Publications by authors named "Stuart Cook"

100Publications

Prolonged Beneficial Effect of Brief Erythropoietin Peptide JM4 Therapy on Chronic Relapsing EAE.

Neurotherapeutics 2020 Sep 21. Epub 2020 Sep 21.

Neurology Service, VA Medical Center of East Orange, East Orange, NJ, USA.

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http://dx.doi.org/10.1007/s13311-020-00923-5DOI Listing
September 2020

Targeting cardiac fibrosis in heart failure with preserved ejection fraction: mirage or miracle?

EMBO Mol Med 2020 Sep 21:e10865. Epub 2020 Sep 21.

MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.15252/emmm.201910865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539225PMC
September 2020

Gray Matter Nucleus Hyperintensity After Monthly Triple-Dose Gadopentetate Dimeglumine With Long-term Magnetic Resonance Imaging.

Invest Radiol 2020 Oct;55(10):629-635

From the *University of Connecticut, School of Medicine, Farmington, CT †Warren Alpert Medical School of Brown University, Providence, RI ‡University of Iowa, Carver College of Medicine Iowa City, IA §Washington University School of Medicine, St. Louis, MO ∥Rutgers University, New Jersey Medical School, Newark, NJ ¶University of Massachusetts Medical School, Worcester, MA.

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http://dx.doi.org/10.1097/RLI.0000000000000663DOI Listing
October 2020

Therapeutic Targeting of Interleukin-11 Signalling Reduces Pressure Overload-Induced Cardiac Fibrosis in Mice.

J Cardiovasc Transl Res 2020 Jun 26. Epub 2020 Jun 26.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1007/s12265-020-10054-zDOI Listing
June 2020

Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy.

Hum Vaccin Immunother 2020 Jun 12:1-6. Epub 2020 Jun 12.

Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School , Singapore.

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http://dx.doi.org/10.1080/21645515.2020.1761203DOI Listing
June 2020

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors.

Cell Rep 2020 May;31(8):107714

Cardiovascular & Metabolic Disorders Program, Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore; Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.107714DOI Listing
May 2020

The remodelling index risk stratifies patients with hypertensive left ventricular hypertrophy.

Eur Heart J Cardiovasc Imaging 2020 Apr 7. Epub 2020 Apr 7.

Department of Cardiology, National Heart Center Singapore, Singapore.

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http://dx.doi.org/10.1093/ehjci/jeaa040DOI Listing
April 2020

Evaluation of family health history collection methods impact on data and risk assessment outcomes.

Prev Med Rep 2020 Jun 5;18:101072. Epub 2020 Mar 5.

SingHealth Duke-NUS Institute of Precision Medicine, Duke-National University of Singapore Medical School, Singapore.

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http://dx.doi.org/10.1016/j.pmedr.2020.101072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066218PMC
June 2020

Emerging Techniques for Risk Stratification in Nonischemic Dilated Cardiomyopathy: JACC Review Topic of the Week.

J Am Coll Cardiol 2020 Mar;75(10):1196-1207

Department of Cardiovascular Sciences, University of Leicester and the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.12.058DOI Listing
March 2020

Do innate killing mechanisms activated by inflammasomes have a role in treating melanoma?

Pigment Cell Melanoma Res 2020 09 20;33(5):660-670. Epub 2020 Feb 20.

Melanoma Immunology and Oncology Group, The Centenary Institute, Royal Prince Alfred Hospital, University of Sydney, Camperdown, New South Wales, Australia.

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http://dx.doi.org/10.1111/pcmr.12870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497247PMC
September 2020

IL-11 in cardiac and renal fibrosis: Late to the party but a central player.

Br J Pharmacol 2020 Apr 22;177(8):1695-1708. Epub 2020 Feb 22.

National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore.

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http://dx.doi.org/10.1111/bph.15013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070163PMC
April 2020

Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation.

Annu Rev Med 2020 01;71:263-276

Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 169857 Singapore, Singapore; email:

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http://dx.doi.org/10.1146/annurev-med-041818-011649DOI Listing
January 2020

Cardiac structure and function in schizophrenia: cardiac magnetic resonance imaging study.

Br J Psychiatry 2020 Aug;217(2):450-457

Professor of Molecular Psychiatry, MRC London Institute of Medical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus; and Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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http://dx.doi.org/10.1192/bjp.2019.268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511899PMC
August 2020

deltaTE: Detection of Translationally Regulated Genes by Integrative Analysis of Ribo-seq and RNA-seq Data.

Curr Protoc Mol Biol 2019 12;129(1):e108

Program in Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore.

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http://dx.doi.org/10.1002/cpmb.108DOI Listing
December 2019

Letter to the editor.

Mult Scler Relat Disord 2019 09 19;34:164. Epub 2019 Jun 19.

