Susan E Quaggin

Susan E Quaggin

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Susan E Quaggin

Publications by authors named "Susan E Quaggin"

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Forward genetic screen in human podocytes identifies diphthamide biosynthesis genes as regulators of adhesion.

Am J Physiol Renal Physiol 2019 Dec 30;317(6):F1593-F1604. Epub 2019 Sep 30.

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1152/ajprenal.00195.2019DOI Listing
December 2019

Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.

Elife 2019 Oct 17;8. Epub 2019 Oct 17.

Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, United States.

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http://dx.doi.org/10.7554/eLife.48474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874417PMC
October 2019

Endothelial ERK1/2 signaling maintains integrity of the quiescent endothelium.

J Exp Med 2019 Aug 13;216(8):1874-1890. Epub 2019 Jun 13.

Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT

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http://dx.doi.org/10.1084/jem.20182151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6683988PMC
August 2019

Genetic Deletion of Does Not Cause Proteinuric Kidney Disease in Mice.

Front Med (Lausanne) 2019 27;6:189. Epub 2019 Aug 27.

Division of Nephrology and Hypertension, Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.

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http://dx.doi.org/10.3389/fmed.2019.00189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718710PMC
August 2019

Morphological Analysis of Schlemm's Canal in Mice.

Methods Mol Biol 2018 ;1846:153-160

Feinberg Cardiovascular and Renal Research Institute, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1007/978-1-4939-8712-2_10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499067PMC
May 2019

A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis.

Epigenetics 2017 6;12(11):1004-1013. Epub 2017 Dec 6.

a Feinberg Cardiovascular Research Institute, Feinberg School of Medicine , Northwestern University , Chicago , Illinois , USA.

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http://dx.doi.org/10.1080/15592294.2017.1370173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788418PMC
December 2018

Selective permeability of mouse blood-aqueous barrier as determined by N-heavy isotope tracing and mass spectrometry.

Proc Natl Acad Sci U S A 2018 09 20;115(36):9032-9037. Epub 2018 Aug 20.

Division of Nephrology and Hypertension, Feinberg Cardiovascular and Renal Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611;

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http://dx.doi.org/10.1073/pnas.1807982115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130361PMC
September 2018

Novel ACE2-Fc chimeric fusion provides long-lasting hypertension control and organ protection in mouse models of systemic renin angiotensin system activation.

Kidney Int 2018 07 22;94(1):114-125. Epub 2018 Apr 22.

Division of Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Feinberg Cardiovascular and Renal Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.01.029DOI Listing
July 2018

Endothelial mineralocorticoid receptor ablation does not alter blood pressure, kidney function or renal vessel contractility.

PLoS One 2018 21;13(2):e0193032. Epub 2018 Feb 21.

Department of Cardiovascular and Renal Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193032PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821352PMC
May 2018

ShcA Adaptor Protein Promotes Nephrin Endocytosis and Is Upregulated in Proteinuric Nephropathies.

J Am Soc Nephrol 2018 01 10;29(1):92-103. Epub 2017 Oct 10.

Department of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada;

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http://dx.doi.org/10.1681/ASN.2017030285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748910PMC
January 2018

Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1.

Am J Physiol Renal Physiol 2017 Dec 23;313(6):F1232-F1242. Epub 2017 Aug 23.

Division of Nephrology and Hypertension and Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois;

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http://dx.doi.org/10.1152/ajprenal.00311.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814644PMC
December 2017

Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model.

Dis Model Mech 2017 12 19;10(12):1503-1515. Epub 2017 Dec 19.

Biocenter Oulu, Laboratory of Developmental Biology, InfoTech Oulu, Center for Cell Matrix Research, Faculty of Biochemistry and Molecular Medicine, Oulu University, FI-90014 Oulu, Finland

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http://dmm.biologists.org/lookup/doi/10.1242/dmm.028332
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http://dx.doi.org/10.1242/dmm.028332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769601PMC
December 2017

SuPAR and FSGS: is the jury still out?

Nat Rev Nephrol 2017 09 31;13(9):593. Epub 2017 Jul 31.

Northwestern University Feinberg School of Medicine, Division of Nephrology &Hypertension, 303 E. Superior Street, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nrneph.2017.109DOI Listing
September 2017

Angiopoietin-1 deficiency increases tumor metastasis in mice.

