Publications by authors named "Sumio Sugano"

100Publications

Complete genome sequence and bioinformatics analysis of nine Egyptian females with clinical information from different geographic regions in Egypt.

Gene 2020 Oct 27:145237. Epub 2020 Oct 27.

Korean Genomics Center (KOGIC), UNIST, Republic of Korea; Department of Biomedical Engineering, School of Life Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.

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http://dx.doi.org/10.1016/j.gene.2020.145237DOI Listing
October 2020

Corrigendum: Networking and Specificity-Changing DNA Methyltransferases in .

Front Microbiol 2020 22;11:596598. Epub 2020 Sep 22.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3389/fmicb.2020.596598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537328PMC
September 2020

Spindle assembly checkpoint competence in aneuploid canine malignant melanoma cell lines.

Tissue Cell 2020 Dec 3;67:101403. Epub 2020 Jul 3.

Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.tice.2020.101403DOI Listing
December 2020

Networking and Specificity-Changing DNA Methyltransferases in .

Front Microbiol 2020 17;11:1628. Epub 2020 Jul 17.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.3389/fmicb.2020.01628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379913PMC
July 2020

Characterization of cancer omics and drug perturbations in panels of lung cancer cells.

Sci Rep 2019 12 20;9(1):19529. Epub 2019 Dec 20.

Division of Translational Informatics, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.

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http://dx.doi.org/10.1038/s41598-019-55692-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925249PMC
December 2019

DNA aneuploidy and centrosome amplification in canine tumor cell lines.

Tissue Cell 2019 Dec 19;61:67-71. Epub 2019 Sep 19.

Laboratory of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.tice.2019.09.003DOI Listing
December 2019

Monoallelic, antisense and total RNA transcription in an neural differentiation system based on F1 hybrid mice.

J Cell Sci 2019 09 9;132(17). Epub 2019 Sep 9.

Transdisciplinary Research Integration Center, Research Organization of Information and Systems, Tokyo 105-0001, Japan

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http://dx.doi.org/10.1242/jcs.228973DOI Listing
September 2019

Quantifying local malignant adaptation in tissue-specific evolutionary trajectories by harnessing cancer's repeatability at the genetic level.

Evol Appl 2019 Jun 18;12(5):1062-1075. Epub 2019 Mar 18.

Univ Lyon, Université Claude Bernard Lyon 1, INSERM 1052, CNRS 5286, Centre Léon Bérard Cancer Research Center of Lyon Lyon France.

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http://dx.doi.org/10.1111/eva.12781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503823PMC
June 2019

Evaluation and application of RNA-Seq by MinION.

DNA Res 2019 Feb;26(1):55-65

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/dnares/dsy038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379022PMC
February 2019

Effects of androgen and oestrogen on IGF pathways controlling phallus growth.

Reproduction 2019 01;157(1):1-12

School of BioSciences, The University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1530/REP-18-0416DOI Listing
January 2019

Hormone-responsive genes in the SHH and WNT/β-catenin signaling pathways influence urethral closure and phallus growth.

Biol Reprod 2018 10;99(4):806-816

School of BioSciences, The University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1093/biolre/ioy117DOI Listing
October 2018

Candidate gene identification of ovulation-inducing genes by RNA sequencing with an in vivo assay in zebrafish.

PLoS One 2018 1;13(5):e0196544. Epub 2018 May 1.

Integrated Bioscience Section, Graduate School of Science and Technology, National University Corporation Shizuoka University, Ohya 836, Suruga-ku, Shizuoka, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196544PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929532PMC
August 2018

No novel, high penetrant gene might remain to be found in Japanese patients with unknown MODY.

J Hum Genet 2018 Jul 18;63(7):821-829. Epub 2018 Apr 18.

Department of Diabetes and Endocrinology, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1038/s10038-018-0449-4DOI Listing
July 2018

Identification of potential regulatory mutations using multi-omics analysis and haplotyping of lung adenocarcinoma cell lines.

Sci Rep 2018 03 21;8(1):4926. Epub 2018 Mar 21.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan.

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http://dx.doi.org/10.1038/s41598-018-23342-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862974PMC
March 2018

Stimulation of alpha2-adrenergic receptors impairs influenza virus infection.

