Subha Madhavan

Subha Madhavan

UNVERIFIED PROFILE

Are you Subha Madhavan?   Register this Author

Register author
Subha Madhavan

Subha Madhavan

Publications by authors named "Subha Madhavan"

Are you Subha Madhavan?   Register this Author

60Publications

1076Reads

20Profile Views

Safety and efficacy of immune checkpoint inhibitors (ICIs) in cancer patients with HIV, hepatitis B, or hepatitis C viral infection.

J Immunother Cancer 2019 Dec 17;7(1):353. Epub 2019 Dec 17.

Lombardi Comprehensive Cancer Center MedStar Georgetown University Hospital, 3800 Reservoir Rd. N.W., LCCC Bldg, 2nd FL, Pod B P413, Washington, DC, 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40425-019-0771-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6918622PMC
December 2019

A case for expert curation: an overview of cancer curation in the Clinical Genome Resource (ClinGen).

Cold Spring Harb Mol Case Stud 2019 Oct 23;5(5). Epub 2019 Oct 23.

Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/mcs.a004739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824250PMC
October 2019

miR-21 Expression Determines the Early Vaccine Immunity Induced by Immunization.

Front Immunol 2019 24;10:2273. Epub 2019 Sep 24.

Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.02273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769120PMC
September 2019

SNP2SIM: a modular workflow for standardizing molecular simulation and functional analysis of protein variants.

BMC Bioinformatics 2019 Apr 3;20(1):171. Epub 2019 Apr 3.

Innovation Center for Biomedical Informatics, Georgetown University Medical Center, 2115 Wisconsin Avenue, NW, Suite 110, Washington, D.C., 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-019-2774-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448223PMC
April 2019

Curation of the Pancreatic Ductal Adenocarcinoma Subset of the Cancer Genome Atlas Is Essential for Accurate Conclusions about Survival-Related Molecular Mechanisms.

Clin Cancer Res 2018 08 8;24(16):3813-3819. Epub 2018 May 8.

Georgetown-Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University Medical Center, Washington, DC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-18-0290DOI Listing
August 2018

The REMBRANDT study, a large collection of genomic data from brain cancer patients.

Sci Data 2018 08 14;5:180158. Epub 2018 Aug 14.

Innovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington DC 20007, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/sdata2018158
Publisher Site
http://dx.doi.org/10.1038/sdata.2018.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6091243PMC
August 2018

viGEN: An Open Source Pipeline for the Detection and Quantification of Viral RNA in Human Tumors.

Front Microbiol 2018 5;9:1172. Epub 2018 Jun 5.

Innovation Center for Biomedical Informatics, Georgetown University, Washington, DC, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2018.01172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996193PMC
June 2018

A Computational Approach for Prioritizing Selection of Therapies Targeting Drug Resistant Variation in Anaplastic Lymphoma Kinase.

AMIA Jt Summits Transl Sci Proc 2018 18;2017:160-167. Epub 2018 May 18.

Innovation Center for Biomedical Informatics, Georgetown University Medical Center,Washington, DC, United States of America.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961773PMC
May 2018

Art and Challenges of Precision Medicine: Interpreting and Integrating Genomic Data Into Clinical Practice.

Am Soc Clin Oncol Educ Book 2018 May;38:546-553

From the Innovation Center for Biomedical Informatics, Georgetown University, Washington, DC; Swedish Cancer Institute, Seattle, WA; The Ohio State University, Columbus, OH.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/EDBK_200759DOI Listing
May 2018

POPSTR: Inference of Admixed Population Structure Based on Single-Nucleotide Polymorphisms and Copy Number Variations.

J Comput Biol 2018 04 2;25(4):417-429. Epub 2018 Jan 2.

2 Innovation Center for Biomedical Informatics, Georgetown University , Washington, District of Columbia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/cmb.2017.0127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915226PMC
April 2018

eGARD: Extracting associations between genomic anomalies and drug responses from text.

PLoS One 2017 20;12(12):e0189663. Epub 2017 Dec 20.

Department of Computer and Information Science, University of Delaware, Newark, Delaware, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0189663PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738129PMC
January 2018

CINdex: A Bioconductor Package for Analysis of Chromosome Instability in DNA Copy Number Data.

Cancer Inform 2017 13;16:1176935117746637. Epub 2017 Dec 13.

Innovation Center for Biomedical Informatics, Georgetown University, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1176935117746637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761903PMC
December 2017

EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer.

Oncotarget 2017 Nov 30;8(57):96865-96884. Epub 2017 May 30.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.18292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722529PMC
November 2017

Ly6E/K Signaling to TGFβ Promotes Breast Cancer Progression, Immune Escape, and Drug Resistance.

Cancer Res 2016 06 11;76(11):3376-86. Epub 2016 Apr 11.

Department of Oncology, Georgetown University Medical Center, Washington, DC. Innovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington, DC.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-15-2654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910623PMC
June 2016

SNP2Structure: A Public and Versatile Resource for Mapping and Three-Dimensional Modeling of Missense SNPs on Human Protein Structures.

Comput Struct Biotechnol J 2015 30;13:514-9. Epub 2015 Sep 30.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA; Innovation Center for Biomedical Informatics, Georgetown University Medical Center, Washington, DC 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.csbj.2015.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759123PMC
March 2016

Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.

Oncotarget 2016 Mar;7(10):11165-93

Innovation Center for Biomedical Informatics (ICBI), Georgetown University Medical Center, Washington, District of Columbia 20007, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.7163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905465PMC
March 2016

A case study for cloud based high throughput analysis of NGS data using the globus genomics system.

