Stuart M Pickering-Brown

Stuart M Pickering-Brown

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Stuart M Pickering-Brown

Stuart M Pickering-Brown

Publications by authors named "Stuart M Pickering-Brown"

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37Publications

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CRISPR/Cas9 does not facilitate stable expression of long C9orf72 dipeptides in mice.

Neurobiol Aging 2019 Dec 24;84:235.e1-235.e8. Epub 2019 Sep 24.

Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.09.010DOI Listing
December 2019

Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model.

Hum Mol Genet 2018 05;27(10):1754-1762

Department of Neurosciences, Research Center of the University of Montréal Hospital Center (CRCHUM), Université de Montréal, Montréal, QC H2X 0A9, Canada.

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http://dx.doi.org/10.1093/hmg/ddy083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932562PMC
May 2018

Modelling C9orf72 dipeptide repeat proteins of a physiologically relevant size.

Hum Mol Genet 2016 12;25(23):5069-5082

Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, AV Hill Building, Oxford Road, Manchester, UK.

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http://dx.doi.org/10.1093/hmg/ddw327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886041PMC
December 2016

Identification of biological pathways regulated by PGRN and GRN peptide treatments using transcriptome analysis.

Eur J Neurosci 2016 09 9;44(5):2214-25. Epub 2016 Jul 9.

Institute of Brain Behaviour and Mental Health, University of Manchester, AV Hill Building, Ackers Street, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1111/ejn.13297DOI Listing
September 2016

p62/SQSTM1 analysis in frontotemporal lobar degeneration.

Neurobiol Aging 2015 Mar 18;36(3):1603.e5-9. Epub 2014 Oct 18.

Faculty of Medical and Human Sciences, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.08.035DOI Listing
March 2015

Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration.

Neurobiol Aging 2015 Mar 18;36(3):1603.e1-4. Epub 2014 Oct 18.

Faculty of Human and Medical Sciences, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester, UK; Cerebral Function Unit, Department of Neurology, Greater Manchester Neuroscience Centre, Salford Royal Foundation Trust, Salford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504979PMC
March 2015

Small deletion in C9orf72 hides a proportion of expansion carriers in FTLD.

Neurobiol Aging 2015 Mar 12;36(3):1601.e1-5. Epub 2014 Dec 12.

Faculty of Human and Medical Sciences, Institute of Brain Behaviour and Mental Health, University of Manchester, Manchester, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353501PMC
March 2015

Pathogenesis/genetics of frontotemporal dementia and how it relates to ALS.

Exp Neurol 2014 Dec 8;262 Pt B:84-90. Epub 2014 Jun 8.

Institute of Brain, Behaviour and Mental Health, University of Manchester, Oxford Road, Manchester, M13 9PT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2014.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221591PMC
December 2014

Analysis of the hexanucleotide repeat in C9ORF72 in Alzheimer's disease.

Neurobiol Aging 2012 Aug 10;33(8):1846.e5-6. Epub 2012 Mar 10.

Mental Health and Neurodegeneration Research Group, Faculty of Human and Medical Sciences, University of Manchester, AV Hill Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.01.109DOI Listing
August 2012

Analysis of optineurin in frontotemporal lobar degeneration.

Neurobiol Aging 2012 Feb 12;33(2):425.e1-2. Epub 2010 Nov 12.

Neurodegeneration and Mental Health Research Group, Faculty of Human and Medical Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2010.10.002DOI Listing
February 2012

No association of PGRN 3'UTR rs5848 in frontotemporal lobar degeneration.

Neurobiol Aging 2011 Apr 14;32(4):754-5. Epub 2009 May 14.

Clinical Neurosciences Research Group, Faculty of Human and Medical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1016/j.neurobiolaging.2009.04.009DOI Listing
April 2011