Sci Rep 2018 03 15;8(1):4631. Epub 2018 Mar 15.

Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.

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http://www.nature.com/articles/s41598-018-22927-0
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http://dx.doi.org/10.1038/s41598-018-22927-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854622PMC
March 2018

Combinatory use of distinct single-cell RNA-seq analytical platforms reveals the heterogeneous transcriptome response.

Sci Rep 2018 02 22;8(1):3482. Epub 2018 Feb 22.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, 277-8562, Japan.

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http://dx.doi.org/10.1038/s41598-018-21161-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823859PMC
February 2018

Transcriptome profiling reveals infection strategy of an insect maculavirus.

DNA Res 2018 Jan 17. Epub 2018 Jan 17.

Department of Agrobiology and Bioresources, School of Agriculture, Utsunomiya University, Utsunomiya-shi, Tochigi 321-8505, Japan.

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http://dx.doi.org/10.1093/dnares/dsx056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014269PMC
January 2018

Decreased KPNB1 Expression is Induced by PLK1 Inhibition and Leads to Apoptosis in Lung Adenocarcinoma.

J Cancer 2017 6;8(19):4125-4140. Epub 2017 Nov 6.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.7150/jca.21802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706017PMC
November 2017

Comprehensive analysis of gene expression profiles reveals novel candidates of chemotherapy resistant factors in canine lymphoma.

Vet J 2017 Oct 8;228:18-21. Epub 2017 Oct 8.

Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.

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http://dx.doi.org/10.1016/j.tvjl.2017.10.002DOI Listing
October 2017

DBTSS/DBKERO for integrated analysis of transcriptional regulation.

Nucleic Acids Res 2018 01;46(D1):D229-D238

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Chiba, Japan.

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http://dx.doi.org/10.1093/nar/gkx1001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753362PMC
January 2018

Sequencing and phasing cancer mutations in lung cancers using a long-read portable sequencer.

DNA Res 2017 Dec;24(6):585-596

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/dnares/dsx027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726485PMC
December 2017

Large-scale DNA Barcode Library Generation for Biomolecule Identification in High-throughput Screens.

Sci Rep 2017 10 24;7(1):13899. Epub 2017 Oct 24.

Laboratory of Functional Genomics, Department of Computational Biology and Medical Science, School of Frontier Sciences, University of Tokyo, Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/s41598-017-12825-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654825PMC
October 2017

Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome.

Authors:
John L Bowman Takayuki Kohchi Katsuyuki T Yamato Jerry Jenkins Shengqiang Shu Kimitsune Ishizaki Shohei Yamaoka Ryuichi Nishihama Yasukazu Nakamura Frédéric Berger Catherine Adam Shiori Sugamata Aki Felix Althoff Takashi Araki Mario A Arteaga-Vazquez Sureshkumar Balasubrmanian Kerrie Barry Diane Bauer Christian R Boehm Liam Briginshaw Juan Caballero-Perez Bruno Catarino Feng Chen Shota Chiyoda Mansi Chovatia Kevin M Davies Mihails Delmans Taku Demura Tom Dierschke Liam Dolan Ana E Dorantes-Acosta D Magnus Eklund Stevie N Florent Eduardo Flores-Sandoval Asao Fujiyama Hideya Fukuzawa Bence Galik Daniel Grimanelli Jane Grimwood Ueli Grossniklaus Takahiro Hamada Jim Haseloff Alexander J Hetherington Asuka Higo Yuki Hirakawa Hope N Hundley Yoko Ikeda Keisuke Inoue Shin-Ichiro Inoue Sakiko Ishida Qidong Jia Mitsuru Kakita Takehiko Kanazawa Yosuke Kawai Tomokazu Kawashima Megan Kennedy Keita Kinose Toshinori Kinoshita Yuji Kohara Eri Koide Kenji Komatsu Sarah Kopischke Minoru Kubo Junko Kyozuka Ulf Lagercrantz Shih-Shun Lin Erika Lindquist Anna M Lipzen Chia-Wei Lu Efraín De Luna Robert A Martienssen Naoki Minamino Masaharu Mizutani Miya Mizutani Nobuyoshi Mochizuki Isabel Monte Rebecca Mosher Hideki Nagasaki Hirofumi Nakagami Satoshi Naramoto Kazuhiko Nishitani Misato Ohtani Takashi Okamoto Masaki Okumura Jeremy Phillips Bernardo Pollak Anke Reinders Moritz Rövekamp Ryosuke Sano Shinichiro Sawa Marc W Schmid Makoto Shirakawa Roberto Solano Alexander Spunde Noriyuki Suetsugu Sumio Sugano Akifumi Sugiyama Rui Sun Yutaka Suzuki Mizuki Takenaka Daisuke Takezawa Hirokazu Tomogane Masayuki Tsuzuki Takashi Ueda Masaaki Umeda John M Ward Yuichiro Watanabe Kazufumi Yazaki Ryusuke Yokoyama Yoshihiro Yoshitake Izumi Yotsui Sabine Zachgo Jeremy Schmutz

