Publications by authors named "Subramaniam Ganesh"

75Publications

Trehalose Ameliorates Seizure Susceptibility in Lafora Disease Mouse Models by Suppressing Neuroinflammation and Endoplasmic Reticulum Stress.

Mol Neurobiol 2020 Oct 22. Epub 2020 Oct 22.

Department of Biological Sciences & Bioengineering, Indian Institute of Technology Kanpur, Kanpur, 208016, India.

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October 2020

Dendritic spine abnormalities correlate with behavioral and cognitive deficits in mouse models of Lafora disease.

J Comp Neurol 2020 Aug 12. Epub 2020 Aug 12.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, India.

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August 2020

Glycogen: the missing link in neuronal autophagy?

Autophagy 2020 11 2;16(11):2102-2104. Epub 2020 Aug 2.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur , Kanpur, India.

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November 2020

Perinuclear mitochondrial clustering, increased ROS levels, and HIF1 are required for the activation of HSF1 by heat stress.

J Cell Sci 2020 Jul 9;133(13). Epub 2020 Jul 9.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India

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July 2020

Extending Arms of Insulin Resistance from Diabetes to Alzheimer's Disease: Identification of Potential Therapeutic Targets.

CNS Neurol Disord Drug Targets 2019 ;18(3):172-184

Department of Biochemistry, Basic Medical Science Block II, Sector 25, Panjab University, Chandigarh 160014, India.

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June 2020

New discoveries in progressive myoclonus epilepsies: a clinical outlook.

Expert Rev Neurother 2018 08 9;18(8):649-667. Epub 2018 Aug 9.

a Department of Biological Sciences and Bioengineering , Indian Institute of Technology , Kanpur , India.

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August 2018

Lafora disease: from genotype to phenotype.

J Genet 2018 Jul;97(3):611-624

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208 016, India.

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July 2018

Corrigendum to "FoxO3a-mediated autophagy is down-regulated in the laforin deficient mice, an animal model for Lafora progressive myoclonus epilepsy" [Biochem. Biophys. Res. Commun. 474 (2) (2016) 321-327].

Biochem Biophys Res Commun 2018 09 17;503(2):1175-1176. Epub 2018 Jul 17.

Department of Biological Sciences & Bioengineering, Indian Institute of Technology, Kanpur 208016, India. Electronic address:

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September 2018

Sex-biased transgenerational effect of maternal stress on neurodevelopment and cognitive functions.

J Genet 2018 Jun;97(2):581-583

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208 016, India.

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June 2018

Evidence for Compromised Insulin Signaling and Neuronal Vulnerability in Experimental Model of Sporadic Alzheimer's Disease.

Mol Neurobiol 2018 Dec 3;55(12):8916-8935. Epub 2018 Apr 3.

Department of Biochemistry, Basic Medical Science Block II, Sector 25, Panjab University, Chandigarh, 160014, India.

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December 2018

Suppression of leptin signaling reduces polyglucosan inclusions and seizure susceptibility in a mouse model for Lafora disease.

Hum Mol Genet 2017 12;26(24):4778-4785

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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December 2017

Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models.

Neurobiol Dis 2017 Apr 4;100:39-51. Epub 2017 Jan 4.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India. Electronic address:

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April 2017

Loss of malin, but not laforin, results in compromised autophagic flux and proteasomal dysfunction in cells exposed to heat shock.

Cell Stress Chaperones 2017 03 14;22(2):307-315. Epub 2016 Dec 14.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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March 2017

Autism genes: the continuum that connects us all.

J Genet 2016 09;95(3):481-3

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208 016, India.

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September 2016

Human satellite-III non-coding RNAs modulate heat-shock-induced transcriptional repression.

J Cell Sci 2016 10 15;129(19):3541-3552. Epub 2016 Aug 15.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India

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October 2016

FoxO3a-mediated autophagy is down-regulated in the laforin deficient mice, an animal model for Lafora progressive myoclonus epilepsy.

Biochem Biophys Res Commun 2016 05 21;474(2):321-327. Epub 2016 Apr 21.

Department of Biological Sciences & Bioengineering, Indian Institute of Technology, Kanpur 208016, India. Electronic address:

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May 2016

Emerging nexus between RAB GTPases, autophagy and neurodegeneration.

Autophagy 2016 05 17;12(5):900-4. Epub 2016 Mar 17.

a Department of Biological Sciences & Bioengineering , Indian Institute of Technology , Kanpur , India.

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May 2016

Heat shock modulates the subcellular localization, stability, and activity of HIPK2.

Biochem Biophys Res Commun 2016 Apr 10;472(4):580-4. Epub 2016 Mar 10.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, India. Electronic address:

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April 2016

Lafora disease proteins laforin and malin negatively regulate the HIPK2-p53 cell death pathway.

