Subburaman Mohan

Musculoskeletal Disease Center, Research Service (151), Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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January 2019

LRRK1 regulation of actin assembly in osteoclasts involves serine 5 phosphorylation of L-plastin.

Authors:

Mingjue Si Helen Goodluck Canjun Zeng Songqin Pan Elizabeth M Todd Sharon Celeste Morley Xuezhong Qin Subburaman Mohan Weirong Xing

J Cell Biochem 2018 12 22;119(12):10351-10357. Epub 2018 Aug 22.

Department of Medicine, Loma Linda University, Loma Linda, California.

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December 2018

The art of building bone: emerging role of chondrocyte-to-osteoblast transdifferentiation in endochondral ossification.

Authors:

Patrick Aghajanian Subburaman Mohan

Bone Res 2018 14;6:19. Epub 2018 Jun 14.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California USA.

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June 2018

Role of IGF1 and EFN-EPH signaling in skeletal metabolism.

Authors:

Richard C Lindsey Charles H Rundle Subburaman Mohan

J Mol Endocrinol 2018 07 26;61(1):T87-T102. Epub 2018 Mar 26.

Musculoskeletal Disease CenterVA Loma Linda Healthcare System, Loma Linda, California, USA

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July 2018

Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice.

Authors:

Mariam Choudry Xiaolei Tang Tiffany Santorian Samiksha Wasnik Jidong Xiao Weirong Xing Kin-Hing William Lau Subburaman Mohan David J Baylink Xuezhong Qin

Immunology 2018 09 16;155(1):85-98. Epub 2018 Apr 16.

J. L Pettis VA Medical Center, Loma Linda, CA, USA.

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September 2018

Long-term Consequences of Traumatic Brain Injury in Bone Metabolism.

Authors:

Nikita M Bajwa Chandrasekhar Kesavan Subburaman Mohan

Front Neurol 2018 5;9:115. Epub 2018 Mar 5.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, United States.

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March 2018

Thyroid Hormone Signaling in the Development of the Endochondral Skeleton.

Authors:

Richard C Lindsey Patrick Aghajanian Subburaman Mohan

Vitam Horm 2018 6;106:351-381. Epub 2017 Sep 6.

Musculoskeletal Disease Center, Loma Linda VA Healthcare System, Loma Linda, CA, United States; Loma Linda University School of Medicine, Loma Linda, CA, United States. Electronic address:

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October 2018

Cortical and trabecular bone are equally affected in rats with renal failure and secondary hyperparathyroidism.

Authors:

Nikita M Bajwa Cheryl P Sanchez Richard C Lindsey Heather Watt Subburaman Mohan

BMC Nephrol 2018 02 2;19(1):24. Epub 2018 Feb 2.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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February 2018

CYR61/CCN1 Regulates Sclerostin Levels and Bone Maintenance.

Authors:

Gexin Zhao Bau-Lin Huang Diana Rigueur Weiguang Wang Chimay Bhoot Kemberly R Charles Jongseung Baek Subburaman Mohan Jie Jiang Karen M Lyons

J Bone Miner Res 2018 06 5;33(6):1076-1089. Epub 2018 Mar 5.

Department of Orthopaedic Surgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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June 2018

Experimental repetitive mild traumatic brain injury induces deficits in trabecular bone microarchitecture and strength in mice.

Authors:

Chandrasekhar Kesavan Nikita M Bajwa Heather Watt Subburaman Mohan

Bone Res 2017 19;5:17042. Epub 2017 Dec 19.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.

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December 2017

Effect of Altering Dietary n-6:n-3 Polyunsaturated Fatty Acid Ratio with Plant and Marine-Based Supplement on Biomarkers of Bone Turnover in Healthy Adults.

Authors:

Sujatha Rajaram Ellen Lan Yip Rajneesh Reghunathan Subburaman Mohan Joan Sabaté

Nutrients 2017 Oct 24;9(10). Epub 2017 Oct 24.

Center for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, USA.

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October 2017

IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots.

Authors:

David E Maridas Victoria E DeMambro Phuong T Le Subburaman Mohan Clifford J Rosen

Endocrinology 2017 10;158(10):3488-3500

Maine Medical Center Research Institute, Scarborough, Maine 04074.

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October 2017

Epiphyseal bone formation occurs via thyroid hormone regulation of chondrocyte to osteoblast transdifferentiation.

Authors:

Patrick Aghajanian Weirong Xing Shaohong Cheng Subburaman Mohan

Sci Rep 2017 09 5;7(1):10432. Epub 2017 Sep 5.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California, United States.

