Suresh S Ramalingam

Suresh S Ramalingam

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Suresh S Ramalingam

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Inhibition of mTOR complex 1/p70 S6 kinase signaling elevates PD-L1 levels in human cancer cells through enhancing protein stabilization accompanied with enhanced β-TrCP degradation.

Oncogene 2019 Aug 17;38(35):6270-6282. Epub 2019 Jul 17.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/s41388-019-0877-4DOI Listing
August 2019

Clinical prognostic model for older patients with advanced non-small cell lung cancer.

J Geriatr Oncol 2019 Jul 21;10(4):555-559. Epub 2019 Feb 21.

Duke University Medical Center, Durham, NC, USA; Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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https://linkinghub.elsevier.com/retrieve/pii/S18794068183019
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http://dx.doi.org/10.1016/j.jgo.2019.02.007DOI Listing
July 2019

Acetylation regulates ribonucleotide reductase activity and cancer cell growth.

Nat Commun 2019 Jul 19;10(1):3213. Epub 2019 Jul 19.

Departments of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, 1365C Clifton Road NE, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1038/s41467-019-11214-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642173PMC
July 2019

The Third-Generation EGFR Inhibitor, Osimertinib, Promotes c-FLIP Degradation, Enhancing Apoptosis Including TRAIL-Induced Apoptosis in NSCLC Cells with Activating EGFR Mutations.

Transl Oncol 2019 May 9;12(5):705-713. Epub 2019 Mar 9.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411612PMC
May 2019

Pharmacokinetic Study of Osimertinib in Cancer Patients with Mild or Moderate Hepatic Impairment.

J Pharmacol Exp Ther 2019 May 14;369(2):291-299. Epub 2019 Mar 14.

Medical Oncology Department, Ramón y Cajal Hospital, Madrid, Spain (E.G.); Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia (R.D.H., S.S.R.); Medical Oncology, Faculté de Médecine Lyon-Sud, Université Claude Bernard Lyon-1, Institute de Cancérologie des Hospices Civils de Lyon, Lyon, France (B.Y.); Medical Oncology Department, La Paz University Hospital, Autonoma University of Madrid (affiliated with CIBERONC-Instituto de Salud Carlos III), Madrid, Spain (J.F.B.); IQVIA, Kansas City, Missouri (H.G.); Institute for Drug Development, Mays Cancer Center at University of Texas, Health San Antonio, San Antonio, Texas (J.S.); Global Medicines Development, AstraZeneca, Cambridge, United Kingdom (H.M., K.S.); and Quantitative Clinical Pharmacology, Early Clinical Development IMED Biotech Unit, AstraZeneca, Cambridge, United Kingdom (M.J., K.V.)

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http://dx.doi.org/10.1124/jpet.118.255919DOI Listing
May 2019

Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.

Mol Cancer 2019 04 10;18(1):85. Epub 2019 Apr 10.

Division of Cancer Biology, Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1186/s12943-019-1012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456974PMC
April 2019

Role of osimertinib in the treatment of EGFR-mutation positive non-small-cell lung cancer.

Future Oncol 2019 Mar 18;15(8):805-816. Epub 2019 Jan 18.

Department of Hematology & Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.

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https://www.futuremedicine.com/doi/10.2217/fon-2018-0626
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http://dx.doi.org/10.2217/fon-2018-0626DOI Listing
March 2019

A new standard of care for patients with surgically unresectable stage III non-small cell lung cancer.

Cancer 2019 Mar 2. Epub 2019 Mar 2.

Department of Hematology and Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.31996DOI Listing
March 2019

Repurposing Food and Drug Administration-Approved Drugs to Promote Antitumor Immunity.

Cancer J 2019 Mar/Apr;25(2):88-99

Center for Affordable Medical Innovation and Department of Medicine, Emory University School of Medicine, Atlanta, GA.

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http://Insights.ovid.com/crossref?an=00130404-201903000-0000
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http://dx.doi.org/10.1097/PPO.0000000000000368DOI Listing
March 2019

Toxicity Related to Radiotherapy Dose and Targeting Strategy: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Locally Advanced Non-Small Cell Lung Cancer.