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

Authors:
Vivianna M Van Deerlin Patrick M A Sleiman Maria Martinez-Lage Alice Chen-Plotkin Li-San Wang Neill R Graff-Radford Dennis W Dickson Rosa Rademakers Bradley F Boeve Murray Grossman Steven E Arnold David M A Mann Stuart M Pickering-Brown Harro Seelaar Peter Heutink John C van Swieten Jill R Murrell Bernardino Ghetti Salvatore Spina Jordan Grafman John Hodges Maria Grazia Spillantini Sid Gilman Andrew P Lieberman Jeffrey A Kaye Randall L Woltjer Eileen H Bigio Marsel Mesulam Safa Al-Sarraj Claire Troakes Roger N Rosenberg Charles L White Isidro Ferrer Albert Lladó Manuela Neumann Hans A Kretzschmar Christine Marie Hulette Kathleen A Welsh-Bohmer Bruce L Miller Ainhoa Alzualde Adolfo Lopez de Munain Ann C McKee Marla Gearing Allan I Levey James J Lah John Hardy Jonathan D Rohrer Tammaryn Lashley Ian R A Mackenzie Howard H Feldman Ronald L Hamilton Steven T Dekosky Julie van der Zee Samir Kumar-Singh Christine Van Broeckhoven Richard Mayeux Jean Paul G Vonsattel Juan C Troncoso Jillian J Kril John B J Kwok Glenda M Halliday Thomas D Bird Paul G Ince Pamela J Shaw Nigel J Cairns John C Morris Catriona Ann McLean Charles DeCarli William G Ellis Stefanie H Freeman Matthew P Frosch John H Growdon Daniel P Perl Mary Sano David A Bennett Julie A Schneider Thomas G Beach Eric M Reiman Bryan K Woodruff Jeffrey Cummings Harry V Vinters Carol A Miller Helena C Chui Irina Alafuzoff Päivi Hartikainen Danielle Seilhean Douglas Galasko Eliezer Masliah Carl W Cotman M Teresa Tuñón M Cristina Caballero Martínez David G Munoz Steven L Carroll Daniel Marson Peter F Riederer Nenad Bogdanovic Gerard D Schellenberg Hakon Hakonarson John Q Trojanowski Virginia M-Y Lee

Nat Genet 2010 Mar 14;42(3):234-9. Epub 2010 Feb 14.

[1] Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA. [2] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828525PMC
March 2010

Recent origin and spread of a common Welsh MAPT splice mutation causing frontotemporal lobar degeneration.

Neurogenetics 2009 Oct 14;10(4):313-8. Epub 2009 Apr 14.

Laboratory of Human Molecular Biology and Genetics, Catholic University of the Sacred Heart, Piazza Buonarroti 30, 20145, Milan, Italy.

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http://link.springer.com/10.1007/s10048-009-0189-x
Publisher Site
http://dx.doi.org/10.1007/s10048-009-0189-xDOI Listing
October 2009

TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease and frontotemporal lobar degeneration.

Acta Neuropathol 2008 Aug 28;116(2):141-6. Epub 2008 May 28.

Division of Biomedical and Life Sciences, School of Health and Medicine, University of Lancaster, Lancaster, UK.

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http://dx.doi.org/10.1007/s00401-008-0389-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2464623PMC
August 2008

Frequency and clinical characteristics of progranulin mutation carriers in the Manchester frontotemporal lobar degeneration cohort: comparison with patients with MAPT and no known mutations.

Brain 2008 Mar 11;131(Pt 3):721-31. Epub 2008 Jan 11.

Clinical Neuroscience Research Group, Faculty of Medical and Human Sciences, University of Manchester, Oxford Rd, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/brain/awm331DOI Listing
March 2008

The genetics of frontotemporal lobar degeneration.

Curr Opin Neurol 2007 Dec;20(6):693-8

Clinical Neurosciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1097/WCO.0b013e3282f1c961DOI Listing
December 2007

Progressive anomia revisited: focal degeneration associated with progranulin gene mutation.

Neurocase 2007 Oct;13(5):366-77

School of Translational Medicine, University of Manchester, Hope Hospital, Salford, UK.

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http://dx.doi.org/10.1080/13554790701851510DOI Listing
October 2007

The complex aetiology of frontotemporal lobar degeneration.

Exp Neurol 2007 Jul 24;206(1):1-10. Epub 2007 Mar 24.

Division of Regenerative Medicine, Stopford Building, University of Manchester, Oxford Road, Manchester, and Hope Hospital, Salford, M6 8HD, UK.

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http://dx.doi.org/10.1016/j.expneurol.2007.03.017DOI Listing
July 2007

Progranulin and frontotemporal lobar degeneration.

Acta Neuropathol 2007 Jul 16;114(1):39-47. Epub 2007 Jun 16.

Division of Regenerative Medicine, Stopford Building, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1007/s00401-007-0241-6DOI Listing
July 2007

TDP-43 gene analysis in frontotemporal lobar degeneration.

Neurosci Lett 2007 May 24;419(1):1-4. Epub 2007 Mar 24.

Division of Regenerative Medicine, Department of Medicine, University of Manchester, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1016/j.neulet.2007.03.044DOI Listing
May 2007

Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease.

Dement Geriatr Cogn Disord 2007 14;23(1):60-6. Epub 2006 Nov 14.

Clinical Neuroscience Research Group, Division of Medicine and Neuroscience, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Salford, UK.

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http://dx.doi.org/10.1159/000097038DOI Listing
February 2007

CHMP2B mutations are not a common cause of frontotemporal lobar degeneration.

Neurosci Lett 2006 May 23;398(1-2):83-4. Epub 2006 Jan 23.

Department of Neuroscience, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1016/j.neulet.2005.12.056DOI Listing
May 2006