Publications by authors named "Stuart Maudsley"

100Publications

Profiling of the Peripheral Blood Mononuclear Cell Proteome in Schizophrenia and Mood Disorders for the Discovery of Discriminatory Biomarkers: A Proof-of-Concept Study.

Neuropsychobiology 2020 11;79(4-5):324-334. Epub 2020 May 11.

Scientific Initiative for Neuropsychiatric and Psychopharmacological Studies (SINAPS), Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1159/000507631DOI Listing
May 2020

G Protein-Coupled Receptor Systems and Their Role in Cellular Senescence.

Comput Struct Biotechnol J 2019 23;17:1265-1277. Epub 2019 Aug 23.

Receptor Biology Lab, University of Antwerp, 2610 Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.csbj.2019.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944711PMC
August 2019

Multisystem proteinopathy due to a homozygous p.Arg159His mutation: A tale of the unexpected.

Neurology 2020 02 17;94(8):e785-e796. Epub 2019 Dec 17.

From the Neurogenetics Group (W.D.R., P.D.J., J.B.), Laboratory of Neuromuscular Pathology (W.D.R., P.D.J., J.B.), Institute Born-Bunge, Neuromics Support Facility (A.A.), VIB-UAntwerp Center for Molecular Neurology, and Receptor Biology Lab (S.M.), Department of Biomedical Sciences, University of Antwerp; Neuromuscular Reference Centre (W.D.R., P.D.J., J.B.), Department of Neurology, Antwerp University Hospital, Belgium; Institute of Neuropathology (C.S.C., R.S.), University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen; Centre for Biochemistry (C.S.C., L.E.), Institute of Biochemistry I, and Center for Physiology and Pathophysiology (C.S.C.), Institute of Vegetative Physiology, Medical Faculty, University of Cologne, Germany; Griffith Institute for Drug Discovery (A.H), Griffith University, Nathan, Brisbane, Queensland; Department of Veterinary Biosciences (A.H.), Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Victoria, Australia; John Walton Muscular Dystrophy Research Centre (K.J., A.T., V.S.), Institute of Genetic Medicine, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle-Upon-Tyne, UK; and Laboratory for Neuropathology (J.L.D.B.), Division of Neurology, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1212/WNL.0000000000008763DOI Listing
February 2020

High-dimensionality Data Analysis of Pharmacological Systems Associated with Complex Diseases.

Pharmacol Rev 2020 01;72(1):191-217

Receptor Biology Laboratory, Department of Biomedical Research (J.O.H., J.v.G., H.L., S.M.) and Faculty of Pharmacy, Biomedical and Veterinary Sciences (J.O.H., J.v.G., H.L., B.M., S.M.), University of Antwerp, Antwerp, Belgium

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http://dx.doi.org/10.1124/pr.119.017921DOI Listing
January 2020

The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage.

Aging (Albany NY) 2019 12 3;11(23):11268-11313. Epub 2019 Dec 3.

Receptor Biology Lab, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.18632/aging.102528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932917PMC
December 2019

Multidimensional informatic deconvolution defines gender-specific roles of hypothalamic GIT2 in aging trajectories.

Mech Ageing Dev 2019 12 28;184:111150. Epub 2019 Sep 28.

Receptor Biology Lab, Department of Biomedical Sciences, University of Antwerp, 2610, Wilrijk, Belgium; Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Biomedical Research Center, 251 Bayview Boulevard, Baltimore, MD, 21224, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2019.111150DOI Listing
December 2019

Sclerostin as Regulatory Molecule in Vascular Media Calcification and the Bone-Vascular Axis.

Toxins (Basel) 2019 07 21;11(7). Epub 2019 Jul 21.

Laboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, 2610 Wilrijk, Belgium.

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http://dx.doi.org/10.3390/toxins11070428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669501PMC
July 2019

Enhanced Molecular Appreciation of Psychiatric Disorders Through High-Dimensionality Data Acquisition and Analytics.

Methods Mol Biol 2019 ;2011:671-723

Receptor Biology Lab, Department of Biomedical Research, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-9554-7_39DOI Listing
March 2020

GRK5 - A Functional Bridge Between Cardiovascular and Neurodegenerative Disorders.

Front Pharmacol 2018 17;9:1484. Epub 2018 Dec 17.