J Thorac Oncol 2019 Feb 4;14(2):298-303. Epub 2018 Oct 4.

Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina; Alliance Statistics and Data Center, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.jtho.2018.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348032PMC
February 2019

A banner year for immunotherapy and targeted therapy.

Nat Rev Clin Oncol 2019 02;16(2):79-80

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/s41571-018-0138-4DOI Listing
February 2019

Radiation Therapy Is Associated With an Increased Incidence of Cardiac Events in Patients with Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2018 10 6;102(2):383-390. Epub 2018 Jun 6.

Department of Radiation Oncology and Winship Cancer Institute at Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.ijrobp.2018.05.066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242711PMC
October 2018

Exploring Radiotherapy Targeting Strategy and Dose: A Pooled Analysis of Cooperative Group Trials of Combined Modality Therapy for Stage III NSCLC.

J Thorac Oncol 2018 08 22;13(8):1171-1182. Epub 2018 Apr 22.

Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina; Alliance Statistics and Data Center, Durham, North Carolina.

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http://dx.doi.org/10.1016/j.jtho.2018.04.011DOI Listing
August 2018

CNS Response to Osimertinib Versus Standard Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 Aug 28:JCO2018783118. Epub 2018 Aug 28.

Thanyanan Reungwetwattana, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; Kazuhiko Nakagawa, Kindai University School of Medicine, Osaka; Naoyuki Nogami, National Hospital Organization Shikoku Cancer Center, Matsuyama; Isamu Okamoto, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Byoung Chul Cho, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul; Eun Kyung Cho, Gachon University Gil Medical Center, Incheon; Ki Hyeong Lee, Chungbuk National University Hospital, Cheong-ju, Republic of Korea; Manuel Cobo, Institute of Biomedical Research in Málaga, Málaga University Hospital Regional, Málaga, Spain; Alessandro Bertolini, Hospital of Sondrio, Sondrio, Italy; Sabine Bohnet, Universitätsklinik Schleswig-Holstein, Lübeck, Germany; Caicun Zhou, Pulmonary Hospital of Tongji University, Shanghai, People's Republic of China; Natasha Leighl, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Rachel Hodge, Astrid McKeown, Andrew P. Brown, and Yuri Rukazenkov, AstraZeneca, Cambridge, United Kingdom; Suresh S. Ramalingam, Winship Cancer Institute, Emory University, Atlanta, GA; and Johan Vansteenkiste, University Hospital, Katholieke Universiteit Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1200/JCO.2018.78.3118DOI Listing
August 2018

Nivolumab plus Ipilimumab in Lung Cancer with a High Tumor Mutational Burden.

N Engl J Med 2018 May 16;378(22):2093-2104. Epub 2018 Apr 16.

From Memorial Sloan Kettering Cancer Center Hospital, New York (M.D.H.); Prof. Dr. Ion Chiricuta Institute of Oncology and Universitatea de Medicina si Farmacie Iuliu Hatieganu, Cluj-Napoca, Romania (T.-E.C.); Centrum Onkologii-Instytut im. Marii Sklodowskiej-Curie, Warsaw, Poland (A.P.); Seoul National University Bundang Hospital, Seoul, South Korea (J.S.L.); Ohio State University, Columbus (G.A.O.); Hôpital Sainte Musse, Toulon, France (C.A.-V.); Ospedale Santa Maria della Misericordia, Perugia, Italy (E.M.); First Department of Oncology, Metropolitan Hospital, Athens, Greece (H.L.); Antoni van Leeuwenhoek Ziekenhuis, Amsterdam (S.B.); Fundación Arturo López Pérez, Santiago, Chile (P.S.); Fox Chase Cancer Center, Philadelphia (H.B.); Winship Cancer Institute, Emory University, Atlanta (S.S.R.); Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.B.); LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany (M.R.); Princess Alexandra Hospital, Brisbane, QLD, Australia (K.J.O.); Bristol-Myers Squibb, Princeton, NJ (W.J.G., G.G., H.C., J.S., P.B., D.H., Y.F., F.N.); and Hospital Universitario 12 de Octubre, Centro Nacional de Investigaciones Oncológicas, Universidad Complutense, and CiberOnc, Madrid (L.P.-A.).

