Subash Babu

Subash Babu

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Subash Babu

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Plasma Proinflammatory Cytokines Are Markers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis.

Open Forum Infect Dis 2019 Jul 31;6(7):ofz257. Epub 2019 May 31.

National Institutes of Health, National Institute for Research in Tuberculosis, International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1093/ofid/ofz257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602384PMC
July 2019

Plasma levels of C-reactive protein, matrix metalloproteinase-7 and lipopolysaccharide-binding protein distinguish active pulmonary or extrapulmonary tuberculosis from uninfected controls in children.

Cytokine 2019 Jul 9;123:154773. Epub 2019 Jul 9.

Instituto Gonçalo Moniz, Salvador, Bahia, Brazil; Multinational Organization Network Sponsoring Translational and Epidemiological Research (MONSTER) Initiative, Fundação José Silveira, Salvador, Bahia, Brazil; Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil; Wellcome Trust Centre for Infectious Disease Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa; Universidade Salvador (UNIFACS), Laureate Universities, Salvador, Bahia, Brazil; Division of Infectious Diseases, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2019.154773DOI Listing
July 2019

Enhanced Mycobacterial Antigen-Induced Pro-Inflammatory Cytokine Production in Lymph Node Tuberculosis.

Am J Trop Med Hyg 2019 Jun;100(6):1401-1406

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.4269/ajtmh.18-0834DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553923PMC
June 2019

Elevated Systemic Levels of Eosinophil, Neutrophil, and Mast Cell Granular Proteins in Infection that Diminish following Treatment.

Front Immunol 2018 9;9:207. Epub 2018 Feb 9.

National Institutes of Health - National Institute of Research in Tuberculosis (ICMR) - International Center for Excellence in Research, Chennai, India.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811458PMC
April 2019

Coexistent Helminth Infection-Mediated Modulation of Chemokine Responses in Latent Tuberculosis.

J Immunol 2019 Mar 16;202(5):1494-1500. Epub 2019 Jan 16.

National Institutes of Health-National Institute for Research in Tuberculosis-International Center for Excellence in Research, Chennai, India 600031;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801190
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http://dx.doi.org/10.4049/jimmunol.1801190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382527PMC
March 2019

Helminth mediated modulation of the systemic and mycobacterial antigen - stimulated cytokine profiles in extra-pulmonary tuberculosis.

PLoS Negl Trop Dis 2019 03 21;13(3):e0007265. Epub 2019 Mar 21.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1371/journal.pntd.0007265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445485PMC
March 2019

Malnutrition is associated with diminished baseline and mycobacterial antigen - stimulated chemokine responses in latent tuberculosis infection.

J Infect 2018 Nov 17;77(5):410-416. Epub 2018 May 17.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340055PMC
November 2018

Diminished circulating plasma and elevated lymph node culture supernatant levels of IL-10 family cytokines in tuberculous lymphadenitis.

Cytokine 2018 Nov 2;111:511-517. Epub 2018 Jun 2.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.cyto.2018.05.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340908PMC
November 2018

Metabolic consequences of concomitant Strongyloides stercoralis infection in Type 2 diabetes mellitus.

Clin Infect Dis 2018 Nov 8. Epub 2018 Nov 8.

National Institute of Health-NIRT-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1093/cid/ciy935DOI Listing
November 2018

Altered Systemic Adipokine Levels in Pulmonary Tuberculosis and Changes following Treatment.

Am J Trop Med Hyg 2018 Oct;99(4):875-880

National Institutes of Health-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.4269/ajtmh.18-0206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159603PMC
October 2018

Modulation of Th1/Tc1 and Th17/Tc17 responses in pulmonary tuberculosis by IL-20 subfamily of cytokines.

Cytokine 2018 08 21;108:190-196. Epub 2018 Apr 21.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, United States.

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http://dx.doi.org/10.1016/j.cyto.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962435PMC
August 2018

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment.

BMC Infect Dis 2018 07 25;18(1):345. Epub 2018 Jul 25.

National Institutes of Health-NIH-NIRT-ICER, National Institute for Research in Tuberculosis, International Center for Excellence in Research, # 1 Mayor Sathyamoothy Road, Chetpet, Chennai, India.

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http://dx.doi.org/10.1186/s12879-018-3246-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060542PMC
July 2018

TLR-induced secretion of novel cytokine IL-27 is defective in newly diagnosed type-2 diabetic subjects.

Cytokine 2018 04 3;104:65-71. Epub 2017 Oct 3.

