Stuart Connolly

Stuart Connolly

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Stuart Connolly

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Thromboembolic events around the time of cardioversion for atrial fibrillation in patients receiving antiplatelet treatment in the ACTIVE trials.

Eur Heart J 2019 Aug 4. Epub 2019 Aug 4.

Population Health Research Institute, McMaster University, 30 Birge St. Room C3-121, Hamilton, Ontario L8L 0A6, Canada.

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http://dx.doi.org/10.1093/eurheartj/ehz521DOI Listing
August 2019

Rivaroxaban Plus Aspirin Versus Aspirin in Relation to Vascular Risk in the COMPASS Trial.

J Am Coll Cardiol 2019 Jul;73(25):3271-3280

Department of Medicine, Population Health Research Institute, McMaster University, Hamilton Health Sciences, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2019.02.079DOI Listing
July 2019

Andexanet Alfa for Bleeding with Factor Xa Inhibitors. Reply.

N Engl J Med 2019 07;381(2):192-193

Portola Pharmaceuticals, South San Francisco, CA.

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http://dx.doi.org/10.1056/NEJMc1906058DOI Listing
July 2019

Individual Treatment Effect Estimation of 2 Doses of Dabigatran on Stroke and Major Bleeding in Atrial Fibrillation.

Circulation 2019 Jun 3;139(25):2846-2856. Epub 2019 May 3.

Department of Vascular Medicine, University Medical Center Utrecht, The Netherlands (M.C.S.-S., J.v.d.L., J.A.N.D., F.L.J.V.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035266DOI Listing
June 2019

Rivaroxaban Plus Aspirin in Patients With Vascular Disease and Renal Dysfunction: From the COMPASS Trial.

J Am Coll Cardiol 2019 May;73(18):2243-2250

Department of Medicine, McMaster University, Hamilton, Ontario, Canada; Population Health Research Institute, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2019.02.048DOI Listing
May 2019

Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors.

N Engl J Med 2019 04 7;380(14):1326-1335. Epub 2019 Feb 7.

From the Population Health Research Institute (S.J.C., J.W.E., D.M.S., E.Z., B.M., S.A., J.N.) and the Department of Medicine (M. Crowther), McMaster University, Hamilton, ON, and the University of Calgary, Calgary, AB (A.M.D.) - all in Canada; Harvard Medical School (C.M.G.) and Brigham and Women's Hospital (D.J.P.) - both in Boston; Portola Pharmaceuticals, South San Francisco, CA (J.T.C., J.H.L., P.Y., M.D.B., G.L., P.B.C., S.G., J.L., S.S.); University of Leuven, Leuven, Belgium (P.V.); Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand (J.S.), and Grenoble-Alpes University Hospital, Grenoble (P.A.) - both in France; Academic Medical Center, Amsterdam (S.M.); Guy's and St. Thomas' Hospitals, King's College London, London (A.T.C.); University Hospital Carl Gustav Carus Dresden, Dresden, Germany (J.B.-W.); Instituto de Investigación Hospital Universitario La Paz, Madrid (J.L.-S.); Sarasota Memorial Hospital, Sarasota, FL (M. Concha); and Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.).

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http://dx.doi.org/10.1056/NEJMoa1814051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699827PMC
April 2019

Perspective and practice of surgical atrial fibrillation ablation: an international survey of cardiac surgeons.

Europace 2019 Mar;21(3):445-450

Department of Health Research Methods, Evidence and Impact, McMaster University, 237 Barton Street East, Hamilton, ON, Canada.

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https://academic.oup.com/europace/advance-article/doi/10.109
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http://dx.doi.org/10.1093/europace/euy212DOI Listing
March 2019

When and how should we cluster and cross over: methodological and ethical issues (letter 1).

Can J Anaesth 2019 Feb 17;66(2):234-236. Epub 2018 Oct 17.

Department of Medicine (Cardiology), Population Health Research Institute (PHRI), McMaster University, Hamilton, ON, Canada.