Biochem Biophys Res Commun 2015 Aug 21;464(1):106-11. Epub 2015 Jun 21.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India; Center of Excellence for Chemical Biology, Indian Institute of Technology, Kanpur, India. Electronic address:

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August 2015

Association of the GRM4 gene variants with juvenile myoclonic epilepsy in an Indian population.

J Genet 2014 Apr;93(1):193-7

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208 016, India.

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April 2014

Decreased O-linked GlcNAcylation protects from cytotoxicity mediated by huntingtin exon1 protein fragment.

J Biol Chem 2014 May 19;289(19):13543-53. Epub 2014 Mar 19.

From the Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016 and.

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May 2014

Activation of serum/glucocorticoid-induced kinase 1 (SGK1) underlies increased glycogen levels, mTOR activation, and autophagy defects in Lafora disease.

Mol Biol Cell 2013 Dec 16;24(24):3776-86. Epub 2013 Oct 16.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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December 2013

The SCN1A gene variants and epileptic encephalopathies.

J Hum Genet 2013 Sep 25;58(9):573-80. Epub 2013 Jul 25.

1] Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India [2] Department of Biochemistry, G.R.Medical College, Gwalior, India.

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September 2013

Lafora disease E3 ubiquitin ligase malin is recruited to the processing bodies and regulates the microRNA-mediated gene silencing process via the decapping enzyme Dcp1a.

RNA Biol 2012 Dec 6;9(12):1440-9. Epub 2012 Nov 6.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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December 2012

Haplotypic association of ADAM33 (T+1, S+1 and V - 3) gene variants in genetic susceptibility to asthma in Indian population.

Ann Hum Biol 2012 Nov-Dec;39(6):479-83. Epub 2012 Sep 18.

Department of Pediatrics, King George's Medical University, Lucknow, U.P., India.

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April 2013

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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April 2012

Novel chemosensor for the visual detection of copper(II) in aqueous solution at the ppm level.

Inorg Chem 2012 Aug 6;51(16):8664-6. Epub 2012 Aug 6.

Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, India.

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August 2012

Phenotype variations in Lafora progressive myoclonus epilepsy: possible involvement of genetic modifiers?

J Hum Genet 2012 May 29;57(5):283-5. Epub 2012 Mar 29.

Department of Human Biology, International Medical University, No. 126 Jalan Jalil Perkasa 19, Bukit Jalil, Kuala Lumpur, Malaysia.

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May 2012

Autophagy defects in Lafora disease: cause or consequence?

Autophagy 2012 Feb 1;8(2):289-90. Epub 2012 Feb 1.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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February 2012

The laforin-malin complex negatively regulates glycogen synthesis by modulating cellular glucose uptake via glucose transporters.

Mol Cell Biol 2012 Feb 28;32(3):652-63. Epub 2011 Nov 28.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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February 2012

Identification and characterization of novel splice variants of the human EPM2A gene mutated in Lafora progressive myoclonus epilepsy.

Genomics 2012 Jan 19;99(1):36-43. Epub 2011 Oct 19.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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January 2012

Dysfunctions in endosomal-lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease.

Hum Mol Genet 2012 Jan 30;21(1):175-84. Epub 2011 Sep 30.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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January 2012

Association of ADAM33 gene polymorphisms with adult-onset asthma and its severity in an Indian adult population.

J Genet 2011 Aug;90(2):265-73

Department of Pediatrics, Chhtrapati Shahuji Maharaj Medical University, Chowk, Lucknow 226 003, India.

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August 2011

Increased glucose concentration results in reduced proteasomal activity and the formation of glycogen positive aggresomal structures.

FEBS J 2011 Oct 8;278(19):3688-98. Epub 2011 Sep 8.

Department of Biological Sciences and Bioengineering, India Institute of Technology, Kanpur, India.

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October 2011

Malin and laforin are essential components of a protein complex that protects cells from thermal stress.

J Cell Sci 2011 Jul 7;124(Pt 13):2277-86. Epub 2011 Jun 7.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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July 2011

Proline repeats, in cis- and trans-positions, confer protection against the toxicity of misfolded proteins in a mammalian cellular model.

Neurosci Res 2011 Aug 17;70(4):435-41. Epub 2011 May 17.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kalyanpur, Kanpur, UP 208016, India.

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August 2011

Association of ADAM33 gene polymorphisms with asthma in Indian children.

J Hum Genet 2011 Mar 23;56(3):188-95. Epub 2010 Dec 23.

Department of Pediatrics, Chhatrapati Shahuji Maharaj Medical University, Lucknow, India.

