Sudha K Iyengar

Sudha K Iyengar

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Sudha K Iyengar

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Diversity of Ocular Surface Bacterial Microbiome Adherent to Worn Contact Lenses and Bacterial Communities Associated With Care Solution Use.

Eye Contact Lens 2019 Sep;45(5):331-339

Department of Dermatology (M.A.R, P.K.M., M.A.G.), Center for Medical Mycology, Case Western Reserve University, Cleveland, OH; Department of Ophthalmology and Visual Sciences (L.S.-F.), University Hospitals Eye Institute, University Hospitals Cleveland Medical Center, Cleveland, OH; and Department of Population and Quantitative Health Sciences (S.D., S.K.I., B.R., M.C.), Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1097/ICL.0000000000000578DOI Listing
September 2019

Reading Outcomes for Individuals With Histories of Suspected Childhood Apraxia of Speech.

Am J Speech Lang Pathol 2019 Aug 16:1-16. Epub 2019 Aug 16.

Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1044/2019_AJSLP-18-0132DOI Listing
August 2019

Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.

Diabetes 2019 02 28;68(2):441-456. Epub 2018 Nov 28.

Massachusetts Eye and Ear Department of Ophthalmology, Harvard Medical School, Boston, MA

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http://dx.doi.org/10.2337/db18-0567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341299PMC
February 2019

Aldose Reductase Polymorphisms, Fasting Blood Glucose, and Age-Related Cortical Cataract.

Invest Ophthalmol Vis Sci 2018 09;59(11):4755-4762

Centre for Vision Research, Department of Ophthalmology, The Westmead Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.

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http://dx.doi.org/10.1167/iovs.18-24353DOI Listing
September 2018

Exome Array Analysis of Nuclear Lens Opacity.

Ophthalmic Epidemiol 2018 06 28;25(3):215-219. Epub 2017 Nov 28.

a Department of Epidemiology , Johns Hopkins Bloomberg School of Public Health , Baltimore , MD , USA.

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http://dx.doi.org/10.1080/09286586.2017.1406122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851868PMC
June 2018

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.

Authors:
Milly S Tedja Robert Wojciechowski Pirro G Hysi Nicholas Eriksson Nicholas A Furlotte Virginie J M Verhoeven Adriana I Iglesias Magda A Meester-Smoor Stuart W Tompson Qiao Fan Anthony P Khawaja Ching-Yu Cheng René Höhn Kenji Yamashiro Adam Wenocur Clare Grazal Toomas Haller Andres Metspalu Juho Wedenoja Jost B Jonas Ya Xing Wang Jing Xie Paul Mitchell Paul J Foster Barbara E K Klein Ronald Klein Andrew D Paterson S Mohsen Hosseini Rupal L Shah Cathy Williams Yik Ying Teo Yih Chung Tham Preeti Gupta Wanting Zhao Yuan Shi Woei-Yuh Saw E-Shyong Tai Xue Ling Sim Jennifer E Huffman Ozren Polašek Caroline Hayward Goran Bencic Igor Rudan James F Wilson Peter K Joshi Akitaka Tsujikawa Fumihiko Matsuda Kristina N Whisenhunt Tanja Zeller Peter J van der Spek Roxanna Haak Hanne Meijers-Heijboer Elisabeth M van Leeuwen Sudha K Iyengar Jonathan H Lass Albert Hofman Fernando Rivadeneira André G Uitterlinden Johannes R Vingerling Terho Lehtimäki Olli T Raitakari Ginevra Biino Maria Pina Concas Tae-Hwi Schwantes-An Robert P Igo Gabriel Cuellar-Partida Nicholas G Martin Jamie E Craig Puya Gharahkhani Katie M Williams Abhishek Nag Jugnoo S Rahi Phillippa M Cumberland Cécile Delcourt Céline Bellenguez Janina S Ried Arthur A Bergen Thomas Meitinger Christian Gieger Tien Yin Wong Alex W Hewitt David A Mackey Claire L Simpson Norbert Pfeiffer Olavi Pärssinen Paul N Baird Veronique Vitart Najaf Amin Cornelia M van Duijn Joan E Bailey-Wilson Terri L Young Seang-Mei Saw Dwight Stambolian Stuart MacGregor Jeremy A Guggenheim Joyce Y Tung Christopher J Hammond Caroline C W Klaver

Nat Genet 2018 06 28;50(6):834-848. Epub 2018 May 28.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://www.nature.com/articles/s41588-018-0127-7
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http://dx.doi.org/10.1038/s41588-018-0127-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980758PMC
June 2018

Variation in PTCHD2, CRISP3, NAP1L4, FSCB, and AP3B2 associated with spherical equivalent.