217 West Beaver Ave, State College, PA 16801 United States.

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http://dx.doi.org/10.1016/j.msard.2019.06.020DOI Listing
September 2019

The Translational Landscape of the Human Heart.

Cell 2019 06 30;178(1):242-260.e29. Epub 2019 May 30.

Cardiovascular and Metabolic Sciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, 13347 Berlin, Germany; Berlin Institute of Health (BIH), 10178 Berlin, Germany; Charité-Universitätsmedizin, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.05.010DOI Listing
June 2019

Feasibility to Perform T * Mapping Postcontrast Administration in Reperfused STEMI Patients for the Detection of Intramyocardial Hemorrhage.

J Magn Reson Imaging 2020 02 14;51(2):644-645. Epub 2019 May 14.

Department of Cardiology, National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.

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http://dx.doi.org/10.1002/jmri.26779DOI Listing
February 2020

Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.

Gastroenterology 2019 09 9;157(3):777-792.e14. Epub 2019 May 9.

Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore; National Heart and Lung Institute, Imperial College London, London, UK; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.05.002DOI Listing
September 2019

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors.

Cell Rep 2019 03;26(12):3231-3245.e9

Cardiovascular & Metabolic Disorders Program, Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore; Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 77 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.083DOI Listing
March 2019

Safety of cladribine tablets in the treatment of patients with multiple sclerosis: An integrated analysis.

Mult Scler Relat Disord 2019 Apr 20;29:157-167. Epub 2018 Nov 20.

Merck KGaA, Frankfurter Str. 250, 64293 Darmstadt, Germany.

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http://dx.doi.org/10.1016/j.msard.2018.11.021DOI Listing
April 2019

Sudden Death and Left Ventricular Involvement in Arrhythmogenic Cardiomyopathy.

Circulation 2019 04;139(15):1786-1797

Cardiology Clinical Academic Group, St George's University Hospitals' NHS Foundation Trust and Molecular and Clinical Sciences Institute, St George's University of London, United Kingdom (C.M., G.F., M.P., B.G., J.W., B.E., J.B., G.P.-W., E.P. C.P., A.M., A.A., M.T., S.S., E.R.B., M.N.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.037230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467560PMC
April 2019

Using High-Resolution Variant Frequencies Empowers Clinical Genome Interpretation and Enables Investigation of Genetic Architecture.

Am J Hum Genet 2019 01;104(1):187-190

Cardiovascular Genetics and Genomics, National Heart and Lung Institute, Imperial College Centre for Translational and Experimental Medicine, London, W12 0NN, UK; National Institute for Health Research Royal Brompton Cardiovascular Research Centre, Royal Brompton and Harefield National Health Service Foundation Trust, London, SW7 2AZ, UK; Medical Research Council London Institute of Medical Sciences, Imperial College London, London, W12 0NN, UK; Program in Medical and Population Genetics, Broad Institute of the Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323549PMC
January 2019

Early Regenerative Capacity in the Porcine Heart.

Circulation 2018 12;138(24):2798-2808

National Heart Research Institute Singapore, National Heart Centre Singapore (L.Y., S.J.L., C.X.W., L.P.S., S.H.T., G.Z.T., C.J.P., R.S.T., S.A.C.).

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http://circ.ahajournals.org/lookup/doi/10.1161/CIRCULATIONAH
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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031542DOI Listing
December 2018

Differential chemokine receptor expression and usage by pre-cDC1 and pre-cDC2.

Immunol Cell Biol 2018 11 20;96(10):1131-1139. Epub 2018 Jul 20.

Centenary Institute, Newtown, NSW, Australia.

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http://dx.doi.org/10.1111/imcb.12186DOI Listing
November 2018

Fractal Analysis of Right Ventricular Trabeculae in Pulmonary Hypertension.

Radiology 2018 08 5;288(2):386-395. Epub 2018 Jun 5.

From the MRC London Institute of Medical Sciences, Faculty of Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Rd, London W12 0HS, England (T.J.W.D., M.Q., A.d.M., P.J.O., P.F.T., S.A.C., D.P.O.); National Heart and Lung Institute (T.J.W.D., J.S.R.G., S.A.C.), and Division of Experimental Medicine, Department of Medicine (G.M.J.W., J.W., M.R.W.), Imperial College London, London, England; National Heart Centre Singapore, Singapore, and Duke-NUS Graduate Medical School, Singapore (J.C., S.A.C.); and Department of Cardiology, National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, London, England (L.S.G.E.H., J.S.R.G.).

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http://dx.doi.org/10.1148/radiol.2018172821DOI Listing
August 2018

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials.

Mult Scler 2019 04 9;25(4):565-573. Epub 2018 Mar 9.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, München, Germany/German Competence Network Multiple Sclerosis (KKNMS), München, Germany/Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1177/1352458518763089DOI Listing
April 2019

Role of titin in cardiomyopathy: from DNA variants to patient stratification.