Department of Biomedical Science, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fphar.2018.01484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304357PMC
December 2018

G Protein-Coupled Receptor Systems as Crucial Regulators of DNA Damage Response Processes.

Int J Mol Sci 2018 Sep 26;19(10). Epub 2018 Sep 26.

Department of Biomedical Sciences, University of Antwerp, 2610 Antwerp, Belgium.

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http://www.mdpi.com/1422-0067/19/10/2919
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http://dx.doi.org/10.3390/ijms19102919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213947PMC
September 2018

GIT2-A keystone in ageing and age-related disease.

Ageing Res Rev 2018 May 13;43:46-63. Epub 2018 Feb 13.

Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium; Translational Neurobiology Group, Center of Molecular Neurology, VIB, Antwerp, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2018.02.002DOI Listing
May 2018

Translating in vitro ligand bias into in vivo efficacy.

Cell Signal 2018 01 7;41:46-55. Epub 2017 May 7.

Division of Endocrinology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.cellsig.2017.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675828PMC
January 2018

Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2.

Cell Rep 2016 05 21;15(5):926-934. Epub 2016 Apr 21.

Laboratory of Genetics, National Institute on Aging-Intramural Research Program, NIH, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856555PMC
May 2016

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

Front Endocrinol (Lausanne) 2015 18;6:191. Epub 2016 Jan 18.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA; Translational Neurobiology Group, VIB Department of Molecular Genetics, University of Antwerp, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.3389/fendo.2015.00191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4716144PMC
February 2016

Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder.

Front Physiol 2015 24;6:324. Epub 2015 Nov 24.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health Baltimore, MD, USA ; Translational Neurobiology Group, VIB Department of Molecular Genetics, University of Antwerp Antwerp, Belgium ; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp Antwerpen, Belgium.

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http://dx.doi.org/10.3389/fphys.2015.00324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656818PMC
December 2015

Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus.

Cell Rep 2015 Nov 29;13(6):1073-1080. Epub 2015 Oct 29.

Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Section on Growth and Obesity, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), NIH, Bethesda, MD 20892, USA; Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN 38163, USA; Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN 38103, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(15)01107-9.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471501107
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http://dx.doi.org/10.1016/j.celrep.2015.09.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644471PMC
November 2015

Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.

Mol Pharmacol 2015 Sep 1;88(3):579-88. Epub 2015 Jul 1.

Departments of Medicine and Biochemistry & Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.); Translational Neurobiology Group, VIB Department of Molecular Genetics, Laboratory of Neurogenetics-Institute Born-Bunge, University of Antwerp, Belgium (S.M.); and Department of Molecular Therapeutics and Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida (L.M.B.).

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http://dx.doi.org/10.1124/mol.115.099630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551052PMC
September 2015

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Mol Pharmacol 2015 Apr 30;87(4):706-17. Epub 2015 Jan 30.

National Institutes of Health, National Institute on Aging, Baltimore, Maryland (S.M., B.M., S.P., K.G.B., W.H.W., Y.Z., E.L.); Department of Medicine, Duke University Medical Center, Durham, North Carolina (D.G.-P.); National Institutes of Health, Center for Information Technology, Bethesda, Maryland (H.C., C.J.); Department of Medicine and Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina (L.M.L.); and Ralph H. Johnson Veterans Affairs Medical Center, Charleston, South Carolina (L.M.L.).

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http://molpharm.aspetjournals.org/content/87/4/706.full.pdf
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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.114.09
Publisher Site
http://dx.doi.org/10.1124/mol.114.095224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366796PMC
April 2015

Nuclear GIT2 is an ATM substrate and promotes DNA repair.

Mol Cell Biol 2015 Apr 20;35(7):1081-96. Epub 2015 Jan 20.

Receptor Pharmacology Unit, National Institute on Aging, Baltimore, Maryland, USA VIB Department of Molecular Genetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium

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http://dx.doi.org/10.1128/MCB.01432-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355538PMC
April 2015

Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.

J Biol Chem 2015 Jan 11;290(5):2728-43. Epub 2014 Dec 11.

Receptor Pharmacology Unit, the VIB Department of Molecular Genetics, Institute Born-Bunge Laboratory of Neurogenetics, University of Antwerp, 2000 Antwerp, Belgium

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http://dx.doi.org/10.1074/jbc.M114.588608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317004PMC
January 2015

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.