Dept of Genetics, Dr. ALM PG IBMS, University of Madras, Taramani, Chennai 600 113, India. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2017.09.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367208PMC
April 2018

Ononitol monohydrate enhances PRDM16 & UCP-1 expression, mitochondrial biogenesis and insulin sensitivity via STAT6 and LTBR in maturing adipocytes.

Biomed Pharmacother 2018 Mar;99:375-383

Adipogenesis and Immunobiology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, 11451, Saudi Arabia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322173647
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http://dx.doi.org/10.1016/j.biopha.2018.01.084DOI Listing
March 2018

Determining the Frequencies of Th9 Cells from Whole Blood.

Methods Mol Biol 2017 ;1585:83-92

National Institutes of Health - International Center for Excellence in Research, National Institute of Research in Tuberculosis (Formerly Tuberculosis Research Center), 1, Mayor Sathyamoorty Road, Chetpet, Chennai, India.

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http://link.springer.com/10.1007/978-1-4939-6877-0_7
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http://dx.doi.org/10.1007/978-1-4939-6877-0_7DOI Listing
February 2018

Modulation of iron status biomarkers in tuberculosis-diabetes co-morbidity.

Tuberculosis (Edinb) 2018 01 24;108:127-135. Epub 2017 Nov 24.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.tube.2017.11.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5846115PMC
January 2018

Biomarkers for Treatment Monitoring in Tuberculosis: A New Hope.

Authors:
Subash Babu

EBioMedicine 2017 12 3;26:13-14. Epub 2017 Nov 3.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832559PMC
December 2017

Comparison and functional characterisation of peripheral blood mononuclear cells isolated from filarial lymphoedema and endemic normals of a South Indian population.

Trop Med Int Health 2017 11 20;22(11):1414-1427. Epub 2017 Sep 20.

Department of Genetic Engineering, School of Biotechnology, Madurai Kamaraj University, Madurai, India.

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http://dx.doi.org/10.1111/tmi.12969DOI Listing
November 2017

Recombinant Brugia malayi pepsin inhibitor (rBm33) exploits host signaling events to regulate inflammatory responses associated with lymphatic filarial infections.

Microb Pathog 2017 Nov 20;112:195-208. Epub 2017 Sep 20.

Immunology Laboratory, Centre for Biotechnology, Anna University, Chennai, TN, India. Electronic address:

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http://dx.doi.org/10.1016/j.micpath.2017.09.015DOI Listing
November 2017

In vitro cytotoxic potential of friedelin in human MCF-7 breast cancer cell: Regulate early expression of Cdkn2a and pRb1, neutralize mdm2-p53 amalgamation and functional stabilization of p53.

Exp Toxicol Pathol 2017 Oct 12;69(8):630-636. Epub 2017 Jun 12.

Cancer Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.etp.2017.05.011DOI Listing
October 2017

Diminished plasma levels of common γ-chain cytokines in pulmonary tuberculosis and reversal following treatment.

PLoS One 2017 27;12(4):e0176495. Epub 2017 Apr 27.

National Institutes of Health-NIRT- International Center for Excellence in Research, Chennai, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0176495PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407607PMC
September 2017

Influence of diabetes mellitus on immunity to human tuberculosis.

Immunology 2017 09 29;152(1):13-24. Epub 2017 Jun 29.

National Institutes of Health-International Centre for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1111/imm.12762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543489PMC
September 2017

Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53.

Biomed Pharmacother 2017 Mar 6;87:388-396. Epub 2017 Jan 6.

Cancer Molecular Biology Research Lab, Department of Food Sceince and Nutrition, College of Food Science and Agriculture, King Saud University, Riyadh - 11451, Saudi Arabia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322163178
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http://dx.doi.org/10.1016/j.biopha.2016.12.091DOI Listing
March 2017

Reduced systemic and mycobacterial antigen-stimulated concentrations of IL-1β and IL-18 in tuberculous lymphadenitis.

Cytokine 2017 02 26;90:66-72. Epub 2016 Oct 26.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2016.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291808PMC
February 2017

Tuberculosis-diabetes co-morbidity is characterized by heightened systemic levels of circulating angiogenic factors.

J Infect 2017 01 4;74(1):10-21. Epub 2016 Oct 4.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; LPD, NIAID, NIH, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jinf.2016.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5164955PMC
January 2017

Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment.

Tuberculosis (Edinb) 2016 12 11;101:191-200. Epub 2016 Oct 11.