Mol Vis 2016 14;22:783-96. Epub 2016 Jul 14.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Department of Pathology, Johns Hopkins School of Medicine, Baltimore, MD.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945165PMC
January 2018

Psychosocial co-morbidities in adolescents and adults with histories of communication disorders.

J Commun Disord 2016 May-Jun;61:60-70. Epub 2016 Mar 18.

Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States.

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http://dx.doi.org/10.1016/j.jcomdis.2016.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880534PMC
November 2017

Associations Between Methylenetetrahydrofolate Reductase Polymorphisms, Serum Homocysteine Levels, and Incident Cortical Cataract.

JAMA Ophthalmol 2016 May;134(5):522-528

Centre for Vision Research, Department of Ophthalmology, The Westmead Institute for Medical Research, The University of Sydney, Westmead Hospital, Westmead, New South Wales, Australia.

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http://dx.doi.org/10.1001/jamaophthalmol.2016.0167DOI Listing
May 2016

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.

Authors:
Qiao Fan Virginie J M Verhoeven Robert Wojciechowski Veluchamy A Barathi Pirro G Hysi Jeremy A Guggenheim René Höhn Veronique Vitart Anthony P Khawaja Kenji Yamashiro S Mohsen Hosseini Terho Lehtimäki Yi Lu Toomas Haller Jing Xie Cécile Delcourt Mario Pirastu Juho Wedenoja Puya Gharahkhani Cristina Venturini Masahiro Miyake Alex W Hewitt Xiaobo Guo Johanna Mazur Jenifer E Huffman Katie M Williams Ozren Polasek Harry Campbell Igor Rudan Zoran Vatavuk James F Wilson Peter K Joshi George McMahon Beate St Pourcain David M Evans Claire L Simpson Tae-Hwi Schwantes-An Robert P Igo Alireza Mirshahi Audrey Cougnard-Gregoire Céline Bellenguez Maria Blettner Olli Raitakari Mika Kähönen Ilkka Seppala Tanja Zeller Thomas Meitinger Janina S Ried Christian Gieger Laura Portas Elisabeth M van Leeuwen Najaf Amin André G Uitterlinden Fernando Rivadeneira Albert Hofman Johannes R Vingerling Ya Xing Wang Xu Wang Eileen Tai-Hui Boh M Kamran Ikram Charumathi Sabanayagam Preeti Gupta Vincent Tan Lei Zhou Candice E H Ho Wan'e Lim Roger W Beuerman Rosalynn Siantar E-Shyong Tai Eranga Vithana Evelin Mihailov Chiea-Chuen Khor Caroline Hayward Robert N Luben Paul J Foster Barbara E K Klein Ronald Klein Hoi-Suen Wong Paul Mitchell Andres Metspalu Tin Aung Terri L Young Mingguang He Olavi Pärssinen Cornelia M van Duijn Jie Jin Wang Cathy Williams Jost B Jonas Yik-Ying Teo David A Mackey Konrad Oexle Nagahisa Yoshimura Andrew D Paterson Norbert Pfeiffer Tien-Yin Wong Paul N Baird Dwight Stambolian Joan E Bailey Wilson Ching-Yu Cheng Christopher J Hammond Caroline C W Klaver Seang-Mei Saw Jugnoo S Rahi Jean-François Korobelnik John P Kemp Nicholas J Timpson George Davey Smith Jamie E Craig Kathryn P Burdon Rhys D Fogarty Sudha K Iyengar Emily Chew Sarayut Janmahasatian Nicholas G Martin Stuart MacGregor Liang Xu Maria Schache Vinay Nangia Songhomitra Panda-Jonas Alan F Wright Jeremy R Fondran Jonathan H Lass Sheng Feng Jing Hua Zhao Kay-Tee Khaw Nick J Wareham Taina Rantanen Jaakko Kaprio Chi Pui Pang Li Jia Chen Pancy O Tam Vishal Jhanji Alvin L Young Angela Döring Leslie J Raffel Mary-Frances Cotch Xiaohui Li Shea Ping Yip Maurice K H Yap Ginevra Biino Simona Vaccargiu Maurizio Fossarello Brian Fleck Seyhan Yazar Jan Willem L Tideman Milly Tedja Margaret M Deangelis Margaux Morrison Lindsay Farrer Xiangtian Zhou Wei Chen Nobuhisa Mizuki Akira Meguro Kari Matti Mäkelä

Nat Commun 2016 Mar 29;7:11008. Epub 2016 Mar 29.

