.

Mol Ther 2011 Dec 4;19(12):2178-85. Epub 2011 Oct 4.

Program in Neuroscience, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/mt.2011.201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242664PMC
December 2011

Control of RNA processing by a large non-coding RNA over-expressed in carcinomas.

FEBS Lett 2011 Feb 23;585(4):671-6. Epub 2011 Jan 23.

Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.febslet.2011.01.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065235PMC
February 2011

Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells.

J Cell Sci 2010 Nov 12;123(Pt 21):3734-44. Epub 2010 Oct 12.

Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Chemical and Life Sciences Laboratory, 601 South Goodwin Avenue, Urbana, IL 61801, USA.

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http://dx.doi.org/10.1242/jcs.070466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481618PMC
November 2010

Antisense oligonucleotide targeting of insulin-like growth factor-1 receptor (IGF-1R) in prostate cancer.

Prostate 2010 Feb;70(2):206-18

Vancouver Prostate Centre, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/pros.21054DOI Listing
February 2010

3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA.

Cell 2008 Nov;135(5):919-32

Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

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http://dx.doi.org/10.1016/j.cell.2008.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722846PMC
November 2008

Prediction of antisense oligonucleotide efficacy using aggregate motifs.

J Bioinform Comput Biol 2008 Oct;6(5):919-32

SciberQuest, Inc., 777 South Highway 101, Suite 108, Solana Beach, CA 92075-2623, USA.

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October 2008

Absolute quantitation of microRNAs with a PCR-based assay.

Anal Biochem 2006 Dec 8;359(2):268-70. Epub 2006 Sep 8.

Isis Pharmaceuticals, Carlsbad, CA 92008, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000326970600622
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http://dx.doi.org/10.1016/j.ab.2006.08.022DOI Listing
December 2006

Regulating gene expression through RNA nuclear retention.

Cell 2005 Oct;123(2):249-63

Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

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http://dx.doi.org/10.1016/j.cell.2005.08.033DOI Listing
October 2005