National Institutes of Health-NIRT- International Center for Excellence in Research, Chennai, India; LPD, NIAID, NIH, MD, USA.

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http://dx.doi.org/10.1016/j.tube.2016.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127284PMC
December 2016

High body mass index is associated with heightened systemic and mycobacterial antigen - Specific pro-inflammatory cytokines in latent tuberculosis.

Tuberculosis (Edinb) 2016 12 27;101:56-61. Epub 2016 Aug 27.

National Institutes of Health-International Center for Excellence in Research, Chennai, India. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2016.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340054PMC
December 2016

Nasopharyngeal aspirate & blood cytokine profile in infants hospitalized for respiratory syncytial virus bronchiolitis: A pilot study from south India.

Indian J Med Res 2016 Dec;144(6):929-931

Department of Pediatric Pulmonology, Kanchi Kamakoti CHILDS Trust Hospital & The CHILDS Trust Medical Research Foundation, Chennai, India.

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http://dx.doi.org/10.4103/ijmr.IJMR_1120_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433287PMC
December 2016

Zinc enhances CDKN2A pRb1 expression and regulates functional apoptosis via upregulation of p53 and p21 expression in human breast cancer MCF-7 cell.

Environ Toxicol Pharmacol 2016 Oct 2;47:19-27. Epub 2016 Aug 2.

Cancer Molecular Biology Research Lab, Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.etap.2016.08.002DOI Listing
October 2016

Effect of standard tuberculosis treatment on naive, memory and regulatory T-cell homeostasis in tuberculosis-diabetes co-morbidity.

Immunology 2016 09 26;149(1):87-97. Epub 2016 Jul 26.

National Institutes of Health - NIRT - International Centre for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1111/imm.12632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981606PMC
September 2016

Helminth-Tuberculosis Co-infection: An Immunologic Perspective.

Trends Immunol 2016 09 5;37(9):597-607. Epub 2016 Aug 5.

Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-0425, USA.

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http://dx.doi.org/10.1016/j.it.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003706PMC
September 2016

Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis.

PLoS One 2016 4;11(1):e0146318. Epub 2016 Jan 4.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146318PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699686PMC
July 2016

Chronic Endotoxemia in Subjects with Type-1 Diabetes Is Seen Much before the Onset of Microvascular Complications.

PLoS One 2015 14;10(9):e0137618. Epub 2015 Sep 14.

National Institutes of Health-International Center for Excellence in Research, National Institute for Research in Tuberculosis, Chennai, India.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137618PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4569180PMC
June 2016

Coincident helminth infection modulates systemic inflammation and immune activation in active pulmonary tuberculosis.

PLoS Negl Trop Dis 2014 6;8(11):e3289. Epub 2014 Nov 6.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0003289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222842PMC
May 2016

Erratum to "Aloe-Emodin Protects RIN-5F (Pancreatic β-cell) Cell from Glucotoxicity via Regulation of Pro-Inflammatory Cytokine and Downregulation of Bax and Caspase 3" [Biomol. Ther. 24 (2016) 49-56].

Biomol Ther (Seoul) 2016 May;24(3):346

Adipogenesis and Immunobiology Research Lab, Department of Food Sciences and Nutrition, College of Food Sciences and Agriculture, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.4062/biomolther.2016.346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859799PMC
May 2016

Coexistent Malnutrition Is Associated with Perturbations in Systemic and Antigen-Specific Cytokine Responses in Latent Tuberculosis Infection.

Clin Vaccine Immunol 2016 Apr 4;23(4):339-45. Epub 2016 Apr 4.

National Institutes of Health, National Institute for Research in Tuberculosis, International Center for Excellence in Research, Chennai, India

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http://dx.doi.org/10.1128/CVI.00009-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820505PMC
April 2016

Modulation of CD4+ and CD8+ T-Cell Function by Interleukin 19 and Interleukin 24 During Filarial Infections.

J Infect Dis 2016 Mar 20;213(5):811-5. Epub 2015 Oct 20.

National Institutes of Health (NIH)-National Institute for Research in Tuberculosis (NIRT)-International Center for Excellence in Research.

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https://academic.oup.com/jid/article-lookup/doi/10.1093/infd
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http://dx.doi.org/10.1093/infdis/jiv497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747619PMC
March 2016

Type 2 diabetes mellitus coincident with pulmonary or latent tuberculosis results in modulation of adipocytokines.

Cytokine 2016 Mar 6;79:74-81. Epub 2016 Jan 6.