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http://dx.doi.org/10.1056/NEJMoa1801946DOI Listing
May 2018

Impact of a Non-small Cell Lung Cancer Educational Program for Interdisciplinary Teams.

Chest 2018 04 12;153(4):876-887. Epub 2017 Dec 12.

Department of Medicine, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2017.11.032DOI Listing
April 2018

Throwing More Cold Water on Heat Shock Protein 90 Inhibitors in NSCLC.

J Thorac Oncol 2018 04;13(4):473-474

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2018.02.010DOI Listing
April 2018

Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2018 03 25;36(9):841-849. Epub 2017 Aug 25.

Suresh S. Ramalingam, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA; James C.-H. Yang, National Taiwan University and National Taiwan University Cancer Center, Taipei, Taiwan; Chee Khoon Lee, St George Hospital, Sydney, New South Wales; Thomas John, Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Victoria, Australia; Takayasu Kurata, Kansai Medical University Hirakata Hospital, Osaka; Naoyuki Nogami, National Hospital Organization Shikoku Cancer Center, Matsuyama; Yuichiro Ohe, National Cancer Center Hospital East, Kashiwa-City, Japan; Dong-Wan Kim, Seoul National University Hospital, Seoul, Republic of Korea; Helen Mann, AstraZeneca, Macclesfield; Yuri Rukazenkov and Serban Ghiorghiu, AstraZeneca, Cambridge, United Kingdom; Daniel Stetson, Aleksandra Markovets, J. Carl Barrett, and Kenneth S. Thress, AstraZeneca, Waltham; and Pasi A. Jänne, Dana-Farber Cancer Institute and the Belfer Center for Applied Cancer Science, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.7576
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http://dx.doi.org/10.1200/JCO.2017.74.7576DOI Listing
March 2018

Tumor Mutation Burden: Leading Immunotherapy to the Era of Precision Medicine?

J Clin Oncol 2018 03 16;36(7):631-632. Epub 2018 Jan 16.

Conor E. Steuer and Suresh S. Ramalingam, Winship Cancer Institute of Emory University, Atlanta, GA.

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http://dx.doi.org/10.1200/JCO.2017.76.8770DOI Listing
March 2018

Molecular Testing Guideline for the Selection of Patients With Lung Cancer for Treatment With Targeted Tyrosine Kinase Inhibitors: American Society of Clinical Oncology Endorsement of the College of American Pathologists/International Association for the Study of Lung Cancer/Association for Molecular Pathology Clinical Practice Guideline Update.

J Clin Oncol 2018 03 5;36(9):911-919. Epub 2018 Feb 5.

Gregory P. Kalemkerian and Madelyn Lew, University of Michigan, Ann Arbor; James Pantelas, Greater Detroit Area; Michael Simoff, Henry Ford Hospital, Detroit, MI; Navneet Narula, Weill Cornell Medical College; Jessica Donington, New York University School of Medicine: Anjali Saqi, Columbia University Medical Center, New York, NY; Erin B. Kennedy, American Society of Clinical Oncology, Alexandria, VA; William A. Biermann, Chestnut Hill Hospital and Mercy Suburban Hospital, East Norriton; Baskaran Sundaram, Thomas Jefferson Medical School, Philadelphia, PA; Natasha B. Leighl, Princess Margaret Cancer Centre, Toronto, ON, Canada; Suresh S. Ramalingam, Winship Cancer Institute of Emory University, Atlanta, GA; Martin Reck, Lung Clinic Grosshansdorf, Grosshansdorf, Germany; and Navneet Singh, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://ascopubs.org/doi/10.1200/JCO.2017.76.7293
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http://dx.doi.org/10.1200/JCO.2017.76.7293DOI Listing
March 2018

Osimertinib in EGFR Mutation-Positive Advanced NSCLC.

N Engl J Med 2018 03;378(13):1262-1263

Emory University School of Medicine, Atlanta, GA

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http://dx.doi.org/10.1056/NEJMc1801669DOI Listing
March 2018

Immunotherapy in previously treated non-small cell lung cancer (NSCLC).

