Stuart A Scott

Stuart A Scott

UNVERIFIED PROFILE

Are you Stuart A Scott?   Register this Author

Register author
Stuart A Scott

Stuart A Scott

Publications by authors named "Stuart A Scott"

Are you Stuart A Scott?   Register this Author

82Publications

2431Reads

21Profile Views

Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles.

Hum Mutat 2019 11;40(11):e37-e51

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.23855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6810756PMC
November 2019

Characterization of Reference Materials for Genetic Testing of CYP2D6 Alleles: A GeT-RM Collaborative Project.

J Mol Diagn 2019 Nov 9;21(6):1034-1052. Epub 2019 Aug 9.

Informatics and Data Science Branch, Division of Laboratory Systems, Office of Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention, Atlanta, Georgia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2019.06.007DOI Listing
November 2019

A Call for Clear and Consistent Communications Regarding the Role of Pharmacogenetics in Antidepressant Pharmacotherapy.

Clin Pharmacol Ther 2019 Oct 30. Epub 2019 Oct 30.

Division of Clinical Pharmacology, Toxicology, & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City, Missouri, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1661DOI Listing
October 2019

Recommendations for Clinical CYP2C9 Genotyping Allele Selection: A Joint Recommendation of the Association for Molecular Pathology and College of American Pathologists.

J Mol Diagn 2019 Sep 8;21(5):746-755. Epub 2019 May 8.

The Pharmacogenomics (PGx) Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology and Laboratory Medicine and Department of Genetics, University of North Carolina, Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2019.04.003DOI Listing
September 2019

Interpreting and Implementing Clinical Pharmacogenetic Tests: Perspectives From Service Providers.

Clin Pharmacol Ther 2019 Aug 4;106(2):298-301. Epub 2019 Jun 4.

Sema4, a Mount Sinai Venture, Stamford, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1494DOI Listing
August 2019

Prenatal cytogenomic identification and molecular refinement of compound heterozygous STRC deletion breakpoints.

Mol Genet Genomic Med 2019 Aug 19;7(8):e806. Epub 2019 Jun 19.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mgg3.806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687617PMC
August 2019

Pharmacogene Variation Consortium Gene Introduction: NUDT15.

Clin Pharmacol Ther 2019 May 4;105(5):1091-1094. Epub 2018 Dec 4.

School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cpt.1268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465081PMC
May 2019

Familial inheritance of the 3q29 microdeletion syndrome: case report and review.

BMC Med Genomics 2019 03 18;12(1):51. Epub 2019 Mar 18.

Department of Pediatrics, Division of Clinical Genetics, New York-Presbyterian Morgan Stanley Children's Hospital, Columbia University Medical Center, New York, NY, 10032, USA.

View Article

Download full-text PDF

Source
https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s12920-019-0497-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421695PMC
March 2019

Integrated CYP2D6 interrogation for multiethnic copy number and tandem allele detection.

Pharmacogenomics 2019 01 6;20(1):9-20. Epub 2018 Dec 6.

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2018-0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563015PMC
January 2019

DNA Methylation Profiling Using Long-Read Single Molecule Real-Time Bisulfite Sequencing (SMRT-BS).

Methods Mol Biol 2017 ;1654:125-134

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1497, New York, NY, 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-7231-9_8DOI Listing
June 2018

Multi-ethnic SULT1A1 copy number profiling with multiplex ligation-dependent probe amplification.

Pharmacogenomics 2018 06 23;19(9):761-770. Epub 2018 May 23.

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2018-0047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021911PMC
June 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology.

J Mol Diagn 2018 05 21;20(3):269-276. Epub 2018 Feb 21.

Pharmacogenomics Working Group of the Clinical Practice Committee, Association for Molecular Pathology, Bethesda, Maryland; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2018.01.011DOI Listing
May 2018

Clinical determinants of clopidogrel responsiveness in a heterogeneous cohort of Puerto Rican Hispanics.

Ther Adv Cardiovasc Dis 2017 Sep 4;11(9):235-241. Epub 2017 Jul 4.

Pharmaceutical Sciences Department, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1753944717718718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555769PMC
September 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 07;49(8):1286

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng0817-1286cDOI Listing
July 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 Jun 17;49(6):946-952. Epub 2017 Apr 17.

