Publications by authors named "Susan E Wert"

70Publications

Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung.

J Biomed Semantics 2019 10 24;10(1):18. Epub 2019 Oct 24.

Department of Pediatrics, Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center/Research Foundation, University of Cincinnati College of Medicine, 3333 Burnet Ave, MLC7029, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1186/s13326-019-0209-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814058PMC
October 2019

Diseases of pulmonary surfactant homeostasis.

Annu Rev Pathol 2015 ;10:371-93

Divisions of Neonatology, Perinatal Biology, and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229; email: , ,

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http://dx.doi.org/10.1146/annurev-pathol-012513-104644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316199PMC
June 2015

A Molecular atlas of Xenopus respiratory system development.

Dev Dyn 2015 Jan 11;244(1):69-85. Epub 2014 Sep 11.

Division of Developmental Biology, Perinatal Institute, Cincinnati Children's Hospital, and the Department of Pediatrics, College of Medicine University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/dvdy.24180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276498PMC
January 2015

Genotype-phenotype correlations for infants and children with ABCA3 deficiency.

Am J Respir Crit Care Med 2014 Jun;189(12):1538-43

1 Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.

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http://dx.doi.org/10.1164/rccm.201402-0342OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226019PMC
June 2014

Sox17 is required for normal pulmonary vascular morphogenesis.

Dev Biol 2014 Mar 10;387(1):109-20. Epub 2014 Jan 10.

Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, The University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2013.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422074PMC
March 2014

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

Dev Biol 2013 Mar 22;375(2):128-39. Epub 2012 Dec 22.

Perinatal Institute, Divisions of Neonatology-Perinatal-Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00121606120067
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http://dx.doi.org/10.1016/j.ydbio.2012.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582784PMC
March 2013

CDC42 is required for structural patterning of the lung during development.

Dev Biol 2013 Feb 5;374(1):46-57. Epub 2012 Dec 5.

Key Laboratory of Obstetric, Gynecologic and Pediatric Diseases and Birth Defects of the Ministry of Education, West China Institute of Women and Children's Health, and Department of Pediatrics, Huaxi Second University Hospital, Sichuan University, No. 17, Section 3, South Renming Rd., Chengdu, Sichuan 610041, PR China.

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http://dx.doi.org/10.1016/j.ydbio.2012.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549046PMC
February 2013

Transcriptional programs controlling perinatal lung maturation.

PLoS One 2012 20;7(8):e37046. Epub 2012 Aug 20.

The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037046PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423373PMC
May 2013

Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways.

Dev Biol 2012 Oct 2;370(2):198-212. Epub 2012 Aug 2.

Division of Pulmonary Biology, Cincinnati Children's Hospital Research Foundation, 3333 Burnet Ave., Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.ydbio.2012.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3449302PMC
October 2012

Activation of sterol-response element-binding proteins (SREBP) in alveolar type II cells enhances lipogenesis causing pulmonary lipotoxicity.

J Biol Chem 2012 Mar 20;287(13):10099-114. Epub 2012 Jan 20.

Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://www.uphs.upenn.edu/ifem/ins/documents/(9-12-12)%20Bat
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http://www.jbc.org/cgi/doi/10.1074/jbc.M111.303669
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http://dx.doi.org/10.1074/jbc.M111.303669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323060PMC
March 2012

Maternal synchronization of gestational length and lung maturation.

PLoS One 2011 9;6(11):e26682. Epub 2011 Nov 9.

The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, the Department of Pediatrics and The University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026682PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212521PMC
April 2012

Pulmonary nodules in a newborn with ATP-binding cassette transporter A3 (ABCA3) mutations.

Pediatrics 2011 May 4;127(5):e1347-51. Epub 2011 Apr 4.

Division of Pediatric Pulmonology, University of Utah School of Medicine, Primary Children's Medical Center, 100 N Mario Capecchi Dr, Salt Lake City, UT 84113-1100, USA.

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http://dx.doi.org/10.1542/peds.2010-1477DOI Listing
May 2011

Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis.

Thorax 2011 Aug 21;66(8):651-7. Epub 2011 Mar 21.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Perinatal Institute, MLC7029, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://thorax.bmj.com/cgi/doi/10.1136/thx.2010.151555
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http://dx.doi.org/10.1136/thx.2010.151555DOI Listing
August 2011

A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.