Cell 2017 Oct;171(2):287-304.e15

Department of Energy Joint Genome Institute, Walnut Creek, CA, USA; HudsonAlpha Institute of Biotechnology, Huntsville, AL, USA.

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http://dx.doi.org/10.1016/j.cell.2017.09.030DOI Listing
October 2017

Genomic structure and evolution of the mating type locus in the green seaweed Ulva partita.

Sci Rep 2017 09 15;7(1):11679. Epub 2017 Sep 15.

Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1038/s41598-017-11677-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601483PMC
September 2017

Bm-muted, orthologous to mouse muted and encoding a subunit of the BLOC-1 complex, is responsible for the otm translucent mutation of the silkworm Bombyx mori.

Gene 2017 Sep 30;629:92-100. Epub 2017 Jul 30.

Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.07.071DOI Listing
September 2017

Serotyping dengue virus with isothermal amplification and a portable sequencer.

Sci Rep 2017 06 14;7(1):3510. Epub 2017 Jun 14.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba, 277-8562, Japan.

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http://dx.doi.org/10.1038/s41598-017-03734-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471244PMC
June 2017

Locus-specific ChIP combined with NGS analysis reveals genomic regulatory regions that physically interact with the Pax5 promoter in a chicken B cell line.

DNA Res 2017 Oct;24(5):537-548

Department of Biochemistry and Genome Biology, Hirosaki University Graduate School of Medicine, Hirosaki, Aomori 036-8562, Japan.

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http://dx.doi.org/10.1093/dnares/dsx023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737561PMC
October 2017

Identification of physical interactions between genomic regions by enChIP-Seq.

Genes Cells 2017 Jun 5;22(6):506-520. Epub 2017 May 5.

Chromatin Biochemistry Research Group, Combined Program on Microbiology and Immunology, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0871, Japan.

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http://dx.doi.org/10.1111/gtc.12492DOI Listing
June 2017

Restriction glycosylases: involvement of endonuclease activities in the restriction process.

Nucleic Acids Res 2017 02;45(3):1392-1403

Department of Computational Biology and Medical Sciences (formerly Department of Medical Genome Sciences), Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1093/nar/gkw1250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388411PMC
February 2017

Expression of miR‑26a exhibits a negative correlation with HMGA1 and regulates cancer progression by targeting HMGA1 in lung adenocarcinoma cells.

Mol Med Rep 2017 Feb 15;15(2):534-542. Epub 2016 Dec 15.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108‑8639, Japan.

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https://www.spandidos-publications.com/10.3892/mmr.2016.6053
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http://dx.doi.org/10.3892/mmr.2016.6053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364888PMC
February 2017

Artificial "ping-pong" cascade of PIWI-interacting RNA in silkworm cells.

RNA 2017 01 24;23(1):86-97. Epub 2016 Oct 24.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.

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http://dx.doi.org/10.1261/rna.058875.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159652PMC
January 2017

A missense mutation in solute carrier family 12, member 1 (SLC12A1) causes hydrallantois in Japanese Black cattle.

BMC Genomics 2016 09 9;17(1):724. Epub 2016 Sep 9.

Shirakawa Institute of Animal Genetics, Japan Livestock Technology Association, Odakura, Nishigo, Fukushima, 961-8061, Japan.