Department of Ophthalmology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ncomms11008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820539PMC
March 2016

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.

Authors:
Lars G Fritsche Wilmar Igl Jessica N Cooke Bailey Felix Grassmann Sebanti Sengupta Jennifer L Bragg-Gresham Kathryn P Burdon Scott J Hebbring Cindy Wen Mathias Gorski Ivana K Kim David Cho Donald Zack Eric Souied Hendrik P N Scholl Elisa Bala Kristine E Lee David J Hunter Rebecca J Sardell Paul Mitchell Joanna E Merriam Valentina Cipriani Joshua D Hoffman Tina Schick Yara T E Lechanteur Robyn H Guymer Matthew P Johnson Yingda Jiang Chloe M Stanton Gabriëlle H S Buitendijk Xiaowei Zhan Alan M Kwong Alexis Boleda Matthew Brooks Linn Gieser Rinki Ratnapriya Kari E Branham Johanna R Foerster John R Heckenlively Mohammad I Othman Brendan J Vote Helena Hai Liang Emmanuelle Souzeau Ian L McAllister Timothy Isaacs Janette Hall Stewart Lake David A Mackey Ian J Constable Jamie E Craig Terrie E Kitchner Zhenglin Yang Zhiguang Su Hongrong Luo Daniel Chen Hong Ouyang Ken Flagg Danni Lin Guanping Mao Henry Ferreyra Klaus Stark Claudia N von Strachwitz Armin Wolf Caroline Brandl Guenther Rudolph Matthias Olden Margaux A Morrison Denise J Morgan Matthew Schu Jeeyun Ahn Giuliana Silvestri Evangelia E Tsironi Kyu Hyung Park Lindsay A Farrer Anton Orlin Alexander Brucker Mingyao Li Christine A Curcio Saddek Mohand-Saïd José-Alain Sahel Isabelle Audo Mustapha Benchaboune Angela J Cree Christina A Rennie Srinivas V Goverdhan Michelle Grunin Shira Hagbi-Levi Peter Campochiaro Nicholas Katsanis Frank G Holz Frédéric Blond Hélène Blanché Jean-François Deleuze Robert P Igo Barbara Truitt Neal S Peachey Stacy M Meuer Chelsea E Myers Emily L Moore Ronald Klein Michael A Hauser Eric A Postel Monique D Courtenay Stephen G Schwartz Jaclyn L Kovach William K Scott Gerald Liew Ava G Tan Bamini Gopinath John C Merriam R Theodore Smith Jane C Khan Humma Shahid Anthony T Moore J Allie McGrath Reneé Laux Milam A Brantley Anita Agarwal Lebriz Ersoy Albert Caramoy Thomas Langmann Nicole T M Saksens Eiko K de Jong Carel B Hoyng Melinda S Cain Andrea J Richardson Tammy M Martin John Blangero Daniel E Weeks Bal Dhillon Cornelia M van Duijn Kimberly F Doheny Jane Romm Caroline C W Klaver Caroline Hayward Michael B Gorin Michael L Klein Paul N Baird Anneke I den Hollander Sascha Fauser John R W Yates Rando Allikmets Jie Jin Wang Debra A Schaumberg Barbara E K Klein Stephanie A Hagstrom Itay Chowers Andrew J Lotery Thierry Léveillard Kang Zhang Murray H Brilliant Alex W Hewitt Anand Swaroop Emily Y Chew Margaret A Pericak-Vance Margaret DeAngelis Dwight Stambolian Jonathan L Haines Sudha K Iyengar Bernhard H F Weber Gonçalo R Abecasis Iris M Heid

Nat Genet 2016 Feb 21;48(2):134-43. Epub 2015 Dec 21.

Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.3448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745342PMC
February 2016

Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration.

Ophthalmology 2015 Nov 6;122(11):2286-94. Epub 2015 Sep 6.

Department of Ophthalmology and Visual Sciences, McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. Electronic address:

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http://dx.doi.org/10.1016/j.ophtha.2015.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714866PMC
November 2015

Small Drusen and Age-Related Macular Degeneration: The Beaver Dam Eye Study.

J Clin Med 2015 Mar;4(3):424-40

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA.

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http://dx.doi.org/10.3390/jcm4030425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402933PMC
March 2015

Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure.

Invest Ophthalmol Vis Sci 2014 Dec 18;56(1):544-51. Epub 2014 Dec 18.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States.

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http://dx.doi.org/10.1167/iovs.14-15204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303040PMC
December 2014

Meta-analysis of genome-wide association studies in multiethnic Asians identifies two loci for age-related nuclear cataract.

Hum Mol Genet 2014 Nov 20;23(22):6119-28. Epub 2014 Jun 20.

Singapore Eye Research Institute, Singapore National Eye Center, Singapore 168751, Singapore, Department of Ophthalmology, Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore, Duke-National University of Singapore Graduate Medical School, Singapore 169857, Singapore,

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http://dx.doi.org/10.1093/hmg/ddu315DOI Listing
November 2014

Association between AVPR1A, DRD2, and ASPM and endophenotypes of communication disorders.

Psychiatr Genet 2014 Oct;24(5):191-200

Departments of aEpidemiology and Biostatistics bPsychological Sciences cPediatrics dGenetics eCenter for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1097/YPG.0000000000000045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141900PMC
October 2014

Cigarette smoking and the natural history of age-related macular degeneration: the Beaver Dam Eye Study.

Ophthalmology 2014 Oct 20;121(10):1949-55. Epub 2014 Jun 20.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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https://linkinghub.elsevier.com/retrieve/pii/S01616420140039
Publisher Site
http://dx.doi.org/10.1016/j.ophtha.2014.04.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177947PMC
October 2014

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.

PLoS Genet 2014 Aug 7;10(8):e1004517. Epub 2014 Aug 7.

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125087PMC
August 2014

Sunlight exposure, pigmentation, and incident age-related macular degeneration.

Invest Ophthalmol Vis Sci 2014 Aug 14;55(9):5855-61. Epub 2014 Aug 14.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
Publisher Site
http://dx.doi.org/10.1167/iovs.14-14602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165367PMC
August 2014

Misclassification can explain most apparent regression of age-related macular degeneration: results from multistate models with misclassification.

Invest Ophthalmol Vis Sci 2014 Mar 20;55(3):1780-6. Epub 2014 Mar 20.

Department of Biostatistics and Medical Informatics and Department of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://iovs.arvojournals.org/data/Journals/IOVS/933471/i1552
Web Search
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
Publisher Site
http://dx.doi.org/10.1167/iovs.13-12375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968926PMC
March 2014

Inhibition of EGF signaling protects the diabetic retina from insulin-induced vascular leakage.

Am J Pathol 2013 Sep 3;183(3):987-95. Epub 2013 Jul 3.

Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.ajpath.2013.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763764PMC
September 2013

Does losartan prevent progression of early diabetic nephropathy in American Indians with type 2 diabetes?

Diabetes 2013 Sep;62(9):3014-6

Divisions of Nephrology and Endocrinology, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.2337/db13-0748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749328PMC
September 2013

Association of smoking and other risk factors with Fuchs' endothelial corneal dystrophy severity and corneal thickness.

Invest Ophthalmol Vis Sci 2013 Aug 27;54(8):5829-35. Epub 2013 Aug 27.