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http://link.springer.com/10.1007/s12630-018-1237-5
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http://dx.doi.org/10.1007/s12630-018-1237-5DOI Listing
February 2019

When and how should we cluster and cross over: methodological and ethical issues (letter 2).

Can J Anaesth 2019 Feb 19;66(2):237-238. Epub 2018 Oct 19.

McMaster University, Population Health Research Institute (PHRI), Hamilton, ON, Canada.

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http://link.springer.com/10.1007/s12630-018-1238-4
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http://dx.doi.org/10.1007/s12630-018-1238-4DOI Listing
February 2019

Stroke Outcomes in the COMPASS Trial.

Circulation 2019 Feb;139(9):1134-1145

McMaster University/Population Health Research Institute, Hamilton, Canada (M.S., R.G.H., S.J.C., J.B., O.S., K.K.H.N., L.C., S.Y., J.W.E.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035864DOI Listing
February 2019

Idarucizumab for Dabigatran-Related Gastrointestinal Bleeds.

Circulation 2019 Feb;139(6):757-759

Department of Medicine, McMaster University, Hamilton, Ontario, Canada (D.M.S., S.J.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038460DOI Listing
February 2019

Rivaroxaban, Aspirin, or Both to Prevent Early Coronary Bypass Graft Occlusion: The COMPASS-CABG Study.

J Am Coll Cardiol 2019 Jan;73(2):121-130

Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183906
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http://dx.doi.org/10.1016/j.jacc.2018.10.048DOI Listing
January 2019

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.

N Engl J Med 2018 09;379(10):987

Bayer, Wuppertal, Germany

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http://dx.doi.org/10.1056/NEJMc1809065DOI Listing
September 2018

Locations and Mucosal Lesions Responsible for Major Gastrointestinal Bleeding in Patients on Warfarin or Dabigatran.

Dig Dis Sci 2018 07 27;63(7):1878-1889. Epub 2018 Mar 27.

Department of Gastroenterology and Hepatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1007/s10620-018-5007-6DOI Listing
July 2018

Concomitant Oral Anticoagulant and Nonsteroidal Anti-Inflammatory Drug Therapy in Patients With Atrial Fibrillation.

J Am Coll Cardiol 2018 07 9;72(3):255-267. Epub 2018 Jul 9.

Sidney Kimmel Medical College at Thomas Jefferson University and Lankenau and Bryn Mawr Hospitals, Philadelphia, Pennsylvania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183482
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http://dx.doi.org/10.1016/j.jacc.2018.04.063DOI Listing
July 2018

Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source.

N Engl J Med 2018 Jun 16;378(23):2191-2201. Epub 2018 May 16.

