Publications by authors named "Subburaman Mohan"

100Publications

CCN1/Cyr61 Is Required in Osteoblasts for Responsiveness to the Anabolic Activity of PTH.

J Bone Miner Res 2020 Nov 17;35(11):2289-2300. Epub 2020 Aug 17.

Department of Orthopaedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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November 2020

A segmental defect adaptation of the mouse closed femur fracture model for the analysis of severely impaired bone healing.

Animal Model Exp Med 2020 Jun 1;3(2):130-139. Epub 2020 May 1.

Musculoskeletal Disease Center Research Service (151) Jerry L. Pettis Memorial Veterans Administration Medical Center Loma Linda CA USA.

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June 2020

Growth Hormone Effects on Bone Loss-Induced by Mild Traumatic Brain Injury and/or Hind Limb Unloading.

Sci Rep 2019 12 12;9(1):18995. Epub 2019 Dec 12.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, 92357, USA.

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December 2019

Vitamin C effects on 5-hydroxymethylcytosine and gene expression in osteoblasts and chondrocytes: Potential involvement of PHD2.

PLoS One 2019 7;14(8):e0220653. Epub 2019 Aug 7.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, United States of America.

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March 2020

Skeletal effects of nongenomic thyroid hormone receptor beta signaling.

J Endocrinol 2019 09;242(3):173-183

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, California, USA.

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September 2019

Novel Role for Claudin-11 in the Regulation of Osteoblasts via Modulation of ADAM10-Mediated Notch Signaling.

J Bone Miner Res 2019 10 26;34(10):1910-1922. Epub 2019 Jul 26.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.

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October 2019

Chemokine receptor 3 is a negative regulator of trabecular bone mass in female mice.

J Cell Biochem 2019 08 11;120(8):13974-13984. Epub 2019 Apr 11.

Musculoskeletal Disease Center, Research Service, LLVARE, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, California.

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August 2019

Changes in ephrin gene expression during bone healing identify a restricted repertoire of ephrins mediating fracture repair.

Histochem Cell Biol 2019 Jan 24;151(1):43-55. Epub 2018 Sep 24.

Musculoskeletal Disease Center, Research Service (151), Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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January 2019

The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification.

Bone Res 2018 14;6:19. Epub 2018 Jun 14.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California USA.

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June 2018

Role of IGF1 and EFN-EPH signaling in skeletal metabolism.

J Mol Endocrinol 2018 07 26;61(1):T87-T102. Epub 2018 Mar 26.

Musculoskeletal Disease CenterVA Loma Linda Healthcare System, Loma Linda, California, USA

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July 2018

Long-term Consequences of Traumatic Brain Injury in Bone Metabolism.

Front Neurol 2018 5;9:115. Epub 2018 Mar 5.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, United States.

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March 2018

Thyroid Hormone Signaling in the Development of the Endochondral Skeleton.

Vitam Horm 2018 6;106:351-381. Epub 2017 Sep 6.

Musculoskeletal Disease Center, Loma Linda VA Healthcare System, Loma Linda, CA, United States; Loma Linda University School of Medicine, Loma Linda, CA, United States. Electronic address:

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October 2018

Cortical and trabecular bone are equally affected in rats with renal failure and secondary hyperparathyroidism.

BMC Nephrol 2018 02 2;19(1):24. Epub 2018 Feb 2.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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February 2018

CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance.

J Bone Miner Res 2018 06 5;33(6):1076-1089. Epub 2018 Mar 5.

Department of Orthopaedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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June 2018

Experimental repetitive mild traumatic brain injury induces deficits in trabecular bone microarchitecture and strength in mice.

Bone Res 2017 19;5:17042. Epub 2017 Dec 19.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.

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December 2017

Effect of Altering Dietary n-6:n-3 Polyunsaturated Fatty Acid Ratio with Plant and Marine-Based Supplement on Biomarkers of Bone Turnover in Healthy Adults.

Nutrients 2017 Oct 24;9(10). Epub 2017 Oct 24.

Center for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA.

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October 2017

IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots.

Endocrinology 2017 10;158(10):3488-3500

Maine Medical Center Research Institute, Scarborough, Maine 04074.

