Publications by authors named "Sungwhan F Oh"

20Publications

PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function.

Authors:
Sreekanth Rajan Yongwoo Jang Chun-Hyung Kim Woori Kim Hui Ting Toh Jeha Jeon Bin Song Aida Serra Julien Lescar Jun Yeob Yoo Serap Beldar Hong Ye Congbao Kang Xue-Wei Liu Melissa Feitosa Yeahan Kim Dabin Hwang Geraldine Goh Kah-Leong Lim Hye Min Park Choong Hwan Lee Sungwhan F Oh Gregory A Petsko Ho Sup Yoon Kwang-Soo Kim

Nat Chem Biol 2020 08 25;16(8):876-886. Epub 2020 May 25.

Molecular Neurobiology Laboratory, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA.

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August 2020

Microbial bile acid metabolites modulate gut RORγ regulatory T cell homeostasis.

Authors:
Xinyang Song Ximei Sun Sungwhan F Oh Meng Wu Yanbo Zhang Wen Zheng Naama Geva-Zatorsky Ray Jupp Diane Mathis Christophe Benoist Dennis L Kasper

Nature 2020 01 25;577(7790):410-415. Epub 2019 Dec 25.

Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.

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January 2020

Symbionts exploit complex signaling to educate the immune system.

Authors:
Deniz Erturk-Hasdemir Sungwhan F Oh Nihal A Okan Giuseppe Stefanetti Francesca S Gazzaniga Peter H Seeberger Scott E Plevy Dennis L Kasper

Proc Natl Acad Sci U S A 2019 Dec 6. Epub 2019 Dec 6.

Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115;

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December 2019

Dietary and Microbial Oxazoles Induce Intestinal Inflammation by Modulating Aryl Hydrocarbon Receptor Responses.

Authors:
Shankar S Iyer Thomas Gensollen Amit Gandhi Sungwhan F Oh Joana F Neves Frederic Collin Richard Lavin Carme Serra Jonathan Glickman Punyanganie S A de Silva R Balfour Sartor Gurdyal Besra Russell Hauser Anthony Maxwell Amadeu Llebaria Richard S Blumberg

Cell 2018 05;173(5):1123-1134.e11

Division of Gastroenterology, Hepatology, and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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May 2018

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.

Authors:
Cholsoon Jang Sungwhan F Oh Shogo Wada Glenn C Rowe Laura Liu Mun Chun Chan James Rhee Atsushi Hoshino Boa Kim Ayon Ibrahim Luisa G Baca Esl Kim Chandra C Ghosh Samir M Parikh Aihua Jiang Qingwei Chu Daniel E Forman Stewart H Lecker Saikumari Krishnaiah Joshua D Rabinowitz Aalim M Weljie Joseph A Baur Dennis L Kasper Zoltan Arany

Nat Med 2016 Apr 7;22(4):421-6. Epub 2016 Mar 7.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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April 2016

Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells.

Authors:
Dingding An Sungwhan F Oh Torsten Olszak Joana F Neves Fikri Y Avci Deniz Erturk-Hasdemir Xi Lu Sebastian Zeissig Richard S Blumberg Dennis L Kasper

Cell 2014 Jan;156(1-2):123-33

Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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January 2014

Resolvin D1 and aspirin-triggered resolvin D1 promote resolution of allergic airways responses.

Authors:
Alexandre P Rogerio Oliver Haworth Roxanne Croze Sungwhan F Oh Mohib Uddin Troy Carlo Michael A Pfeffer Rebekah Priluck Charles N Serhan Bruce D Levy

J Immunol 2012 Aug 16;189(4):1983-91. Epub 2012 Jul 16.

Pulmonary and Critical Care Medicine Division, Department of Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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August 2012

Infection regulates pro-resolving mediators that lower antibiotic requirements.

Authors:
Nan Chiang Gabrielle Fredman Fredrik Bäckhed Sungwhan F Oh Thad Vickery Birgitta A Schmidt Charles N Serhan

Nature 2012 Apr 25;484(7395):524-8. Epub 2012 Apr 25.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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April 2012

Resolvin E2 formation and impact in inflammation resolution.

Authors:
Sungwhan F Oh Maria Dona Gabrielle Fredman Sriram Krishnamoorthy Daniel Irimia Charles N Serhan

J Immunol 2012 May 26;188(9):4527-34. Epub 2012 Mar 26.