From the Departments of Medicine-Neurology (R.G.H., M.S., A.S.), Health Research Methods, Evidence, and Impact (S.I.B.), Pathology and Molecular Medicine (G. Pare), and Medicine-Cardiology (S.J.C.), Population Health Research Institute (B.S., P.S., E.T.), and the Thrombosis and Atherosclerosis Research Institute and McMaster University (J.I.W.), Hamilton, ON, the Vancouver Stroke Program, University of British Columbia, Vancouver (O.R.B.), and Sunnybrook Health Sciences Centre, University of Toronto, Toronto (C.J.) - all in Canada; Bayer, Wuppertal (H.M.), Klinik für Neurologie, Charité-Universitätsmedizin Berlin (M.E.), and Bayer (B.K.), Berlin, and Bayer, Leverkusen (C.P.) - all in Germany; the Department of Neurology, University of Pennsylvania, Philadelphia (S.E.K.), and Janssen Research and Development, Spring House (G. Peters) - both in Pennsylvania; Bayer U.S., Pharmaceuticals Clinical Development Thrombosis, Whippany, NJ (S.D.B.); Clínica Alemana de Santiago, Santiago, Chile (P.L.); the Department of Neurology and Stroke Center, Beijing Tiantan Hospital, Beijing (Yongjun Wang, Yilong Wang); Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona (A.D.); Pirogov Russian National Research Medical University, Moscow (N.S.); International Clinical Research Center and Neurology Department, St. Anne's University Hospital, Brno, Czech Republic (R.M.); Centro Hospitalar e Universitário de Coimbra, Hospitais da Universidade de Coimbra, Coimbra, Portugal (L.C.); the Department of Clinical Sciences (Neurology), Lund University, and the Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund (A.L.), and the Department of Clinical Neuroscience-Neurology, Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Gothenburg (T.T.) - all in Sweden; Instituto Nacional de Neurología y Neurocirugía, Mexico City (A.A.); Hospital St. John of God, Sigmund Freud Private University, Medical Faculty, Vienna (W.L.); the 2nd Department of Neurology, Institute of Psychiatry and Neurology, and the Department of Pharmacology, Medical University of Warsaw, Warsaw, Poland (A.C.); the Department of Internal Medicine, University Hospital Basel, Basel, Switzerland (J.E.); Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo (R.J.G.); Assistance Publique-Hôpitaux de Paris, Bichat Hospital, Paris-Diderot, Sorbonne Paris Cité University, Paris (P.A.); Institute for Neurological Research-Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia, Buenos Aires (S.F.A.); the Department of Neurology, Helsinki University Central Hospital, Helsinki (T.T.); Imperial College London, London (R.V.); Medical School, University of Western Australia, and Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); the Department of Human Neurosciences, Sapienza University of Rome, Rome (D.T.); the Department of Neurology, Semmelweis University, Budapest, Hungary (D.B.); International University of Health and Welfare, Sanno Hospital and Sanno Medical Center, Tokyo (S.U.); the Department of Medicine, University of Thessaly, Larissa, Greece (G.N.); Seoul National University College of Medicine, Seoul National University Hospital, Seoul, South Korea (B.-W.Y.); the Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Brussels (R.B.); the Department of Neurology, ZorgSaam Hospital, Terneuzen, the Netherlands (R.B.); Institute of Neuroscience and Psychology, University of Glasgow, Queen Elizabeth University Hospital, Glasgow, United Kingdom (K.W.M.); Shaare Zedek Medical Center, Jerusalem (N.B.); the Department of Neurology, Selcuk University, Konya, Turkey (S.O.); Health Research Board Clinical Research Facility, National University of Ireland, Galway (M.J.O.); Tiervlei Trial Centre and Head of Internal Medicine Karl Bremer Hospital, Bellville, South Africa (M.M.D.V.B.); and Baylor College of Medicine, Houston (W.F.P.).

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http://dx.doi.org/10.1056/NEJMoa1802686DOI Listing
June 2018

Efficacy and safety of dabigatran compared with warfarin in patients with atrial fibrillation in relation to renal function over time-A RE-LY trial analysis.

Am Heart J 2018 04 5;198:169-177. Epub 2018 Jan 5.

Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden; Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ahj.2017.10.015DOI Listing
April 2018

Implantable cardioverter-defibrillator therapy in hypertrophic cardiomyopathy: A SIMPLE substudy.

Heart Rhythm 2018 03 20;15(3):386-392. Epub 2017 Nov 20.

University Hospital Frankfurt, Goethe University, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.11.020DOI Listing
March 2018

Predictors of Mortality in Patients With Atrial Fibrillation (from the Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events [ACTIVE A]).

Am J Cardiol 2018 03 11;121(5):584-589. Epub 2017 Dec 11.

Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.11.028DOI Listing
March 2018

Effectiveness of implementation interventions in improving physician adherence to guideline recommendations in heart failure: a systematic review.

BMJ Open 2018 03 6;8(3):e017765. Epub 2018 Mar 6.

Department of Medicine and Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjopen-2017-017765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855256PMC
March 2018

Atrial fibrillation occurring transiently with stress.