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October 2017

Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation.

Sci Rep 2017 09 5;7(1):10432. Epub 2017 Sep 5.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California, United States.

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September 2017

Lmx1b-targeted -regulatory modules involved in limb dorsalization.

Development 2017 06 28;144(11):2009-2020. Epub 2017 Apr 28.

Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA 92354, USA

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June 2017

Conditional Deletion of the Phd2 Gene in Articular Chondrocytes Accelerates Differentiation and Reduces Articular Cartilage Thickness.

Sci Rep 2017 03 28;7:45408. Epub 2017 Mar 28.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA 92357, USA.

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March 2017

Role and mechanism of action of leucine-rich repeat kinase 1 in bone.

Bone Res 2017 14;5:17003. Epub 2017 Mar 14.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA; Department of Medicine, Loma Linda University, Loma Linda, CA, USA.

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March 2017

Thyroid hormone acting via TRβ induces expression of browning genes in mouse bone marrow adipose tissue.

Endocrine 2017 Apr 22;56(1):109-120. Epub 2017 Feb 22.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.

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April 2017

IGFBP-4 regulates adult skeletal growth in a sex-specific manner.

J Endocrinol 2017 04 9;233(1):131-144. Epub 2017 Feb 9.

Maine Medical Center Research InstituteScarborough, Maine, USA.

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April 2017

Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice.

Sci Rep 2016 10 24;6:35748. Epub 2016 Oct 24.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA 92357, USA.

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October 2016

Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation.

Am J Physiol Endocrinol Metab 2016 10 6;311(4):E772-E780. Epub 2016 Sep 6.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California; Department of Medicine, Loma Linda University, Loma Linda, California;

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October 2016

Effects of Thyroxine (T4), 3,5,3'-triiodo-L-thyronine (T3) and their Metabolites on Osteoblast Differentiation.

Calcif Tissue Int 2016 10 16;99(4):435-42. Epub 2016 Jun 16.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, 11201 Benton St, Loma Linda, CA, 92357, USA.

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October 2016

Bidirectional ephrin signaling in bone.

Osteoporos Sarcopenia 2016 Jun 7;2(2):65-76. Epub 2016 Jun 7.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, 11201 Benton St, Loma Linda, CA 92357, USA.

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June 2016

Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity.

J Med Genet 2016 08 7;53(8):568-74. Epub 2016 Apr 7.

Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan Department of Orthopaedics, National Rehabilitation Center for Disabled Children, Tokyo, Japan.

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August 2016

Thyroid hormone receptor-β1 signaling is critically involved in regulating secondary ossification via promoting transcription of the Ihh gene in the epiphysis.

Am J Physiol Endocrinol Metab 2016 05 29;310(10):E846-54. Epub 2016 Mar 29.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California; Department of Medicine, Loma Linda University, Loma Linda, California; Department of Orthopedics, Loma Linda University, Loma Linda, California; and Department of Biochemistry, Loma Linda University, Loma Linda, California

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May 2016

Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.

Growth Horm IGF Res 2016 Apr 31;27:7-17. Epub 2015 Dec 31.

David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology New York University College of Dentistry New York, NY 10010-408, US. Electronic address:

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April 2016

Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.

Endocrinology 2016 Jan 12;157(1):127-40. Epub 2015 Nov 12.

Musculoskeletal Disease Center (S.C., W.X., S.P., J.S., S.M.), Jerry L. Pettis Veterans Affairs Medical Center, Loma Linda, California 92357; and Department of Medicine (W.X., S.M.), Loma Linda University, Loma Linda, California 92354.

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January 2016

Skeletal effects of growth hormone and insulin-like growth factor-I therapy.

Mol Cell Endocrinol 2016 09 25;432:44-55. Epub 2015 Sep 25.

Musculoskeletal Disease Center, Loma Linda VA Healthcare System, Loma Linda, CA 92357, USA; Department of Medicine, Loma Linda University, Loma Linda, CA 92354, USA; Department of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA. Electronic address:

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September 2016

The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments.

J Bone Miner Res 2015 Nov 7;30(11):1945-55. Epub 2015 Oct 7.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, CA, USA.