Department of Ophthalmology and Visual Sciences, Case Western Reserve University and University Hospitals Eye Institute, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1167/iovs.13-11918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755540PMC
August 2013

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

Authors:
Ching-Yu Cheng Maria Schache M Kamran Ikram Terri L Young Jeremy A Guggenheim Veronique Vitart Stuart MacGregor Virginie J M Verhoeven Veluchamy A Barathi Jiemin Liao Pirro G Hysi Joan E Bailey-Wilson Beate St Pourcain John P Kemp George McMahon Nicholas J Timpson David M Evans Grant W Montgomery Aniket Mishra Ya Xing Wang Jie Jin Wang Elena Rochtchina Ozren Polasek Alan F Wright Najaf Amin Elisabeth M van Leeuwen James F Wilson Craig E Pennell Cornelia M van Duijn Paulus T V M de Jong Johannes R Vingerling Xin Zhou Peng Chen Ruoying Li Wan-Ting Tay Yingfeng Zheng Merwyn Chew Kathryn P Burdon Jamie E Craig Sudha K Iyengar Robert P Igo Jonathan H Lass Emily Y Chew Toomas Haller Evelin Mihailov Andres Metspalu Juho Wedenoja Claire L Simpson Robert Wojciechowski René Höhn Alireza Mirshahi Tanja Zeller Norbert Pfeiffer Karl J Lackner Thomas Bettecken Thomas Meitinger Konrad Oexle Mario Pirastu Laura Portas Abhishek Nag Katie M Williams Ekaterina Yonova-Doing Ronald Klein Barbara E Klein S Mohsen Hosseini Andrew D Paterson Kari-Matti Makela Terho Lehtimaki Mika Kahonen Olli Raitakari Nagahisa Yoshimura Fumihiko Matsuda Li Jia Chen Chi Pui Pang Shea Ping Yip Maurice K H Yap Akira Meguro Nobuhisa Mizuki Hidetoshi Inoko Paul J Foster Jing Hua Zhao Eranga Vithana E-Shyong Tai Qiao Fan Liang Xu Harry Campbell Brian Fleck Igor Rudan Tin Aung Albert Hofman André G Uitterlinden Goran Bencic Chiea-Chuen Khor Hannah Forward Olavi Pärssinen Paul Mitchell Fernando Rivadeneira Alex W Hewitt Cathy Williams Ben A Oostra Yik-Ying Teo Christopher J Hammond Dwight Stambolian David A Mackey Caroline C W Klaver Tien-Yin Wong Seang-Mei Saw Paul N Baird

Am J Hum Genet 2013 Aug;93(2):264-77

Department of Ophthalmology, National University of Singapore and National University Health System, Singapore 119228, Singapore; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore 117597, Singapore; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore 168751, Singapore; Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore 169857, Singapore.

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http://dx.doi.org/10.1016/j.ajhg.2013.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772747PMC
August 2013

The relationship of atherosclerosis to the 10-year cumulative incidence of age-related macular degeneration: the Beaver Dam studies.

Ophthalmology 2013 May 8;120(5):1012-9. Epub 2013 Feb 8.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726, USA.

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http://dx.doi.org/10.1016/j.ophtha.2012.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646961PMC
May 2013

The fibromyalgia family study: a genome-wide linkage scan study.

Arthritis Rheum 2013 Apr;65(4):1122-8

Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, Ohio 44106, USA.

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http://doi.wiley.com/10.1002/art.37842
Publisher Site
http://dx.doi.org/10.1002/art.37842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3618544PMC
April 2013

Seven new loci associated with age-related macular degeneration.

