Publications by authors named "Susan Ewart"

54Publications

Interweaving Between Genetic and Epigenetic Studies on Childhood Asthma.

Epigenet Insights 2020 22;13:2516865720923395. Epub 2020 Jul 22.

Division of Epidemiology, Biostatistics, and Environmental Health Sciences, School of Public Health, The University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1177/2516865720923395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378715PMC
July 2020

Cohort Profile Update: The Isle of Wight Whole Population Birth Cohort (IOWBC).

Int J Epidemiol 2020 Jul 8. Epub 2020 Jul 8.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1093/ije/dyaa068DOI Listing
July 2020

Epigenome-Wide Association Study Reveals Duration of Breastfeeding Is Associated with Epigenetic Differences in Children.

Int J Environ Res Public Health 2020 05 20;17(10). Epub 2020 May 20.

Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.

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http://dx.doi.org/10.3390/ijerph17103569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7277240PMC
May 2020

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.

Genome Med 2020 03 2;12(1):25. Epub 2020 Mar 2.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13073-020-0716-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050134PMC
March 2020

Epigenome wide comparison of DNA methylation profile between paired umbilical cord blood and neonatal blood on Guthrie cards.

Epigenetics 2020 May 9;15(5):454-461. Epub 2019 Dec 9.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1080/15592294.2019.1699983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7188390PMC
May 2020

Estimation of Eosinophil Cells in Cord Blood with References Based on Blood in Adults via Bayesian Measurement Error Modeling.

Bioinformatics 2019 Nov 9. Epub 2019 Nov 9.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz839DOI Listing
November 2019

Comparison of smoking-related DNA methylation between newborns from prenatal exposure and adults from personal smoking.

Epigenomics 2019 10 19;11(13):1487-1500. Epub 2019 Sep 19.

Department of Health & Human Services, Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.2217/epi-2019-0066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836223PMC
October 2019

Duration of breastfeeding is associated with leptin (LEP) DNA methylation profiles and BMI in 10-year-old children.

Clin Epigenetics 2019 08 29;11(1):128. Epub 2019 Aug 29.

Human Development and Health, Faculty of Medicine, University Hospital Southampton, University of Southampton, Duthie Building, MP808, Tremona Road, Southampton, Hampshire, SO16 6YD, UK.

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http://dx.doi.org/10.1186/s13148-019-0727-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716837PMC
August 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies.

Respir Res 2018 Sep 19;19(1):179. Epub 2018 Sep 19.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1186/s12931-018-0892-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146615PMC
September 2018

DNA methylation and genetic polymorphisms of the Leptin gene interact to influence lung function outcomes and asthma at 18 years of age.

Int J Mol Epidemiol Genet 2016 23;7(1):1-17. Epub 2016 Mar 23.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis Memphis, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858611PMC
May 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Authors:
Bonnie R Joubert Janine F Felix Paul Yousefi Kelly M Bakulski Allan C Just Carrie Breton Sarah E Reese Christina A Markunas Rebecca C Richmond Cheng-Jian Xu Leanne K Küpers Sam S Oh Cathrine Hoyo Olena Gruzieva Cilla Söderhäll Lucas A Salas Nour Baïz Hongmei Zhang Johanna Lepeule Carlos Ruiz Symen Ligthart Tianyuan Wang Jack A Taylor Liesbeth Duijts Gemma C Sharp Soesma A Jankipersadsing Roy M Nilsen Ahmad Vaez M Daniele Fallin Donglei Hu Augusto A Litonjua Bernard F Fuemmeler Karen Huen Juha Kere Inger Kull Monica Cheng Munthe-Kaas Ulrike Gehring Mariona Bustamante Marie José Saurel-Coubizolles Bilal M Quraishi Jie Ren Jörg Tost Juan R Gonzalez Marjolein J Peters Siri E Håberg Zongli Xu Joyce B van Meurs Tom R Gaunt Marjan Kerkhof Eva Corpeleijn Andrew P Feinberg Celeste Eng Andrea A Baccarelli Sara E Benjamin Neelon Asa Bradman Simon Kebede Merid Anna Bergström Zdenko Herceg Hector Hernandez-Vargas Bert Brunekreef Mariona Pinart Barbara Heude Susan Ewart Jin Yao Nathanaël Lemonnier Oscar H Franco Michael C Wu Albert Hofman Wendy McArdle Pieter Van der Vlies Fahimeh Falahi Matthew W Gillman Lisa F Barcellos Ashish Kumar Magnus Wickman Stefano Guerra Marie-Aline Charles John Holloway Charles Auffray Henning W Tiemeier George Davey Smith Dirkje Postma Marie-France Hivert Brenda Eskenazi Martine Vrijheid Hasan Arshad Josep M Antó Abbas Dehghan Wilfried Karmaus Isabella Annesi-Maesano Jordi Sunyer Akram Ghantous Göran Pershagen Nina Holland Susan K Murphy Dawn L DeMeo Esteban G Burchard Christine Ladd-Acosta Harold Snieder Wenche Nystad Gerard H Koppelman Caroline L Relton Vincent W V Jaddoe Allen Wilcox Erik Melén Stephanie J London