J Exp Med 2014 Nov 3;211(12):2373-83. Epub 2014 Nov 3.

Department of Dermatology, Department of Pathology and Laboratory Medicine, Department of Radiation Oncology, and Department of Dermatology and Internal Medicine, University of California, Davis, Sacramento, CA 95817

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http://dx.doi.org/10.1084/jem.20140116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4235633PMC
November 2014

Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor System.

Front Endocrinol (Lausanne) 2014 1;5:142. Epub 2014 Sep 1.

Translational Neurobiology Group, VIB Department of Molecular Genetics, University of Antwerp , Antwerp , Belgium.

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http://dx.doi.org/10.3389/fendo.2014.00142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150252PMC
September 2014

The effects of aging on the BTBR mouse model of autism spectrum disorder.

Front Aging Neurosci 2014 1;6:225. Epub 2014 Sep 1.

Receptor Pharmacology Unit, Laboratory of Neurosciences, National Institute on Aging Baltimore, MD, USA ; VIB-Department of Molecular Genetics, University of Antwerp Antwerp, Belgium.

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http://dx.doi.org/10.3389/fnagi.2014.00225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150363PMC
September 2014

Higher TNF-α, IGF-1, and Leptin Levels are Found in Tasters than Non-Tasters.

Front Endocrinol (Lausanne) 2014 29;5:125. Epub 2014 Jul 29.

Metabolism Unit, National Institute on Aging, National Institutes of Health , Baltimore, MD , USA.

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http://dx.doi.org/10.3389/fendo.2014.00125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4114300PMC
August 2014

What is the role of metabolic hormones in taste buds of the tongue.

Front Horm Res 2014 7;42:134-46. Epub 2014 Apr 7.

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Md., USA.

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http://dx.doi.org/10.1159/000358322DOI Listing
December 2014

The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases.

Am J Alzheimers Dis (Columbia) 2013 ;1(1)

Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224.

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http://dx.doi.org/10.7726/ajad.2013.1003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817016PMC
January 2013

Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism.

Brain Behav Immun 2014 Feb 18;36:90-100. Epub 2013 Oct 18.

Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD 21224, USA; School of Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.bbi.2013.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947180PMC
February 2014

Altered lipid and salt taste responsivity in ghrelin and GOAT null mice.

PLoS One 2013 4;8(10):e76553. Epub 2013 Oct 4.

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790684PMC
May 2014

Plurigon: three dimensional visualization and classification of high-dimensionality data.

Front Physiol 2013 22;4:190. Epub 2013 Jul 22.

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fphys.2013.00190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717481PMC
July 2013

Systems analysis of arrestin pathway functions.

Prog Mol Biol Transl Sci 2013 ;118:431-67

Receptor Pharmacology Unit, National Institute on Aging, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1016/B978-0-12-394440-5.00017-6DOI Listing
March 2014

Textrous!: extracting semantic textual meaning from gene sets.

PLoS One 2013 30;8(4):e62665. Epub 2013 Apr 30.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0062665PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639949PMC
November 2013

BRET Biosensor Analysis of Receptor Tyrosine Kinase Functionality.

Front Endocrinol (Lausanne) 2013 9;4:46. Epub 2013 Apr 9.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fendo.2013.00046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620488PMC
April 2013

Effective use of latent semantic indexing and computational linguistics in biological and biomedical applications.

Front Physiol 2013 30;4. Epub 2013 Jan 30.

Laboratory of Neuroscience, Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fphys.2013.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3558626PMC
February 2013

β-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo.

Mol Endocrinol 2013 Feb 11;27(2):296-314. Epub 2013 Jan 11.

Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1210/me.2012-1091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683806PMC
February 2013

VennPlex--a novel Venn diagram program for comparing and visualizing datasets with differentially regulated datapoints.

PLoS One 2013 7;8(1):e53388. Epub 2013 Jan 7.

Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0053388PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538763PMC
July 2013

Pancreas++: automated quantification of pancreatic islet cells in microscopy images.

Front Physiol 2012 3;3:482. Epub 2013 Jan 3.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health Baltimore, MD, USA.