Authors:
Lars G Fritsche Wei Chen Matthew Schu Brian L Yaspan Yi Yu Gudmar Thorleifsson Donald J Zack Satoshi Arakawa Valentina Cipriani Stephan Ripke Robert P Igo Gabriëlle H S Buitendijk Xueling Sim Daniel E Weeks Robyn H Guymer Joanna E Merriam Peter J Francis Gregory Hannum Anita Agarwal Ana Maria Armbrecht Isabelle Audo Tin Aung Gaetano R Barile Mustapha Benchaboune Alan C Bird Paul N Bishop Kari E Branham Matthew Brooks Alexander J Brucker William H Cade Melinda S Cain Peter A Campochiaro Chi-Chao Chan Ching-Yu Cheng Emily Y Chew Kimberly A Chin Itay Chowers David G Clayton Radu Cojocaru Yvette P Conley Belinda K Cornes Mark J Daly Baljean Dhillon Albert O Edwards Evangelos Evangelou Jesen Fagerness Henry A Ferreyra James S Friedman Asbjorg Geirsdottir Ronnie J George Christian Gieger Neel Gupta Stephanie A Hagstrom Simon P Harding Christos Haritoglou John R Heckenlively Frank G Holz Guy Hughes John P A Ioannidis Tatsuro Ishibashi Peronne Joseph Gyungah Jun Yoichiro Kamatani Nicholas Katsanis Claudia N Keilhauer Jane C Khan Ivana K Kim Yutaka Kiyohara Barbara E K Klein Ronald Klein Jaclyn L Kovach Igor Kozak Clara J Lee Kristine E Lee Peter Lichtner Andrew J Lotery Thomas Meitinger Paul Mitchell Saddek Mohand-Saïd Anthony T Moore Denise J Morgan Margaux A Morrison Chelsea E Myers Adam C Naj Yusuke Nakamura Yukinori Okada Anton Orlin M Carolina Ortube Mohammad I Othman Chris Pappas Kyu Hyung Park Gayle J T Pauer Neal S Peachey Olivier Poch Rinki Ratna Priya Robyn Reynolds Andrea J Richardson Raymond Ripp Guenther Rudolph Euijung Ryu José-Alain Sahel Debra A Schaumberg Hendrik P N Scholl Stephen G Schwartz William K Scott Humma Shahid Haraldur Sigurdsson Giuliana Silvestri Theru A Sivakumaran R Theodore Smith Lucia Sobrin Eric H Souied Dwight E Stambolian Hreinn Stefansson Gwen M Sturgill-Short Atsushi Takahashi Nirubol Tosakulwong Barbara J Truitt Evangelia E Tsironi André G Uitterlinden Cornelia M van Duijn Lingam Vijaya Johannes R Vingerling Eranga N Vithana Andrew R Webster H-Erich Wichmann Thomas W Winkler Tien Y Wong Alan F Wright Diana Zelenika Ming Zhang Ling Zhao Kang Zhang Michael L Klein Gregory S Hageman G Mark Lathrop Kari Stefansson Rando Allikmets Paul N Baird Michael B Gorin Jie Jin Wang Caroline C W Klaver Johanna M Seddon Margaret A Pericak-Vance Sudha K Iyengar John R W Yates Anand Swaroop Bernhard H F Weber Michiaki Kubo Margaret M Deangelis Thierry Léveillard Unnur Thorsteinsdottir Jonathan L Haines Lindsay A Farrer Iris M Heid Gonçalo R Abecasis

Nat Genet 2013 Apr 3;45(4):433-9, 439e1-2. Epub 2013 Mar 3.

Institute of Human Genetics, University of Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1038/ng.2578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739472PMC
April 2013

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

Authors:
Virginie J M Verhoeven Pirro G Hysi Robert Wojciechowski Qiao Fan Jeremy A Guggenheim René Höhn Stuart MacGregor Alex W Hewitt Abhishek Nag Ching-Yu Cheng Ekaterina Yonova-Doing Xin Zhou M Kamran Ikram Gabriëlle H S Buitendijk George McMahon John P Kemp Beate St Pourcain Claire L Simpson Kari-Matti Mäkelä Terho Lehtimäki Mika Kähönen Andrew D Paterson S Mohsen Hosseini Hoi Suen Wong Liang Xu Jost B Jonas Olavi Pärssinen Juho Wedenoja Shea Ping Yip Daniel W H Ho Chi Pui Pang Li Jia Chen Kathryn P Burdon Jamie E Craig Barbara E K Klein Ronald Klein Toomas Haller Andres Metspalu Chiea-Chuen Khor E-Shyong Tai Tin Aung Eranga Vithana Wan-Ting Tay Veluchamy A Barathi Peng Chen Ruoying Li Jiemin Liao Yingfeng Zheng Rick T Ong Angela Döring David M Evans Nicholas J Timpson Annemieke J M H Verkerk Thomas Meitinger Olli Raitakari Felicia Hawthorne Tim D Spector Lennart C Karssen Mario Pirastu Federico Murgia Wei Ang Aniket Mishra Grant W Montgomery Craig E Pennell Phillippa M Cumberland Ioana Cotlarciuc Paul Mitchell Jie Jin Wang Maria Schache Sarayut Janmahasatian Sarayut Janmahasathian Robert P Igo Jonathan H Lass Emily Chew Sudha K Iyengar Theo G M F Gorgels Igor Rudan Caroline Hayward Alan F Wright Ozren Polasek Zoran Vatavuk James F Wilson Brian Fleck Tanja Zeller Alireza Mirshahi Christian Müller André G Uitterlinden Fernando Rivadeneira Johannes R Vingerling Albert Hofman Ben A Oostra Najaf Amin Arthur A B Bergen Yik-Ying Teo Jugnoo S Rahi Veronique Vitart Cathy Williams Paul N Baird Tien-Yin Wong Konrad Oexle Norbert Pfeiffer David A Mackey Terri L Young Cornelia M van Duijn Seang-Mei Saw Joan E Bailey-Wilson Dwight Stambolian Caroline C Klaver Christopher J Hammond