Am J Hum Genet 2016 Apr 31;98(4):680-96. Epub 2016 Mar 31.

National Institute of Environmental Health Sciences, NIH, U.S. Department of Health and Human Services, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833289PMC
April 2016

Effects of phthalate exposure on asthma may be mediated through alterations in DNA methylation.

Clin Epigenetics 2015 15;7:27. Epub 2015 Mar 15.

Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, 48824 MI USA.

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https://clinicalepigeneticsjournal.biomedcentral.com/article
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http://dx.doi.org/10.1186/s13148-015-0060-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424541PMC
May 2015

Association of filaggrin variants with asthma and rhinitis: is eczema or allergic sensitization status an effect modifier?

Int Arch Allergy Immunol 2014 23;164(4):308-18. Epub 2014 Sep 23.

Department of Epidemiology and Biostatistics, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, S.C., USA.

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https://www.karger.com/Article/FullText/365990
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http://dx.doi.org/10.1159/000365990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281035PMC
December 2014

Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation.

Clin Epigenetics 2014 19;6(1):17. Epub 2014 Sep 19.

Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

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http://dx.doi.org/10.1186/1868-7083-6-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171400PMC
September 2014

Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence.

J Allergy Clin Immunol 2014 Oct 28;134(4):876-882.e4. Epub 2014 Aug 28.

University Hospitals Southampton NHS Foundation Trust, Southampton, United Kingdom; Clinical and Experimental Sciences, University of Southampton, Southampton, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2014.07.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186905PMC
October 2014

Identifying the heterogeneity of young adult rhinitis through cluster analysis in the Isle of Wight birth cohort.

J Allergy Clin Immunol 2015 Jan 29;135(1):143-50. Epub 2014 Jul 29.

David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, United Kingdom; Clinical and Experimental Medicine, Faculty of Medicine, University of Southampton, Southampton, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749140086
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http://dx.doi.org/10.1016/j.jaci.2014.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289086PMC
January 2015

The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition.

Clin Epigenetics 2014 15;6(1). Epub 2014 Apr 15.

Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, 236A Robison Hall, Memphis, TN 38152, USA.

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http://dx.doi.org/10.1186/1868-7083-6-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023182PMC
May 2014

Effect of GSTM2-5 polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study.

BMC Pulm Med 2013 Sep 3;13:56. Epub 2013 Sep 3.

Division of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, 236A Robison Hall, Memphis, TN 38152, USA.

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http://dx.doi.org/10.1186/1471-2466-13-56DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3846453PMC
September 2013

The methylation of the LEPR/LEPROT genotype at the promoter and body regions influence concentrations of leptin in girls and BMI at age 18 years if their mother smoked during pregnancy.

Int J Mol Epidemiol Genet 2013 25;4(2):86-100. Epub 2013 Jun 25.

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina Columbia, SC, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709113PMC
July 2013

Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study.

BMC Med Genet 2013 Jul 2;14:67. Epub 2013 Jul 2.

Department of Epidemiology and Biostatistics, Norman J. Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, USA.

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http://dx.doi.org/10.1186/1471-2350-14-67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700873PMC
July 2013

The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years.

Clin Epigenetics 2013 Jan 3;5(1). Epub 2013 Jan 3.

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, 800 Sumter Street, Columbia, SC, 29208, USA.

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http://dx.doi.org/10.1186/1868-7083-5-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544634PMC
January 2013

IL-36α exerts pro-inflammatory effects in the lungs of mice.

PLoS One 2012 20;7(9):e45784. Epub 2012 Sep 20.

