Susan Engelbrecht

Susan Engelbrecht

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Susan Engelbrecht

Publications by authors named "Susan Engelbrecht"

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Near full-length HIV-1 subtype B sequences from the early South African epidemic, detecting a BD unique recombinant form (URF) from a sample in 1985.

Sci Rep 2019 Apr 17;9(1):6227. Epub 2019 Apr 17.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, PO Box 241, Cape Town, 8000, South Africa.

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http://www.nature.com/articles/s41598-019-42417-1
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http://dx.doi.org/10.1038/s41598-019-42417-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470202PMC
April 2019

The effect of interventions on the transmission and spread of HIV in South Africa: a phylodynamic analysis.

Sci Rep 2019 Feb 25;9(1):2640. Epub 2019 Feb 25.

Emerging Pathogens Institute, University of Florida, Gainesville, Florida, 32608, United States of America.

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http://dx.doi.org/10.1038/s41598-018-37749-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389914PMC
February 2019

Viruses as indicators of contemporary host dispersal and phylogeography: an example of feline immunodeficiency virus (FIV ) in free-ranging African lion (Panthera leo).

J Evol Biol 2018 Oct 25;31(10):1529-1543. Epub 2018 Jul 25.

Evolutionary Genomics Group, Department of Botany and Zoology, Faculty of Science, Stellenbosch University, Stellenbosch, South Africa.

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http://dx.doi.org/10.1111/jeb.13348DOI Listing
October 2018

Author Correction: Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa.

Sci Rep 2018 Apr 16;8(1):6262. Epub 2018 Apr 16.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-018-24183-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902626PMC
April 2018

Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and available of integrase inhibitors in Cape Town, South Africa.

Sci Rep 2018 Mar 16;8(1):4709. Epub 2018 Mar 16.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-018-22914-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856838PMC
March 2018

Trends in Genotypic HIV-1 Antiretroviral Resistance between 2006 and 2012 in South African Patients Receiving First- and Second-Line Antiretroviral Treatment Regimens.

PLoS One 2013 26;8(6):e67188. Epub 2013 Jun 26.

National Health Laboratory Service, Tygerberg, Coastal Branch, South Africa ; Division of Medical Virology, Stellenbosch University, Faculty of Medicine and Health Sciences, Parow, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067188PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694021PMC
October 2017

Clinical Relevance of Total HIV DNA in Peripheral Blood Mononuclear Cell Compartments as a Biomarker of HIV-Associated Neurocognitive Disorders (HAND).

Viruses 2017 10 31;9(11). Epub 2017 Oct 31.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Francie van Zijl Avenue, P.O. Box 241, Cape Town 8000, South Africa.

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http://dx.doi.org/10.3390/v9110324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5707531PMC
October 2017

Analysis of Viral Diversity in Relation to the Recency of HIV-1C Infection in Botswana.

PLoS One 2016 23;11(8):e0160649. Epub 2016 Aug 23.

Wellcome Trust Africa Centre for Health and Population Studies, Dorris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994946PMC
July 2017

Pairwise diversity and tMRCA as potential markers for HIV infection recency.

Medicine (Baltimore) 2017 Feb;96(6):e6041

aDivision of Medical Virology, Stellenbosch University, Tygerberg, South Africa bBotswana-Harvard AIDS Institute Partnership, Gaborone, Botswana cAfrica Health Research Institute, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, Republic of South Africa dHarvard T.H. Chan School of Public Health, Boston, MA, USA eNational Health Laboratory Services (NHLS), Tygerberg Coastal, South Africa fResearch Department of Infection, University College London, London, United Kingdom gCollege of Health Sciences, University of KwaZulu-Natal, Durban, Republic of South Africa hDivision of Sleep Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1097/MD.0000000000006041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313003PMC
February 2017

Origin, imports and exports of HIV-1 subtype C in South Africa: A historical perspective.

Infect Genet Evol 2016 12 12;46:200-208. Epub 2016 Jul 12.

Africa Centre for Population Health, University of KwaZulu-Natal, Durban 4041, South Africa; College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa; Research Department of Infection, University College London, London WC1E 6BT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.meegid.2016.07.008DOI Listing
December 2016

Mutational Heterogeneity in p6 Gag Late Assembly (L) Domains in HIV-1 Subtype C Viruses from South Africa.

