Stuart P McElroy

Stuart P McElroy

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Stuart P McElroy

Stuart P McElroy

Publications by authors named "Stuart P McElroy"

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18Publications

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Burkholderia pseudomallei d-alanine-d-alanine ligase; detailed characterisation and assessment of a potential antibiotic drug target.

FEBS J 2019 Nov 16;286(22):4509-4524. Epub 2019 Jul 16.

Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, UK.

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http://dx.doi.org/10.1111/febs.14976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899670PMC
November 2019

Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective.

SLAS Discov 2018 03;23(3):225-241

1 European Screening Centre Newhouse, Biocity Scotland, University of Dundee, Newhouse, UK.

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http://dx.doi.org/10.1177/2472555217744728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824829PMC
March 2018

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines.

Cell Chem Biol 2017 Aug 3;24(8):981-992.e4. Epub 2017 Aug 3.

Centre for Gene Regulation & Expression, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2017.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563080PMC
August 2017

In Vitro Assay Development and HTS of Small-Molecule Human ABAD/17β-HSD10 Inhibitors as Therapeutics in Alzheimer's Disease.

SLAS Discov 2017 07 17;22(6):676-685. Epub 2017 Mar 17.

1 School of Biology, University of St. Andrews, Medical and Biological Sciences Building, North Haugh, St. Andrews, Fife, UK.

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http://dx.doi.org/10.1177/2472555217697964DOI Listing
July 2017

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1.

Sci Rep 2017 03 22;7(1):294. Epub 2017 Mar 22.

Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University, Edinburgh Campus, Edinburgh, EH14 4AS, UK.

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http://dx.doi.org/10.1038/s41598-017-00455-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428521PMC
March 2017

The SULSA Assay Development Fund: accelerating translation of new biology from academia to pharma.

Drug Discov Today 2017 02 5;22(2):199-203. Epub 2016 Oct 5.

NPSC Edinburgh, University of Edinburgh, Room 145/6 - Peter Wilson Building, The King's Buildings, Edinburgh EH9 3FH, UK.

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http://dx.doi.org/10.1016/j.drudis.2016.09.028DOI Listing
February 2017

Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells.

Biochim Biophys Acta 2015 Jul 23;1853(7):1749-58. Epub 2015 Apr 23.

Institute of Molecular, Cellular and Systems Biology, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2015.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547084PMC
July 2015

A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays.

PLoS Biol 2013 25;11(6):e1001593. Epub 2013 Jun 25.

Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, James Black Centre, Dow Street, University of Dundee, Dundee, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1001593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692445PMC
January 2014

Regulation of store-operated Ca2+ entry in pulmonary artery smooth muscle cells.

Cell Calcium 2009 Aug 1;46(2):99-106. Epub 2009 Jul 1.

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 27 Taylor Street, Glasgow G4 0NR, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S014341600900089
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http://dx.doi.org/10.1016/j.ceca.2009.05.006DOI Listing
August 2009

Pharmacological profile of store-operated Ca(2+) entry in intrapulmonary artery smooth muscle cells.

Eur J Pharmacol 2008 Apr 26;584(1):10-20. Epub 2008 Jan 26.

Division of Physiology and Pharmacology, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0NR, United Kingdom.

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http://dx.doi.org/10.1016/j.ejphar.2008.01.018DOI Listing
April 2008

Antiinflammatory, gastrosparing, and antiplatelet properties of new NO-donor esters of aspirin.

J Med Chem 2003 Feb;46(5):747-54

Dipartimento di Scienza e Tecnologia del Farmaco, Università degli Studi di Torino, via Pietro Giuria 9, 10125 Torino, Italy.

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http://dx.doi.org/10.1021/jm020969tDOI Listing
February 2003