Nat Genet 2013 Mar 10;45(3):314-8. Epub 2013 Feb 10.

Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740568PMC
March 2013

Risk alleles in CFH and ARMS2 and the long-term natural history of age-related macular degeneration: the Beaver Dam Eye Study.

JAMA Ophthalmol 2013 Mar;131(3):383-92

Departments of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53726, USA.

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http://dx.doi.org/10.1001/jamaophthalmol.2013.713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602927PMC
March 2013

Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma.

Nat Genet 2012 Oct 26;44(10):1142-1146. Epub 2012 Aug 26.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

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http://dx.doi.org/10.1038/ng.2390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333205PMC
October 2012

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium.

Authors:
Virginie J M Verhoeven Pirro G Hysi Seang-Mei Saw Veronique Vitart Alireza Mirshahi Jeremy A Guggenheim Mary Frances Cotch Kenji Yamashiro Paul N Baird David A Mackey Robert Wojciechowski M Kamran Ikram Alex W Hewitt Priya Duggal Sarayut Janmahasatian Chiea-Chuen Khor Qiao Fan Xin Zhou Terri L Young E-Shyong Tai Liang-Kee Goh Yi-Ju Li Tin Aung Eranga Vithana Yik-Ying Teo Wanting Tay Xueling Sim Igor Rudan Caroline Hayward Alan F Wright Ozren Polasek Harry Campbell James F Wilson Brian W Fleck Isao Nakata Nagahisa Yoshimura Ryo Yamada Fumihiko Matsuda Kyoko Ohno-Matsui Abhishek Nag George McMahon Beate St Pourcain Yi Lu Jugnoo S Rahi Phillippa M Cumberland Shomi Bhattacharya Claire L Simpson Larry D Atwood Xiaohui Li Leslie J Raffel Federico Murgia Laura Portas Dominiek D G Despriet Leonieke M E van Koolwijk Christian Wolfram Karl J Lackner Anke Tönjes Reedik Mägi Terho Lehtimäki Mika Kähönen Tõnu Esko Andres Metspalu Taina Rantanen Olavi Pärssinen Barbara E Klein Thomas Meitinger Timothy D Spector Ben A Oostra Albert V Smith Paulus T V M de Jong Albert Hofman Najaf Amin Lennart C Karssen Fernando Rivadeneira Johannes R Vingerling Guðný Eiríksdóttir Vilmundur Gudnason Angela Döring Thomas Bettecken André G Uitterlinden Cathy Williams Tanja Zeller Raphaële Castagné Konrad Oexle Cornelia M van Duijn Sudha K Iyengar Paul Mitchell Jie Jin Wang René Höhn Norbert Pfeiffer Joan E Bailey-Wilson Dwight Stambolian Tien-Yin Wong Christopher J Hammond Caroline C W Klaver

Hum Genet 2012 Sep 5;131(9):1467-80. Epub 2012 Jun 5.

Department of Ophthalmology, Erasmus Medical Center, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00439-012-1176-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418496PMC
September 2012

Speech-Sound Disorders and Attention-Deficit/Hyperactivity Disorder Symptoms.

Top Lang Disord 2012 Sep;32(3):247-263

Departments of Psychological Sciences (Drs Lewis and Short and Mss Freebairn and Tag), Epidemiology and Biostatistics (Drs Iyengar and Stein and Ms Avrich), and Pediatrics (Dr Taylor), Case Western Reserve University, Cleveland, Ohio.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868495PMC
September 2012

The relationship of cataract and cataract extraction to age-related macular degeneration: the Beaver Dam Eye Study.

