Publications by authors named "Stian Knappskog"

86Publications

Assessment of tumor suppressor promoter methylation in healthy individuals.

Clin Epigenetics 2020 Aug 28;12(1):131. Epub 2020 Aug 28.

K.G. Jebsen Center for Genome Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1186/s13148-020-00920-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7455917PMC
August 2020

Golgi-Localized PAQR4 Mediates Antiapoptotic Ceramidase Activity in Breast Cancer.

Cancer Res 2020 Jun 14;80(11):2163-2174. Epub 2020 Apr 14.

Department of Biomedicine, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-3177DOI Listing
June 2020

Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors.

Int J Mol Sci 2019 Aug 29;20(17). Epub 2019 Aug 29.

Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009 Bergen, Norway.

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http://dx.doi.org/10.3390/ijms20174235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747502PMC
August 2019

Constitutional Mosaic Epimutations - a hidden cause of cancer?

Cell Stress 2019 Mar 22;3(4):118-135. Epub 2019 Mar 22.

K.G.Jebsen Center for Genome Directed Cancer Therapy, Department of Clinical Science, University of Bergen, Norway.

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http://dx.doi.org/10.15698/cst2019.04.183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551830PMC
March 2019

Influence of p53 Isoform Expression on Survival in High-Grade Serous Ovarian Cancers.

Sci Rep 2019 03 27;9(1):5244. Epub 2019 Mar 27.

Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, 5020, Bergen, Norway.

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http://dx.doi.org/10.1038/s41598-019-41706-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437169PMC
March 2019

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2019 02;566(7742):E1

Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1SA, UK.

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http://www.nature.com/articles/s41586-019-0883-2
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http://dx.doi.org/10.1038/s41586-019-0883-2DOI Listing
February 2019

Introducing nano-scale quantitative polymerase chain reaction.

Biochem Biophys Res Commun 2018 12 2;506(4):923-926. Epub 2018 Nov 2.

Department of Biomedicine, University of Bergen, Norway; Department of Oncology, Haukeland University Hospital, Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.10.111DOI Listing
December 2018

BRCA1 methylation in newborns: genetic disposition, maternal transfer, environmental influence, or by chance only?

Clin Epigenetics 2018 10 22;10(1):128. Epub 2018 Oct 22.

Department of Clinical Science, University of Bergen, Bergen, Norway.

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https://clinicalepigeneticsjournal.biomedcentral.com/article
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http://dx.doi.org/10.1186/s13148-018-0566-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196557PMC
October 2018

High expression of the p53 isoform γ is associated with reduced progression-free survival in uterine serous carcinoma.

BMC Cancer 2018 Jun 25;18(1):684. Epub 2018 Jun 25.

Centre for Cancer Biomarkers (CCBIO), Department of Clinical Science, Precision Oncology Research Group, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1186/s12885-018-4591-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019524PMC
June 2018

APOBEC3A/B deletion polymorphism and cancer risk.

Carcinogenesis 2018 02;39(2):118-124

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1093/carcin/bgx131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862322PMC
February 2018

The Functional Roles of the MDM2 Splice Variants P2-MDM2-10 and MDM2-∆5 in Breast Cancer Cells.

Transl Oncol 2017 Oct 29;10(5):806-817. Epub 2017 Aug 29.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Oncology, Haukeland University Hospital, Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2017.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576977PMC
October 2017

Effects of concomitant inactivation of p53 and pRb on response to doxorubicin treatment in breast cancer cell lines.

Cell Death Discov 2017 22;3:17026. Epub 2017 May 22.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1038/cddiscovery.2017.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439126PMC
May 2017

Tumor cells interact with red blood cells via galectin-4 - a short report.

Cell Oncol (Dordr) 2017 Aug 14;40(4):401-409. Epub 2017 Mar 14.

Functional Genome Analysis, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s13402-017-0317-9DOI Listing
August 2017

High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function.

Breast Cancer Res Treat 2017 May 17;163(1):177-190. Epub 2017 Feb 17.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1007/s10549-017-4160-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387035PMC
May 2017

MDM2 promoter polymorphism del1518 (rs3730485) and its impact on endometrial and ovarian cancer risk.

BMC Cancer 2017 02 3;17(1):97. Epub 2017 Feb 3.

Section of Oncology, Department of Clinical Science, University of Bergen, Haukeland University Hospiltal, Jonas Lies veg 87, 5021, Bergen, Norway.