Department of Anesthesiology, Perioperative and Pain Medicine, Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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May 2012

Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections.

Authors:
David M Tobin Francisco J Roca Sungwhan F Oh Ross McFarland Thad W Vickery John P Ray Dennis C Ko Yuxia Zou Nguyen D Bang Tran T H Chau Jay C Vary Thomas R Hawn Sarah J Dunstan Jeremy J Farrar Guy E Thwaites Mary-Claire King Charles N Serhan Lalita Ramakrishnan

Cell 2012 Feb;148(3):434-46

Department of Microbiology, University of Washington, Seattle, WA 98195, USA.

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February 2012

Metabolomics-lipidomics of eicosanoids and docosanoids generated by phagocytes.

Authors:
Rong Yang Nan Chiang Sungwhan F Oh Charles N Serhan

Curr Protoc Immunol 2011 Nov;Chapter 14:Unit 14.26

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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November 2011

Impaired phagocytosis in localized aggressive periodontitis: rescue by Resolvin E1.

Authors:
Gabrielle Fredman Sungwhan F Oh Srinivas Ayilavarapu Hatice Hasturk Charles N Serhan Thomas E Van Dyke

PLoS One 2011 14;6(9):e24422. Epub 2011 Sep 14.

Department of Periodontology, The Forsyth Institute, Cambridge, Massachusetts, United States of America.

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February 2012

Chiral lipidomics of E-series resolvins: aspirin and the biosynthesis of novel mediators.

Authors:
Sungwhan F Oh Thad W Vickery Charles N Serhan

Biochim Biophys Acta 2011 Nov 16;1811(11):737-47. Epub 2011 Jun 16.

Department of Anesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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November 2011

Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation.

Authors:
Sungwhan F Oh Padmini S Pillai Antonio Recchiuti Rong Yang Charles N Serhan

J Clin Invest 2011 Feb 4;121(2):569-81. Epub 2011 Jan 4.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115-5727, USA.

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February 2011

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions.

Authors:
Charles N Serhan Rong Yang Kimberly Martinod Kie Kasuga Padmini S Pillai Timothy F Porter Sungwhan F Oh Matthew Spite

J Exp Med 2009 Jan 22;206(1):15-23. Epub 2008 Dec 22.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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January 2009

Resolvin E1 metabolome in local inactivation during inflammation-resolution.

Authors:
Song Hong Timothy F Porter Yan Lu Sungwhan F Oh Padmini S Pillai Charles N Serhan

J Immunol 2008 Mar;180(5):3512-9

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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March 2008

Resolvin D1 and its aspirin-triggered 17R epimer. Stereochemical assignments, anti-inflammatory properties, and enzymatic inactivation.

Authors:
Yee-Ping Sun Sungwhan F Oh Jasim Uddin Rong Yang Katherine Gotlinger Eric Campbell Sean P Colgan Nicos A Petasis Charles N Serhan

J Biol Chem 2007 Mar 23;282(13):9323-34. Epub 2007 Jan 23.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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March 2007

Resolvin E2: identification and anti-inflammatory actions: pivotal role of human 5-lipoxygenase in resolvin E series biosynthesis.

Authors:
Eric Tjonahen Sungwhan F Oh Jeffrey Siegelman Siva Elangovan Katherine B Percarpio Song Hong Makoto Arita Charles N Serhan

Chem Biol 2006 Nov;13(11):1193-202

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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November 2006

Divergent cyclooxygenase responses to fatty acid structure and peroxide level in fish and mammalian prostaglandin H synthases.

Authors:
Wen Liu Dazhe Cao Sungwhan F Oh Charles N Serhan Richard J Kulmacz

FASEB J 2006 Jun;20(8):1097-108

Department of Internal Medicine, University of Texas Health Science Center at Houston, 6431 Fannin St., Houston, Texas 77030, USA.

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June 2006

Metabolic inactivation of resolvin E1 and stabilization of its anti-inflammatory actions.

Authors:
Makoto Arita Sungwhan F Oh Tomomichi Chonan Song Hong Siva Elangovan Yee-Ping Sun Jasim Uddin Nicos A Petasis Charles N Serhan

J Biol Chem 2006 Aug 6;281(32):22847-54. Epub 2006 Jun 6.

Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard School of Dental Medicine, Harvard Medical School, Boston, Massachusetts 02115, USA.

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August 2006