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November 2015

RE1-Silencing Transcription Factor (Rest) is a Novel Regulator of Osteoblast Differentiation.

J Cell Biochem 2015 Sep;116(9):1932-8

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California.

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September 2015

Role of WNT16 in the regulation of periosteal bone formation in female mice.

Endocrinology 2015 Mar 18;156(3):1023-32. Epub 2014 Dec 18.

Musculoskeletal Disease Center (J.E.W., C.K., S.D., S.M.), VA Loma Linda Healthcare System, Loma Linda, California 92354; Departments of Medicine (J.E.W., C.K., S.M.), Biochemistry (J.E.W., S.M.), and Physiology (S.M.), Loma Linda University, Loma Linda, California 92357; and Metabolism (R.B.), Lexicon Pharmaceuticals, The Woodlands, Texas 77381.

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March 2015

Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise.

Physiol Genomics 2015 Feb 9;47(2):33-43. Epub 2014 Dec 9.

Musculoskeletal Disease Center, JLP VA Medical Center, Loma Linda, California; and Department of Medicine, Loma Linda University, Loma Linda, California

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February 2015

Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis.

PLoS One 2014 5;9(12):e114357. Epub 2014 Dec 5.

Musculoskeletal Disease Center, Jerry L Pettis VA Med Ctr, Loma Linda, CA 92357, United States of America; Department of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America; Department of Biochemistry, Loma Linda University, Loma Linda, CA 92354, United States of America; Department of Physiology, Loma Linda University, Loma Linda, CA 92354, United States of America.

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December 2015

Emerging multifunctional roles of Claudin tight junction proteins in bone.

Endocrinology 2014 Jul 23;155(7):2363-76. Epub 2014 Apr 23.

Musculoskeletal Disease Center (F.Z.A., S.M.), Jerry L. Pettis VA Medical Center, Loma Linda, CA 92357; Departments of Medicine (S.M.), Biochemistry (S.M.), Physiology (S.M.), and Pharmacology (F.Z.A., S.M.), Loma Linda University, Loma Linda, California 92354.

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July 2014

Conditional disruption of the prolyl hydroxylase domain-containing protein 2 (Phd2) gene defines its key role in skeletal development.

J Bone Miner Res 2014 Oct;29(10):2276-86

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, CA, USA.

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October 2014

Epiphyseal chondrocyte secondary ossification centers require thyroid hormone activation of Indian hedgehog and osterix signaling.

J Bone Miner Res 2014 Oct;29(10):2262-75

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA; Department of Medicine, Loma Linda University, Loma Linda, CA, USA.

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October 2014

A high-calcium diet failed to rescue an osteopenia phenotype in claudin-18 knockout mice.

Physiol Rep 2014 Jan 13;2(1):e00200. Epub 2014 Jan 13.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, 92357, California ; Department of Medicine, Loma Linda University, Loma Linda, 92354, California ; Department of Biochemistry, Loma Linda University, Loma Linda, 92354, California ; Department of Physiology, Loma Linda University, Loma Linda, 92354, California.

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January 2014

In vivo evidence of IGF-I-estrogen crosstalk in mediating the cortical bone response to mechanical strain.

Bone Res 2014 29;2:14007. Epub 2014 Apr 29.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System , Loma Linda, CA, USA ; Department of Medicine, Loma Linda University , Loma Linda, CA, USA.

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August 2015

The negative impact of traumatic brain injury (TBI) on bone in a mouse model.

Brain Inj 2014 2;28(2):244-51. Epub 2013 Dec 2.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center , Loma Linda, CA , USA and.

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October 2014

ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size.

Physiol Genomics 2013 Dec 22;45(24):1222-8. Epub 2013 Oct 22.

Musculoskeletal Disease Center, Loma Linda VA Health Care Systems, Loma Linda, California;

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December 2013

Duffy antigen receptor for chemokines regulates post-fracture inflammation.

PLoS One 2013 17;8(10):e77362. Epub 2013 Oct 17.

Musculoskeletal Disease Center, Research Service, Jerry L Pettis Memorial Veterans Administration Medical Center, Loma Linda, California, United States of America ; Department of Medicine, Loma Linda University, Loma Linda, California, United States of America.