J Thorac Dis 2018 Feb;10(Suppl 3):S422-S432

Department of Hematology & Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.21037/jtd.2018.01.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861264PMC
February 2018

Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer.

N Engl J Med 2018 01 18;378(2):113-125. Epub 2017 Nov 18.

From Gustave Roussy Cancer Campus and University Paris-Sud, Orsay, France (J.-C.S., D.P.); the Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo (Y.O.), the Department of Thoracic Oncology, Osaka International Cancer Institute (F.I.), and the Department of Thoracic Oncology, Kansai Medical University Hospital (T.K.), Osaka, the Department of Thoracic Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama (N.N.), and the Research Institute for Diseases of the Chest, Graduate School of Medical Science, Kyushu University, Fukuoka (I.O.) - all in Japan; the Respiratory Oncology Unit, University Hospital KU Leuven, Leuven, Belgium (J.V.); Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok (T.R.), the Oncology Unit, Department of Medicine, Chiang Mai University, Chiang Mai (B.C.), and the Division of Medical Oncology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai (A.D.) - all in Thailand; the Division of Medical Oncology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-ju (K.H.L.), the Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (B.C.C.), and the Division of Hematology and Oncology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon (E.K.C.) - all in South Korea; Pulmonary Hospital of Tongji University, Shanghai (C.Z.), and Jilin Provincial Cancer Hospital, Changchun (Y.C.) - both in China; Hospital Umum Sarawak, Kuching, Malaysia (P.J.V.); National Cheng Kung University, Tainan, Taiwan (W.-C.S.); the Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (J.E.G.); the Department of Oncology, University College London Hospitals Biomedical Research Centre, and the Cancer Research UK Lung Cancer Centre of Excellence, London (S.-M.L.), and AstraZeneca, Cambridge (R.H., M.M., Y.R.) - all in the United Kingdom; and Emory University School of Medicine, Winship Cancer Institute, Atlanta (S.S.R.).

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http://dx.doi.org/10.1056/NEJMoa1713137DOI Listing
January 2018

Immune checkpoint inhibitors in advanced non-small cell lung cancer.

Cancer 2018 01 6;124(2):248-261. Epub 2017 Dec 6.

Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.31105DOI Listing
January 2018

Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy.

J Clin Invest 2018 01 11;128(1):500-516. Epub 2017 Dec 11.

Department of Radiation Oncology, Emory University School of Medicine and Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.

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http://dx.doi.org/10.1172/JCI92742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749500PMC
January 2018

CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions.

Annu Rev Med 2018 01;69:301-318

Emory Vaccine Center and Department of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia 30322, USA; email: , , , ,

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http://dx.doi.org/10.1146/annurev-med-012017-043208DOI Listing
January 2018

Access to Cancer Specialist Care and Treatment in Patients With Advanced Stage Lung Cancer.

Clin Lung Cancer 2017 11 26;18(6):640-650.e2. Epub 2017 Apr 26.

Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.cllc.2017.04.010DOI Listing
November 2017

HER2 mutations in lung adenocarcinomas: A report from the Lung Cancer Mutation Consortium.

Cancer 2017 Nov 25;123(21):4099-4105. Epub 2017 Jul 25.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/cncr.30869DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650517PMC
November 2017

Assays for PD-L1 Expression: Do All Roads Lead to Rome?

JAMA Oncol 2017 08;3(8):1058-1059

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1001/jamaoncol.2017.0012DOI Listing
August 2017

Pulmonary Sarcomatoid Carcinoma: An Analysis of the National Cancer Data Base.

Clin Lung Cancer 2017 05 7;18(3):286-292. Epub 2016 Dec 7.

Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.11.016DOI Listing
May 2017

Using Metaphors to Explain Molecular Testing to Cancer Patients.

Oncologist 2017 04 20;22(4):445-449. Epub 2017 Feb 20.

Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia, USA

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http://dx.doi.org/10.1634/theoncologist.2016-0270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388373PMC
April 2017

Osimertinib in Pretreated T790M-Positive Advanced Non-Small-Cell Lung Cancer: AURA Study Phase II Extension Component.

J Clin Oncol 2017 Apr 21;35(12):1288-1296. Epub 2017 Feb 21.