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http://dx.doi.org/10.1186/s12885-017-3094-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291962PMC
February 2017

Prevalence of the R95* germline mutation.

Hered Cancer Clin Pract 2016 27;14:19. Epub 2016 Sep 27.

Section of Oncology, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway ; Department of Oncology, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1186/s13053-016-0059-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039915PMC
September 2016

MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer.

Sci Rep 2016 09 14;6:33153. Epub 2016 Sep 14.

Section of Oncology, Department of Clinical Science, University of Bergen, 5020 Bergen, Norway.

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http://dx.doi.org/10.1038/srep33153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022009PMC
September 2016

Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers.

J Steroid Biochem Mol Biol 2017 01 22;165(Pt B):228-235. Epub 2016 Jun 22.

Department of Clinical Science, University of Bergen, 5021 Bergen, Norway; Hormone Laboratory, Haukeland University Hospital, 5021 Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2016.06.011DOI Listing
January 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

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http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Nature 2016 06 2;534(7605):47-54. Epub 2016 May 2.

Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature17676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910866PMC
June 2016

Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.

Mutagenesis 2016 07 16;31(4):401-8. Epub 2015 Dec 16.

Division of Functional Genome Analysis, Deutsche Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1093/mutage/gev086DOI Listing
July 2016

MDM4 SNP34091 (rs4245739) and its effect on breast-, colon-, lung-, and prostate cancer risk.

Cancer Med 2015 Dec 16;4(12):1901-7. Epub 2015 Oct 16.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1002/cam4.555DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123711PMC
December 2015

Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer.

PLoS One 2015 6;10(8):e0134351. Epub 2015 Aug 6.

Hormone Laboratory, Haukeland University Hospital, Bergen, Norway; Department of Clinical Science, University of Bergen, Bergen, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134351PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527840PMC
May 2016

Influence of MDM2 SNP309 and SNP285 status on the risk of cancer in the breast, prostate, lung and colon.

Int J Cancer 2015 Jul 10;137(1):96-103. Epub 2014 Dec 10.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Oncology, Haukeland University Hospital, Bergen, Norway.

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http://doi.wiley.com/10.1002/ijc.29358
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http://dx.doi.org/10.1002/ijc.29358DOI Listing
July 2015

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Science 2014 Aug;345(6196):1251343

Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, UK.

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http://dx.doi.org/10.1126/science.1251343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380235PMC
August 2014

MDM2 SNP309 and risk of endometrial cancer.

Tumour Biol 2014 Aug 26;35(8):7285-6. Epub 2014 Jun 26.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway,

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http://dx.doi.org/10.1007/s13277-014-2244-yDOI Listing
August 2014

TP53 status predicts long-term survival in locally advanced breast cancer after primary chemotherapy.

Acta Oncol 2014 Oct 9;53(10):1347-55. Epub 2014 Jun 9.

Section of Oncology, Department of Clinical Science, University of Bergen , Bergen , Norway.

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http://dx.doi.org/10.3109/0284186X.2014.922215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245178PMC
October 2014

MDM2 SNP309 and risk of cervical cancer.

Tumour Biol 2014 Jul 17;35(7):6185-6. Epub 2014 Apr 17.

Section of Oncology, Department of Clinical Science, University of Bergen, Bergen, Norway,

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http://dx.doi.org/10.1007/s13277-014-1910-4DOI Listing
July 2014

Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue.

J Steroid Biochem Mol Biol 2014 Sep 18;143:192-8. Epub 2014 Feb 18.

Section of Oncology, Department of Clinical Science, University of Bergen, Norway; Department of Oncology, Haukeland University Hospital, Bergen, Norway. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2014.02.003DOI Listing
September 2014

Signatures of mutational processes in human cancer.

Nature 2013 Aug 14;500(7463):415-21. Epub 2013 Aug 14.

Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SA, UK.

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http://dx.doi.org/10.1038/nature12477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776390PMC
August 2013

MDM2 SNP309 and risk of endometrial cancer.

Pol J Pathol 2013 Apr;64(1):69-70

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http://dx.doi.org/10.5114/pjp.2013.34607DOI Listing
April 2013

Functional characterisation of p53 mutants identified in breast cancers with suboptimal responses to anthracyclines or mitomycin.