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September 2017

Erratum: Role and mechanism of action of leucine-rich repeat kinase 1 in bone.

Authors:

Weirong Xing Helen Goodluck Canjun Zeng Subburaman Mohan

Bone Res 2017 18;5:17029. Epub 2017 Apr 18.

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April 2017

Lmx1b-targeted -regulatory modules involved in limb dorsalization.

Authors:

Endika Haro Billy A Watson Jennifer M Feenstra Luke Tegeler Charmaine U Pira Subburaman Mohan Kerby C Oberg

Development 2017 06 28;144(11):2009-2020. Epub 2017 Apr 28.

Department of Pathology and Human Anatomy, Loma Linda University, Loma Linda, CA 92354, USA

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June 2017

Genetic Knockout and Rescue Studies in Mice Unravel Abnormal Phosphorus Threshold in Hypophosphatemic Rickets.

Authors:

Cheryl P Sanchez Subburaman Mohan

Endocrinology 2017 03;158(3):455-457

Medicine, and.

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March 2017

Conditional Deletion of the Phd2 Gene in Articular Chondrocytes Accelerates Differentiation and Reduces Articular Cartilage Thickness.

Authors:

Shaohong Cheng Sheila Pourteymoor Catrina Alarcon Subburaman Mohan

Sci Rep 2017 03 28;7:45408. Epub 2017 Mar 28.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA 92357, USA.

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March 2017

Role and mechanism of action of leucine-rich repeat kinase 1 in bone.

Authors:

Weirong R Xing Helen Goodluck Canjun Zeng Subburaman Mohan

Bone Res 2017 14;5:17003. Epub 2017 Mar 14.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA; Department of Medicine, Loma Linda University, Loma Linda, CA, USA.

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March 2017

Thyroid hormone acting via TRβ induces expression of browning genes in mouse bone marrow adipose tissue.

Authors:

Richard C Lindsey Subburaman Mohan

Endocrine 2017 Apr 22;56(1):109-120. Epub 2017 Feb 22.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA, USA.

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April 2017

IGFBP-4 regulates adult skeletal growth in a sex-specific manner.

Authors:

David E Maridas Victoria E DeMambro Phuong T Le Kenichi Nagano Roland Baron Subburaman Mohan Clifford J Rosen

J Endocrinol 2017 04 9;233(1):131-144. Epub 2017 Feb 9.

Maine Medical Center Research InstituteScarborough, Maine, USA.

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April 2017

Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Regulates Chondrocyte Differentiation and Secondary Ossification in Mice.

Authors:

Shaohong Cheng Patrick Aghajanian Sheila Pourteymoor Catrina Alarcon Subburaman Mohan

Sci Rep 2016 10 24;6:35748. Epub 2016 Oct 24.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, 11201 Benton Street, Loma Linda, CA 92357, USA.

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October 2016

Leucine-rich repeat kinase-1 regulates osteoclast function by modulating RAC1/Cdc42 Small GTPase phosphorylation and activation.

Authors:

Canjun Zeng Helen Goodluck Xuezhong Qin Bo Liu Subburaman Mohan Weirong Xing

Am J Physiol Endocrinol Metab 2016 10 6;311(4):E772-E780. Epub 2016 Sep 6.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California; Department of Medicine, Loma Linda University, Loma Linda, California;

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October 2016

Effects of Thyroxine (T4), 3,5,3'-triiodo-L-thyronine (T3) and their Metabolites on Osteoblast Differentiation.

Authors:

Shaohong Cheng Weirong Xing Sheila Pourteymoor Subburaman Mohan

Calcif Tissue Int 2016 10 16;99(4):435-42. Epub 2016 Jun 16.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, 11201 Benton St, Loma Linda, CA, 92357, USA.

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October 2016

Bidirectional ephrin signaling in bone.

Authors:

Charles H Rundle Weirong Xing Kin-Hing William Lau Subburaman Mohan

Osteoporos Sarcopenia 2016 Jun 7;2(2):65-76. Epub 2016 Jun 7.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, 11201 Benton St, Loma Linda, CA 92357, USA.

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June 2016

Identification of biallelic LRRK1 mutations in osteosclerotic metaphyseal dysplasia and evidence for locus heterogeneity.

Authors:

Aritoshi Iida Weirong Xing Martine K F Docx Tomoki Nakashima Zheng Wang Mamori Kimizuka Wim Van Hul Dietz Rating Jürgen Spranger Hirohumi Ohashi Noriko Miyake Naomichi Matsumoto Subburaman Mohan Gen Nishimura Geert Mortier Shiro Ikegawa

J Med Genet 2016 08 7;53(8):568-74. Epub 2016 Apr 7.