Curr Opin Cardiol 2018 Jan;33(1):58-65

Population Health Research Institute and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/HCO.0000000000000475DOI Listing
January 2018

Impact of Clopidogrel Therapy on Mortality and Cancer in Patients With Cardiovascular and Cerebrovascular Disease: A Patient-Level Meta-Analysis.

Circ Cardiovasc Interv 2018 01;11(1):e005795

From the Cardiology Division, Department of Medicine, Massachusetts General Hospital (S.E.), Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital (D.L.B., L.M.), Smith Center for Outcomes Research in Cardiology, Department of Medicine, Beth-Israel Deaconess Medical Center (R.W.Y.), Harvard Medical School, Boston, MA (S.E., D.L.B., R.W.Y., L.M.); Baim Institute for Clinical Research, Boston, MA (S.E., G.D., Y.L., W.-H.H., R.W.Y., L.M.); Department of Biostatistics, Boston University School of Public Health, MA (G.D.); University of British Columbia, Vancouver, Canada (O.R.B.); Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada (S.J.C., S.Y.); and Scripps Translational Science Institute, La Jolla, CA (S.R.S.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.117.005795DOI Listing
January 2018

Rivaroxaban in Stable Cardiovascular Disease.

N Engl J Med 2018 01;378(4):397-398

Population Health Research Institute, Hamilton, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1714934DOI Listing
January 2018

Thoracoscopic Left Atrial Appendage Occlusion: We Can Do It, Now Should We?

JACC Clin Electrophysiol 2017 12 30;3(12):1366-1368. Epub 2017 Aug 30.

Department of Medicine, Population Health Research Institute, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacep.2017.05.015DOI Listing
December 2017

Comparative effectiveness of transitional care services in patients discharged from the hospital with heart failure: a systematic review and network meta-analysis.

Eur J Heart Fail 2017 11 24;19(11):1427-1443. Epub 2017 Feb 24.

Department of Medicine, McMaster University, and Population Health Research Institute, Hamilton, ON, Canada.

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http://dx.doi.org/10.1002/ejhf.765DOI Listing
November 2017

Another Dimension of Safety in the Prescription of Anticoagulants for Nonvalvular Atrial Fibrillation.

J Am Coll Cardiol 2017 11;70(21):2633-2635

Population Health Research Institute, Hamilton Health Sciences/McMaster University, Hamilton, Ontario, Canada; Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jacc.2017.09.1103DOI Listing
November 2017

Subclinical Atrial Fibrillation in Older Patients.

Circulation 2017 Oct 4;136(14):1276-1283. Epub 2017 Aug 4.

From Population Health Research Institute, Hamilton, ON, Canada (J.S.H., J.W., D.L., H.D., K.S., S.R.M., S.J.C.); McMaster University, Hamilton, ON, Canada (J.S.H., J.W., D.L., H.D., W.F.M., S.R.M., A.S.P., S.J.C.); Amphia Ziekenhuis, Breda, the Netherlands (M.A.); WCN-Dutch Network for Cardiovascular Research (M.A.); University of Toronto, ON, Canada (A.H., A.V.); University of Western Ontario, London, Canada (P.L.-S.); University of Ottawa Heart Institute, ON, Canada (D.H.B.); Nij Smellinghe Hospital, Drachten, the Netherlands (J.J.d.G.); Ikazia Ziekenhuis, Rotterdam, the Netherlands (M.F.); Institut Universitaire de Cardiologie et de Pneumologie de Québec, QC, Canada (F.P.); University of Alberta, Edmonton, Canada (W.B.); University of Calgary, AB, Canada (M.D.H.); St. Jude Medical, Sylmar, CA (M.C.); Slingeland Ziekenhuis, Doetinchem, the Netherlands (F.S.); and Cambridge Cardiac Care Centre, ON, Canada (A.S.P.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028845DOI Listing
October 2017

Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease.

