Publications by authors named "Sudhir Kumar Kale"

3 Publications

  • Page 1 of 1

Added value of strain elastography in the characterisation of breast lesions: A prospective study.

Ultrasound 2020 Aug 16;28(3):164-173. Epub 2020 Mar 16.

Department of Radio Diagnosis, Aster CMI Hospital, Bengaluru, India.

Background: Elastography is a new promising ultrasonographic technique which is used to differentiate benign and malignant breast lesions based on the stiffness of the lesion.

Purpose: To determine the role of strain elastography in characterisation of breast lesions and to compare the diagnostic performances of strain elastography and conventional ultrasound (US).

Methods: In total, 113 breast lesions in 100 women were prospectively evaluated by US and strain elastography followed by the histopathological examination. Elastography score based on the Tsukuba colour scale and strain ratio were determined for each lesion. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value were calculated for each modality and the diagnostic performances were compared. The best cut-off point was calculated for each of the elastography parameters using the receiver operator curve analysis.

Results: Out of the 113 lesions, 40 were malignant (35.4%) and 73 were benign (64.6%). The area under the curve for elastography score showed significant difference with that of US: 0.98 versus 0.90 (Difference = 0.08, =0.02). The elastography parameters were more specific as compared to US (ES-95 and SR-93% vs. 63%,  < 0.05) with a high negative predictive value. The combined use of elastography and US gave better results with 95% sensitivity, 94% specificity, 94% accuracy and negative predictive value reaching 97%.

Conclusion: Strain elastography is a useful adjunct to conventional ultrasonography. The combined use of strain elastography and ultrasound improves the characterisation of breast lesions and helps in down-staging of assigned BI-RADS category, thereby avoiding unnecessary biopsies. ES is the most useful elastography parameter to differentiate between benign and malignant breast lesions.
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August 2020

Fibrosing mediastinitis mimicking as chronic pulmonary thromboembolism.

BJR Case Rep 2020 Mar 12;6(1):20190049. Epub 2020 Feb 12.

Department of Radiology, Aster CMI Hospital, Bangalore, India.

Fibrosing mediastinitis is an uncommon, benign, progressive disorder caused by proliferation of fibrous tissue within mediastinum resulting in encasement of vital mediastinal broncho-vascular structures. Due to its rarity and variable clinical presentation, it is often misdiagnosed. We are presenting a case of fibrosing mediastinitis in an Ethiopian origin young male presenting with pulmonary hypertension due to simultaneous occlusion of pulmonary vein and arteries, clinically misdiagnosed as chronic pulmonary thromboembolism.
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March 2020

Extramammary orbital myofibroblastoma: a rare orbital tumor.

Orbit 2021 Feb 8;40(1):55-59. Epub 2020 Jan 8.

Department of Pathology, Aster CMI Hospital , Bangalore, India.

Extra-mammary myofibroblastomas are rare benign mesenchymal neoplasms, histologically and immune-phenotypically identical to mammary myofibroblastomas. Histologically, they are characterized by the abundance of spindle cells in hyalinized collagenous stroma with positive expression of CD 34 and desmin. We present an extremely rare case of extra-mammary myofibroblastoma of the orbit in a 29-year - old male who presented with painless proptosis of the right eye, with a description of clinical, radiological, and histological findings.
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February 2021