Laboratory for Bone and Joint Diseases, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan Department of Orthopaedics, National Rehabilitation Center for Disabled Children, Tokyo, Japan.

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August 2016

Thyroid hormone receptor-β1 signaling is critically involved in regulating secondary ossification via promoting transcription of the Ihh gene in the epiphysis.

Authors:

Weirong Xing Patrick Aghajanian Helen Goodluck Chandrasekhar Kesavan Shaohong Cheng Sheila Pourteymoor Heather Watt Catrina Alarcon Subburaman Mohan

Am J Physiol Endocrinol Metab 2016 05 29;310(10):E846-54. Epub 2016 Mar 29.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California; Department of Medicine, Loma Linda University, Loma Linda, California; Department of Orthopedics, Loma Linda University, Loma Linda, California; and Department of Biochemistry, Loma Linda University, Loma Linda, California

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May 2016

Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies.

Authors:

Zhongbo Liu Subburaman Mohan Shoshana Yakar

Growth Horm IGF Res 2016 Apr 31;27:7-17. Epub 2015 Dec 31.

David B. Kriser Dental Center, Department of Basic Science and Craniofacial Biology New York University College of Dentistry New York, NY 10010-408, US. Electronic address:

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April 2016

Conditional Deletion of Prolyl Hydroxylase Domain-Containing Protein 2 (Phd2) Gene Reveals Its Essential Role in Chondrocyte Function and Endochondral Bone Formation.

Authors:

Shaohong Cheng Weirong Xing Sheila Pourteymoor Jan Schulte Subburaman Mohan

Endocrinology 2016 Jan 12;157(1):127-40. Epub 2015 Nov 12.

Musculoskeletal Disease Center (S.C., W.X., S.P., J.S., S.M.), Jerry L. Pettis Veterans Affairs Medical Center, Loma Linda, California 92357; and Department of Medicine (W.X., S.M.), Loma Linda University, Loma Linda, California 92354.

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January 2016

Skeletal effects of growth hormone and insulin-like growth factor-I therapy.

Authors:

Richard C Lindsey Subburaman Mohan

Mol Cell Endocrinol 2016 09 25;432:44-55. Epub 2015 Sep 25.

Musculoskeletal Disease Center, Loma Linda VA Healthcare System, Loma Linda, CA 92357, USA; Department of Medicine, Loma Linda University, Loma Linda, CA 92354, USA; Department of Biochemistry, Loma Linda University, Loma Linda, CA 92354, USA. Electronic address:

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September 2016

The Roles and Mechanisms of Actions of Vitamin C in Bone: New Developments.

Authors:

Patrick Aghajanian Susan Hall Montri D Wongworawat Subburaman Mohan

J Bone Miner Res 2015 Nov 7;30(11):1945-55. Epub 2015 Oct 7.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, CA, USA.

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November 2015

RE1-Silencing Transcription Factor (Rest) is a Novel Regulator of Osteoblast Differentiation.

Authors:

Bo Liu Shaohong Cheng Weirong Xing Sheila Pourteymoor Subburaman Mohan

J Cell Biochem 2015 Sep;116(9):1932-8

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California.

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September 2015

Role of WNT16 in the regulation of periosteal bone formation in female mice.

Authors:

Jon E Wergedal Chandrasekhar Kesavan Robert Brommage Subhashri Das Subburaman Mohan

Endocrinology 2015 Mar 18;156(3):1023-32. Epub 2014 Dec 18.

Musculoskeletal Disease Center (J.E.W., C.K., S.D., S.M.), VA Loma Linda Healthcare System, Loma Linda, California 92354; Departments of Medicine (J.E.W., C.K., S.M.), Biochemistry (J.E.W., S.M.), and Physiology (S.M.), Loma Linda University, Loma Linda, California 92357; and Metabolism (R.B.), Lexicon Pharmaceuticals, The Woodlands, Texas 77381.

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March 2015

Conditional disruption of miR17-92 cluster in collagen type I-producing osteoblasts results in reduced periosteal bone formation and bone anabolic response to exercise.

Authors:

Subburaman Mohan Jon E Wergedal Subhashri Das Chandrasekhar Kesavan

Physiol Genomics 2015 Feb 9;47(2):33-43. Epub 2014 Dec 9.

