Suhwan Chang

Suhwan Chang

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Suhwan Chang

Suhwan Chang

Publications by authors named "Suhwan Chang"

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48Publications

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A CRISPR-based base-editing screen for the functional assessment of BRCA1 variants.

Oncogene 2020 Jan 29;39(1):30-35. Epub 2019 Aug 29.

Department of Biomedical Sciences, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

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http://dx.doi.org/10.1038/s41388-019-0968-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937211PMC
January 2020

A pharmacogenomic analysis using L1000CDS identifies BX-795 as a potential anticancer drug for primary pancreatic ductal adenocarcinoma cells.

Cancer Lett 2019 Nov 9;465:82-93. Epub 2019 Aug 9.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Republic of Korea; Department of Physiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2019.08.002DOI Listing
November 2019

PLGA Nanoparticles Codelivering siRNAs against Programmed Cell Death Protein-1 and Its Ligand Gene for Suppression of Colon Tumor Growth.

Mol Pharm 2019 Nov 7. Epub 2019 Nov 7.

Center for Theragnosis, Biomedical Research Institute , Korea Institute of Science and Technology , Seoul 02792 , South Korea.

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http://dx.doi.org/10.1021/acs.molpharmaceut.9b00826DOI Listing
November 2019

The Role of miRNAs in Immune Cell Development, Immune Cell Activation, and Tumor Immunity: With a Focus on Macrophages and Natural Killer Cells.

Cells 2019 Sep 24;8(10). Epub 2019 Sep 24.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul 05505, Korea.

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http://dx.doi.org/10.3390/cells8101140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829453PMC
September 2019

Cellular context-dependent interaction between cancer and stellate cells in hetero-type multicellular spheroids of pancreatic tumor.

Biochem Biophys Res Commun 2019 Jul 24;515(1):183-189. Epub 2019 May 24.

Department of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul, Republic of Korea; Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.05.101DOI Listing
July 2019

Three Dimensional Mixed-Cell Spheroids Mimic Stroma-Mediated Chemoresistance and Invasive Migration in hepatocellular carcinoma.

Neoplasia 2018 08 4;20(8):800-812. Epub 2018 Jul 4.

Department of Medical Life Sciences, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034588PMC
August 2018

Construction of Multi-Potent MicroRNA Sponge and Its Functional Evaluation.

Authors:
Suhwan Chang

Methods Mol Biol 2018 ;1699:201-209

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, South Korea.

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http://dx.doi.org/10.1007/978-1-4939-7435-1_15DOI Listing
July 2018

Combinatory RNA-Sequencing Analyses Reveal a Dual Mode of Gene Regulation by ADAR1 in Gastric Cancer.

Dig Dis Sci 2018 07 25;63(7):1835-1850. Epub 2018 Apr 25.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul, 05505, Korea.

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http://dx.doi.org/10.1007/s10620-018-5081-9DOI Listing
July 2018

Integrative Bioinformatics and Functional Analyses of GEO, ENCODE, and TCGA Reveal FADD as a Direct Target of the Tumor Suppressor BRCA1.

Int J Mol Sci 2018 May 14;19(5). Epub 2018 May 14.

Department of Biomedical Sciences, University of Ulsan School of Medicine, Asan Medical Center, Seoul 05505, Korea.

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http://dx.doi.org/10.3390/ijms19051458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983697PMC
May 2018

BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage.

Nat Commun 2018 02 7;9(1):537. Epub 2018 Feb 7.

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD, 21702, USA.

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http://dx.doi.org/10.1038/s41467-018-03020-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803202PMC
February 2018

The Generation and Application of Patient-Derived Xenograft Model for Cancer Research.

Cancer Res Treat 2018 Jan 13;50(1):1-10. Epub 2017 Sep 13.

Department of Biomedical Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.4143/crt.2017.307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784646PMC
January 2018

Genetic and metabolic comparison of orthotopic and heterotopic patient-derived pancreatic-cancer xenografts to the original patient tumors.