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March 2011

Laforin in autophagy: a possible link between carbohydrate and protein in Lafora disease?

Autophagy 2010 Nov;6(8):1229-31

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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November 2010

Protein quality control mechanisms and neurodegenerative disorders: Checks, balances and deadlocks.

Neurosci Res 2010 Nov 11;68(3):159-66. Epub 2010 Aug 11.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kalyanpur, Kanpur 208016, UP, India.

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November 2010

Juvenile myoclonic epilepsy: EFHC1 at the cross-roads?

Ann Neurosci 2010 Apr;17(2):57-9

Deptt of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, INDIA E-mail : Tel: 91-512-259 4040 -512-259-4010.

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April 2010

Hyperphosphorylation and aggregation of Tau in laforin-deficient mice, an animal model for Lafora disease.

J Biol Chem 2009 Aug 19;284(34):22657-63. Epub 2009 Jun 19.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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August 2009

Lafora progressive myoclonus epilepsy: a meta-analysis of reported mutations in the first decade following the discovery of the EPM2A and NHLRC1 genes.

Hum Mutat 2009 May;30(5):715-23

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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May 2009

Satellite III non-coding RNAs show distinct and stress-specific patterns of induction.

Biochem Biophys Res Commun 2009 Apr 1;382(1):102-7. Epub 2009 Mar 1.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208 016, India.

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April 2009

Spatial positions of homopolymeric repeats in the human proteome and their effect on cellular toxicity.

Biochem Biophys Res Commun 2009 Mar 23;380(2):382-6. Epub 2009 Jan 23.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kalyanpur, Kanpur 208016, India.

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March 2009

Mannosylated self-assembled structures for molecular confinement and gene delivery applications.

Biochem Biophys Res Commun 2009 Jan 24;378(3):503-6. Epub 2008 Nov 24.

Department of Chemistry, Indian Institute of Technology-Kanpur, Kanpur 208016 (UP), India.

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January 2009

Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy.

Hum Mol Genet 2008 Oct 10;17(19):3010-20. Epub 2008 Jul 10.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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October 2008

Non-coding RNAs in polyglutamine disorders: friend or foe?

J Biosci 2008 Jun;33(2):303-6

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208 016, India.

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June 2008

Tandem repeats in human disorders: mechanisms and evolution.

Front Biosci 2008 May 1;13:4467-84. Epub 2008 May 1.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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May 2008

Identification and comparative analysis of novel alternatively spliced transcripts of RhoGEF domain encoding gene in C. elegans and C. briggsae.

Bioinformation 2007 Sep 11;2(2):43-9. Epub 2007 Sep 11.

Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, India.

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September 2007

Inflammatory system gene polymorphism and the risk of stroke: a case-control study in an Indian population.

Brain Res Bull 2008 Jan 24;75(1):158-65. Epub 2007 Sep 24.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.

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January 2008

Association between inflammatory gene polymorphisms and coronary artery disease in an Indian population.

J Thromb Thrombolysis 2009 Jan 23;27(1):88-94. Epub 2007 Dec 23.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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January 2009

Protein bioinformatics and mixtures of bivariate von Mises distributions for angular data.

Biometrics 2007 Jun;63(2):505-12

School of Mathematics, University of Leeds, Leeds, LS2 9JT, UK.

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June 2007

Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment.

Hum Mol Genet 2007 Apr 2;16(7):753-62. Epub 2007 Mar 2.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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April 2007

Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis.

J Hum Genet 2007 14;52(3):205-219. Epub 2006 Dec 14.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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April 2007

Genomic and evolutionary insights into genes encoding proteins with single amino acid repeats.

Mol Biol Evol 2006 Jul 17;23(7):1357-69. Epub 2006 Apr 17.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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July 2006

Neuronal survival in epilepsy: to die or not to die?

J Biosci 2005 Dec;30(5):561-6

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208 016, India.

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December 2005

Recent advances in the molecular basis of Lafora's progressive myoclonus epilepsy.

J Hum Genet 2006 26;51(1):1-8. Epub 2005 Nov 26.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, 208016, India.

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March 2006

The carbohydrate-binding domain of Lafora disease protein targets Lafora polyglucosan bodies.

Biochem Biophys Res Commun 2004 Jan;313(4):1101-9

Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.

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January 2004

Evolutionarily conserved, DMRT1, encodes alternatively spliced transcripts and shows dimorphic expression during gonadal differentiation in the lizard, Calotes versicolor.

Gene Expr Patterns 2002 Nov;2(1-2):51-60

Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, Varanasi, 221005, India.

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November 2002

Alternative splicing modulates subcellular localization of laforin.

Biochem Biophys Res Commun 2002 Mar;291(5):1134-7

Laboratory for Neurogenetics, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan.

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March 2002