Suet Yi Leung

Suet Yi Leung

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Suet Yi Leung

Suet Yi Leung

Publications by authors named "Suet Yi Leung"

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Breakthrough Moments: Organoid Models of Cancer.

Cell Stem Cell 2019 Jun;24(6):839-840

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong; The Jockey Club Centre for Clinical Innovation and Discovery, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.05.006DOI Listing
June 2019

A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening.

Cell Stem Cell 2018 12 18;23(6):882-897.e11. Epub 2018 Oct 18.

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong; The Jockey Club Centre for Clinical Innovation and Discovery, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909183048
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http://dx.doi.org/10.1016/j.stem.2018.09.016DOI Listing
December 2018

PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation.

Cell Rep 2018 Oct;25(3):690-701.e8

School of Biomedical Sciences, University of Hong Kong, Pokfulam, Hong Kong, China; State Key Laboratory for Liver Research, University of Hong Kong, Pokfulam, Hong Kong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183149
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http://dx.doi.org/10.1016/j.celrep.2018.09.053DOI Listing
October 2018

RNF43 germline and somatic mutation in serrated neoplasia pathway and its association with BRAF mutation.

Gut 2017 09 21;66(9):1645-1656. Epub 2016 Jun 21.

Hereditary Gastrointestinal Cancer Genetic Diagnosis Laboratory, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1136/gutjnl-2016-311849DOI Listing
September 2017

Genomics Study of Gastric Cancer and Its Molecular Subtypes.

Adv Exp Med Biol 2016;908:419-39

Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Pok Fu Lam, Hong Kong.

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http://dx.doi.org/10.1007/978-3-319-41388-4_21DOI Listing
January 2017

A mutational signature in gastric cancer suggests therapeutic strategies.

Nat Commun 2015 Oct 29;6:8683. Epub 2015 Oct 29.

Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/ncomms9683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4918743PMC
October 2015

Integration of DNA copy number alterations and transcriptional expression analysis in human gastric cancer.

PLoS One 2012 23;7(4):e29824. Epub 2012 Apr 23.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029824PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335165PMC
September 2012

Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development.

Gastroenterology 2010 Sep 11;139(3):893-903. Epub 2010 Jun 11.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930094PMC
September 2010

Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma.

Clin Cancer Res 2009 Sep 8;15(18):5878-87. Epub 2009 Sep 8.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745503PMC
September 2009

Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.

Gastroenterology 2009 Jul 18;137(1):176-87. Epub 2009 Mar 18.

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1053/j.gastro.2009.03.005DOI Listing
July 2009

A 33-year-old Chinese woman with a left frontal tumor.

Brain Pathol 2009 Apr;19(2):337-40

Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1111/j.1750-3639.2009.00277.xDOI Listing
April 2009

Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors.

Proc Natl Acad Sci U S A 2007 Sep 19;104(39):15418-23. Epub 2007 Sep 19.

Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1073/pnas.0707210104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000506PMC
September 2007

Cell cycle-related kinase: a novel candidate oncogene in human glioblastoma.

J Natl Cancer Inst 2007 Jun 12;99(12):936-48. Epub 2007 Jun 12.

Department of Chemistry, Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1093/jnci/djm011DOI Listing
June 2007

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

Gastroenterology 2006 Dec 1;131(6):1835-43. Epub 2006 Oct 1.

Department of Gastroenterology, Rui-jin Hospital, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1053/j.gastro.2006.09.050DOI Listing
December 2006

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.

Nat Genet 2006 Oct 3;38(10):1178-83. Epub 2006 Sep 3.

Hereditary Gastrointestinal Cancer Genetic Diagnosis Laboratory, Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1038/ng1866DOI Listing
October 2006

Comprehensive analysis of 19q12 amplicon in human gastric cancers.

Mod Pathol 2006 Jun;19(6):854-63

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1038/modpathol.3800593DOI Listing
June 2006

Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours.