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http://dx.doi.org/10.3389/fphys.2012.00482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3535421PMC
January 2013

Classification of Alzheimer Diagnosis from ADNI Plasma Biomarker Data.

ACM Conf Bioinform Comput Biol Biomed Inform (2013) 2013;2013:569

Division of Computational Bioscience, Center for Information Technology, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1145/2506583.2506637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295502PMC
January 2013

Altered hypothalamic protein expression in a rat model of Huntington's disease.

PLoS One 2012 18;7(10):e47240. Epub 2012 Oct 18.

Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475691PMC
April 2013

Aging and bone health in individuals with developmental disabilities.

Int J Endocrinol 2012 22;2012:469235. Epub 2012 Jul 22.

Metabolism Unit, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1155/2012/469235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408668PMC
August 2012

Central role of the EGF receptor in neurometabolic aging.

Int J Endocrinol 2012 17;2012:739428. Epub 2012 Jun 17.

Receptor Pharmacology Unit, National Institute on Aging, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1155/2012/739428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382947PMC
August 2012

Precursor ion exclusion for enhanced identification of plasma biomarkers.

Proteomics Clin Appl 2012 Jun;6(5-6):304-8

Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1002/prca.201100107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916817PMC
June 2012

GIT2 acts as a potential keystone protein in functional hypothalamic networks associated with age-related phenotypic changes in rats.

PLoS One 2012 14;7(5):e36975. Epub 2012 May 14.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Biomedical Research Center, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036975PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351446PMC
October 2012

VENNTURE--a novel Venn diagram investigational tool for multiple pharmacological dataset analysis.

PLoS One 2012 14;7(5):e36911. Epub 2012 May 14.

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036911PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351456PMC
October 2012

Effective correction of experimental errors in quantitative proteomics using stable isotope labeling by amino acids in cell culture (SILAC).

J Proteomics 2012 Jun 7;75(12):3720-32. Epub 2012 May 7.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.jprot.2012.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394155PMC
June 2012

Growth inhibition by miR-519 via multiple p21-inducing pathways.

Mol Cell Biol 2012 Jul 30;32(13):2530-48. Epub 2012 Apr 30.

Laboratory of Molecular Biology and Immunology, Research Resources Branch, National Institute on Aging, NIH, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1128/MCB.00510-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434494PMC
July 2012

Stromal factors SDF1α, sFRP1, and VEGFD induce dopaminergic neuron differentiation of human pluripotent stem cells.

J Neurosci Res 2012 Jul 26;90(7):1367-81. Epub 2012 Apr 26.

National Institute on Aging Intramural Research Program, National Institutes of Health, Laboratory of Neurosciences, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1002/jnr.23064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350575PMC
July 2012

Discovery- and target-based protein quantification using iTRAQ and pulsed Q collision induced dissociation (PQD).

J Proteomics 2012 Apr 3;75(8):2480-7. Epub 2012 Mar 3.

Metabolism Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.jprot.2012.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321122PMC
April 2012

Therapeutic targeting of the endoplasmic reticulum in Alzheimer's disease.

Curr Alzheimer Res 2012 Jan;9(1):110-9

Receptor Pharmacology Unit, National Institute on Aging, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4682200PMC
http://dx.doi.org/10.2174/156720512799015055DOI Listing
January 2012

Anti-inflammatory effects of physical activity in relationship to improved cognitive status in humans and mouse models of Alzheimer's disease.

Curr Alzheimer Res 2012 Jan;9(1):86-92

Department of Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445413PMC
http://dx.doi.org/10.2174/156720512799015019DOI Listing
January 2012

Metabolic dysfunction in Alzheimer's disease and related neurodegenerative disorders.

Curr Alzheimer Res 2012 Jan;9(1):5-17

Metabolism Unit, National Institute on Aging, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097094PMC
http://dx.doi.org/10.2174/156720512799015064DOI Listing
January 2012

Age-related changes in mouse taste bud morphology, hormone expression, and taste responsivity.

J Gerontol A Biol Sci Med Sci 2012 Apr 4;67(4):336-44. Epub 2011 Nov 4.

Laboratory of Clinical Investigation, Diabetes Section, National Institute on Aging, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1093/gerona/glr192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410661PMC
April 2012

Identification of proteins and phosphoproteins using pulsed Q collision induced dissociation (PQD).