National Institutes of Health-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1016/j.cyto.2015.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729624PMC
March 2016

Coincident diabetes mellitus modulates Th1-, Th2-, and Th17-cell responses in latent tuberculosis in an IL-10- and TGF-β-dependent manner.

Eur J Immunol 2016 Feb 19;46(2):390-9. Epub 2015 Nov 19.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1002/eji.201545973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340057PMC
February 2016

Systemic Cytokine Profiles in Strongyloides stercoralis Infection and Alterations following Treatment.

Infect Immun 2016 02 23;84(2):425-31. Epub 2015 Nov 23.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/IAI.01354-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730571PMC
February 2016

Coincident pre-diabetes is associated with dysregulated cytokine responses in pulmonary tuberculosis.

PLoS One 2014 13;9(11):e112108. Epub 2014 Nov 13.

National Institutes of Health-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112108PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230980PMC
January 2016

Violacein induces apoptosis in human breast cancer cells through up regulation of BAX, p53 and down regulation of MDM2.

Exp Toxicol Pathol 2016 Jan 28;68(1):89-97. Epub 2015 Oct 28.

Department of Veterinary Physiology, College of Veterinary Medicine, Chonbuk National University, Biosafety Research Institute, 664-14 1GA, Duckjin-Dong, Duckjin-Gu, Jeonju City, Jeollabuk-Do 561-756, South Korea.

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http://dx.doi.org/10.1016/j.etp.2015.10.002DOI Listing
January 2016

IL-10- and TGFβ-mediated Th9 Responses in a Human Helminth Infection.

PLoS Negl Trop Dis 2016 Jan 5;10(1):e0004317. Epub 2016 Jan 5.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1371/journal.pntd.0004317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701466PMC
January 2016

Aloe-Emodin Protects RIN-5F (Pancreatic β-cell) Cell from Glucotoxicity via Regulation of Pro-Inflammatory Cytokine and Downregulation of Bax and Caspase 3.

Biomol Ther (Seoul) 2016 Jan 1;24(1):49-56. Epub 2016 Jan 1.

Adipogenesis and Immunobiology Research Lab, Department of Food Sciences and Nutrition, College of Food Sciences and Agriculture, King Saud University, Riyadh 11451, Kingdom of Saudi Arabia.

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http://dx.doi.org/10.4062/biomolther.2015.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703352PMC
January 2016

Decreased frequencies of circulating CD4⁺ T follicular helper cells associated with diminished plasma IL-21 in active pulmonary tuberculosis.

PLoS One 2014 24;9(10):e111098. Epub 2014 Oct 24.

National Institutes of Health-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111098PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208798PMC
December 2015

Impaired toll-like receptor signalling in peripheral B cells from newly diagnosed type-2 diabetic subjects.

Cytokine 2015 Dec 8;76(2):253-259. Epub 2015 May 8.

AU-KBC Research Centre, MIT Campus of Anna University, Chennai 600 044, India; Dept of Genetics, Dr ALM PG IBMS, University of Madras, Taramani, Chennai, India. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10434666150016
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http://dx.doi.org/10.1016/j.cyto.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367209PMC
December 2015

Type 2 diabetes - Tuberculosis co-morbidity is associated with diminished circulating levels of IL-20 subfamily of cytokines.

Tuberculosis (Edinb) 2015 Dec 28;95(6):707-712. Epub 2015 Aug 28.

National Institutes of Health-NIRT-International Center for Excellence in Research, National Institute for Research in Tuberculosis, Chetpet, Chennai 600031, India. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666794PMC
December 2015

Modulation of pro- and anti-inflammatory cytokines in active and latent tuberculosis by coexistent Strongyloides stercoralis infection.

Tuberculosis (Edinb) 2015 Dec 8;95(6):822-828. Epub 2015 Oct 8.

National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14729792153011
Publisher Site
http://dx.doi.org/10.1016/j.tube.2015.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666738PMC
December 2015

Profiling leucocyte subsets in tuberculosis-diabetes co-morbidity.

Immunology 2015 Oct 6;146(2):243-50. Epub 2015 Jul 6.

National Institutes of Health-NIRT-International Centre for Excellence in Research, Chennai, India.

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http://dx.doi.org/10.1111/imm.12496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4582965PMC
October 2015

Increased IL-12 and decreased IL-33 serum levels are associated with increased Th1 and suppressed Th2 cytokine profile in patients with diabetic nephropathy (CURES-134).