Ophthalmology 2012 Aug 11;119(8):1628-33. Epub 2012 May 11.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1016/j.ophtha.2012.01.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411928PMC
August 2012

Variation in the lysyl oxidase (LOX) gene is associated with keratoconus in family-based and case-control studies.

Invest Ophthalmol Vis Sci 2012 Jun 28;53(7):4152-7. Epub 2012 Jun 28.

Regenerative Medicine Institute, Ophthalmology Research, Department of Surgery, Division of Surgical Research, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

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http://dx.doi.org/10.1167/iovs.11-9268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760233PMC
June 2012

Heritability estimation for speech-sound traits with developmental trajectories.

Behav Genet 2011 Mar 10;41(2):184-91. Epub 2010 Jul 10.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://link.springer.com/10.1007/s10519-010-9378-5
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http://dx.doi.org/10.1007/s10519-010-9378-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066568PMC
March 2011

Subtyping Children With Speech Sound Disorders by Endophenotypes.

Top Lang Disord 2011 ;31(2):112-127

Department of Psychological Sciences, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1097/TLD.0b013e318217b5ddDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404745PMC
January 2011

Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.

Clin J Am Soc Nephrol 2010 Jun 18;5(6):1072-8. Epub 2010 Mar 18.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.2215/CJN.06550909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879299PMC
June 2010

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

Proc Natl Acad Sci U S A 2010 Apr 12;107(16):7401-6. Epub 2010 Apr 12.

Center for Statistical Genetics, Biostatistics, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1073/pnas.0912702107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867722PMC
April 2010

Studying genetic determinants of natural variation in human gene expression using Bayesian ANOVA.

BMC Proc 2007 18;1 Suppl 1:S115. Epub 2007 Dec 18.

Department of Epidemiology and Biostatistics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367590PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s115DOI Listing
December 2009

Examining the relative influence of familial, genetic, and environmental covariate information in flexible risk models.

Proc Natl Acad Sci U S A 2009 May 6;106(20):8128-33. Epub 2009 May 6.

Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0902906106
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http://dx.doi.org/10.1073/pnas.0902906106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677979PMC
May 2009

CKD increases the risk of age-related macular degeneration.

J Am Soc Nephrol 2008 Apr 23;19(4):806-11. Epub 2008 Jan 23.

Centre for Vision Research, Department of Ophthalmology, University of Sydney, Westmead Hospital, Hawkesbury Road, Westmead, NSW Australia.

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http://dx.doi.org/10.1681/ASN.2007080844DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2390960PMC
April 2008

The epidemiology of retinal reticular drusen.

Am J Ophthalmol 2008 Feb 28;145(2):317-326. Epub 2007 Nov 28.

Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, 610 North Walnut Street, Madison, WI 53726, USA.

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http://dx.doi.org/10.1016/j.ajo.2007.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2258433PMC
February 2008

The genetic basis of complex traits: rare variants or "common gene, common disease"?

Methods Mol Biol 2007 ;376:71-84

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1007/978-1-59745-389-9_6DOI Listing
December 2007

Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes.

Hum Mol Genet 2007 Sep 25;16(17):2135-48. Epub 2007 Jun 25.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1093/hmg/ddm164DOI Listing
September 2007

Familial clustering of chronic kidney disease.

Semin Dial 2007 May-Jun;20(3):229-36

Department of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. 27157-1053

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http://dx.doi.org/10.1111/j.1525-139X.2007.00282.xDOI Listing
July 2007

Genetics of pigment changes and geographic atrophy.

Invest Ophthalmol Vis Sci 2007 Jul;48(7):3005-13

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio 44106-7281, USA.

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http://dx.doi.org/10.1167/iovs.06-1325DOI Listing
July 2007

Speech and language skills of parents of children with speech sound disorders.

Am J Speech Lang Pathol 2007 May;16(2):108-18

Behavioral Pediatrics and Psychology 6038, Rainbow Babies and Children's Hospital, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106-6038, USA.

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http://dx.doi.org/10.1044/1058-0360(2007/015)DOI Listing
May 2007

The application of the HapMap to diabetic nephropathy and other causes of chronic renal failure.

Semin Nephrol 2007 Mar;27(2):223-36

Department of Epidemiology and Biostatistics, Case Western Reserve University, 2103 Cornell Road, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1016/j.semnephrol.2007.01.003DOI Listing
March 2007