Musculoskeletal Disease Center, JLP VA Medical Center, Loma Linda, California; and Department of Medicine, Loma Linda University, Loma Linda, California

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February 2015

Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis.

Authors:

Fatima Z Alshbool Subburaman Mohan

PLoS One 2014 5;9(12):e114357. Epub 2014 Dec 5.

Musculoskeletal Disease Center, Jerry L Pettis VA Med Ctr, Loma Linda, CA 92357, United States of America; Department of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America; Department of Biochemistry, Loma Linda University, Loma Linda, CA 92354, United States of America; Department of Physiology, Loma Linda University, Loma Linda, CA 92354, United States of America.

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December 2015

Emerging multifunctional roles of Claudin tight junction proteins in bone.

Authors:

Fatima Z Alshbool Subburaman Mohan

Endocrinology 2014 Jul 23;155(7):2363-76. Epub 2014 Apr 23.

Musculoskeletal Disease Center (F.Z.A., S.M.), Jerry L. Pettis VA Medical Center, Loma Linda, CA 92357; Departments of Medicine (S.M.), Biochemistry (S.M.), Physiology (S.M.), and Pharmacology (F.Z.A., S.M.), Loma Linda University, Loma Linda, California 92354.

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July 2014

Conditional disruption of the prolyl hydroxylase domain-containing protein 2 (Phd2) gene defines its key role in skeletal development.

Authors:

Shaohong Cheng Weirong Xing Sheila Pourteymoor Subburaman Mohan

J Bone Miner Res 2014 Oct;29(10):2276-86

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, CA, USA.

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October 2014

Epiphyseal chondrocyte secondary ossification centers require thyroid hormone activation of Indian hedgehog and osterix signaling.

Authors:

Weirong Xing Shaohong Cheng Jon Wergedal Subburaman Mohan

J Bone Miner Res 2014 Oct;29(10):2262-75

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA; Department of Medicine, Loma Linda University, Loma Linda, CA, USA.

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October 2014

A high-calcium diet failed to rescue an osteopenia phenotype in claudin-18 knockout mice.

Authors:

Fatima Z Alshbool Catrina Alarcon Jon Wergedal Subburaman Mohan

Physiol Rep 2014 Jan 13;2(1):e00200. Epub 2014 Jan 13.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, 92357, California ; Department of Medicine, Loma Linda University, Loma Linda, 92354, California ; Department of Biochemistry, Loma Linda University, Loma Linda, 92354, California ; Department of Physiology, Loma Linda University, Loma Linda, 92354, California.

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January 2014

In vivo evidence of IGF-I-estrogen crosstalk in mediating the cortical bone response to mechanical strain.

Authors:

Subburaman Mohan Chetan Girijanand Bhat Jon E Wergedal Chandrasekhar Kesavan

Bone Res 2014 29;2:14007. Epub 2014 Apr 29.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System , Loma Linda, CA, USA ; Department of Medicine, Loma Linda University , Loma Linda, CA, USA.

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August 2015

Reduced bone mass accrual in mouse model of repetitive mild traumatic brain injury.

Authors:

Hongrun Yu Jon E Wergedal Charles H Rundle Subburaman Mohan

J Rehabil Res Dev 2014 ;51(9):1427-37

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November 2015

The negative impact of traumatic brain injury (TBI) on bone in a mouse model.

Authors:

Hongrun Yu Heather Watt Subburaman Mohan

Brain Inj 2014 2;28(2):244-51. Epub 2013 Dec 2.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center , Loma Linda, CA , USA and.

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October 2014

ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size.

Authors:

Bouchra Edderkaoui Chandrasekhar Kesavan David J Baylink Jon E Wergedal Apurva K Srivastava Subburaman Mohan

Physiol Genomics 2013 Dec 22;45(24):1222-8. Epub 2013 Oct 22.

Musculoskeletal Disease Center, Loma Linda VA Health Care Systems, Loma Linda, California;

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December 2013

Duffy antigen receptor for chemokines regulates post-fracture inflammation.

Authors:

Charles H Rundle Subburaman Mohan Bouchra Edderkaoui

PLoS One 2013 17;8(10):e77362. Epub 2013 Oct 17.

Musculoskeletal Disease Center, Research Service, Jerry L Pettis Memorial Veterans Administration Medical Center, Loma Linda, California, United States of America ; Department of Medicine, Loma Linda University, Loma Linda, California, United States of America.

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August 2014

EphA4 receptor is a novel negative regulator of osteoclast activity.