BMC Cancer 2017 Aug 11;17(1):539. Epub 2017 Aug 11.

Department of Immunology, Genetics and Pathology, Uppsala University, Dag Hammarskjoldsvagen 20, 751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s12885-017-3531-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553747PMC
August 2017

Glomerular disease: A suPAR kidney connection found in the bone marrow.

Nat Rev Nephrol 2017 05 13;13(5):263-264. Epub 2017 Mar 13.

Northwestern University Feinberg School of Medicine, Division of Nephrology &Hypertension, 303 E. Superior St., Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1038/nrneph.2017.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450403PMC
May 2017

Vascular Growth Factors and Glomerular Disease.

Annu Rev Physiol 2016 ;78:437-61

Feinberg Cardiovascular Research Institute and Division of Nephrology and Hypertension, Northwestern University, Chicago, Illinois 60611; email: ,

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http://dx.doi.org/10.1146/annurev-physiol-021115-105412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450387PMC
December 2016

Dysregulation of angiopoietin-1 plays a mechanistic role in the pathogenesis of cerebral malaria.

Sci Transl Med 2016 09;8(358):358ra128

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5S 1A8, Canada. Sandra Rotman Centre for Global Health, University Health Network-Toronto General Hospital, and the Tropical Disease Unit, Department of Medicine, University of Toronto, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1126/scitranslmed.aaf6812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450386PMC
September 2016

Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy.

Diabetologia 2016 Feb 28;59(2):379-89. Epub 2015 Oct 28.

Diabetes Complications Division, Baker IDI Heart & Diabetes Research Institute, PO Box 6492, St Kilda Rd, Melbourne, VIC, 8008, Australia.

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http://dx.doi.org/10.1007/s00125-015-3796-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450410PMC
February 2016

Kindling the Kidney.

Authors:
Susan E Quaggin

N Engl J Med 2016 Jan;374(3):281-3

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http://dx.doi.org/10.1056/NEJMcibr1514351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450415PMC
January 2016

Therapies on the Horizon for Diabetic Kidney Disease.

Curr Diab Rep 2015 Dec;15(12):111

Division of Nephrology and Hypertension, Feinberg School of Medicine, Northwestern University, 303 East Superior Lurie Building, 10th Floor, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1007/s11892-015-0685-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450405PMC
December 2015

ATGme: Open-source web application for rare codon identification and custom DNA sequence optimization.

BMC Bioinformatics 2015 Sep 21;16:303. Epub 2015 Sep 21.

Biocenter Oulu, Laboratory of Developmental Biology, InfoTech Oulu, Center for Cell Matrix Research, Faculty of Biochemistry and Molecular Medicine, University of Oulu, Aapistie 5A, FIN-90220, Oulu, Finland.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12859-015-0743-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578782PMC
September 2015

Tubulovascular cross-talk by vascular endothelial growth factor a maintains peritubular microvasculature in kidney.

J Am Soc Nephrol 2015 May 10;26(5):1027-38. Epub 2014 Nov 10.

The Lunenfeld-Tanenbaum Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada; Feinberg Cardiovascular Research Institute and Division of Nephrology and Hypertension, Northwestern University, Chicago, Illinois;

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http://dx.doi.org/10.1681/ASN.2014010060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413754PMC
May 2015

Crosstalk in glomerular injury and repair.

Curr Opin Nephrol Hypertens 2015 May;24(3):231-8

aDepartment of Cardiovascular and Renal Research, Institute of Molecular medicine, University of Southern Denmark, Odense, Denmark bDepartment of Clinical Cell Biology and Medicine, Chiba University Graduate School of Medicine cDivision of Diabetes, Metabolism, and Endocrinology, Chiba University Hospital, Chiba, Japan dFeinberg Cardiovascular Research Institute and Division of Nephrology and Hypertension, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465999PMC
May 2015

Signaling during Kidney Development.

Cells 2015 Apr 10;4(2):112-32. Epub 2015 Apr 10.

Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, Oulu University, 90014 Oulu, Finland.

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http://dx.doi.org/10.3390/cells4020112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493451PMC
April 2015

Review series: The cell biology of renal filtration.

J Cell Biol 2015 Apr;209(2):199-210

Feinberg School of Medicine, Northwestern University, Chicago, IL 60611.

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http://dx.doi.org/10.1083/jcb.201410017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4411276PMC
April 2015

Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS.