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August 2014

EphA4 receptor is a novel negative regulator of osteoclast activity.

J Bone Miner Res 2014 Apr;29(4):804-19

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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April 2014

Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice.

Physiol Genomics 2013 Oct 13;45(19):917-23. Epub 2013 Aug 13.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;

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October 2013

Transgenic overexpression of ephrin b1 in bone cells promotes bone formation and an anabolic response to mechanical loading in mice.

PLoS One 2013 11;8(7):e69051. Epub 2013 Jul 11.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America.

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April 2014

Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development.

Bone Res 2013 Jun 28;1(2):146-61. Epub 2013 Jun 28.

Musculoskeletal Disease Center, Loma Linda VA HealthCare System , Loma Linda, CA 92357, USA ; Departments of Medicine, Loma Linda University , Loma Linda, CA 92354, USA.

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June 2013

Urokinase plasminogen activator gene deficiency inhibits fracture cartilage remodeling.

J Bone Miner Metab 2014 Mar 23;32(2):124-35. Epub 2013 May 23.

Musculoskeletal Disease Center, Research Service (151), Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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March 2014

The negative impact of single prolonged stress (SPS) on bone development in mice.

Stress 2013 Sep 20;16(5):564-70. Epub 2013 Jun 20.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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September 2013

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis.

J Bone Miner Res 2013 Sep;28(9):1962-74

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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September 2013

Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice.

Am J Physiol Endocrinol Metab 2013 Mar 8;304(5):E531-7. Epub 2013 Jan 8.

Musculoskeletal Disease Center, Loma Linda Veterans Affairs Healthcare System, Loma Linda, CA 923257, USA.

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March 2013

Identification of gender-specific candidate genes that influence bone microarchitecture in chromosome 1.

Calcif Tissue Int 2013 Apr 22;92(4):362-71. Epub 2012 Dec 22.

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, Benton St. (151), 11201, Loma Linda, CA 92357, USA.

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April 2013

Targeted disruption of TGFBI in mice reveals its role in regulating bone mass and bone size through periosteal bone formation.

Calcif Tissue Int 2012 Jul 27;91(1):81-7. Epub 2012 May 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street (151), Loma Linda, CA 92357, USA.

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July 2012

RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1.

BMC Res Notes 2012 May 16;5:239. Epub 2012 May 16.

Surgical Oncology Laboratory, Loma Linda VA Medical Center, CA 92357, USA.

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May 2012

Role of insulin-like growth factor-1 in the regulation of skeletal growth.

Curr Osteoporos Rep 2012 Jun;10(2):178-86

Musculoskeletal Disease Center, Research Service (151), Jerry L Pettis VA Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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June 2012

Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.

PLoS One 2012 20;7(4):e35280. Epub 2012 Apr 20.

Regenerative Medicine Division, Department of Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America.

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August 2012

Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation.

J Bone Miner Res 2012 Jul;27(7):1553-65

Musculoskeletal Disease Center, Jerry L Pettis Memorial Veterans Affairs Medical Center, Loma Linda, CA 92357, USA.

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July 2012

Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice.

PLoS One 2012 5;7(3):e32887. Epub 2012 Mar 5.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America.

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July 2012

Metabolic control and bone health in adolescents with type 1 diabetes.

Int J Pediatr Endocrinol 2011 Oct 26;2011(1):13. Epub 2011 Oct 26.

Department of Pediatrics, Division of Endocrinology and Diabetes, Vanderbilt Children's Hospital, Nashville, TN, USA.

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October 2011

Bone density phenotypes in mice aneuploid for the Down syndrome critical region.

Am J Med Genet A 2011 Oct 13;155A(10):2436-45. Epub 2011 Sep 13.

Musculoskeletal Disease Center, Loma Linda University, California, USA.

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October 2011

Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading.

Am J Physiol Endocrinol Metab 2011 Dec 30;301(6):E1191-7. Epub 2011 Aug 30.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California, USA.

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December 2011

Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation.

Am J Physiol Endocrinol Metab 2011 Jul 5;301(1):E40-8. Epub 2011 Apr 5.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California 92357, USA.

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July 2011

Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway.