Authors:

Virginia Stiffel Mehran Amoui Matilda H-C Sheng Subburaman Mohan K-H William Lau

J Bone Miner Res 2014 Apr;29(4):804-19

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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April 2014

Haploinsufficiency of osterix in chondrocytes impairs skeletal growth in mice.

Authors:

Shaohong Cheng Weirong Xing Xin Zhou Subburaman Mohan

Physiol Genomics 2013 Oct 13;45(19):917-23. Epub 2013 Aug 13.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, California;

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October 2013

Transgenic overexpression of ephrin b1 in bone cells promotes bone formation and an anabolic response to mechanical loading in mice.

Authors:

Shaohong Cheng Chandrasekhar Kesavan Subburaman Mohan Xuezhong Qin Catrina M Alarcon Jon Wergedal Weirong Xing

PLoS One 2013 11;8(7):e69051. Epub 2013 Jul 11.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America.

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April 2014

Role and Mechanisms of Actions of Thyroid Hormone on the Skeletal Development.

Authors:

Ha-Young Kim Subburaman Mohan

Bone Res 2013 Jun 28;1(2):146-61. Epub 2013 Jun 28.

Musculoskeletal Disease Center, Loma Linda VA HealthCare System , Loma Linda, CA 92357, USA ; Departments of Medicine, Loma Linda University , Loma Linda, CA 92354, USA.

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June 2013

Urokinase plasminogen activator gene deficiency inhibits fracture cartilage remodeling.

Authors:

Nicoleta L Popa Jon E Wergedal K-H William Lau Subburaman Mohan Charles H Rundle

J Bone Miner Metab 2014 Mar 23;32(2):124-35. Epub 2013 May 23.

Musculoskeletal Disease Center, Research Service (151), Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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March 2014

The negative impact of single prolonged stress (SPS) on bone development in mice.

Authors:

Hongrun Yu Heather Watt Chandrasekhar Kesavan Subburaman Mohan

Stress 2013 Sep 20;16(5):564-70. Epub 2013 Jun 20.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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September 2013

Targeted disruption of leucine-rich repeat kinase 1 but not leucine-rich repeat kinase 2 in mice causes severe osteopetrosis.

Authors:

Weirong Xing Jeff Liu Shaohong Cheng Peter Vogel Subburaman Mohan Robert Brommage

J Bone Miner Res 2013 Sep;28(9):1962-74

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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September 2013

Disruption of claudin-18 diminishes ovariectomy-induced bone loss in mice.

Authors:

Ha-Young Kim Catrina Alarcon Sheila Pourteymour Jon E Wergedal Subburaman Mohan

Am J Physiol Endocrinol Metab 2013 Mar 8;304(5):E531-7. Epub 2013 Jan 8.

Musculoskeletal Disease Center, Loma Linda Veterans Affairs Healthcare System, Loma Linda, CA 923257, USA.

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March 2013

Identification of gender-specific candidate genes that influence bone microarchitecture in chromosome 1.

Authors:

Subburaman Mohan Yan Hu Bouchra Edderkaoui

Calcif Tissue Int 2013 Apr 22;92(4):362-71. Epub 2012 Dec 22.

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, Benton St. (151), 11201, Loma Linda, CA 92357, USA.

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April 2013

Lasting consequences of traumatic events on behavioral and skeletal parameters in a mouse model for post-traumatic stress disorder (PTSD).

Authors:

Hongrun Yu Heather Watt Chandrasekhar Kesavan Patrick J Johnson Jon E Wergedal Subburaman Mohan

PLoS One 2012 22;7(8):e42684. Epub 2012 Aug 22.

Jerry L. Pettis Memorial VA Medical Center, Loma Linda, California, United States of America.

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January 2013

Transgenic overexpression of pregnancy-associated plasma protein-A in skeletal muscle of mice increases myofiber size and central nucleation in sedentary muscle and promotes muscle regeneration in the injured muscle.

Authors:

Chandra Deb Bo Li David J Baylink Weirong Xing Wenyi Zhang Michael Chen Jon E Wergedal Subburaman Mohan Xuezhong Qin

Growth Horm IGF Res 2012 Oct 17;22(5):173-9. Epub 2012 Jun 17.

Division of Regenerative Medicine, Department of Medicine, Loma Linda University, CA 92354, USA.

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October 2012

Targeted disruption of TGFBI in mice reveals its role in regulating bone mass and bone size through periosteal bone formation.

Authors:

Hongrun Yu Jon E Wergedal Yongliang Zhao Subburaman Mohan

Calcif Tissue Int 2012 Jul 27;91(1):81-7. Epub 2012 May 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street (151), Loma Linda, CA 92357, USA.

