Dr. Subramanian Krishnan, PhD - Children's Hospital Los Angeles

Dr. Subramanian Krishnan

PhD

Children's Hospital Los Angeles

Los Angeles, CA | United States

Additional Specialties: Microbial pathogenesis, drug discovery, regulatory affairs

ORCID logohttps://orcid.org/0000-0001-5780-7452


Top Author

Dr. Subramanian Krishnan, PhD - Children's Hospital Los Angeles

Dr. Subramanian Krishnan

PhD

Introduction

PhD in Biotechnology • >8 years of research experience • Certified in drug development, humans subjects (HS) research, Good Clinical Practice (GCP), and HIPAA • Expert in Clinical and Scientific Regulatory Affairs.

Primary Affiliation: Children's Hospital Los Angeles - Los Angeles, CA , United States

Additional Specialties:


View Dr. Subramanian Krishnan’s Resume / CV

Education

Mar 2009
Anna University, India
PhD

Publications

19Publications

198Reads

605Profile Views

109PubMed Central Citations

CoYoT1 Clinic: Home Telemedicine Increases Young Adult Engagement in Diabetes Care.

Diabetes Technol Ther 2018 05 19;20(5):370-379. Epub 2018 Apr 19.

6 Department of Pediatrics, Division of Endocrinology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California , Los Angeles, California.

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http://dx.doi.org/10.1089/dia.2017.0450DOI Listing
May 2018
10 Reads
2.110 Impact Factor

Porous orbital implant after enucleation in retinoblastoma patients: indications and complications.

Orbit 2018 Feb 20:1-6. Epub 2018 Feb 20.

a USC Roski Eye Institute , Keck School of Medicine of the University of Southern California , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/01676830.2018.1440605DOI Listing
February 2018
7 Reads

Potential of Aqueous Humor as a Surrogate Tumor Biopsy for Retinoblastoma.

JAMA Ophthalmol 2017 11;135(11):1221-1230

Department of Biological Sciences, USC Dornsife College of Letters, Arts, and Sciences, University of Southern California, Los Angeles.

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http://dx.doi.org/10.1001/jamaophthalmol.2017.4097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710399PMC
November 2017
24 Reads
4 Citations

Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis.

Virulence 2015 25;6(8):777-86. Epub 2015 Sep 25.

a Division of Infectious Diseases and Department of Pediatrics; Children's Hospital Los Angeles , CA USA.

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http://dx.doi.org/10.1080/21505594.2015.1091914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826105PMC
October 2016
16 Reads
2 Citations
4.220 Impact Factor

Escherichia coli K1 Modulates Peroxisome Proliferator-Activated Receptor γ and Glucose Transporter 1 at the Blood-Brain Barrier in Neonatal Meningitis.

J Infect Dis 2016 10 24;214(7):1092-104. Epub 2016 Jul 24.

Division of Infectious Diseases, Department of Pediatrics Department of Surgery, Children's Hospital Los Angeles Keck School of Medicine, University of Southern California, Los Angeles.

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http://dx.doi.org/10.1093/infdis/jiw306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021232PMC
October 2016
11 Reads
6.000 Impact Factor

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

J Biol Chem 2014 Nov 17;289(45):30937-49. Epub 2014 Sep 17.

From the Division of Infectious Diseases and the Department of Pediatrics and the Department of Surgery, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California 90027,

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http://dx.doi.org/10.1074/jbc.M114.599407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223301PMC
November 2014
11 Reads
7 Citations
4.573 Impact Factor

Identification of minimum carbohydrate moiety in N-glycosylation sites of brain endothelial cell glycoprotein 96 for interaction with Escherichia coli K1 outer membrane protein A.

Microbes Infect 2014 Jul 13;16(7):540-52. Epub 2014 Jun 13.

Division of Infectious Diseases and Department of Pediatrics, Children's Hospital Los Angeles, 4650 Sunset Blvd., Los Angeles, CA 90027, USA; Department of Surgery, Children's Hospital Los Angeles and University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2014.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123687PMC
July 2014
5 Reads
5 Citations
2.861 Impact Factor

Escherichia coli K1 induces pterin production for enhanced expression of Fcγ receptor I to invade RAW 264.7 macrophages.

Microbes Infect 2014 Feb 23;16(2):134-41. Epub 2013 Oct 23.