Comput Struct Biotechnol J 2015 7;13:64-74. Epub 2014 Nov 7.

Innovation Center for Biomedical Informatics (ICBI), Georgetown University, Washington, DC 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.csbj.2014.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720014PMC
February 2016

The CPTAC Data Portal: A Resource for Cancer Proteomics Research.

J Proteome Res 2015 Jun 4;14(6):2707-13. Epub 2015 May 4.

‡ESAC, Inc., Rockville, Maryland 20850, United States.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/pr501254j
Publisher Site
http://dx.doi.org/10.1021/pr501254jDOI Listing
June 2015

ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer.

J Exp Clin Cancer Res 2015 May 15;34:45. Epub 2015 May 15.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington DC, 20057, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13046-015-0150-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436109PMC
May 2015

In silico analysis of autoimmune diseases and genetic relationships to vaccination against infectious diseases.

BMC Immunol 2014 Dec 9;15:61. Epub 2014 Dec 9.

Innovation Center for Biomedical Informatics, Georgetown University Medical Center, 2115 Wisconsin Ave NW, Suite 110, Washington, DC, 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12865-014-0061-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266212PMC
December 2014

AISAIC: a software suite for accurate identification of significant aberrations in cancers.

Bioinformatics 2014 Feb 29;30(3):431-3. Epub 2013 Nov 29.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, School of Computer Science and Technology, Xidian University, Xi'an 710126, China, Department of Oncology and Department of Gynecology/Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA Department of Oncology and Department of Physiology and Biophysics, Georgetown University, Washington, DC 20057, USA and Department of Electrical Engineering and Computer Science, University of Michigan, An Arbor, MI 48109, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btt693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904524PMC
February 2014

Pharmacogenomic characterization of gemcitabine response--a framework for data integration to enable personalized medicine.

Pharmacogenet Genomics 2014 Feb;24(2):81-93

aInnovation Center for Biomedical Informatics bLombardi Comprehensive Cancer Center, Developmental Therapeutics Program cDepartment of Neurology, Georgetown University Medical Center dDepartment of Mathematics and Statistics, Georgetown University, Washington, District of Columbia eESAC Inc., Rockville fUS Food and Drug Administration, Silver Spring, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888473PMC
February 2014

Platform for Personalized Oncology: Integrative analyses reveal novel molecular signatures associated with colorectal cancer relapse.

AMIA Jt Summits Transl Sci Proc 2013 18;2013:118. Epub 2013 Mar 18.

Innovation Center for Biomedical Informatics, Georgetown University, Washington DC, USA.

View Article

Download full-text PDF

Source
December 2013

Genome-wide multi-omics profiling of colorectal cancer identifies immune determinants strongly associated with relapse.

Front Genet 2013 20;4:236. Epub 2013 Nov 20.

Department of Oncology, Innovation Center for Biomedical Informatics, Georgetown University Medical Center Washington, DC, USA ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center Washington DC, USA.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fgene.2013.00
Publisher Site
http://dx.doi.org/10.3389/fgene.2013.00236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834519PMC
December 2013

In silico discovery of mitosis regulation networks associated with early distant metastases in estrogen receptor positive breast cancers.

Cancer Inform 2013 13;12:31-51. Epub 2013 Feb 13.

Innovation Center for Biomedical Informatics, Georgetown University Medical Center, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/CIN.S10329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579429PMC
March 2013

Preclinical magnetic resonance imaging and systems biology in cancer research: current applications and challenges.

Am J Pathol 2013 Feb 4;182(2):312-8. Epub 2012 Dec 4.

Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University Medical Center, Washington, District of Columbia 20057, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029440120081
Publisher Site
http://dx.doi.org/10.1016/j.ajpath.2012.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969503PMC
February 2013

Predicting new indications for approved drugs using a proteochemometric method.

J Med Chem 2012 Aug 25;55(15):6832-48. Epub 2012 Jul 25.

Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center , Washington, DC 20057, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm300576qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419493PMC
August 2012

Informatics and data quality at collaborative multicenter Breast and Colon Cancer Family Registries.

J Am Med Inform Assoc 2012 Jun 9;19(e1):e125-8. Epub 2012 Feb 9.

Clinical Research Informatics, Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/amiajnl-2011-000546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392863PMC
June 2012

Pediatric palliative care and eHealth opportunities for patient-centered care.

Am J Prev Med 2011 May;40(5 Suppl 2):S208-16

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street NW, Washington, DC 20007, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amepre.2011.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703627PMC
May 2011

DDN: a caBIG® analytical tool for differential network analysis.

Bioinformatics 2011 Apr 3;27(7):1036-8. Epub 2011 Feb 3.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btr052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065688PMC
April 2011

PUGSVM: a caBIG™ analytical tool for multiclass gene selection and predictive classification.

Bioinformatics 2011 Mar 24;27(5):736-8. Epub 2010 Dec 24.

Bradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btq721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042183PMC
March 2011

Rembrandt: helping personalized medicine become a reality through integrative translational research.

Mol Cancer Res 2009 Feb 10;7(2):157-67. Epub 2009 Feb 10.

Center for Biomedical Informatics and Information Technology, Neuro-Oncology Branch, National Cancer Institute, Bethesda, MD 20892, USA.

View Article

Download full-text PDF

Source
http://mcr.aacrjournals.org/cgi/doi/10.1158/1541-7786.MCR-08
Publisher Site
http://dx.doi.org/10.1158/1541-7786.MCR-08-0435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645472PMC
February 2009