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July 2012

RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1.

Authors:

Mark E Reeves Melissa L Baldwin Robert Aragon Scott Baldwin Shin-Tai Chen Xinmin Li Subburaman Mohan Yousef G Amaar

BMC Res Notes 2012 May 16;5:239. Epub 2012 May 16.

Surgical Oncology Laboratory, Loma Linda VA Medical Center, CA 92357, USA.

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May 2012

Role of insulin-like growth factor-1 in the regulation of skeletal growth.

Authors:

Subburaman Mohan Chandrasekhar Kesavan

Curr Osteoporos Rep 2012 Jun;10(2):178-86

Musculoskeletal Disease Center, Research Service (151), Jerry L Pettis VA Medical Center, 11201 Benton Street, Loma Linda, CA, 92357, USA.

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June 2012

Targeted overexpression of osteoactivin in cells of osteoclastic lineage promotes osteoclastic resorption and bone loss in mice.

Authors:

Matilda H-C Sheng Jon E Wergedal Subburaman Mohan Mehran Amoui David J Baylink K-H William Lau

PLoS One 2012 20;7(4):e35280. Epub 2012 Apr 20.

Regenerative Medicine Division, Department of Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America.

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August 2012

Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice.

Authors:

Weirong Xing Kristen E Govoni Leah Rae Donahue Chandrasekhar Kesavan Jon Wergedal Carlin Long J H Duncan Bassett Apostolos Gogakos Anna Wojcicka Graham R Williams Subburaman Mohan

J Bone Miner Res 2012 May;27(5):1067-79

Musculoskeletal Disease Center, Loma Linda VA HealthCare System, Loma Linda, CA 92357, USA.

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May 2012

Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation.

Authors:

Gabriel R Linares Robert Brommage David R Powell Weirong Xing Shin-Tai Chen Fatima Z Alshbool K-H William Lau Jon E Wergedal Subburaman Mohan

J Bone Miner Res 2012 Jul;27(7):1553-65

Musculoskeletal Disease Center, Jerry L Pettis Memorial Veterans Affairs Medical Center, Loma Linda, CA 92357, USA.

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July 2012

Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice.

Authors:

Shaohong Cheng Shien Lucy Zhao Brittany Nelson Chandrasekhar Kesavan Xuezhong Qin Jon Wergedal Subburaman Mohan Weirong Xing

PLoS One 2012 5;7(3):e32887. Epub 2012 Mar 5.

Musculoskeletal Disease Center, Jerry L Pettis VA Medical Center, Loma Linda, California, United States of America.

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July 2012

Metabolic control and bone health in adolescents with type 1 diabetes.

Authors:

Jill H Simmons Miranda Raines Kathryn D Ness Randon Hall Tebeb Gebretsadik Subburaman Mohan Anna Spagnoli

Int J Pediatr Endocrinol 2011 Oct 26;2011(1):13. Epub 2011 Oct 26.

Department of Pediatrics, Division of Endocrinology and Diabetes, Vanderbilt Children's Hospital, Nashville, TN, USA.

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October 2011

Bone density phenotypes in mice aneuploid for the Down syndrome critical region.

Authors:

Lisa E Olson Subburaman Mohan

Am J Med Genet A 2011 Oct 13;155A(10):2436-45. Epub 2011 Sep 13.

Musculoskeletal Disease Center, Loma Linda University, California, USA.

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October 2011

Conditional disruption of IGF-I gene in type 1α collagen-expressing cells shows an essential role of IGF-I in skeletal anabolic response to loading.

Authors:

Chandrasekhar Kesavan Jon E Wergedal K-H William Lau Subburaman Mohan

Am J Physiol Endocrinol Metab 2011 Dec 30;301(6):E1191-7. Epub 2011 Aug 30.

Musculoskeletal Disease Center, Veterans Affairs Loma Linda Healthcare System, Loma Linda, California, USA.

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December 2011

Role of diabetes- and obesity-related protein in the regulation of osteoblast differentiation.

Authors:

Gabriel R Linares Weirong Xing Hans Burghardt Bernhard Baumgartner Shin-Tai Chen Wifredo Ricart José Manuel Fernández-Real Antonio Zorzano Subburaman Mohan

Am J Physiol Endocrinol Metab 2011 Jul 5;301(1):E40-8. Epub 2011 Apr 5.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California 92357, USA.