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585859PMC
June 2017

Chromosomal Microarray Detection of Constitutional Copy Number Variation Using Saliva DNA.

J Mol Diagn 2017 05 18;19(3):397-403. Epub 2017 Mar 18.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2016.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417105PMC
May 2017

Maternal uniparental disomy of chromosome 15 and concomitant STRC and CATSPER2 deletion-mediated deafness-infertility syndrome.

Am J Med Genet A 2017 05 20;173(5):1436-1439. Epub 2017 Mar 20.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajmg.a.38154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397338PMC
May 2017

Sequencing the CYP2D6 gene: from variant allele discovery to clinical pharmacogenetic testing.

Pharmacogenomics 2017 May 4;18(7):673-685. Epub 2017 May 4.

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2017-0033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591463PMC
May 2017

The pharmacogenetic control of antiplatelet response: candidate genes and CYP2C19.

Expert Opin Drug Metab Toxicol 2015 14;11(10):1599-617. Epub 2015 Jul 14.

a 1 Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences , New York, NY, USA +1 212 241 3780 ; +1 212 241 0139 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17425255.2015.1068757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829114PMC
May 2016

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach.

Lancet Psychiatry 2016 Apr 23;3(4):350-7. Epub 2016 Feb 23.

Division of Psychiatric Genomics, Department of Psychiatry, New York, NY, USA; Institute for Genomics and Multiscale Biology, New York, NY, USA; Department of Genetics and Genomic Sciences, New York, NY, USA; Friedman Brain Institute, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2215-0366(15)00553-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982509PMC
April 2016

Long-Read Single Molecule Real-Time Full Gene Sequencing of Cytochrome P450-2D6.

Hum Mutat 2016 Mar 18;37(3):315-23. Epub 2015 Dec 18.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, 10029.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752389PMC
March 2016

Analytical Validation of a Personalized Medicine APOL1 Genotyping Assay for Nondiabetic Chronic Kidney Disease Risk Assessment.

J Mol Diagn 2016 Mar 7;18(2):260-6. Epub 2016 Jan 7.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816711PMC
March 2016

A 2.78-Mb duplication on chromosome 21q22.11 implicates candidate genes in the partial trisomy 21 phenotype.

NPJ Genom Med 2016 2;1. Epub 2016 Mar 2.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/npjgenmed.2016.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102301PMC
March 2016

Paroxysmal kinesigenic dyskinesia caused by 16p11.2 microdeletion.

Tremor Other Hyperkinet Mov (N Y) 2014 17;4:274. Epub 2014 Nov 17.

Movement Disorder Division, Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7916/D8N58K0QDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303604PMC
February 2015

CYP2C9 allelic variants and frequencies in a pediatric sickle cell disease cohort: implications for NSAIDs pharmacotherapy.

Clin Transl Sci 2014 Oct 29;7(5):396-401. Epub 2014 May 29.

College of Nursing, University of Cincinnati, Cincinnati, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/cts.12172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213284PMC
October 2014

Implementation and utilization of genetic testing in personalized medicine.

Pharmgenomics Pers Med 2014 13;7:227-40. Epub 2014 Aug 13.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/PGPM.S48887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157398PMC
September 2014

Life cycle assessment on microalgal biodiesel production using a hybrid cultivation system.

Bioresour Technol 2014 Jul 26;163:343-55. Epub 2014 Apr 26.

Department of Plant Sciences, University of Cambridge, Downing Site, Cambridge CB2 3EA, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biortech.2014.04.051DOI Listing
July 2014

Phycobilisome-Deficient Strains of Synechocystis sp. PCC 6803 Have Reduced Size and Require Carbon-Limiting Conditions to Exhibit Enhanced Productivity.

Plant Physiol 2014 Jun 23;165(2):705-714. Epub 2014 Apr 23.

Department of Biochemistry, University of Cambridge, Cambridge CB2 1QW, United Kingdom (D.J.L.-S., P.B., C.J.H.);Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 3RA, United Kingdom (J.S.D.);Department of Engineering, University of Cambridge, Cambridge CB2 1PZ, United Kingdom (S.A.S.); andDepartment of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, United Kingdom (A.G.S.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1104/pp.114.237206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044857PMC
June 2014

Kinetic modelling of growth and storage molecule production in microalgae under mixotrophic and autotrophic conditions.