Oncotarget 2018 Jan 21;9(8):7867-7881. Epub 2017 Dec 21.

Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, South Korea.

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http://dx.doi.org/10.18632/oncotarget.23567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814265PMC
January 2018

Development of Novel Therapeutic Agents by Inhibition of Oncogenic MicroRNAs.

Int J Mol Sci 2017 Dec 27;19(1). Epub 2017 Dec 27.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.

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http://www.mdpi.com/1422-0067/19/1/65
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http://dx.doi.org/10.3390/ijms19010065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796015PMC
December 2017

A Novel Germline Mutation in Causes Exon 20 Skipping in a Korean Family with a History of Breast Cancer.

J Breast Cancer 2017 Sep 22;20(3):310-313. Epub 2017 Sep 22.

Department of System Cancer Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.

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http://dx.doi.org/10.4048/jbc.2017.20.3.310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5620447PMC
September 2017

Use of Dimethyl Pimelimidate with Microfluidic System for Nucleic Acids Extraction without Electricity.

Anal Chem 2017 07 5;89(14):7502-7510. Epub 2017 Jul 5.

Department of Convergence Medicine, Asan Medical Center, University of Ulsan College of Medicine Biomedical Engineering Research Center, Asan Institute of Life Sciences, Asan Medical Center , 88 Olympicro-43gil, Songpa-gu, Seoul 05505, Republic of Korea.

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http://dx.doi.org/10.1021/acs.analchem.7b01193DOI Listing
July 2017

ADAR1 and MicroRNA; A Hidden Crosstalk in Cancer.

Int J Mol Sci 2017 Apr 11;18(4). Epub 2017 Apr 11.

Department of Biomedical Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.

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http://dx.doi.org/10.3390/ijms18040799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412383PMC
April 2017

Quantitative structural characterization of phosphatidylinositol phosphates from biological samples.

J Lipid Res 2017 02 9;58(2):469-478. Epub 2016 Dec 9.

Biomedical Research Center, Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea

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http://dx.doi.org/10.1194/jlr.D069989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282945PMC
February 2017

Glutamate release inhibitor, Riluzole, inhibited proliferation of human hepatocellular carcinoma cells by elevated ROS production.

Cancer Lett 2016 11 6;382(2):157-165. Epub 2016 Sep 6.

Asan Institute for Life Science, Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.08.028DOI Listing
November 2016

Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1.

Cancer Lett 2016 Mar 23;372(1):24-35. Epub 2015 Dec 23.

Asan Institute for Life Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744505PMC
March 2016

Loss of oncogenic miR-155 in tumor cells promotes tumor growth by enhancing C/EBP-β-mediated MDSC infiltration.

Oncotarget 2016 Mar;7(10):11094-112

Department of Biomedical Sciences, Department of Physiology, University of Ulsan School of Medicine, Seoul, South Korea.

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http://dx.doi.org/10.18632/oncotarget.7150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905460PMC
March 2016

Surgical and Oncological Factors Affecting the Successful Engraftment of Patient-derived Xenografts in Pancreatic Ductal Adenocarcinoma.

Anticancer Res 2016 Feb;36(2):517-21

Departments of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Songpa-gu, Seoul, Republic of Korea Asan Institute for Life Sciences, University of Ulsan College of Medicine and Asan Medical Center, Songpa-gu, Seoul, Republic of Korea

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February 2016

Simultaneous inhibition of multiple oncogenic miRNAs by a multi-potent microRNA sponge.

Oncotarget 2015 Aug;6(24):20370-87

Department of Biomedical Sciences, University of Ulsan School of Medicine, Seoul 138-736, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653011PMC
http://dx.doi.org/10.18632/oncotarget.4827DOI Listing
August 2015

Bioinformatic and metabolomic analysis reveals miR-155 regulates thiamine level in breast cancer.

Cancer Lett 2015 Feb 4;357(2):488-97. Epub 2014 Dec 4.