Int J Clin Exp Pathol 2014 15;7(11):8008-15. Epub 2014 Oct 15.

AU-KBC Research Centre, MIT Campus of Anna University Chennai, India ; Department of Genetics, Dr.ALM.PG.IBMS, University of Madras Chennai, India.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270517PMC
September 2015

Parasite Antigen-Specific Regulation of Th1, Th2, and Th17 Responses in Strongyloides stercoralis Infection.

J Immunol 2015 Sep 22;195(5):2241-50. Epub 2015 Jul 22.

National Institutes of Health, International Center for Excellence in Research, Chennai 600031, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892

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http://dx.doi.org/10.4049/jimmunol.1500745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546867PMC
September 2015

IL-27 and TGFβ mediated expansion of Th1 and adaptive regulatory T cells expressing IL-10 correlates with bacterial burden and disease severity in pulmonary tuberculosis.

Immun Inflamm Dis 2015 Sep 18;3(3):289-99. Epub 2015 Jun 18.

National Institutes of Health-International Center for Excellence in Research Chennai, India ; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/iid3.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578527PMC
September 2015

Incidence of active pulmonary tuberculosis in patients with coincident filarial and/or intestinal helminth infections followed longitudinally in South India.

PLoS One 2014 11;9(4):e94603. Epub 2014 Apr 11.

Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094603PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3984271PMC
May 2015

Type 2 diabetes mellitus is associated with altered CD8(+) T and natural killer cell function in pulmonary tuberculosis.

Immunology 2015 Apr;144(4):677-86

National Institutes of Health - International Centre for Excellence in Research, Chennai, India; National Institute for Research in Tuberculosis, Chennai, India.

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http://dx.doi.org/10.1111/imm.12421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368174PMC
April 2015

Autophagy protects monocytes from Wolbachia heat shock protein 60-induced apoptosis and senescence.

PLoS Negl Trop Dis 2015 Apr 7;9(4):e0003675. Epub 2015 Apr 7.

Centre for Biotechnology, Anna University, Chennai, Tamil Nadu, India.

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http://dx.doi.org/10.1371/journal.pntd.0003675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388636PMC
April 2015

Hesperetin inhibit adipocyte differentiation and enhance Bax- and p21-mediated adipolysis in human mesenchymal stem cell adipogenesis.

J Biochem Mol Toxicol 2015 Mar 26;29(3):99-108. Epub 2014 Oct 26.

Molecular Biology Research Lab, Department of Food and Nutrition, College of Food and Agricultural Sciences, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.

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http://doi.wiley.com/10.1002/jbt.21672
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http://dx.doi.org/10.1002/jbt.21672DOI Listing
March 2015

Serum IL-9, IL-17, and TGF-β levels in subjects with diabetic kidney disease (CURES-134).

Cytokine 2015 Mar 23;72(1):109-12. Epub 2014 Dec 23.

AU-KBC Research Centre, MIT Campus of Anna University, Chennai, Tamil Nadu, India; Department of Genetics, Dr. A.L.M. PG IBMS, University of Madras, Chennai, Tamil Nadu, India. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2014.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367207PMC
March 2015

Treatment of W. bancrofti (Wb) in HIV/Wb coinfections in South India.

PLoS Negl Trop Dis 2015 Mar 20;9(3):e0003622. Epub 2015 Mar 20.

Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0003622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368731PMC
March 2015

Nymphayol increases glucose-stimulated insulin secretion by RIN-5F cells and GLUT4-mediated insulin sensitization in type 2 diabetic rat liver.

Chem Biol Interact 2015 Jan 12;226:72-81. Epub 2014 Dec 12.

Department of Food Sciences and Nutrition, College of Food Sciences and Agriculture, King Saud University, P.O. Box 2460, Riyadh 11451, Saudi Arabia. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.12.011DOI Listing
January 2015

Interleukin-10- and transforming growth factor β-independent regulation of CD8⁺ T cells expressing type 1 and type 2 cytokines in human lymphatic filariasis.

Clin Vaccine Immunol 2014 Dec 24;21(12):1620-7. Epub 2014 Sep 24.

National Institutes of Health-International Center for Excellence in Research, Chennai, India Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/CVI.00598-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248783PMC
December 2014

Gastroprotective effect of nymphayol isolated from Nymphaea stellata (Willd.) flowers: contribution of antioxidant, anti-inflammatory and anti-apoptotic activities.