J Allergy Clin Immunol 2011 Jan 3;127(1):254-61, 261.e1-6. Epub 2010 Dec 3.

Division of Asthma Research, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1016/j.jaci.2010.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058372PMC
January 2011

Sox2 activates cell proliferation and differentiation in the respiratory epithelium.

Am J Respir Cell Mol Biol 2011 Jul 20;45(1):101-10. Epub 2010 Sep 20.

Cincinnati Children's Hospital Medical Center, Division of Pulmonary Biology, MLC 7029, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1165/rcmb.2010-0149OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145063PMC
July 2011

Fatal familial lung disease caused by ABCA3 deficiency without identified ABCA3 mutations.

J Pediatr 2010 Jul 20;157(1):62-8. Epub 2010 Mar 20.

Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD 21287-2533, USA.

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http://dx.doi.org/10.1016/j.jpeds.2010.01.010DOI Listing
July 2010

Conditional deletion of Abca3 in alveolar type II cells alters surfactant homeostasis in newborn and adult mice.

Am J Physiol Lung Cell Mol Physiol 2010 May 26;298(5):L646-59. Epub 2010 Feb 26.

The Perinatal Institute and Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics and University of Cincinnati College of Medicine, Ohio.

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http://dx.doi.org/10.1152/ajplung.00409.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867401PMC
May 2010

Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.

PLoS One 2009 Dec 14;4(12):e8248. Epub 2009 Dec 14.

Division of Pulmonary Biology in the Perinatal Institute , Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008248PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2788414PMC
December 2009

Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus.

Dev Biol 2009 Dec 14;336(2):266-79. Epub 2009 Oct 14.

Divisions of Pulmonary Biology, Perinatal Institute of the Cincinnati Children's Hospital Research Foundation, 3333 Burnet Ave., Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.ydbio.2009.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783468PMC
December 2009

Alveolar surfactant homeostasis and the pathogenesis of pulmonary disease.

Annu Rev Med 2010 ;61:105-19

Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1146/annurev.med.60.041807.123500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127631PMC
May 2010

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.

J Clin Invest 2009 Oct 14;119(10):2914-24. Epub 2009 Sep 14.

The Perinatal Institute, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati School of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1172/JCI39731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752084PMC
October 2009

Genetic disorders of surfactant dysfunction.

Pediatr Dev Pathol 2009 Jul-Aug;12(4):253-74

Perinatal Institute, Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, and the Department of Pediatrics, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.2350/09-01-0586.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987676PMC
November 2009

Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts.

J Biol Chem 2009 Feb 11;284(6):4018-30. Epub 2008 Dec 11.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, the University of Cincinnati College of Medicine, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1074/jbc.M805388200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635058PMC
February 2009

Forkhead Box m1 transcription factor is required for perinatal lung function.

Proc Natl Acad Sci U S A 2008 Dec 25;105(49):19330-5. Epub 2008 Nov 25.

Division of Pulmonary Biology, Cincinnati Children's Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1073/pnas.0806748105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587228PMC
December 2008

Kruppel-like factor 5 is required for perinatal lung morphogenesis and function.

Development 2008 Aug 3;135(15):2563-72. Epub 2008 Jul 3.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1242/dev.021964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459582PMC
August 2008

Does adiponectin play a role in pulmonary emphysema?

Authors:
Susan E Wert

Am J Physiol Lung Cell Mol Physiol 2008 Jun 18;294(6):L1032-4. Epub 2008 Apr 18.

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http://dx.doi.org/10.1152/ajplung.90273.2008DOI Listing
June 2008

R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis.

Development 2008 Mar 6;135(6):1049-58. Epub 2008 Feb 6.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center and The University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1242/dev.013359DOI Listing
March 2008

STAT3 regulates ABCA3 expression and influences lamellar body formation in alveolar type II cells.

Am J Respir Cell Mol Biol 2008 May 20;38(5):551-8. Epub 2007 Dec 20.

Cincinnati Children's Hospital Medical Center, Section of Neonatology, Perinatal and Pulmonary Biology, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1165/rcmb.2007-0311OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2335336PMC
May 2008

Conditional deletion of Pten causes bronchiolar hyperplasia.