N Engl J Med 2017 10 27;377(14):1319-1330. Epub 2017 Aug 27.

From the Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON (J.W.E., S.J.C., J.B., R.G.H., O.S., E.M.L., S.S.A., D.L., S.Y.), and Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec, QC (G.R.D.) - both in Canada; Estudios Clínicos Latino América and Instituto Cardiovascular de Rosario, Rosario, Argentina (R.D.); Amphia Ziekenhuis and Werkgroep Cardiologische Centra Nederland (WCN), Utrecht, the Netherlands (M.A.); Cardiocenter, University Hospital Kralovske Vinohrady and Third Faculty of Medicine, Charles University, Prague, Czech Republic (P.W.); Osaka International Cancer Institute, Osaka, Japan (M.H.); Instituto Dante Pazzanese de Cardiologia (A.A.), and Hospital do Coração (L.S.P.), São Paulo; University of Washington Medical Center (K.R.H.B.) and University of Washington (J.P.), Seattle; Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston (D.L.B.); FuWai Hospital, Beijing (J.Z., Y.L.); National Association of Hospital Cardiologists Research Center (ANMCO), Florence, Italy (A.P.M.); Research Institute, Fundación Oftalmológica de Santander (FOSCAL)-Bucaramanga, Bucaramanga, Colombia (P.L.-J.); National University of Ireland, Galway (M.O.); Thrombosis Research Institute and University College London, London (A.K.K.), Centre for Cardiovascular Science, University of Edinburgh, Edinburgh (K.A.A.F.), and University of Glasgow, Glasgow (T.J.G.) - all in the United Kingdom; Collegium Medicum Jagiellonian University, Krakow, Poland (T.J.G); Institute of Cardiology, Kiev, Ukraine (A.N.P.); University of Würzburg and University Hospital, Würzburg (G.E., S.S.), and Bayer, Leverkusen (N.C.B., F.M., E.C.) - all in Germany; Semmelweis University, Budapest, Hungary (M.K.); Karolinska Institutet, Stockholm (L.R.); National Research Center for Preventative Medicine, Moscow (N.P.); University of Philippines, Manila (A.L.D.); Universidad de La Frontera, Temuco, Chile (F.L.); University of Cape Town, Cape Town, South Africa (P.J.C.); University of Aalborg, Copenhagen (C.T.-P.); University of Leuven, Leuven, Belgium (P.B.V.); University of Medicine and Pharmacology, Carol Davila University and Emergency Hospital, Bucharest, Romania (D.V.); Catholic University of Korea, Seoul, South Korea (J.-H.K.); Monash University, Melbourne, VIC, Australia (A.M.T.); Lady Davis Carmel Medical Center, Haifa, Israel (B.S.L.); Facultad de Ciencias de la Salud Eugenio Espejo-Universidad Tecnológica Equinoccial, Quito, Ecuador (C.F.); Universiti Teknologi Mara, Selangor, Malaysia (K.Y.); Université Paris Diderot, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris (P.G.S.); and Turku University Central Hospital and Turku University, Turku, Finland (K.P.M.).

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http://dx.doi.org/10.1056/NEJMoa1709118DOI Listing
October 2017

Growth-differentiation factor 15 and risk of major bleeding in atrial fibrillation: Insights from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) trial.

Am Heart J 2017 Aug 6;190:94-103. Epub 2017 Jun 6.

Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden; Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.ahj.2017.06.001DOI Listing
August 2017

Effects of dabigatran according to age in atrial fibrillation.

Heart 2017 07 17;103(13):1015-1023. Epub 2017 Feb 17.

McMaster University and Hamilton Health Sciences, Population Health Research Institute, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1136/heartjnl-2016-310358DOI Listing
July 2017

Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT.

Eur Heart J 2017 May;38(17):1339-1344

Population Health Research Institute, McMaster University, 237 Barton Street East, Hamilton, ON L8L 2X2, Canada.