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July 2011

Ascorbic acid regulates osterix expression in osteoblasts by activation of prolyl hydroxylase and ubiquitination-mediated proteosomal degradation pathway.

Authors:

Weirong Xing Sheila Pourteymoor Subburaman Mohan

Physiol Genomics 2011 Jun 5;43(12):749-57. Epub 2011 Apr 5.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, California, USA.

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June 2011

Stem cell antigen-1 positive cell-based systemic human growth hormone gene transfer strategy increases endosteal bone resorption and bone loss in mice.

Authors:

Susan L Hall Shin-Tai Chen Jon E Wergedal Daila S Gridley Subburaman Mohan K-H William Lau

J Gene Med 2011 Feb;13(2):77-88

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center, Loma Linda, CA, USA.

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February 2011

The role of GH/IGF-I-mediated mechanisms in sex differences in cortical bone size in mice.

Authors:

Lisa E Olson Claes Ohlsson Subburaman Mohan

Calcif Tissue Int 2011 Jan 27;88(1):1-8. Epub 2010 Nov 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial VA Medical Center and Loma Linda University, Loma Linda, CA 92357, USA.

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January 2011

Ras-association domain family 1C protein promotes breast cancer cell migration and attenuates apoptosis.

Authors:

Mark E Reeves Scott W Baldwin Melissa L Baldwin Shin-Tai Chen Jeremy M Moretz Robert J Aragon Xinmin Li Donna D Strong Subburaman Mohan Yousef G Amaar

BMC Cancer 2010 Oct 18;10:562. Epub 2010 Oct 18.

Surgical Oncology Laboratory, 11201 Benton Street (151), Loma Linda VA Medical Center, California 92350, USA.

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October 2010

Leptin receptor (Lepr) is a negative modulator of bone mechanosensitivity and genetic variations in Lepr may contribute to the differential osteogenic response to mechanical stimulation in the C57BL/6J and C3H/HeJ pair of mouse strains.

Authors:

Sonia Kapur Mehran Amoui Chandrasekhar Kesavan Xiaoguang Wang Subburaman Mohan David J Baylink K-H William Lau

J Biol Chem 2010 Nov 17;285(48):37607-18. Epub 2010 Sep 17.

Musculoskeletal Disease Center, Jerry L Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California 92357, USA.

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November 2010

A genomic imprinting defect in mice traced to a single gene.

Authors:

Altan Rentsendorj Subburaman Mohan Piroska Szabó Jeffrey R Mann

Genetics 2010 Nov 16;186(3):917-27. Epub 2010 Aug 16.

Division of Biology, Beckman Research Institute, City of Hope National Medical Center, Duarte, California 91010, USA.

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November 2010

The role of estrogen receptor α in growth plate cartilage for longitudinal bone growth.

Authors:

Anna E Börjesson Marie K Lagerquist Chen Liu Ruijin Shao Sara H Windahl Camilla Karlsson Klara Sjögren Sofia Movérare-Skrtic Maria Christina Antal Andrée Krust Subburaman Mohan Pierre Chambon Lars Sävendahl Claes Ohlsson

J Bone Miner Res 2010 Dec 18;25(12):2690-700. Epub 2010 Jun 18.

Centre for Bone and Arthritis Research, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy, Göteborg, Sweden.

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December 2010

Inactivation of insulin-like-growth factors diminished the anabolic effects of pregnancy-associated plasma protein-A (PAPP-A) on bone in mice.

Authors:

David Phang Mark Rehage Blake Bonafede Diana Hou Weirong Xing Subburaman Mohan Jon E Wergedal Xuezhong Qin

Growth Horm IGF Res 2010 Jun 9;20(3):192-200. Epub 2010 Feb 9.

Musculoskeletal Disease Center, Loma Linda University, Loma Linda, CA 92354, United States.

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June 2010

The IGF/IGFBP system in relation to macroscopic bone architecture in pediatric renal transplant patients.

Authors:

Daniela Kiepe Eva-Maria Rüth Werner F Blum Subburaman Mohan Lutz T Weber Burkhard Tönshoff

Pediatr Nephrol 2010 Apr 22;25(4):659-67. Epub 2009 Dec 22.

University Children's Hospital, Im Neuenheimer Feld 430, 69120 Heidelberg, Germany.

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April 2010

Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1.

Authors:

Weirong Xing Jonghyun Kim Jon Wergedal Shin-Tai Chen Subburaman Mohan

Mol Cell Biol 2010 Feb 7;30(3):711-21. Epub 2009 Dec 7.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda, CA 92357, USA

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February 2010

Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.