Nat Rev Cardiol 2018 04 14;15(4):241-252. Epub 2017 Dec 14.

National Heart and Lung Institute, Imperial College London, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

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http://dx.doi.org/10.1038/nrcardio.2017.190DOI Listing
April 2018

Phenotype and Clinical Outcomes of Titin Cardiomyopathy.

J Am Coll Cardiol 2017 Oct;70(18):2264-2274

National Heart Lung Institute, Imperial College London, London, United Kingdom; Cardiovascular Research Centre, Royal Brompton Hospital, London, United Kingdom; Medical Research Council London Institute of Medical Sciences, Imperial College London, London, United Kingdom; National Heart Centre, Singapore; Duke-NUS Medical School, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2017.08.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5666113PMC
October 2017

Three-dimensional cardiovascular imaging-genetics: a mass univariate framework.

Bioinformatics 2018 01;34(1):97-103

Cardiovascular Magnetic Resonance Imaging and Genetics, MRC London Institute of Medical Sciences, Imperial College London, Hammersmith Hospital Campus, London, UK.

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http://dx.doi.org/10.1093/bioinformatics/btx552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870605PMC
January 2018

Novel Index of Maladaptive Myocardial Remodeling in Hypertension.

Circ Cardiovasc Imaging 2017 Sep;10(9)

From the Department of Internal Medicine, Singapore General Hospital, Singapore (V.J.G.); Department of Cardiology, National Heart Centre Singapore (T.-T.L., J.B., J.I.W., B.S., C.J.P., C.P.Y.S., B.A., S.A.C., C.W.L.C.); National University Heart Centre Singapore (C.-H.L.); Duke-NUS Medical School, Singapore, Singapore (S.A.C., C.W.L.C.); and Depatrment of Laboratory Medicine, Changi General Hospital, Singapore (T.C.A.).

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http://dx.doi.org/10.1161/CIRCIMAGING.117.006840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617557PMC
September 2017

MRI evidence of acute inflammation in leukocortical lesions of patients with early multiple sclerosis.

Neurology 2017 Aug 19;89(7):714-721. Epub 2017 Jul 19.

From the Department of Neurology and Neurosurgery (J.M., D.A.R., K.N., D.L.A., S.N.), Montreal Neurological Hospital and Institute, McGill University, Canada; Cleveland Clinic (K.N.), OH; Rutgers-New Jersey Medical School (S.C., D.C.), Newark, NJ; and Case Western Reserve University (L.W.), Cleveland, OH. L.W. is currently with the University of Connecticut, School of Medicine, Farmington.

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http://dx.doi.org/10.1212/WNL.0000000000004227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562966PMC
August 2017

Stability of visual outcome between 2 and 5 years following corneal transplantation in the UK.

Br J Ophthalmol 2018 01 9;102(1):37-41. Epub 2017 Jun 9.

Tissue and Eye Services, National Health Service Blood and Transplant (NHSBT), Bristol, UK.

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http://dx.doi.org/10.1136/bjophthalmol-2016-310129DOI Listing
January 2018

Using high-resolution variant frequencies to empower clinical genome interpretation.

Genet Med 2017 10 18;19(10):1151-1158. Epub 2017 May 18.

Cardiovascular Genetics and Genomics, National Heart and Lung Institute, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/gim.2017.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563454PMC
October 2017

Association Between Midwall Late Gadolinium Enhancement and Sudden Cardiac Death in Patients With Dilated Cardiomyopathy and Mild and Moderate Left Ventricular Systolic Dysfunction.

Circulation 2017 May 28;135(22):2106-2115. Epub 2017 Mar 28.

From National Institute for Health Research Cardiovascular Biomedical Research Unit and Cardiovascular Magnetic Resonance Unit (B.P.H., A.G., A.A., M.A., V.S.V., A.L. C.I., U.T. Z.K., D.A., F.A., J.G.F.C., S.A.C., D.J.P., S.K.P.), Department of Cardiology (K.G., N.P., S.D.R., A.V., M.R.C.), Royal Brompton Hospital, London, United Kingdom; National Heart and Lung Institute, Imperial College, London, United Kingdom (B.P.H., A.A., K.G., V.S.V., A.L., U.T., S.D.R., A.V., F.A., M.R.C., J.G.F.C., S.A.C., D.J.P., S.K.P.); London School of Hygiene and Tropical Medicine, United Kingdom (S.N., J.G.); Norwich Medical School, University of East Anglia, United Kingdom (V.S.V., M.P.F); Centre for Cardiovascular Science, University of Edinburgh, United Kingdom (C.S.); King's College London and Department of Cardiology, Guy's and St Thomas' Hospital, London, United Kingdom (T.F.I.); Department of Cardiology, Ealing Hospital, London, United Kingdom (S.D.R.); and National Heart Centre Singapore (S.A.C.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.116.0
Publisher Site
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444425PMC
May 2017