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http://dx.doi.org/10.1186/s12864-016-3035-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5016959PMC
September 2016

Comparative Analysis of Genome and Epigenome in Closely Related Medaka Species Identifies Conserved Sequence Preferences for DNA Hypomethylated Domains.

Zoolog Sci 2016 Aug;33(4):358-65

1 Department of Biological Sciences, Graduate School of Science,The University of Tokyo, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.2108/zs160030DOI Listing
August 2016

Allovahlkampfia spelaea Causing Keratitis in Humans.

PLoS Negl Trop Dis 2016 07 14;10(7):e0004841. Epub 2016 Jul 14.

Department of Medical Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1371/journal.pntd.0004841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945048PMC
July 2016

Reminder to deposit DNA sequences.

Science 2016 May 11;352(6287):780. Epub 2016 May 11.

Department of Ecology and Evolution, University of Chicago, Chicago, IL 60637, USA. Beijing Institute of Genomics, Beijing, 100101, China.

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http://dx.doi.org/10.1126/science.aaf7672DOI Listing
May 2016

Local potentiation of stress-responsive genes by upstream noncoding transcription.

Nucleic Acids Res 2016 06 3;44(11):5174-89. Epub 2016 Mar 3.

Department of Life Sciences, The University of Tokyo, Meguro-ku, Tokyo 153-8902, Japan Department of Biological Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033, Japan

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http://dx.doi.org/10.1093/nar/gkw142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914089PMC
June 2016

Oncogenic Fusion Gene CD74-NRG1 Confers Cancer Stem Cell-like Properties in Lung Cancer through a IGF2 Autocrine/Paracrine Circuit.

Cancer Res 2016 Feb 2;76(4):974-83. Epub 2016 Feb 2.

Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan. Division of Molecular Therapy, Institute of Medical Science, University of Tokyo, Tokyo, Japan.

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http://cancerres.aacrjournals.org/content/early/2016/02/02/0
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-2135DOI Listing
February 2016

IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria.

Biochem Biophys Rep 2016 Mar 14;5:191-195. Epub 2015 Dec 14.

Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1016/j.bbrep.2015.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600432PMC
March 2016

Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species.

BMC Genomics 2015 Nov 19;16:978. Epub 2015 Nov 19.

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-0882, Japan.

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http://dx.doi.org/10.1186/s12864-015-2198-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653950PMC
November 2015

A Genome Scan for Genes Underlying Microgeographic-Scale Local Adaptation in a Wild Arabidopsis Species.

PLoS Genet 2015 Jul 14;11(7):e1005361. Epub 2015 Jul 14.

College of Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan; CREST, Japan Science and Technology Agency, Kawaguchi, Saitama, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1005361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501782PMC
July 2015

The Endosymbiotic Bacterium Wolbachia Selectively Kills Male Hosts by Targeting the Masculinizing Gene.

PLoS Pathog 2015 Jul 14;11(7):e1005048. Epub 2015 Jul 14.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1371/journal.ppat.1005048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501725PMC
July 2015

Single-cell analysis of lung adenocarcinoma cell lines reveals diverse expression patterns of individual cells invoked by a molecular target drug treatment.

Genome Biol 2015 Apr 3;16:66. Epub 2015 Apr 3.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, 277-8562, Japan.

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http://dx.doi.org/10.1186/s13059-015-0636-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450998PMC
April 2015

Bombyx mori nucleopolyhedrovirus actin rearrangement-inducing factor 1 enhances systemic infection in B. mori larvae.

J Gen Virol 2015 Jul 25;96(Pt 7):1938-46. Epub 2015 Mar 25.

1Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

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http://dx.doi.org/10.1099/vir.0.000130DOI Listing
July 2015

Dynamic transition of transcription and chromatin landscape during fission yeast adaptation to glucose starvation.

Genes Cells 2015 May 2;20(5):392-407. Epub 2015 Mar 2.

Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Hongo, Tokyo, 113-0033, Japan.

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http://dx.doi.org/10.1111/gtc.12229DOI Listing
May 2015

Detection of APC mosaicism by next-generation sequencing in an FAP patient.

J Hum Genet 2015 May 26;60(5):227-31. Epub 2015 Feb 26.

Division of Clinical Genome Research, Advanced Clinical Research Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1038/jhg.2015.14DOI Listing
May 2015

Sexually biased transcripts at early embryonic stages of the silkworm depend on the sex chromosome constitution.