Bioresour Technol 2014 Apr 22;157:293-304. Epub 2014 Jan 22.

Department of Plant Sciences, University of Cambridge, Downing Site, Cambridge CB2 3EA, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biortech.2014.01.032DOI Listing
April 2014

Warfarin pharmacogenetic trials: is there a future for pharmacogenetic-guided dosing?

Pharmacogenomics 2014 Apr;15(6):719-22

Department of Genetics & Genomic Sciences, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1497, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.14.18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110075PMC
April 2014

An Ashkenazi Jewish SMN1 haplotype specific to duplication alleles improves pan-ethnic carrier screening for spinal muscular atrophy.

Genet Med 2014 Feb 20;16(2):149-56. Epub 2013 Jun 20.

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine of New York University, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2013.84DOI Listing
February 2014

Antiplatelet drug interactions with proton pump inhibitors.

Expert Opin Drug Metab Toxicol 2014 Feb 9;10(2):175-89. Epub 2013 Nov 9.

Icahn School of Medicine at Mount Sinai, Department of Genetics and Genomic Sciences , One Gustave L. Levy Place, Box 1497, New York, NY 10029 , USA +1 212 241 3780 ; +1 212 241 0139 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17425255.2014.856883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110685PMC
February 2014

Adapting Data Processing To Compare Model and Experiment Accurately: A Discrete Element Model and Magnetic Resonance Measurements of a 3D Cylindrical Fluidized Bed.

Ind Eng Chem Res 2013 Dec 12;52(50):18085-18094. Epub 2013 Nov 12.

Department of Chemical Engineering and Biotechnology, University of Cambridge , New Museums Site, Pembroke Street, Cambridge CB2 3RA, U.K.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ie401896xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901572PMC
December 2013

An allele-specific PCR system for rapid detection and discrimination of the CYP2C19∗4A, ∗4B, and ∗17 alleles: implications for clopidogrel response testing.

J Mol Diagn 2013 Nov 5;15(6):783-9. Epub 2013 Sep 5.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2013.06.004DOI Listing
November 2013

Warfarin pharmacogenetics: a controlled dose-response study in healthy subjects.

Vasc Med 2013 Oct 12;18(5):290-7. Epub 2013 Sep 12.

Vascular Medicine Section, The Zena and Michael A Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1358863X13503193DOI Listing
October 2013

Frequency of the cholesteryl ester storage disease common LIPA E8SJM mutation (c.894G>A) in various racial and ethnic groups.

Hepatology 2013 Sep 29;58(3):958-65. Epub 2013 Jul 29.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.26327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690149PMC
September 2013

Laboratory testing of CYP2D6 alleles in relation to tamoxifen therapy.

Genet Med 2012 Dec 6;14(12):990-1000. Epub 2012 Sep 6.

Department of Pathology, University of Utah School of Medicine, Molecular Genetics, ARUP Laboratories, Salt Lake City, Utah, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/gim.2012.108DOI Listing
December 2012

Treatment of Phaeodactylum tricornutum cells with papain facilitates lipid extraction.

J Biotechnol 2012 Nov 10;162(1):40-9. Epub 2012 Jul 10.

Department of Plant Sciences, University of Cambridge, Downing Street, Cambridge CB2 3EA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbiotec.2012.06.033DOI Listing
November 2012

Pharmacokinetics of dasatinib for Philadelphia-positive acute lymphocytic leukemia with acquired T315I mutation.

J Hematol Oncol 2012 May 15;5:23. Epub 2012 May 15.

Dept. of Hematology Nephrology and Rheumatology, Akita Univ. Graduate School of Medicine, Akita, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8722-5-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3409074PMC
May 2012

PharmGKB summary: very important pharmacogene information for cytochrome P450, family 2, subfamily C, polypeptide 19.

Pharmacogenet Genomics 2012 Feb;22(2):159-65

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0b013e32834d4962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349992PMC
February 2012

Copy number variation and warfarin dosing: evaluation of CYP2C9, VKORC1, CYP4F2, GGCX and CALU.

