Sumit Chanda

Sumit Chanda

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Sumit Chanda

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Sensor Sensibility-HIV-1 and the Innate Immune Response.

Cells 2020 Jan 20;9(1). Epub 2020 Jan 20.

Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.3390/cells9010254DOI Listing
January 2020

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate.

PLoS One 2019 4;14(2):e0211746. Epub 2019 Feb 4.

Department of Immunology & Microbiology, The Scripps Research Institute, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211746PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361451PMC
November 2019

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets.

Nat Commun 2019 04 3;10(1):1523. Epub 2019 Apr 3.

Immunity and Pathogenesis Program, Infectious and Inflammatory Disease Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.

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http://dx.doi.org/10.1038/s41467-019-09234-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447622PMC
April 2019

SNW1, a Novel Transcriptional Regulator of the NF-κB Pathway.

Mol Cell Biol 2019 02 16;39(3). Epub 2019 Jan 16.

Salk Institute for Biological Studies, La Jolla, California, USA

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http://dx.doi.org/10.1128/MCB.00415-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336138PMC
February 2019

HIV-1 Fusion with CD4+ T cells Is Promoted by Proteins Involved in Endocytosis and Intracellular Membrane Trafficking.

Viruses 2019 01 25;11(2). Epub 2019 Jan 25.

Department of Pediatric, Division of Infectious Diseases, Emory University School of Medicine, 2015 Uppergate Drive, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.3390/v11020100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409670PMC
January 2019

Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein.

ACS Infect Dis 2018 02 4;4(2):146-157. Epub 2018 Jan 4.

Department of Microbiology, Icahn School of Medicine at Mount Sinai , New York, New York 10029, United States.

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http://dx.doi.org/10.1021/acsinfecdis.7b00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145453PMC
February 2018

Large-Scale Arrayed Analysis of Protein Degradation Reveals Cellular Targets for HIV-1 Vpu.

Cell Rep 2018 02;22(9):2493-2503

Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916846PMC
February 2018

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity.

Cell 2017 05;169(4):679-692.e14

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6574, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.04.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217988PMC
May 2017

Inhibition of NUCKS Facilitates Corneal Recovery Following Alkali Burn.

Sci Rep 2017 01 20;7:41224. Epub 2017 Jan 20.

Department of Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1038/srep41224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247723PMC
January 2017

A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.

Cell Host Microbe 2016 Nov;20(5):642-653

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130111PMC
November 2016

Interferon but not MxB inhibits foamy retroviruses.

Virology 2016 Jan 21;488:51-60. Epub 2015 Nov 21.

Clinic for Gastroenterology, Hepatology, and Infectiology, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2015.10.034DOI Listing
January 2016

MxB Is Not Responsible for the Blocking of HIV-1 Infection Observed in Alpha Interferon-Treated Cells.

J Virol 2015 Dec 30;90(6):3056-64. Epub 2015 Dec 30.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA

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http://jvi.asm.org/lookup/doi/10.1128/JVI.03146-15
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http://dx.doi.org/10.1128/JVI.03146-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810631PMC
December 2015

An integrated map of HIV-human protein complexes that facilitate viral infection.

PLoS One 2014 9;9(5):e96687. Epub 2014 May 9.

Departments of Medicine and Bioengineering, University of California at San Diego, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0096687PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016004PMC
October 2015

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2.

Retrovirology 2015 Aug 22;12:74. Epub 2015 Aug 22.

Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, USA.

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http://dx.doi.org/10.1186/s12977-015-0200-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546280PMC
August 2015

Tumor suppressor cylindromatosis (CYLD) controls HIV transcription in an NF-κB-dependent manner.

J Virol 2014 Jul 23;88(13):7528-40. Epub 2014 Apr 23.

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA Division of Infectious Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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http://dx.doi.org/10.1128/JVI.00239-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4054419PMC
July 2014

RIOK3 is an adaptor protein required for IRF3-mediated antiviral type I interferon production.

J Virol 2014 Jul 7;88(14):7987-97. Epub 2014 May 7.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA

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http://dx.doi.org/10.1128/JVI.00643-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097797PMC
July 2014

A short hairpin RNA screen of interferon-stimulated genes identifies a novel negative regulator of the cellular antiviral response.

mBio 2013 Jun 18;4(3):e00385-13. Epub 2013 Jun 18.

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1128/mBio.00385-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684836PMC
June 2013

Identification of small molecules that interfere with H1N1 influenza A viral replication.

ChemMedChem 2012 Dec 8;7(12):2227-35. Epub 2012 Nov 8.

Infectious and Inflammatory Disease Center (IIDC) and Cancer Center (CC), Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1002/cmdc.201200453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769975PMC
December 2012

Functional genomic and high-content screening for target discovery and deconvolution.

Expert Opin Drug Discov 2012 Oct 4;7(10):955-68. Epub 2012 Aug 4.

Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.1517/17460441.2012.711311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954969PMC
October 2012

Fer kinase regulates cell migration through α-dystroglycan glycosylation.

Mol Biol Cell 2012 Mar 11;23(5):771-80. Epub 2012 Jan 11.

Glycobiology Unit, Tumor Microenvironment Program, Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.

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http://www.molbiolcell.org/doi/10.1091/mbc.e11-06-0517
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http://dx.doi.org/10.1091/mbc.E11-06-0517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290637PMC
March 2012

In silico gene prioritization by integrating multiple data sources.

PLoS One 2011 24;6(6):e21137. Epub 2011 Jun 24.

Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0021137PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123338PMC
November 2011

GPS-Prot: a web-based visualization platform for integrating host-pathogen interaction data.