James Chih-Hsin Yang and Chia-Chi Lin, National Taiwan University Hospital, Taipei; Wu-Chou Su, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China; Myung-Ju Ahn, Sungkyunkwan University; Dong-Wan Kim, Seoul National University Hospital; Sang-We Kim, Asan Medical Center, Seoul; Joo-Hang Kim, CHA University, Gyeonggi-do, Republic of Korea; Suresh S. Ramalingam, Emory University School of Medicine, Atlanta, GA; Lecia V. Sequist, Massachusetts General Hospital; Pasi A. Jänne, Dana-Farber Cancer Institute, Boston, MA; David Planchard, Institut Gustave Roussy, Villejuif, France; Enriqueta Felip, Vall d'Hebron University Hospital, Barcelona, Spain; Fiona Blackhall, The Christie Hospital; University of Manchester, Manchester; Helen Mann and Serban Ghiorghiu, AstraZeneca, Cambridge; Mireille Cantarini, AstraZeneca, Macclesfield, United Kingdom; Daniel Haggstrom, Carolinas Healthcare System, Charlotte, NC; Kiyotaka Yoh, National Cancer Center Hospital East, Kashiwa, Chiba; Tomonori Hirashima, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases, Osaka, Japan; Silvia Novello, University of Turin, Turin, Italy; and Kathryn Gold, University of California San Diego Moores Cancer Center, San Diego, CA.

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http://ascopubs.org/doi/10.1200/JCO.2016.70.3223
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http://dx.doi.org/10.1200/JCO.2016.70.3223DOI Listing
April 2017

Epidermal Growth Factor Receptor Mutated Advanced Non-Small Cell Lung Cancer: A Changing Treatment Paradigm.

Hematol Oncol Clin North Am 2017 02;31(1):83-99

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Clifton Rd, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.hoc.2016.08.003DOI Listing
February 2017

Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.

N Engl J Med 2017 02 6;376(7):629-640. Epub 2016 Dec 6.

From the State Key Laboratory in Oncology in South China, Sir Y.K. Pao Centre for Cancer, Department of Clinical Oncology, Chinese University of Hong Kong, Hong Kong (T.S.M.), the Division of Pulmonary Oncology, Guangdong Lung Cancer Institute, Guangdong General Hospital, and Guangdong Academy of Medical Sciences, Guangzhou (Y.-L.W.), and the Department of Respiratory Disease, Daping Hospital, Third Military Medical University, Chongqing (Y.H.) - all in China; the Department of Medicine, Division of Hematology-Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine, (M.-J.A.), and the Yonsei Cancer Center, Department of Internal Medicine, Division of Medical Oncology, Yonsei University College of Medicine (H.R.K.), Seoul, South Korea; the Thoracic Oncology Unit, Medical Oncology Department, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan (M.C.G.); the Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta (S.S.R.); the Department of Medical Oncology and Haematology, Princess Margaret Cancer Centre, Toronto (F.A.S.); the Third Department of Internal Medicine, Wakayama Medical University, Wakayama, Japan (H.A.); the Department of Thoracic Oncology, the Netherlands Cancer Institute, Plesmanlaan, Amsterdam (W.S.M.E.T.); the Clinical Research Unit, Division of Cancer Services, St. George Hospital, Kogarah, NSW, Australia (C.K.L.); the Department of Hematology-Oncology, Johann Wolfgang Goethe University Medical Center, Frankfurt am Main, Germany (M.S.); AstraZeneca, Cambridge, United Kingdom (A.T., H.M., M.M., S.G.); and the Department of Thoracic-Head and Neck Medical Oncology, University of Texas M.D. Anderson Cancer Center, Houston (V.A.P.).

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http://dx.doi.org/10.1056/NEJMoa1612674DOI Listing
February 2017

Overview of Thoracic Oncology Trials in Cooperative Groups Around the Globe.

Clin Lung Cancer 2017 01 27;18(1):5-12. Epub 2016 Jun 27.

Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361177PMC
January 2017

Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report.

Cancer Immunol Immunother 2017 01 22;66(1):45-50. Epub 2016 Oct 22.