Am J Respir Cell Mol Biol 2008 Mar 5;38(3):337-45. Epub 2007 Oct 5.

Division of Pulmonary Biology, 4403, Cincinnati Children's Hospital Research Foundation, University of Cincinnati Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1165/rcmb.2007-0182OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258453PMC
March 2008

SPDEF regulates goblet cell hyperplasia in the airway epithelium.

J Clin Invest 2007 Apr 8;117(4):978-88. Epub 2007 Mar 8.

Division of Pulmonary Biology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1172/JCI29176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1810569PMC
April 2007

GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis.

N Engl J Med 2007 Feb;356(6):567-79

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1056/NEJMoa062505DOI Listing
February 2007

ABCA3 deficiency: neonatal respiratory failure and interstitial lung disease.

Semin Perinatol 2006 Dec;30(6):327-34

Division of Neonatology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01460005050010
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http://dx.doi.org/10.1053/j.semperi.2005.12.001DOI Listing
December 2006

Persistent tachypnea and hypoxia in a 3-month-old term infant.

J Pediatr 2006 Nov;149(5):702-706

Department of Pediatrics, Division of Pulmonary Medicine, Northwestern University Feinberg School of Medicine, Children's Memorial Hospital, Chicago, IL 60614, USA.

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http://dx.doi.org/10.1016/j.jpeds.2006.07.032DOI Listing
November 2006

Calcineurin/Nfat signaling is required for perinatal lung maturation and function.

J Clin Invest 2006 Oct 21;116(10):2597-609. Epub 2006 Sep 21.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1172/JCI27331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570374PMC
October 2006

Expression of ABCA3 in developing lung and other tissues.

J Histochem Cytochem 2007 Jan 18;55(1):71-83. Epub 2006 Sep 18.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1369/jhc.6A6962.2006DOI Listing
January 2007

Stat3 is required for cytoprotection of the respiratory epithelium during adenoviral infection.

J Immunol 2006 Jul;177(1):527-37

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.4049/jimmunol.177.1.527DOI Listing
July 2006

Sox17 influences the differentiation of respiratory epithelial cells.

Dev Biol 2006 Jun 30;294(1):192-202. Epub 2006 Mar 30.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1016/j.ydbio.2006.02.038DOI Listing
June 2006

Transdifferentiation of ciliated cells during repair of the respiratory epithelium.

Am J Respir Cell Mol Biol 2006 Feb 20;34(2):151-7. Epub 2005 Oct 20.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0332OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2644179PMC
February 2006

Conditional recombination reveals distinct subsets of epithelial cells in trachea, bronchi, and alveoli.

Am J Respir Cell Mol Biol 2005 Nov 29;33(5):455-62. Epub 2005 Jul 29.

Division of Pulmonary Biology and Neonatology, Cincinnati Children's Hospital Medical Center, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1165/rcmb.2005-0180OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715353PMC
November 2005

Beta-catenin regulates differentiation of respiratory epithelial cells in vivo.

Am J Physiol Lung Cell Mol Physiol 2005 Dec 22;289(6):L971-9. Epub 2005 Jul 22.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1152/ajplung.00172.2005DOI Listing
December 2005

Genetic disorders of surfactant homeostasis.

Biol Neonate 2005 1;87(4):283-7. Epub 2005 Jun 1.

Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children's Hospital Medical Center, The University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1159/000084875DOI Listing
August 2005

ABCA3 mutations associated with pediatric interstitial lung disease.

Am J Respir Crit Care Med 2005 Oct 23;172(8):1026-31. Epub 2005 Jun 23.

Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1164/rccm.200503-504OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403838PMC
October 2005

A common mutation in the surfactant protein C gene associated with lung disease.

J Pediatr 2005 Mar;146(3):370-5

Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002234760400966
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http://dx.doi.org/10.1016/j.jpeds.2004.10.028DOI Listing
March 2005

Partial SP-B deficiency perturbs lung function and causes air space abnormalities.

Am J Physiol Lung Cell Mol Physiol 2005 Jun 18;288(6):L1154-61. Epub 2005 Feb 18.

Cincinnati Children's Hospital Medical Center, Division of Neonatology, 3333 Burnet Ave., Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1152/ajplung.00392.2004DOI Listing
June 2005

Interleukin-1beta causes pulmonary inflammation, emphysema, and airway remodeling in the adult murine lung.