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http://dx.doi.org/10.1093/eurheartj/ehx042DOI Listing
May 2017

Laboratory Monitoring of Non-Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation: A Review.

JAMA Cardiol 2017 05;2(5):566-574

Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada3Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada4Hamilton Health Sciences, Hamilton, Ontario, Canada6Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1001/jamacardio.2017.0364DOI Listing
May 2017

Embolic Stroke of Undetermined Source: A Systematic Review and Clinical Update.

Stroke 2017 04 6;48(4):867-872. Epub 2017 Mar 6.

From the Department of Medicine (Neurology) (R.G.H., L.C., K.S.P.), Population Health Research Institute and Department of Medicine (Cardiology) (S.J.C.), McMaster University, Hamilton Health Sciences, Ontario, Canada; Department of Medicine, Larissa University Hospital, University of Thessaly, Larissa, Greece (G.N.).

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http://dx.doi.org/10.1161/STROKEAHA.116.016414DOI Listing
April 2017

Reduction in unnecessary ventricular pacing fails to affect hard clinical outcomes in patients with preserved left ventricular function: a meta-analysis.

Europace 2017 02;19(2):282-288

Arrhythmia Services, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Room E241, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada.

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http://dx.doi.org/10.1093/europace/euw221DOI Listing
February 2017

Anticoagulant-Related Bleeding and Mortality.

J Am Coll Cardiol 2016 12;68(23):2522-2524

Population Health Research Institute, McMaster University, Hamilton Health Sciences, Hamilton, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.10.005DOI Listing
December 2016

Andexanet Alfa for Factor Xa Inhibitor Reversal.

N Engl J Med 2016 12;375(25):2499-500

McMaster University, Hamilton, ON, Canada

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http://dx.doi.org/10.1056/NEJMc1613270DOI Listing
December 2016

Performance and Validation of a Novel Biomarker-Based Stroke Risk Score for Atrial Fibrillation.

Circulation 2016 Nov 28;134(22):1697-1707. Epub 2016 Aug 28.

From Department of Medical Sciences, Cardiology, Uppsala University, Sweden (J.O., Z.H., L.W.); Uppsala Clinical Research Center, Uppsala University, Sweden (J.O., Z.H., J.L., A.S., L.W.); Duke Clinical Research Institute, Duke Medicine, Durham, NC (J.H.A., C.B.G., R.D.L.); Population Health Research Institute, Hamilton, Canada (S.J.C., J.W.E., S.Y.); Thomas Jefferson Medical College and the Heart Center, Wynnewood, PA (M.D.E.); Boston University Medical Center, MA (E.M.H.); and Department of Medical Sciences, Clinical Chemistry, Uppsala University, Sweden (A.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022802DOI Listing
November 2016

Global Survey of the Frequency of Atrial Fibrillation-Associated Stroke: Embolic Stroke of Undetermined Source Global Registry.

Stroke 2016 09 9;47(9):2197-202. Epub 2016 Aug 9.

From the Population Health Research Institute, McMaster University, Hamilton Health Sciences, Ontario, Canada (K.S.P., J.B., B.S., M.G., S.J.C., R.G.H.); Department of Cardiovascular Sciences, University of Leuven, Belgium (T.V.); Bayer-Pharma AG, Wuppertal, Germany (H.M.); Instituto Nacional de Neurologia y Neurocirugia, Mexico D.F., Mexico (M.A.B.); University of Galway, Ireland (M.J.O.); Institute for Neurological Research, Fundacion para la Lucha contra las Enfermedades Neurologicas de la Infancia (FLENI), Buenos Aires, Argentina (M.G.-S.); School of Medicine and Pharmacology, University of Western Australia, Sir Charles Gairdner Hospital, Perth, Australia (G.J.H.); Department of Neurology, Seoul National University Hospital, Korea (B.-W.Y.); Medical City Hospital, Manila, Philippines (A.R.); Department of Neurology, Bichat Hospital, Paris, France (P.L.); Centro Hospitalar e Universitário de Coimbra, Portugal (J.S.-F.); Pirogov Russian National Research Medical University, Moscow, Russia (N.S.); Universitair Ziekenhuis Brussel, Belgium (R.B.); Santa Casa de São Paulo, Medical School, Brazil (R.J.G.); Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia (S.E.K.); Emergency Department Stroke Unit, Hospital Policlinico Umberto I, Department of Neurology and Psychiatry, 'Sapienza' University, Rome, Italy (A.P.); Department of Neurology, University Hospital Heidelberg, Germany (P.V.); Department of Neurology, Tokyo Women's Medical University, Japan (K.K.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Institute of Neuroscience & Psychology, University of Glasgow, Queen Elizabeth University Hospital, United Kingdom (K.M.); and Academic Medical Center, Amsterdam, the Netherlands (J.M.C.).