Department of Hematology and Medical Oncology, Emory University School of Medicine, 1365-C Clifton Road, NE, Suite C3080, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1007/s00262-016-1918-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588660PMC
January 2017

National Cancer Database Analysis of Proton Versus Photon Radiation Therapy in Non-Small Cell Lung Cancer.

Int J Radiat Oncol Biol Phys 2017 01 11;97(1):128-137. Epub 2016 Oct 11.

Winship Cancer Institute, Emory University, Atlanta, Georgia; Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.ijrobp.2016.10.001DOI Listing
January 2017

American Society of Clinical Oncology Policy Brief: FDA's Regulation of Electronic Nicotine Delivery Systems and Tobacco Products.

J Oncol Pract 2017 01 23;13(1):58-60. Epub 2016 Oct 23.

American Society of Clinical Oncology, Alexandria, VA; Medical University of South Carolina, Charleston, SC; McMaster University Juravinski Cancer Centre, Hamilton, Ontario, Canada; Emory University, Winship Cancer Institute, Atlanta, GA; and Moffit Cancer Center, Tampa, FL.

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http://dx.doi.org/10.1200/JOP.2016.018200DOI Listing
January 2017

Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012.

J Clin Oncol 2016 11 30;34(33):3992-3999. Epub 2016 Sep 30.

Herbert H. Pang and Perry Cheng, School of Public Health, Li Ka Shing Faculty of Medicine, Hong Kong, Special Administrative Region, People's Republic of China; Herbert H. Pang, Xiaofei Wang, Ying Zhang, Thomas E. Stinchcombe, and Harvey J. Cohen, Duke University School of Medicine, Durham, NC; Melisa L. Wong, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco; David Gandara, University of California, Davis Comprehensive Cancer Center, Sacramento, CA; Apar Kishor Ganti, Veterans Affairs Nebraska Western Iowa Health Care System and University of Nebraska Medical Center, Omaha, NE; Daniel J. Sargent and Sumithra J. Mandrekar, Mayo Clinic, Rochester, MN; Chen Hu, NRG Oncology Statistics and Data Management Center, Philadelphia, PA; Chen Hu, Johns Hopkins University School of Medicine, Baltimore, MD; Mary W. Redman, Fred Hutchinson Cancer Research Center, Seattle, WA; Judith B. Manola, Dana-Farber Cancer Institute, Boston, MA; Richard L. Schilsky, ASCO, Alexandria, VA; Jeffrey D. Bradley, Washington University School of Medicine, St Louis, MO; Alex A. Adjei, Roswell Park Cancer Institute, Buffalo, NY; Suresh S. Ramalingam, The Winship Cancer Institute of Emory University, Atlanta, GA; and Everett E. Vokes, University of Chicago, Chicago, IL.

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http://dx.doi.org/10.1200/JCO.2016.67.7088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477832PMC
November 2016

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.

Cancer Lett 2016 10 19;380(2):494-504. Epub 2016 Jul 19.

Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. Electronic address:

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http://search.proquest.com/openview/96fc37bbd6ea5af450a03f13
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http://dx.doi.org/10.1016/j.canlet.2016.07.021DOI Listing
October 2016

Metastatic Lung Cancer: Emerging Therapeutic Strategies.

Semin Respir Crit Care Med 2016 10 12;37(5):736-749. Epub 2016 Oct 12.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1055/s-0036-1592111DOI Listing
October 2016

Lung Adenocarcinoma Staging Using the 2011 IASLC/ATS/ERS Classification: A Pooled Analysis of Adenocarcinoma In Situ and Minimally Invasive Adenocarcinoma.

Clin Lung Cancer 2016 09 30;17(5):e57-e64. Epub 2016 Mar 30.

Department of Pathology and Laboratory Medicine, Winship Cancer Institute of Emory University, Atlanta, GA. Electronic address:

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http://dx.doi.org/10.1016/j.cllc.2016.03.009DOI Listing
September 2016

EGFR Fusions as Novel Therapeutic Targets in Lung Cancer.

Cancer Discov 2016 06 21;6(6):601-11. Epub 2016 Apr 21.

Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee. Addario Lung Cancer Medical Institute, Cambridge, Massachusetts. Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee. Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893907PMC
June 2016