Pharmacogenomics 2012 Feb 21;13(3):297-307. Epub 2011 Dec 21.

Department of Genetics & Genomic Sciences, Box 1497, Mount Sinai School of Medicine, 1428 Madison Avenue, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.11.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292047PMC
February 2012

Personalizing medicine with clinical pharmacogenetics.

Authors:
Stuart A Scott

Genet Med 2011 Dec;13(12):987-95

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/GIM.0b013e318238b38cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290900PMC
December 2011

CYP2C19 but not PON1 genetic variants influence clopidogrel pharmacokinetics, pharmacodynamics, and clinical efficacy in post-myocardial infarction patients.

Circ Cardiovasc Interv 2011 Oct 4;4(5):422-8. Epub 2011 Oct 4.

Université Pierre et Marie Curie-Paris 6, INSERM UMR S 956, Pharmacology Department, Pitié-Salpêtrière University Hospital, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCINTERVENTIONS.111.963025DOI Listing
October 2011

Experience with carrier screening and prenatal diagnosis for 16 Ashkenazi Jewish genetic diseases.

Hum Mutat 2010 Nov;31(11):1240-50

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine of New York University, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.21327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970726PMC
November 2010

Large inverted repeats within Xp11.2 are present at the breakpoints of isodicentric X chromosomes in Turner syndrome.

Hum Mol Genet 2010 Sep 22;19(17):3383-93. Epub 2010 Jun 22.

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine of New York University, New York 10029, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
Publisher Site
http://dx.doi.org/10.1093/hmg/ddq250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916707PMC
September 2010

Biodiesel from algae: challenges and prospects.

Curr Opin Biotechnol 2010 Jun 17;21(3):277-86. Epub 2010 Apr 17.

Department of Engineering, University of Cambridge, Trumpington Street, Cambridge CB2 1PZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.copbio.2010.03.005DOI Listing
June 2010

Combined CYP2C9, VKORC1 and CYP4F2 frequencies among racial and ethnic groups.

Pharmacogenomics 2010 Jun;11(6):781-91

Department of Genetics & Genomic Sciences, Box 1498, Mount Sinai School of Medicine of New York University, Fifth Avenue at 100th Street, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.10.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904527PMC
June 2010

Detection of low-level mosaicism and placental mosaicism by oligonucleotide array comparative genomic hybridization.

Genet Med 2010 Feb;12(2):85-92

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine of New York University, New York City, New York 10029, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/doifinder/10.1097/GIM.0b013e3181cc75d0
Publisher Site
http://dx.doi.org/10.1097/GIM.0b013e3181cc75d0DOI Listing
February 2010

CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.

Pharmacogenomics 2009 Aug;10(8):1243-55

Department of Genetics & Genomic Sciences, Mount Sinai School of Medicine of New York University, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs.09.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737687PMC
August 2009

Itraconazole oral solution enhanced vincristine neurotoxicity in five patients with malignant lymphoma.

Intern Med 2008 1;47(7):651-3. Epub 2008 Apr 1.

Division of Hematology and Oncology, Department of Internal Medicine, Akita University School of Medicine, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2169/internalmedicine.47.0701DOI Listing
June 2008

Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.

Am J Hum Genet 2008 Feb 17;82(2):495-500. Epub 2008 Jan 17.

Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine of New York University, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2007.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427171PMC
February 2008

CYP2C9, CYP2C19 and CYP2D6 allele frequencies in the Ashkenazi Jewish population.

Pharmacogenomics 2007 Jul;8(7):721-30

Mount Sinai School of Medicine of New York University, Department of Genetics and Genomic Sciences, Box 1498, Fifth Avenue at 100th Street, New York, NY 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/14622416.8.7.721DOI Listing
July 2007

Methylation status of cyclin-dependent kinase inhibitor genes within the transforming growth factor beta pathway in human T-cell lymphoblastic lymphoma/leukemia.

Leuk Res 2004 Dec;28(12):1293-301

Department of Pathology, Saskatoon Cancer Centre, Royal University Hospital, University of Saskatchewan, 103 Hospital Drive, Saskatoon, Saskatchewan, S7N 0W8, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2004.03.019DOI Listing
December 2004