Division of Infectious Diseases, Department of Pediatrics, Children's Hospital Los Angeles, 4650 Sunset Blvd., Los Angeles, CA 90027, USA; Department of Surgery, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd., Los Angeles, CA 90027, USA. Electronic address:

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http://dx.doi.org/10.1016/j.micinf.2013.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946618PMC
February 2014
11 Reads
2 Citations
2.861 Impact Factor

Attenuation of biopterin synthesis prevents Escherichia coli K1 invasion of brain endothelial cells and the development of meningitis in newborn mice.

J Infect Dis 2013 Jan 24;207(1):61-71. Epub 2012 Oct 24.

Division of Infectious Diseases, Department of Pediatrics, Children’s Hospital Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1093/infdis/jis656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523800PMC
January 2013
7 Reads
4 Citations
6.000 Impact Factor

Regulation of Toll-like receptor 2 interaction with Ecgp96 controls Escherichia coli K1 invasion of brain endothelial cells.

Cell Microbiol 2013 Jan 4;15(1):63-81. Epub 2012 Oct 4.

Division of Infectious Diseases, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.

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http://doi.wiley.com/10.1111/cmi.12026
Publisher Site
http://dx.doi.org/10.1111/cmi.12026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524395PMC
January 2013
14 Reads
8 Citations
4.920 Impact Factor

IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells.

Cell Microbiol 2012 Sep 24;14(9):1415-33. Epub 2012 May 24.

Division of Infectious Diseases, Department of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, University of Southern California School of Medicine, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1111/j.1462-5822.2012.01805.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410974PMC
September 2012
7 Reads
18 Citations
4.920 Impact Factor

Outer membrane protein A and OprF: versatile roles in Gram-negative bacterial infections.

FEBS J 2012 Mar 10;279(6):919-31. Epub 2012 Feb 10.

Division of Infectious Diseases, Department of Pediatrics, The Saban Research Institute, Children's Hospital Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08482.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338869PMC
March 2012
5 Reads
25 Citations
4.001 Impact Factor

Deciphering the roles of outer membrane protein A extracellular loops in the pathogenesis of Escherichia coli K1 meningitis.

J Biol Chem 2011 Jan 11;286(3):2183-93. Epub 2010 Nov 11.

Division of Infectious Diseases, Department of Pediatrics, Childrens Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1074/jbc.M110.178236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023514PMC
January 2011
13 Reads
15 Citations
4.573 Impact Factor

Outer membrane proteins of wild-type and intimin-deficient enteropathogenic Escherichia coli induce Hep-2 cell death through intrinsic and extrinsic pathways of apoptosis.

Int J Med Microbiol 2009 Feb 3;299(2):121-32. Epub 2008 Sep 3.

Centre for Biotechnology, Anna University, Chennai, India.

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http://dx.doi.org/10.1016/j.ijmm.2008.07.005DOI Listing
February 2009
11 Reads
2 Citations
3.614 Impact Factor

LamB-mediated adherence of enteropathogenic Escherichia coli to HEp-2 cells.

J Appl Microbiol 2008 Sep 4;105(3):715-22. Epub 2008 Apr 4.

Centre for Biotechnology, Anna University, Chennai, India.

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http://dx.doi.org/10.1111/j.1365-2672.2008.03800.xDOI Listing
September 2008
5 Reads
3 Citations
2.480 Impact Factor

Top co-authors

Nemani V Prasadarao
Nemani V Prasadarao

Children's Hospital Los Angeles

12
Muthusamy V Shanmuganathan
Muthusamy V Shanmuganathan

National Institute of Nutrition

3
Alexander C Chang
Alexander C Chang

Children's Hospital Los Angeles

3
Jesse L Berry
Jesse L Berry

University of Southern California

3
Jonathan W Kim
Jonathan W Kim

The Vision Center at Children's Hospital Los Angeles

3
Brian M Stoltz
Brian M Stoltz

The Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering

2
Emily Zolfaghari
Emily Zolfaghari

Keck School of Medicine

2
Xiaowei Fu
Xiaowei Fu

State Key Laboratory for Biology of Plant Diseases and Insect Pests

2
Krishnan Subramanian
Krishnan Subramanian

Anna University

2
Jacqueline Hodges
Jacqueline Hodges

a Division of Infectious Diseases and Department of Pediatrics; Children's Hospital Los Angeles

2