Chem Biol Interact 2014 Dec 5;224:157-63. Epub 2014 Oct 5.

Department of Veterinary Physiology, College of Veterinary Medicine, Chonbuk National University, Biosafety Research Institute, 664-14, 1GA, Duckjin-Dong, Duckjin-Gu, Jeonju City, Jeollabuk-Do 561-756, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2014.09.020DOI Listing
December 2014

Diminished systemic and antigen-specific type 1, type 17, and other proinflammatory cytokines in diabetic and prediabetic individuals with latent Mycobacterium tuberculosis infection.

J Infect Dis 2014 Nov 6;210(10):1670-8. Epub 2014 Jun 6.

National Institutes of Health-International Center for Excellence in Research Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1093/infdis/jiu329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215076PMC
November 2014

Human monocyte subsets at homeostasis and their perturbation in numbers and function in filarial infection.

Infect Immun 2014 Nov 11;82(11):4438-46. Epub 2014 Aug 11.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.

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http://iai.asm.org/lookup/doi/10.1128/IAI.01973-14
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http://dx.doi.org/10.1128/IAI.01973-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249311PMC
November 2014

Parasite-antigen driven expansion of IL-5(-) and IL-5(+) Th2 human subpopulations in lymphatic filariasis and their differential dependence on IL-10 and TGFβ.

PLoS Negl Trop Dis 2014 30;8(1):e2658. Epub 2014 Jan 30.

National Institutes of Health-International Center for Excellence in Research, Chennai, India ; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.plos.org/10.1371/journal.pntd.0002658
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http://dx.doi.org/10.1371/journal.pntd.0002658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907332PMC
September 2014

Altered CD8(+) T cell frequency and function in tuberculous lymphadenitis.

Tuberculosis (Edinb) 2014 Sep 1;94(5):482-93. Epub 2014 Jul 1.

National Institutes of Health-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.tube.2014.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171352PMC
September 2014

Helminth infections coincident with active pulmonary tuberculosis inhibit mono- and multifunctional CD4+ and CD8+ T cell responses in a process dependent on IL-10.

PLoS Pathog 2014 Sep 11;10(9):e1004375. Epub 2014 Sep 11.

ICER Department, National Institutes of Health-NIRT-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161445PMC
http://dx.doi.org/10.1371/journal.ppat.1004375DOI Listing
September 2014

Interleukin 1 (IL-1)- and IL-23-mediated expansion of filarial antigen-specific Th17 and Th22 cells in filarial lymphedema.

Clin Vaccine Immunol 2014 Jul 7;21(7):960-5. Epub 2014 May 7.

National Institutes of Health, International Center for Excellence in Research, Chennai, India Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/CVI.00257-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097448PMC
July 2014

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk.

Nature 2014 Jul 25;511(7507):99-103. Epub 2014 Jun 25.

Immunobiology Section, Laboratory of Parasitic Diseases (LPD), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1038/nature13489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809146PMC
July 2014

Heightened plasma levels of heme oxygenase-1 and tissue inhibitor of metalloproteinase-4 as well as elevated peripheral neutrophil counts are associated with TB-diabetes comorbidity.

Chest 2014 Jun;145(6):1244-1254

Immunobiology Section, Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, MD; National Institutes of Health, International Center for Excellence in Research, Chennai, India.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692153479
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http://dx.doi.org/10.1378/chest.13-1799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042512PMC
June 2014

Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis.

PLoS Negl Trop Dis 2014 Apr 3;8(4):e2762. Epub 2014 Apr 3.

National Institutes of Health-International Center for Excellence in Research, Chennai, India; Laboratory of Parasitic Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0002762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974669PMC
April 2014

Increased Th1 and suppressed Th2 serum cytokine levels in subjects with diabetic coronary artery disease.

Cardiovasc Diabetol 2014 Jan 3;13. Epub 2014 Jan 3.

AU-KBC Research Centre, MIT Campus of Anna University, Chennai 600 044, India.

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http://dx.doi.org/10.1186/1475-2840-13-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893369PMC
January 2014

Beneficial Antioxidative and Antiperoxidative Effect of Cinnamaldehyde Protect Streptozotocin-Induced Pancreatic β-Cells Damage in Wistar Rats.

Biomol Ther (Seoul) 2014 Jan;22(1):47-54

Division of Ethnopharmacology, Entomology Research Institute, Loyola College, Chennai 600 034, Tamil Nadu, India.

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http://dx.doi.org/10.4062/biomolther.2013.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936432PMC
January 2014