BMC Bioinformatics 2011 Jul 22;12:298. Epub 2011 Jul 22.

Department of Cellular and Molecular Pharmacology, University of California San Francisco, 1700 4th Street, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1186/1471-2105-12-298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213248PMC
July 2011

Identifying HIV-1 host cell factors by genome-scale RNAi screening.

Methods 2011 Jan 21;53(1):3-12. Epub 2010 Jul 21.

Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.ymeth.2010.07.009DOI Listing
January 2011

A human MAP kinase interactome.

Nat Methods 2010 Oct;7(10):801-5

Departments of Medicine and Bioengineering, University of California at San Diego, La Jolla, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967489PMC
http://dx.doi.org/10.1038/nmeth.1506DOI Listing
October 2010

Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activator.

J Biol Chem 2010 Aug 1;285(33):25139-53. Epub 2010 Jun 1.

Department of Microbiology, Division of Hematology-Oncology, David Geffen School of Medicine, UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1074/jbc.M110.137737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919076PMC
August 2010

Determining the distribution of probes between different subcellular locations through automated unmixing of subcellular patterns.

Proc Natl Acad Sci U S A 2010 Feb 1;107(7):2944-9. Epub 2010 Feb 1.

Center for Bioimage Informatics and Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1073/pnas.0912090107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840343PMC
February 2010

Human Cep192 is required for mitotic centrosome and spindle assembly.

Curr Biol 2007 Nov 1;17(22):1960-6. Epub 2007 Nov 1.

Department of Physiology and Biophysics, Albert Einstein College of Medicine, New York, New York 10461, USA.

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http://dx.doi.org/10.1016/j.cub.2007.10.019DOI Listing
November 2007

A probability-based approach for the analysis of large-scale RNAi screens.

Nat Methods 2007 Oct 9;4(10):847-9. Epub 2007 Sep 9.

The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, California 92121, USA.

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http://dx.doi.org/10.1038/nmeth1089DOI Listing
October 2007

A role for IkappaB kinase 2 in bipolar spindle assembly.

Proc Natl Acad Sci U S A 2007 Oct 15;104(43):16940-5. Epub 2007 Oct 15.

Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1073/pnas.0706493104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040438PMC
October 2007

B cell terminal differentiation factor XBP-1 induces reactivation of Kaposi's sarcoma-associated herpesvirus.

FEBS Lett 2007 Jul 29;581(18):3485-8. Epub 2007 Jun 29.

Department of Molecular and Medical Pharmacology, University of California at Los Angeles, CHS23-120, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.febslet.2007.06.056DOI Listing
July 2007

High-content screening of functional genomic libraries.

Methods Enzymol 2006 ;414:530-65

Genomics Institute of the Novartis Research Foundation, San Diego, CA, USA.

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http://dx.doi.org/10.1016/S0076-6879(06)14028-8DOI Listing
December 2006

Isolation, characterization, and genetic complementation of a cellular mutant resistant to retroviral infection.

Proc Natl Acad Sci U S A 2006 Oct 16;103(43):15933-8. Epub 2006 Oct 16.

Department of Genetics, Cell Biology, and Development, University of Minnesota, 420 Delaware Street, SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1073/pnas.0602674103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636844PMC
October 2006

Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling.

Cell Metab 2006 May;3(5):367-78

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/j.cmet.2006.03.006DOI Listing
May 2006

A functional genomics approach to the mode of action of apratoxin A.

Nat Chem Biol 2006 Mar 12;2(3):158-67. Epub 2006 Feb 12.

Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1038/nchembio769DOI Listing
March 2006

Methods for the functional genomic analysis of ubiquitin ligases.

Methods Enzymol 2005 ;398:280-91

Department of Cell and Molecular Biology, Genomics Institute, Novartis Research Foundation (GNF), San Diego, CA 92121, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S007668790598023
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http://dx.doi.org/10.1016/S0076-6879(05)98023-3DOI Listing
December 2005

Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis.

Proc Natl Acad Sci U S A 2005 Feb 26;102(6):1927-32. Epub 2005 Jan 26.

Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0409472102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548559PMC
February 2005

The promise of genomics to identify novel therapeutic targets.

Expert Opin Ther Targets 2004 Dec;8(6):587-96

The Genomics Institute of the Novartis Research Foundation, 10675 John J. Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1517/14728222.8.6.587DOI Listing
December 2004

Identification of p53 regulators by genome-wide functional analysis.

Proc Natl Acad Sci U S A 2004 Mar 27;101(10):3456-61. Epub 2004 Feb 27.

Department of Chemistry, The Scripps Research Institute, Mail Stop SR202, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1073/pnas.0308562100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373483PMC
March 2004

Bmi-1 regulation of INK4A-ARF is a downstream requirement for transformation of hematopoietic progenitors by E2a-Pbx1.

Mol Cell 2003 Aug;12(2):393-400

Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1016/s1097-2765(03)00277-6DOI Listing
August 2003

Identification of homeodomain proteins, PBX1 and PREP1, involved in the transcription of murine leukemia virus.

Mol Cell Biol 2003 Feb;23(3):831-41

Genomics Institute of the Novartis Research Foundation, San Diego, California 92121, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC140703PMC
http://dx.doi.org/10.1128/mcb.23.3.831-841.2003DOI Listing
February 2003

Fulfilling the promise: drug discovery in the post-genomic era.

Drug Discov Today 2003 Feb;8(4):168-74

Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA.

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http://dx.doi.org/10.1016/s1359-6446(02)02595-3DOI Listing
February 2003