J Am Soc Mass Spectrom 2011 Oct 15;22(10):1753-62. Epub 2011 Jul 15.

Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1007/s13361-011-0197-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3183836PMC
October 2011

To be or not to be--obese.

Endocrinology 2011 Oct;152(10):3592-6

Intramural Research Program/National Institute on Aging/National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1210/en.2011-1615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176656PMC
October 2011

The effects of the ketogenic diet on behavior and cognition.

Epilepsy Res 2012 Jul 27;100(3):304-9. Epub 2011 Aug 27.

Queen Silvia Children's Hospital, Sahlgrenska University, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.eplepsyres.2011.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112040PMC
July 2012

Bioinformatic approaches to metabolic pathways analysis.

Methods Mol Biol 2011 ;756:99-130

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/978-1-61779-160-4_5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698828PMC
December 2011

Cortical gene transcription response patterns to water maze training in aged mice.

BMC Neurosci 2011 Jun 29;12:63. Epub 2011 Jun 29.

Receptor Pharmacology Unit, National Institute on Aging, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1186/1471-2202-12-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142531PMC
June 2011

Rapid and enhanced proteolytic digestion using electric-field-oriented enzyme reactor.

J Proteomics 2011 Jun 19;74(7):1030-5. Epub 2011 Feb 19.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, Biomedical Research Center, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.jprot.2011.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102135PMC
June 2011

Repetitive peroxide exposure reveals pleiotropic mitogen-activated protein kinase signaling mechanisms.

J Signal Transduct 2011 19;2011:636951. Epub 2010 Dec 19.

Receptor Pharmacology Unit, Laboratory of Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1155/2011/636951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023409PMC
August 2012

Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.

PLoS One 2010 Dec 17;5(12):e14352. Epub 2010 Dec 17.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003681PMC
December 2010

Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease.

Int J Alzheimers Dis 2010 Dec 2;2010:604792. Epub 2010 Dec 2.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Suite 100, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.4061/2010/604792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997345PMC
December 2010

Discontinuous pH gradient-mediated separation of TiO2-enriched phosphopeptides.

Anal Biochem 2011 Feb 12;409(1):81-8. Epub 2010 Oct 12.

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1016/j.ab.2010.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002755PMC
February 2011

New frontiers in G protein-coupled receptor regulation of neurological disorders.

Authors:
Stuart Maudsley

CNS Neurol Disord Drug Targets 2010 Nov;9(5):525

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http://dx.doi.org/10.2174/187152710793361540DOI Listing
November 2010

Ghrelin receptor signaling: a promising therapeutic target for metabolic syndrome and cognitive dysfunction.

CNS Neurol Disord Drug Targets 2010 Nov;9(5):557-63

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967656PMC
http://dx.doi.org/10.2174/187152710793361513DOI Listing
November 2010

The mammalian tachykinin ligand-receptor system: an emerging target for central neurological disorders.

CNS Neurol Disord Drug Targets 2010 Nov;9(5):627-35

Receptor Pharmacology Unit, Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967650PMC
http://dx.doi.org/10.2174/187152710793361504DOI Listing
November 2010

Gonadotropin-releasing hormone receptor system: modulatory role in aging and neurodegeneration.

CNS Neurol Disord Drug Targets 2010 Nov;9(5):651-60

Receptor Pharmacology Unit, National Institute on Aging, National Institutes of Health, Biomedical Research Center, Baltimore MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967575PMC
http://dx.doi.org/10.2174/187152710793361559DOI Listing
November 2010

Therapeutic potential of vasoactive intestinal peptide and its receptors in neurological disorders.

CNS Neurol Disord Drug Targets 2010 Nov;9(5):661-6

Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD 21224, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967653PMC
http://dx.doi.org/10.2174/187152710793361595DOI Listing
November 2010

"Control" laboratory rodents are metabolically morbid: why it matters.

Proc Natl Acad Sci U S A 2010 Apr 1;107(14):6127-33. Epub 2010 Mar 1.

Metabolism Unit, Laboratory of Clinical Investigation, Laboratory of Neurosciences, National Institute on Aging Intramural Research Program, Baltimore, MD 21224, USA.

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http://dx.doi.org/10.1073/pnas.0912955107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852022PMC
April 2010