AIDS Res Hum Retroviruses 2016 Jan 9;32(1):80-4. Epub 2015 Oct 9.

1 Department of Laboratory Medicine, Division of Clinical Microbiology, Karolinska Institutet , Stockholm, Sweden .

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http://dx.doi.org/10.1089/AID.2015.0266DOI Listing
January 2016

History and origin of the HIV-1 subtype C epidemic in South Africa and the greater southern African region.

Sci Rep 2015 Nov 17;5:16897. Epub 2015 Nov 17.

Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, KwaZulu-Natal, South Africa.

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http://dx.doi.org/10.1038/srep16897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648088PMC
November 2015

Identifying Recent HIV Infections: From Serological Assays to Genomics.

Viruses 2015 Oct 23;7(10):5508-24. Epub 2015 Oct 23.

Africa Centre for Health and Population Studies, Doris Duke Medical Research Centre, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban 4041, South Africa.

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http://dx.doi.org/10.3390/v7102887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632395PMC
October 2015

Detection of transmission clusters of HIV-1 subtype C over a 21-year period in Cape Town, South Africa.

PLoS One 2014 30;9(10):e109296. Epub 2014 Oct 30.

Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, KwaZulu-Natal, South Africa; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, KwaZulu-Natal, South Africa; Research Department of Infection, University College of London, London, the United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0109296PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214637PMC
June 2015

Sequencing and phylogenetic analysis of near full-length HIV-1 subtypes A, B, G and unique recombinant AC and AD viral strains identified in South Africa.

AIDS Res Hum Retroviruses 2015 Apr 21;31(4):412-20. Epub 2015 Jan 21.

1 Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University , Tygerberg Academic Hospital, Tygerberg, Cape Town, South Africa .

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http://dx.doi.org/10.1089/AID.2014.0230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378615PMC
April 2015

HIV-1 subtypes B and C unique recombinant forms (URFs) and transmitted drug resistance identified in the Western Cape Province, South Africa.

PLoS One 2014 7;9(6):e90845. Epub 2014 Mar 7.

Division of Medical Virology, Stellenbosch University, Tygerberg, South Africa; National Health Laboratory Services (NHLS), Tygerberg Coastal, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090845PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946584PMC
February 2015

High HIV, HPV, and STI prevalence among young Western Cape, South African women: EVRI HIV prevention preparedness trial.

J Acquir Immune Defic Syndr 2015 Feb;68(2):227-35

*Center for Infection Research in Cancer, Moffitt Cancer Center, Tampa, FL; †Department of Obstetrics and Gynaecology and Unit for Gynaecological Oncology, Tygerberg Hospital, Stellenbosch University, Cape Town, South Africa; ‡Department of Medicine and Centre for Infectious Diseases, Stellenbosch University, Cape Town, South Africa; §Division of Medical Virology, Stellenbosch University and NHLS Tygerberg, Cape Town, South Africa; ‖Department of Research, Cluster Infectious Diseases, Public Health Service of Amsterdam, Amsterdam, the Netherlands; ¶Department of Internal Medicine, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Amsterdam, the Netherlands; and #FHI 360, Durham, NC.

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http://dx.doi.org/10.1097/QAI.0000000000000425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4378717PMC
February 2015

HIV-1 diversity in an antiretroviral treatment naïve cohort from Bushbuckridge, Mpumalanga Province, South Africa.

Virol J 2015 Feb 13;12:24. Epub 2015 Feb 13.

Division of Medical Virology, Department of Pathology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg Hospital, P.O. Box 241, Cape Town, 8000, South Africa.

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http://dx.doi.org/10.1186/s12985-015-0244-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340098PMC
February 2015

Combination antiretroviral therapy reduces the detection risk of cervical human papilloma virus infection in women living with HIV.