Physiol Genomics 2011 Jun 5;43(12):749-57. Epub 2011 Apr 5.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, California, USA.

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June 2011

The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice.

Calcif Tissue Int 2011 Jan 27;88(1):1-8. Epub 2010 Nov 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center and Loma Linda University, Loma Linda, CA 92357, USA.

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January 2011

Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis.

BMC Cancer 2010 Oct 18;10:562. Epub 2010 Oct 18.

Surgical Oncology Laboratory, 11201 Benton Street (151), Loma Linda VA Medical Center, California 92350, USA.

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October 2010

A genomic imprinting defect in mice traced to a single gene.

Genetics 2010 Nov 16;186(3):917-27. Epub 2010 Aug 16.

Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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November 2010

The role of estrogen receptor α in growth plate cartilage for longitudinal bone growth.

J Bone Miner Res 2010 Dec 18;25(12):2690-700. Epub 2010 Jun 18.

Centre for Bone and Arthritis Research, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy, Göteborg, Sweden.

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December 2010

The IGF/IGFBP system in relation to macroscopic bone architecture in pediatric renal transplant patients.

Pediatr Nephrol 2010 Apr 22;25(4):659-67. Epub 2009 Dec 22.

University Children's Hospital, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.

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April 2010

Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1.

Mol Cell Biol 2010 Feb 7;30(3):711-21. Epub 2009 Dec 7.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, CA 92357, USA

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February 2010

Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.

Physiol Genomics 2010 Jan 3;40(2):100-10. Epub 2009 Nov 3.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda University, Loma Linda, CA 92357, USA.

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January 2010

Stem cell antigen-1+ cell-based bone morphogenetic protein-4 gene transfer strategy in mice failed to promote endosteal bone formation.

J Gene Med 2009 Oct;11(10):877-88

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street, Loma Linda, California 92357, USA.

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October 2009

The role of liver-derived insulin-like growth factor-I.

Endocr Rev 2009 Aug 9;30(5):494-535. Epub 2009 Jul 9.

Division of Endocrinology, Institute of Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

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August 2009

Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.

Bone 2009 May 14;44(5):795-804. Epub 2009 Jan 14.

Musculoskeletal Disease Center, Jerry L Pettis Memorial Veterans Affairs Medical Center, Loma Linda, CA 92357, USA.

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May 2009

Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene.

BMC Res Notes 2008 Dec 1;1:124. Epub 2008 Dec 1.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, USA.

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December 2008

Fracture healing in mice deficient in plasminogen activator inhibitor-1.

Calcif Tissue Int 2008 Oct 27;83(4):276-84. Epub 2008 Sep 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA 92357, USA.

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October 2008

Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.

Am J Physiol Endocrinol Metab 2008 Nov 23;295(5):E1172-80. Epub 2008 Sep 23.

Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California 92357, USA.

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November 2008

Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis.

Bone 2008 Nov 29;43(5):880-8. Epub 2008 Jul 29.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Administration Medical Center (151), 11201 Benton Street, Loma Linda, CA 92357, USA.

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November 2008

Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity.

FEBS Lett 2008 Apr 31;582(10):1451-8. Epub 2008 Mar 31.

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA 92357, USA.

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April 2008

Mapping of the chromosome 17 BMD QTL in the F(2) male mice of MRL/MpJ x SJL/J.

Genetica 2009 Jan 11;135(1):59-66. Epub 2008 Mar 11.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA 92357, USA.

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January 2009

Model-based comparative prediction of transcription-factor binding motifs in anabolic responses in bone.

Genomics Proteomics Bioinformatics 2007 Dec;5(3-4):158-65

Department of Biomedical Engineering, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.

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December 2007

A chemical mutagenesis screen to identify modifier genes that interact with growth hormone and TGF-beta signaling pathways.

Bone 2008 Feb 28;42(2):388-95. Epub 2007 Oct 28.

Musculoskeletal Disease Center, Loma Linda VA Health Care Systems, Loma Linda, CA 92357, USA.

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February 2008

Mouse chromosome 9 quantitative trait loci for soft tissue regeneration: congenic analysis and fine mapping.

Wound Repair Regen 2007 Nov-Dec;15(6):922-7

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, California 92357, USA.

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March 2008