Center for Immunology and Inflammatory Diseases, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045784PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447790PMC
February 2013

Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.

PLoS One 2012 5;7(3):e32721. Epub 2012 Mar 5.

Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0032721PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293849PMC
July 2012

What does adolescent undiagnosed wheeze represent? Findings from the Isle of Wight Cohort.

Eur Respir J 2012 Sep 20;40(3):580-8. Epub 2012 Jan 20.

The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, UK.

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http://dx.doi.org/10.1183/09031936.00085111DOI Listing
September 2012

Characterisation of asthma that develops during adolescence; findings from the Isle of Wight Birth Cohort.

Respir Med 2012 Mar 31;106(3):329-37. Epub 2011 Dec 31.

The David Hide Asthma and Allergy Research Centre, St Mary's Hospital, Newport, Isle of Wight, PO30 5TG, United Kingdom.

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http://dx.doi.org/10.1016/j.rmed.2011.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260349PMC
March 2012

Targeted analysis of four breeds narrows equine Multiple Congenital Ocular Anomalies locus to 208 kilobases.

Mamm Genome 2011 Jun 5;22(5-6):353-60. Epub 2011 Apr 5.

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Undervisningsplan 4A, PO Box 7023, 750 07 Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00335-011-9325-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098992PMC
June 2011

Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study.

Allergy Asthma Clin Immunol 2010 Apr 20;6(1). Epub 2010 Apr 20.

Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, USA.

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http://dx.doi.org/10.1186/1710-1492-6-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874524PMC
April 2010

Interleukin-1 family member 9 stimulates chemokine production and neutrophil influx in mouse lungs.

Am J Respir Cell Mol Biol 2011 Feb 18;44(2):134-45. Epub 2010 Mar 18.

Department of Pediatrics, University of Florida, Gainesville, USA.

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http://dx.doi.org/10.1165/rcmb.2009-0315OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049228PMC
February 2011

Equine Multiple Congenital Ocular Anomalies maps to a 4.9 megabase interval on horse chromosome 6.

BMC Genet 2008 Dec 19;9:88. Epub 2008 Dec 19.

Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, Sweden.

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http://dx.doi.org/10.1186/1471-2156-9-88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2653074PMC
December 2008

Long-term effects of breastfeeding, maternal smoking during pregnancy, and recurrent lower respiratory tract infections on asthma in children.

J Asthma 2008 Oct;45(8):688-95

Department of Epidemiology and Biostatistics, Norman J Arnold School of Public Health, University of South Carolina, Columbia, SC 29208-0001, USA.

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http://dx.doi.org/10.1080/02770900802178306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700345PMC
October 2008

Patterns of GATA3 and IL13 gene polymorphisms associated with childhood rhinitis and atopy in a birth cohort.

J Allergy Clin Immunol 2008 Feb 26;121(2):408-14. Epub 2007 Nov 26.

Department of Statistics and Probability, Michigan State University, East Lansing, MI 48823, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009167490701778
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http://dx.doi.org/10.1016/j.jaci.2007.09.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705662PMC
February 2008

IL13 gene polymorphism association with cord serum immunoglobulin E.

Pediatr Allergy Immunol 2007 Jun 7;18(4):288-92. Epub 2007 Mar 7.

Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina, USA.

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http://dx.doi.org/10.1111/j.1399-3038.2006.00524.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366045PMC
June 2007

Elevated amount of Toll-like receptor 4 mRNA in bronchial epithelial cells is associated with airway inflammation in horses with recurrent airway obstruction.

Am J Physiol Lung Cell Mol Physiol 2007 Apr 8;292(4):L936-43. Epub 2006 Dec 8.

Pulmonary Laboratory, Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1152/ajplung.00394.2006DOI Listing
April 2007

IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma.

Immunogenetics 2006 Oct 5;58(10):851-5. Epub 2006 Oct 5.

Comparative Medicine and Integrative Biology Program, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA.

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http://dx.doi.org/10.1007/s00251-006-0146-xDOI Listing
October 2006

Time to draw breath: asthma-susceptibility genes are identified.

Nat Rev Genet 2004 May;5(5):376-87

Division of Immunobiology, Cincinnati Children's Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.

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http://www.nature.com/articles/nrg1326
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http://dx.doi.org/10.1038/nrg1326DOI Listing
May 2004