AIDS 2015 Jan;29(1):59-66

aDepartment of Medicine and Centre for Infectious Diseases (CID) bDepartment of Obstetrics and Gynecology cDepartment of Pathology, Division of Medical Virology, Stellenbosch University, Faculty of Health Sciences dNational Health Laboratory Services (NHLS), Western Cape Region, Tygerberg Hospital (Coastal) eDepartment of Interdisciplinary Health Sciences, Centre for Evidence-Based Healthcare, Biostatistics Unit, Stellenbosch University, Faculty of Health Sciences, Cape Town, South Africa fDepartment of Epidemiology, Pittsburgh Graduate School of Public Health, Infectious Diseases Epidemiology Research Program, Pittsburgh, Pennsylvania gDepartments of Epidemiology and International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000512DOI Listing
January 2015

Impact of the HIV Tat C30C31S dicysteine substitution on neuropsychological function in patients with clade C disease.

J Neurovirol 2014 Dec 1;20(6):627-35. Epub 2014 Nov 1.

Department of Psychology and Behavioral Neuroscience, University of Missouri-St. Louis, University Boulevard, St. Louis, USA,

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http://dx.doi.org/10.1007/s13365-014-0293-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268069PMC
December 2014

Construction of a high titer infectious HIV-1 subtype C proviral clone from South Africa.

Viruses 2012 09 24;4(9):1830-43. Epub 2012 Sep 24.

Institut für Virologie und Immunbiologie, Universität Würzburg, Versbacher Straße 7, 97078 Würzburg, Germany.

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http://dx.doi.org/10.3390/v4091830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499832PMC
September 2012

Molecular characterization of HIV type 1 among HIV-infected respondents in a cohort being prepared for HIV Phase III vaccine clinical trials, Western Kenya.

AIDS Res Hum Retroviruses 2011 Mar 15;27(3):257-64. Epub 2010 Oct 15.

Kenyatta University, Department of Biological Sciences, Nairobi, Kenya.

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http://www.liebertpub.com/doi/10.1089/aid.2010.0061
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http://dx.doi.org/10.1089/aid.2010.0061DOI Listing
March 2011

Functional integrity of naturally occurring mutants of HIV-1 subtype C Vpr.

Virus Res 2010 Nov 27;153(2):288-98. Epub 2010 Aug 27.

Division of Medical Virology, Department of Pathology, University of Stellenbosch, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1016/j.virusres.2010.08.020DOI Listing
November 2010

Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif.

Arch Virol 2009 12;154(10):1579-88. Epub 2009 Aug 12.

Division of Medical Virology, Department of Pathology, University of Stellenbosch, Tygerberg Campus, Tygerberg, South Africa.

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http://dx.doi.org/10.1007/s00705-009-0481-yDOI Listing
February 2010

Functions of Tat: the versatile protein of human immunodeficiency virus type 1.

J Gen Virol 2010 Jan 7;91(Pt 1):1-12. Epub 2009 Oct 7.

Division of Medical Virology, Department of Pathology, University of Stellenbosch, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1099/vir.0.016303-0DOI Listing
January 2010

Molecular characterization of non-subtype C and recombinant HIV-1 viruses from Cape Town, South Africa.

Infect Genet Evol 2009 Sep 14;9(5):840-6. Epub 2009 May 14.

Division of Medical Virology, National Health Laboratory Services and University of Stellenbosch, Tygerberg 7505, South Africa.

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http://www.bioafrica.net/manuscripts/Wilkinson_HIV_CapeTown2
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http://linkinghub.elsevier.com/retrieve/pii/S156713480900091
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http://dx.doi.org/10.1016/j.meegid.2009.05.001DOI Listing
September 2009

Human immunodeficiency virus type 1 Vpr: functions and molecular interactions.

J Gen Virol 2009 Aug 20;90(Pt 8):1795-805. Epub 2009 May 20.

Department of Pathology, University of Stellenbosch, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1099/vir.0.011726-0DOI Listing
August 2009

Molecular and phylogenetic analysis of HIV type 1 vpr sequences of South African strains.

AIDS Res Hum Retroviruses 2009 Mar;25(3):357-62

Department of Pathology, Division of Medical Virology, University of Stellenbosch, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1089/aid.2008.0251DOI Listing
March 2009

Molecular analysis of HIV type 1 vif sequences from Cape Town, South Africa.

AIDS Res Hum Retroviruses 2008 Jul;24(7):991-4

Division of Medical Virology, National Health Laboratory Service (NHLS) and University of Stellenbosch, Tygerberg 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1089/aid.2008.0077DOI Listing
July 2008

Phylogenetic diversity and low level antiretroviral resistance mutations in HIV type 1 treatment-naive patients from Cape Town, South Africa.