Carcinogenesis 2006 Mar 4;27(3):454-64. Epub 2005 Nov 4.

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1093/carcin/bgi259DOI Listing
March 2006

EFA6A enhances glioma cell invasion through ADP ribosylation factor 6/extracellular signal-regulated kinase signaling.

Cancer Res 2006 Feb;66(3):1583-90

Department of Chemistry, Open Laboratory of Chemical Biology, Institute of Molecular Technology for Drug Discovery and Synthesis, University of Hong Kong, Pokfulam Road, Hong Kong, China.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2424DOI Listing
February 2006

A gene expression signature of genetic instability in colon cancer.

Cancer Res 2005 Oct;65(20):9200-5

Department of Pathology, Stanford University, Stanford, CA 94305-5176, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-4163DOI Listing
October 2005

Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats.

Proc Natl Acad Sci U S A 2005 Sep 16;102(39):14040-5. Epub 2005 Sep 16.

Department of Microbiology, Research Centre of Infection and Immunology, State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0506735102
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http://dx.doi.org/10.1073/pnas.0506735102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1236580PMC
September 2005

Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E.

J Virol 2005 May;79(10):6180-93

Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Center of Infection and Immunology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1128/JVI.79.10.6180-6193.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1091719PMC
May 2005

CDX2 co-localizes with liver-intestine cadherin in intestinal metaplasia and adenocarcinoma of the stomach.

J Pathol 2005 Apr;205(5):615-22

Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1002/path.1741DOI Listing
April 2005

Mutations of PIK3CA in gastric adenocarcinoma.

BMC Cancer 2005 Mar 23;5:29. Epub 2005 Mar 23.

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1186/1471-2407-5-29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079799PMC
March 2005

Diverse proteomic alterations in gastric adenocarcinoma.

Proteomics 2004 Oct;4(10):3276-87

Department of Chemistry, University of Hong Kong, China.

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http://dx.doi.org/10.1002/pmic.200300916DOI Listing
October 2004

Expression profiling identifies chemokine (C-C motif) ligand 18 as an independent prognostic indicator in gastric cancer.

Gastroenterology 2004 Aug;127(2):457-69

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, China.

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http://dx.doi.org/10.1053/j.gastro.2004.05.031DOI Listing
August 2004

Helicobacter pylori infection is associated with increased expression of macrophage migratory inhibitory factor--by epithelial cells, T cells, and macrophages--in gastric mucosa.

J Infect Dis 2004 Jul 21;190(2):293-302. Epub 2004 Jun 21.

Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, S.A.R., China.

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http://dx.doi.org/10.1086/421915DOI Listing
July 2004

Overexpression of LI-cadherin in gastric cancer is associated with lymph node metastasis.

Biochem Biophys Res Commun 2004 Jun;319(2):562-8

Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.197DOI Listing
June 2004

De novo sarcoma of donor origin in a liver allograft determined by microsatellite analysis: a short report.

Liver Transpl 2004 Feb;10(2):320-3

Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1002/lt.20063DOI Listing
February 2004

Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.

Oncogene 2003 Oct;22(44):6946-53

Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1038/sj.onc.1206799DOI Listing
October 2003

N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation.

Int J Cancer 2003 Sep;106(3):342-7

Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, China.

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http://dx.doi.org/10.1002/ijc.11228DOI Listing
September 2003

Cigarette smoke exposure increases ulcerative colitis-associated colonic adenoma formation in mice.

Carcinogenesis 2003 Aug 5;24(8):1407-13. Epub 2003 Jun 5.

Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1093/carcin/bgg094DOI Listing
August 2003

Comprehensive analysis of the gene expression profiles in human gastric cancer cell lines.

Oncogene 2002 Sep;21(42):6549-56

Department of Surgery, Beijing Cancer Hospital, Peking University School of Oncology, Beijing, China.

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http://www.nature.com/articles/1205829
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http://dx.doi.org/10.1038/sj.onc.1205829DOI Listing
September 2002