Gene 2015 Apr 20;560(1):50-6. Epub 2015 Jan 20.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2015.01.036DOI Listing
April 2015

International code of conduct for genomic and health-related data sharing.

Authors:
Sumio Sugano

Hugo J 2014 Dec 14;8(1). Epub 2014 Jun 14.

Department of Medical Genome Sciences, Graduate Scool of Frontier Sciences, The university of Tokyo, 4-6-1, Shirokanedai, 108-8639, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1186/1877-6566-8-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685157PMC
December 2014

Aberrant transcriptional regulations in cancers: genome, transcriptome and epigenome analysis of lung adenocarcinoma cell lines.

Nucleic Acids Res 2014 Dec 6;42(22):13557-72. Epub 2014 Nov 6.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan

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http://academic.oup.com/nar/article/42/22/13557/2411848/Aber
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http://dx.doi.org/10.1093/nar/gku885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267666PMC
December 2014

DBTSS as an integrative platform for transcriptome, epigenome and genome sequence variation data.

Nucleic Acids Res 2015 Jan 5;43(Database issue):D87-91. Epub 2014 Nov 5.

Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

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http://dx.doi.org/10.1093/nar/gku1080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383915PMC
January 2015

Silkworm HP1a transcriptionally enhances highly expressed euchromatic genes via association with their transcription start sites.

Nucleic Acids Res 2014 Oct 18;42(18):11462-71. Epub 2014 Sep 18.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan

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http://dx.doi.org/10.1093/nar/gku862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191426PMC
October 2014

Construction of mate pair full-length cDNAs libraries and characterization of transcriptional start sites and termination sites.

Nucleic Acids Res 2014 17;42(16):e125. Epub 2014 Jul 17.

Graduate School of Frontier Sciences, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan

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http://dx.doi.org/10.1093/nar/gku600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176323PMC
January 2015

Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites.

Genome Med 2014 27;6(6):46. Epub 2014 Jun 27.

Department of Medical Genome Science, Graduate School of Frontier Sciences, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://dx.doi.org/10.1186/gm568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097847PMC
July 2014

Occupancy of tissue-specific cis-regulatory modules by Otx2 and TLE/Groucho for embryonic head specification.

Nat Commun 2014 Jul 9;5:4322. Epub 2014 Jul 9.

Department of Biological Sciences, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

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http://dx.doi.org/10.1038/ncomms5322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4805429PMC
July 2014

Perturbation of copper homeostasis is instrumental in early developmental arrest of intraerythrocytic Plasmodium falciparum.

BMC Microbiol 2014 Jun 24;14:167. Epub 2014 Jun 24.

Department of Parasitology, National Institute of Infectious Diseases, 23-1 Toyama 1-chome, Shinjuku-ku, Tokyo 162-8640, Japan.

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http://dx.doi.org/10.1186/1471-2180-14-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080775PMC
June 2014

RNA sequencing: from sample preparation to analysis.

Methods Mol Biol 2014 ;1164:51-65

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba, 277-8562, Japan.

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http://dx.doi.org/10.1007/978-1-4939-0805-9_6DOI Listing
January 2015

Large hypomethylated domains serve as strong repressive machinery for key developmental genes in vertebrates.

Development 2014 Jul 12;141(13):2568-80. Epub 2014 Jun 12.

Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan

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http://dx.doi.org/10.1242/dev.108548DOI Listing
July 2014

A single female-specific piRNA is the primary determiner of sex in the silkworm.

Nature 2014 May 14;509(7502):633-6. Epub 2014 May 14.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.

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http://dx.doi.org/10.1038/nature13315DOI Listing
May 2014

A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.

PLoS One 2014 21;9(4):e95374. Epub 2014 Apr 21.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, the University of Tokyo, Kashiwa, Chiba, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095374PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994037PMC
January 2015

Methylome diversification through changes in DNA methyltransferase sequence specificity.

PLoS Genet 2014 Apr 10;10(4):e1004272. Epub 2014 Apr 10.