J Am Soc Nephrol 2014 Nov 5;25(11):2459-70. Epub 2014 Jun 5.

The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; Feinberg Cardiovascular Research Institute and Division of Nephrology and Hypertension, Northwestern University, Chicago, Illinois;

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http://dx.doi.org/10.1681/ASN.2013121307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214535PMC
November 2014

The glomerulus: the sphere of influence.

Clin J Am Soc Nephrol 2014 Aug 29;9(8):1461-9. Epub 2014 May 29.

Brown Medical School, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.2215/CJN.09400913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123398PMC
August 2014

Murine Notch1 is required for lymphatic vascular morphogenesis during development.

Dev Dyn 2014 Jul 17;243(7):957-64. Epub 2014 Apr 17.

Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1002/dvdy.24129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062592PMC
July 2014

PAI-1-regulated extracellular proteolysis governs senescence and survival in Klotho mice.

Proc Natl Acad Sci U S A 2014 May 28;111(19):7090-5. Epub 2014 Apr 28.

Department of Medicine andFeinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, Chicago, IL 60611; and

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http://www.pnas.org/cgi/doi/10.1073/pnas.1321942111
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http://dx.doi.org/10.1073/pnas.1321942111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024885PMC
May 2014

Heparin binding VEGF isoforms attenuate hyperoxic embryonic lung growth retardation via a FLK1-neuropilin-1-PKC dependent pathway.

Respir Res 2014 Mar 19;15:32. Epub 2014 Mar 19.

Department of Pediatrics Section of Respiratory Medicine, Yale University School of Medicine, 333 Cedar Street, P,O, Box 208064, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1186/1465-9921-15-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004166PMC
March 2014

Monitoring and modeling treatment of atypical hemolytic uremic syndrome.

Mol Immunol 2013 May 3;54(1):84-8. Epub 2012 Dec 3.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.molimm.2012.10.044DOI Listing
May 2013

GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure.

Nat Med 2013 May 31;19(5):567-75. Epub 2013 Mar 31.

Department of Medicine, Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/nm.3128DOI Listing
May 2013

DGKE and atypical HUS.

Authors:
Susan E Quaggin

Nat Genet 2013 May;45(5):475-6

Division of Nephrology at the Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ng.2622DOI Listing
May 2013

Molecular basis of organ fibrosis: potential therapeutic approaches.

Exp Biol Med (Maywood) 2013 May;238(5):461-81

Feinberg Cardiovascular Research Institute & Division of Nephrology, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1177/1535370213489441DOI Listing
May 2013

Rapid and sensitive MRM-based mass spectrometry approach for systematically exploring ganglioside-protein interactions.

Proteomics 2013 Apr 12;13(8):1334-8. Epub 2013 Mar 12.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/pmic.201200410DOI Listing
April 2013

Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.

J Biol Chem 2013 Mar 17;288(10):6835-48. Epub 2013 Jan 17.

Department of Medicine and Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M112.419101
Publisher Site
http://dx.doi.org/10.1074/jbc.M112.419101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3591594PMC
March 2013

Regulation of hypoxia-inducible factor 2-a is essential for integrity of the glomerular barrier.

Am J Physiol Renal Physiol 2013 Jan 10;304(1):F120-6. Epub 2012 Oct 10.

Institute of Medicine Science, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1152/ajprenal.00416.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543619PMC
January 2013

Vegfa protects the glomerular microvasculature in diabetes.

Diabetes 2012 Nov;61(11):2958-66

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2337/db11-1655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478549PMC
November 2012

Turning a blind eye to anti-VEGF toxicities.

Authors:
Susan E Quaggin

J Clin Invest 2012 Nov 24;122(11):3849-51. Epub 2012 Oct 24.

The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and Division of Nephrology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1172/JCI65509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498935PMC
November 2012

Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart.

Dev Biol 2012 Aug 9;368(2):345-57. Epub 2012 Jun 9.

Division of Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, ML 7020, 240 Albert Sabin Way, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.ydbio.2012.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3414197PMC
August 2012

MTOR regulates autophagic flux in the glomerulus.

Autophagy 2012 Apr 1;8(4):696-8. Epub 2012 Apr 1.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario Canada.

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http://dx.doi.org/10.4161/auto.19386DOI Listing
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V 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Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller 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Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang 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Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

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November 2011

Scar wars: mapping the fate of epithelial-mesenchymal-myofibroblast transition.