Am J Respir Cell Mol Biol 2005 Apr 24;32(4):311-8. Epub 2005 Jan 24.

Goteborg University, Department of Pediatrics, The Queen Silvia Children's Hospital, 41685 Goteborg, Sweden.

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http://dx.doi.org/10.1165/rcmb.2004-0309OCDOI Listing
April 2005

Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.

Gene Expr Patterns 2004 Dec;5(2):193-208

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.

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http://dx.doi.org/10.1016/j.modgep.2004.08.006DOI Listing
December 2004

Genetic disorders influencing lung formation and function at birth.

Hum Mol Genet 2004 Oct;13 Spec No 2:R207-15

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddh252DOI Listing
October 2004

Role of Sonic hedgehog in patterning of tracheal-bronchial cartilage and the peripheral lung.

Dev Dyn 2004 Sep;231(1):57-71

Department of Pediatrics, Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1002/dvdy.20105DOI Listing
September 2004

ABCA3 gene mutations in newborns with fatal surfactant deficiency.

N Engl J Med 2004 Mar;350(13):1296-303

Human Genetics Section, Laboratory of Genomic Diversity, National Cancer Institute - Frederick, Frederick, Md, USA.

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http://www.uphs.upenn.edu/ifem/ins/feinstein-ABCA3.pdf
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http://www.nejm.org/doi/abs/10.1056/NEJMoa032178
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http://dx.doi.org/10.1056/NEJMoa032178DOI Listing
March 2004

Stat-3 is required for pulmonary homeostasis during hyperoxia.

J Clin Invest 2004 Jan;113(1):28-37

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1172/JCI19491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC300770PMC
January 2004

Progressive lung disease and surfactant dysfunction with a deletion in surfactant protein C gene.

Am J Respir Cell Mol Biol 2004 Jun 4;30(6):771-6. Epub 2003 Dec 4.

Division of Newborn Medicine, Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine and St. Louis Children's Hospital, 1 Children's Place, St. Louis, MO 63110, USA.

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http://www.uphs.upenn.edu/ifem/ins/yu-progressive%20lung%20d
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http://www.atsjournals.org/doi/abs/10.1165/rcmb.2003-0323OC
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http://dx.doi.org/10.1165/rcmb.2003-0323OCDOI Listing
June 2004

Expression of a human surfactant protein C mutation associated with interstitial lung disease disrupts lung development in transgenic mice.

J Biol Chem 2003 Dec 2;278(52):52739-46. Epub 2003 Oct 2.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1074/jbc.M309599200DOI Listing
December 2003

Pulmonary surfactant protein A, B, and C mRNA and protein expression in the nitrofen-induced congenital diaphragmatic hernia rat model.

Pediatr Res 2003 Nov 6;54(5):641-52. Epub 2003 Aug 6.

Department of Surgery, Sophia Children's Hospital, Erasmus Medical Center Rotterdam, 3015 GJ Rotterdam, The Netherlands.

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http://dx.doi.org/10.1203/01.PDR.0000086906.19683.42DOI Listing
November 2003

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.

J Biol Chem 2003 Oct 28;278(41):40231-8. Epub 2003 Jul 28.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1074/jbc.M305892200DOI Listing
October 2003

Early restriction of peripheral and proximal cell lineages during formation of the lung.

Proc Natl Acad Sci U S A 2002 Aug 26;99(16):10482-7. Epub 2002 Jul 26.

Cincinnati Children's Hospital Medical Center, Division of Pulmonary Biology, Cincinnati, OH 45229-3039, USA.

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http://dx.doi.org/10.1073/pnas.152238499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC124949PMC
August 2002

Fibroblast growth factor 18 influences proximal programming during lung morphogenesis.

J Biol Chem 2002 Jun 1;277(25):22743-9. Epub 2002 Apr 1.

Division of Pulmonary Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1074/jbc.M202253200DOI Listing
June 2002

Increased expression of thyroid transcription factor-1 (TTF-1) in respiratory epithelial cells inhibits alveolarization and causes pulmonary inflammation.

Dev Biol 2002 Feb;242(2):75-87

Division of Pulmonary Biology, Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039, USA.

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http://dx.doi.org/10.1006/dbio.2001.0540DOI Listing
February 2002