Department of Medical Genome Sciences, Graduate School of Frontier Sciences, University of Tokyo, Minato-ku, Tokyo, Japan; Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1004272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983042PMC
April 2014

CLOCK-controlled polyphonic regulation of circadian rhythms through canonical and noncanonical E-boxes.

Mol Cell Biol 2014 May 3;34(10):1776-87. Epub 2014 Mar 3.

Department of Biophysics and Biochemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1128/MCB.01465-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019033PMC
May 2014

Cross-boundary cancer studies at the University of Tokyo: Using genome science to decipher cancer in Asia.

Authors:
Sumio Sugano

Jpn J Clin Oncol 2014 Feb;44 Suppl 1:i17-21

please contact Hideyuki Akaza, MD, Department of Strategic Investigation on Comprehensive Cancer, Network Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

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http://dx.doi.org/10.1093/jjco/hyt221DOI Listing
February 2014

Regulations of ABCB1 and ABCG2 expression through MAPK pathways in acute lymphoblastic leukemia cell lines.

Anticancer Res 2013 Dec;33(12):5317-23

Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

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December 2013

Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes.

Nat Commun 2013 ;4:2850

1] Department of Molecular and Cellular Biochemistry, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan [2].

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http://dx.doi.org/10.1038/ncomms3850DOI Listing
October 2014

Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.

J Exp Med 2013 Nov 11;210(12):2627-39. Epub 2013 Nov 11.

Department of Cellular and Molecular Medicine and 2 Department of Clinical Cell Biology and Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

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http://dx.doi.org/10.1084/jem.20131144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832936PMC
November 2013

Molecular basis of wing coloration in a Batesian mimic butterfly, Papilio polytes.

Sci Rep 2013 Nov 11;3:3184. Epub 2013 Nov 11.

Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba 277-8562, Japan.

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http://dx.doi.org/10.1038/srep03184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822385PMC
November 2013

Giardia lamblia transcriptome analysis using TSS-Seq and RNA-Seq.

PLoS One 2013 7;8(10):e76184. Epub 2013 Oct 7.

Department of Medical Genomics, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan ; Department of Parasitology, Faculty of Medicine, Assiut University, Assiut, Egypt.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792122PMC
August 2014

Screening of novel malaria DNA vaccine candidates using full-length cDNA library.

Exp Parasitol 2013 Nov 17;135(3):546-50. Epub 2013 Sep 17.

Department of Medical Genomics, Graduate School of Frontier Sciences, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan; Research Institute for Biological Sciences, Tokyo University of Science, 2669 Yamazaki, Noda, Chiba 278-0022, Japan; Laboratory of Systems Biology, Center for Experimental Medicine and Systems Biology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exppara.2013.09.007DOI Listing
November 2013

Screening for possible miRNA-mRNA associations in a colon cancer cell line.

Gene 2014 Jan 9;533(2):520-31. Epub 2013 Aug 9.

Graduate School of Frontier Sciences, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8562, Japan.

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http://dx.doi.org/10.1016/j.gene.2013.08.005DOI Listing
January 2014

Characterization of a novel chromodomain-containing gene from the silkworm, Bombyx mori.

Gene 2013 Sep 11;527(2):649-54. Epub 2013 Jul 11.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.

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http://dx.doi.org/10.1016/j.gene.2013.06.071DOI Listing
September 2013

Characterization of the mitochondrial genome of Rousettus leschenaulti.

Mitochondrial DNA 2014 Dec 2;25(6):443-4. Epub 2013 Jul 2.

Laboratory of Bioinformatics, Adam Mickiewicz University , Poznan , Poland .

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http://www.tandfonline.com/doi/full/10.3109/19401736.2013.80
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http://dx.doi.org/10.3109/19401736.2013.809451DOI Listing
December 2014

Hsp90 facilitates accurate loading of precursor piRNAs into PIWI proteins.

RNA 2013 Jul 16;19(7):896-901. Epub 2013 May 16.

Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.

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http://dx.doi.org/10.1261/rna.037200.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683924PMC
July 2013

The comprehensive epigenome map of piRNA clusters.

Nucleic Acids Res 2013 Feb 20;41(3):1581-90. Epub 2012 Dec 20.

Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Yayoi, Tokyo, Japan.

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http://dx.doi.org/10.1093/nar/gks1275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561999PMC
February 2013