Authors:

Jonghyun Kim Weirong Xing Jon Wergedal Jefferson Y Chan Subburaman Mohan

Physiol Genomics 2010 Jan 3;40(2):100-10. Epub 2009 Nov 3.

Musculoskeletal Disease Center, Jerry L. Pettis VA Medical Center, Loma Linda University, Loma Linda, CA 92357, USA.

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January 2010

Marrow stromal cell-based cyclooxygenase 2 ex vivo gene-transfer strategy surprisingly lacks bone-regeneration effects and suppresses the bone-regeneration action of bone morphogenetic protein 4 in a mouse critical-sized calvarial defect model.

Authors:

K-H William Lau Reinhard Gysin Shin-Tai Chen Jon E Wergedal David J Baylink Subburaman Mohan

Calcif Tissue Int 2009 Oct 11;85(4):356-67. Epub 2009 Sep 11.

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street, Loma Linda, CA 92357, USA.

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October 2009

Stem cell antigen-1+ cell-based bone morphogenetic protein-4 gene transfer strategy in mice failed to promote endosteal bone formation.

Authors:

Susan L Hall Shin-Tai Chen Reinhard Gysin Daila S Gridley Subburaman Mohan K-H William Lau

J Gene Med 2009 Oct;11(10):877-88

Musculoskeletal Disease Center (151), Jerry L. Pettis Memorial VA Medical Center, 11201 Benton Street, Loma Linda, California 92357, USA.

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October 2009

The role of liver-derived insulin-like growth factor-I.

Authors:

Claes Ohlsson Subburaman Mohan Klara Sjögren Asa Tivesten Jörgen Isgaard Olle Isaksson John-Olov Jansson Johan Svensson

Endocr Rev 2009 Aug 9;30(5):494-535. Epub 2009 Jul 9.

Division of Endocrinology, Institute of Medicine, Sahlgrenska University Hospital, Göteborg, Sweden.

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August 2009

Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress.

Authors:

Gabriel R Linares Weirong Xing Kristen E Govoni Shin-Tai Chen Subburaman Mohan

Bone 2009 May 14;44(5):795-804. Epub 2009 Jan 14.

Musculoskeletal Disease Center, Jerry L Pettis Memorial Veterans Affairs Medical Center, Loma Linda, CA 92357, USA.

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May 2009

Elevated aromatase expression in osteoblasts leads to increased bone mass without systemic adverse effects.

Authors:

Klara Sjögren Marie Lagerquist Sofia Moverare-Skrtic Niklas Andersson Sara H Windahl Charlotte Swanson Subburaman Mohan Matti Poutanen Claes Ohlsson

J Bone Miner Res 2009 Jul;24(7):1263-70

Center for Bone Research, Institute of Medicine, University of Gothenburg, Sahlgrenska Academy, Göteborg, Sweden.

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July 2009

Lack of anabolic response to skeletal loading in mice with targeted disruption of the pleiotrophin gene.

Authors:

Chandrasekhar Kesavan Subburaman Mohan

BMC Res Notes 2008 Dec 1;1:124. Epub 2008 Dec 1.

Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, USA.

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December 2008

Fracture healing in mice deficient in plasminogen activator inhibitor-1.

Authors:

Charles H Rundle Xiaoguang Wang Jon E Wergedal Subburaman Mohan K-H William Lau

Calcif Tissue Int 2008 Oct 27;83(4):276-84. Epub 2008 Sep 27.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Administration Medical Center, 11201 Benton Street, Loma Linda, CA 92357, USA.

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October 2008

Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice.

Authors:

Kristen E Govoni Jon E Wergedal Robert B Chadwick Apurva K Srivastava Subburaman Mohan

Am J Physiol Endocrinol Metab 2008 Nov 23;295(5):E1172-80. Epub 2008 Sep 23.

Jerry L. Pettis Memorial Veterans Affairs Medical Center, Loma Linda, California 92357, USA.

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November 2008

Bax deficiency in mice increases cartilage production during fracture repair through a mechanism involving increased chondrocyte proliferation without changes in apoptosis.

Authors:

Charles H Rundle Xiaoguang Wang Matilda H-C Sheng Jon E Wergedal K-H William Lau Subburaman Mohan

Bone 2008 Nov 29;43(5):880-8. Epub 2008 Jul 29.

Musculoskeletal Disease Center, Jerry L. Pettis Memorial Veterans Administration Medical Center (151), 11201 Benton Street, Loma Linda, CA 92357, USA.

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November 2008