Department of Biomedical Sciences, Department of Physiology, University of Ulsan College of Medicine, Seoul, South Korea; Asan Medical Center, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2014.11.058DOI Listing
February 2015

A PAUF-neutralizing antibody targets both carcinoma and endothelial cells to impede pancreatic tumor progression and metastasis.

Biochem Biophys Res Commun 2014 Nov 18;454(1):144-50. Epub 2014 Oct 18.

Immunotherapy Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South Korea; Department of Biological Sciences, Dong-A University, Busan, South Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X140185
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http://dx.doi.org/10.1016/j.bbrc.2014.10.056DOI Listing
November 2014

Development and characterization of a colon PDX model that reproduces drug responsiveness and the mutation profiles of its original tumor.

Cancer Lett 2014 Apr 11;345(1):56-64. Epub 2013 Dec 11.

Asan Institute for Life Science, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea; Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2013.11.010DOI Listing
April 2014

pH-rate profiles of L-arabinitol 4-dehydrogenase from Hypocrea jecorina and its application in L-xylulose production.

Bioorg Med Chem Lett 2014 Jan 27;24(1):173-6. Epub 2013 Nov 27.

Department of Chemical Engineering, Konkuk University, Seoul 143-701, Republic of Korea; Institute of SK-KU Biomaterials, Konkuk University, Seoul 143-701, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X130133
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http://dx.doi.org/10.1016/j.bmcl.2013.11.047DOI Listing
January 2014

The role of epigenetic transcriptional regulation in BRCA1-mediated tumor suppression.

Transcription 2013 Jan-Feb;4(1):24-8. Epub 2012 Nov 6.

Dept. of Medicine, Graduate School, University of Ulsan College of Medicine, Asan Institute for Life Science, Songpa-gu, Seoul, Republic of Korea.

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http://www.tandfonline.com/doi/abs/10.4161/trns.22600
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644038PMC
http://dx.doi.org/10.4161/trns.22600DOI Listing
July 2013

BRCA1 and microRNAs: emerging networks and potential therapeutic targets.

Mol Cells 2012 Nov 24;34(5):425-32. Epub 2012 Jul 24.

Mouse Cancer Genetics Program, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1007/s10059-012-0118-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887789PMC
November 2012

Using recombineering to generate point mutations: the oligonucleotide-based "hit and fix" method.

Methods Mol Biol 2012 ;852:111-20

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA.

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http://link.springer.com/10.1007/978-1-61779-564-0_9
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http://dx.doi.org/10.1007/978-1-61779-564-0_9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668621PMC
May 2012

Functional analysis of human BRCA2 variants using a mouse embryonic stem cell-based assay.

Methods Mol Biol 2010 ;653:259-80

Center for Cancer Research, Mouse Cancer Genetics Program, National Cancer Institute at Frederick, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-60761-759-4_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669890PMC
December 2010

Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations.

J Clin Invest 2009 Oct 21;119(10):3160-71. Epub 2009 Sep 21.

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute at Frederick, 1050 Boyles Street, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1172/JCI39836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2752086PMC
October 2009

Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications.

Cancer Res 2008 Dec;68(23):9973-81

Mouse Cancer Genetics Program, Center for Cancer Research, and Pathology Histotechnology Laboratory, Science Applications International Corporation-Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729200PMC
December 2008

A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.

Proc Natl Acad Sci U S A 2005 Feb 7;102(7):2608-13. Epub 2005 Feb 7.

Department of Neurobiology and Physiology, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA.

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http://dx.doi.org/10.1073/pnas.0409763102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548324PMC
February 2005

p62 forms a ternary complex with PKCzeta and PAR-4 and antagonizes PAR-4-induced PKCzeta inhibition.

FEBS Lett 2002 Jan;510(1-2):57-61

School of Medicine, Sunkyunkwan University, 300 ChunChun-Dong, Jangan-Gu, Suwon, Kyonggi-Do, South Korea.

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http://dx.doi.org/10.1016/s0014-5793(01)03224-0DOI Listing
January 2002