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Division of Nephrology, St Michael's Hospital, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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July 2011

Mouse models to study kidney development, function and disease.

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The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.

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July 2011

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June 2011

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Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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May 2011

The Sweet Pee model for Sglt2 mutation.

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The Samuel Lunenfeld Research Institute, TCP Building, Room 5-1015-2, 25 Orde Street, Toronto, Ontario M5T 3H7, Canada.

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The Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada.

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November 2010

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The Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada.

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October 2010

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Academic Renal Unit, School of Clinical Sciences, University of Bristol, Bristol BS8 1TH, UK; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario M5G 1X5, Canada. Electronic address:

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October 2010

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July 2010

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Department of Molecular and Cellular Biology, University of Guelph, 50 Stone Road East, New Science Complex, Guelph, Ontario, Canada.

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July 2009

Genetic susceptibility to HIV-associated nephropathy.

Authors:
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Samuel Lunenfeld Research Institute, 881-600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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August 2008

Ectopic notch activation in developing podocytes causes glomerulosclerosis.

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Program in Developmental Biology, Research Institute, and Division of Nephrology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 1084-600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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February 2008

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Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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January 2008

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The Samuel Lunenfeld Research Institute, University of Toronto, Toronto, ON, Canada.

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July 2007

Sizing up sialic acid in glomerular disease.

Authors:
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The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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June 2007

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December 2006

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Nat Med 2006 Sep 13;12(9):1081-7. Epub 2006 Aug 13.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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September 2006

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes.

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Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1038/nature04662DOI Listing
April 2006

Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival.

J Am Soc Nephrol 2006 Mar 25;17(3):724-35. Epub 2006 Jan 25.

Department of Maternal & Fetal Health, The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Room 855Q, 600 University of Toronto, Ontario, Canada M5G 1X5.

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http://dx.doi.org/10.1681/ASN.2005080810DOI Listing
March 2006

Rapid isolation of glomeruli coupled with gene expression profiling identifies downstream targets in Pod1 knockout mice.

J Am Soc Nephrol 2005 Nov 5;16(11):3247-55. Epub 2005 Oct 5.

The Samuel Lunenfeld Research Institute, University of Toronto, Toronto, Ontario, Canada.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2005030278
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http://dx.doi.org/10.1681/ASN.2005030278DOI Listing
November 2005

Conditional gene targeting in the kidney.

Curr Mol Med 2005 Aug;5(5):527-36

The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, ON, Canada.

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http://dx.doi.org/10.2174/1566524054553522DOI Listing
August 2005

Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction.

Nucleic Acids Res 2005 Mar 22;33(5):e51. Epub 2005 Mar 22.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital 600 University Avenue, Toronto, Ontario, Canada M5G 1X5.

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http://dx.doi.org/10.1093/nar/gni051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069131PMC
March 2005

WT1 activates a glomerular-specific enhancer identified from the human nephrin gene.

J Am Soc Nephrol 2004 Nov;15(11):2851-6

Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/01.ASN.0000143474.91362.C4DOI Listing
November 2004

Deciphering the renal code: advances in conditional gene targeting.

Physiology (Bethesda) 2004 Oct;19:245-52

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto M5G 1X5, Canada.

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http://dx.doi.org/10.1152/physiol.00009.2004DOI Listing
October 2004

Expression of Hairy/Enhancer of Split genes, Hes1 and Hes5, during murine nephron morphogenesis.

Gene Expr Patterns 2004 Oct;4(6):707-11

Program in Developmental Biology, Research Institute, The Hospital for Sick Children, 555 University Ave., Toronto, Ont., Canada M5G 1X8.

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http://dx.doi.org/10.1016/j.modgep.2004.04.007DOI Listing
October 2004

Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.

Development 2004 Aug;131(16):4095-105

Department of Maternal and Fetal Health, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Ontario M5G 1X5, Canada.

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http://dx.doi.org/10.1242/dev.01266DOI Listing
August 2004

A podocentric view of nephrology.

Curr Opin Nephrol Hypertens 2004 May;13(3):299-305

The Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/00041552-200405000-00006DOI Listing
May 2004

The role of VEGF-A in glomerular development and function.

Curr Opin Nephrol Hypertens 2004 Jan;13(1):9-15

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/00041552-200401000-00002DOI Listing
January 2004