AIDS Res Hum Retroviruses 2008 Jul;24(7):1009-12

Division of Medical Virology, National Health Laboratory Service (NHLS) and University of Stellenbosch, Tygerberg 7505, Cape Town, South Africa.

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http://dx.doi.org/10.1089/aid.2008.0028DOI Listing
July 2008

Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa.

AIDS Res Hum Retroviruses 2007 Dec;23(12):1575-8

Department of Medical Virology, National health Laboratory Service (NHLS) and University of Stellenbosch, Tygerberg Academic Hospital, Tygerberg 7505, South Africa.

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http://www.liebertpub.com/doi/10.1089/aid.2007.0167
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http://dx.doi.org/10.1089/aid.2007.0167DOI Listing
December 2007

HPV detection in primary intra-oral squamous cell carcinomas--commensal, aetiological agent or contamination?

J Oral Pathol Med 2006 Feb;35(2):86-90

Department of Oral Pathology and Oral Biology, University of Pretoria, Pretoria, South Africa.

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http://dx.doi.org/10.1111/j.1600-0714.2006.00385.xDOI Listing
February 2006

Sequence analysis of near full-length HIV type 1 subtype D primary strains isolated in Cape Town, South Africa, from 1984 to 1986.

AIDS Res Hum Retroviruses 2005 May;21(5):410-3

Department of Medical Virology, National Health Laboratory Service (NHLS) and University of Stellenbosch, Tygerberg Academic Hospital, Tygerberg, 7505, South Africa.

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http://dx.doi.org/10.1089/aid.2005.21.410DOI Listing
May 2005

Mapping sites of positive selection and amino acid diversification in the HIV genome: an alternative approach to vaccine design?

Genetics 2004 Jul;167(3):1047-58

HIV Molecular Virology and Bioinformatics Laboratory, Africa Centre for Health and Population Studies, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4013, South Africa.

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http://dx.doi.org/10.1534/genetics.103.018135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470929PMC
July 2004

Variability at human immunodeficiency virus type 1 subtype C protease cleavage sites: an indication of viral fitness?

J Virol 2003 Sep;77(17):9422-30

HIV-1 Molecular Virology and Bioinformatics Unit, Africa Centre for Health and Population Studies, and the Nelson R. Mandela School of Medicine, University of Natal, Durban, South Africa.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC187406PMC
http://dx.doi.org/10.1128/jvi.77.17.9422-9430.2003DOI Listing
September 2003

Change in co-receptor usage of current South African HIV-1 subtype C primary isolates.

AIDS 2002 Dec;16(18):2479-80

Department of Medical Virology, Faculty of Health Sciences, University of Stellenbosch and Tygerberg Hospital, Tygerberg, South Africa.

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http://dx.doi.org/10.1097/01.aids.0000042582.93174.dfDOI Listing
December 2002

Novel evolutionary analyses of full-length HIV type 1 subtype C molecular clones from Cape Town, South Africa.

AIDS Res Hum Retroviruses 2002 Nov;18(17):1327-32

Vaccines Research, Chiron Corporation, Emeryville, California 94608, USA.

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http://dx.doi.org/10.1089/088922202320886370DOI Listing
November 2002

Genotypic and phenotypic analysis of the env gene from South African HIV-1 subtype B and C isolates.

J Med Virol 2002 Oct;68(2):141-6

Department of Medical Virology, University of Stellenbosch and Tygerberg Hospital, Tygerberg, South Africa.

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http://dx.doi.org/10.1002/jmv.10199DOI Listing
October 2002

HHV-8 subtypes in South Africa: identification of a case suggesting a novel B variant.

J Med Virol 2002 Feb;66(2):235-40

Department of Medical Virology, University of Stellenbosch, Tygerberg, South Africa.

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February 2002

Characterization of the South African HIV type 1 subtype C complete 5' long terminal repeat, nef, and regulatory genes.

AIDS Res Hum Retroviruses 2002 Jan;18(2):149-59

Department of Medical Virology, University of Stellenbosch, Tygerberg 7505, South Africa.

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http://dx.doi.org/10.1089/08892220252779692DOI Listing
January 2002