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http://dx.doi.org/10.1161/STROKEAHA.116.013378DOI Listing
September 2016

Andexanet Alfa for Acute Major Bleeding Associated with Factor Xa Inhibitors.

N Engl J Med 2016 09 30;375(12):1131-41. Epub 2016 Aug 30.

From the Population Health Research Institute, McMaster University, Hamilton ON, Canada (S.J.C., J.W.E., D.M.S., E.Z., B.M., J.N., W.T.L., M.C.); Seton Dell Medical School Stroke Institute, Austin, TX (T.J.M.); Harvard Medical School, Boston (C.M.G.); Portola Pharmaceuticals, San Francisco (J.T.C., A.G., M.D.B., G.L., P.B.C., S.G., J.L., B.L.W.); University of Leuven, Leuven, Belgium (P.V.); Centre Hospitalier Universitaire de Clermont-Ferrand, Clermont-Ferrand (J.S.), and Grenoble-Alpes University Hospital, Grenoble (P.A.) - both in France; Academic Medical Center, Amsterdam (S.M.); Guy's and St. Thomas' Hospitals, King's College London, London (A.T.C.); University Hospital Carl Gustav Carus Dresden, Dresden, Germany (J.B.-W.); and Hospital Universitario La Paz, Madrid (J.L.-S.).

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http://dx.doi.org/10.1056/NEJMoa1607887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568772PMC
September 2016

Comparison of Dabigatran and Warfarin in Patients With Atrial Fibrillation and Valvular Heart Disease: The RE-LY Trial (Randomized Evaluation of Long-Term Anticoagulant Therapy).

Circulation 2016 Aug 5;134(8):589-98. Epub 2016 Aug 5.

From Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA (M.D.E.); Cardiovascular Research Foundation, New York, NY (M.D.E., C.L.); Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ (R.N.); Electrophysiology Research Foundation, Warren, NJ (R.N.); Boehringer Ingelheim GmbH & Co, Ingelheim am Rhein, Germany (H.N., M.B.); Faculty of Medicine Mannheim, University of Heidelberg, Mannheim, Germany (M.B.); Albert Einstein College of Medicine, New York, NY (M.J.); Center for Thrombosis and Hemostasis, University Medical Center Mainz, Germany (A.C.); Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT (P.A.R.); McMaster University, Hamilton, Canada (S.J.C., S.Y.); and Uppsala Clinical Research Center, Uppsala, Sweden (L.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.020950DOI Listing
August 2016

Effect of apixaban on brain infarction and microbleeds: AVERROES-MRI assessment study.

Am Heart J 2016 Aug 17;178:145-50. Epub 2016 Apr 17.

Population Health Research Institute, McMaster University, and Hamilton Health Sciences, Hamilton, ON, Canada.

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http://dx.doi.org/10.1016/j.ahj.2016.03.019DOI Listing
August 2016

Toward Fairness in Data Sharing.

N Engl J Med 2016 Aug;375(5):405-7

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http://dx.doi.org/10.1056/NEJMp1605654DOI Listing
August 2016