Biochim Biophys Acta 2013 Mar;1830(3):2790-7

Section of Oncology, Institute of Medicine, University of Bergen, Jonas Lies vei 65, N-5021 Bergen, Norway.

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http://dx.doi.org/10.1016/j.bbagen.2012.12.004DOI Listing
March 2013

Chemosensitivity and p53; new tricks by an old dog.

Breast Cancer Res 2012 Nov 6;14(6):325. Epub 2012 Nov 6.

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http://dx.doi.org/10.1186/bcr3326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053121PMC
November 2012

Effect of the MDM2 promoter polymorphisms SNP309T>G and SNP285G>C on the risk of ovarian cancer in BRCA1 mutation carriers.

BMC Cancer 2012 Oct 5;12:454. Epub 2012 Oct 5.

Department of Medical Genetics, Oslo University Hospital – The Norwegian Radium Hospital, Oslo, Norway.

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http://dx.doi.org/10.1186/1471-2407-12-454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3519699PMC
October 2012

Re: Murine double minute 2 promoter SNP309 polymorphism and prostate cancer risk: a meta-analysis.

Authors:
Stian Knappskog

Int J Urol 2012 Oct 30;19(10):966. Epub 2012 Jul 30.

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http://dx.doi.org/10.1111/j.1442-2042.2012.03108.xDOI Listing
October 2012

P53 and its molecular basis to chemoresistance in breast cancer.

Expert Opin Ther Targets 2012 Mar 8;16 Suppl 1:S23-30. Epub 2012 Feb 8.

Section of Oncology, Institute of Medicine, University of Bergen, 5020 Bergen, Norway.

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http://dx.doi.org/10.1517/14728222.2011.640322DOI Listing
March 2012

Effects of the MDM2 promoter SNP285 and SNP309 on Sp1 transcription factor binding and cancer risk.

Transcription 2011 Sep-Oct;2(5):207-10

Section of Oncology, Institute of Medicine, University of Bergen; Bergen, Norway.

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http://dx.doi.org/10.4161/trns.2.5.16813DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265776PMC
June 2012

Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women.

J Steroid Biochem Mol Biol 2012 Jan 16;128(1-2):69-75. Epub 2011 Sep 16.

Section of Oncology, Institute of Medicine, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1016/j.jsbmb.2011.08.015DOI Listing
January 2012

Exploring breast cancer estrogen disposition: the basis for endocrine manipulation.

Clin Cancer Res 2011 Aug 26;17(15):4948-58. Epub 2011 Jul 26.

Section of Oncology, Institute of Medicine, University of Bergen, and Department of Oncology, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0043DOI Listing
August 2011

Clinical effect of temozolomide-based chemotherapy in poorly differentiated endocrine carcinoma after progression on first-line chemotherapy.

Cancer 2011 Oct 31;117(20):4617-22. Epub 2011 Mar 31.

Department of Medical Sciences, Endocrine Oncology, Uppsala University, Sweden.

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http://dx.doi.org/10.1002/cncr.26124DOI Listing
October 2011

Recent data on intratumor estrogens in breast cancer.

Steroids 2011 Jul 31;76(8):786-91. Epub 2011 Mar 31.

Section of Oncology, Institute of Medicine, University of Bergen, Norway.

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http://dx.doi.org/10.1016/j.steroids.2011.02.040DOI Listing
July 2011

MDM2 promoter SNP285 and SNP309; phylogeny and impact on cancer risk.

Oncotarget 2011 Mar;2(3):251-8

Section of Oncology, Institute of Medicine, University of Bergen, 5020 Bergen, Norway.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260817PMC
http://dx.doi.org/10.18632/oncotarget.243DOI Listing
March 2011

Alterations of the retinoblastoma gene in metastatic breast cancer.

Clin Exp Metastasis 2011 Mar 21;28(3):319-26. Epub 2011 Jan 21.

Section of Oncology, Institute of Medicine, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1007/s10585-011-9375-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040352PMC
March 2011

New doctorial cancer research: germline genetic alterations affecting CDKN2A, MDM2, and CDKN1A in melanoma and breast cancer patients.

Authors:
Stian Knappskog

Crit Rev Oncog 2007 Dec;13(3):261-2; discussion 263

Section of Oncology, Institute of Medicine, University of Bergen.

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http://dx.doi.org/10.1615/critrevoncog.v13.i3.30DOI Listing
December 2007

Mutations and polymorphisms of the p21B transcript in breast cancer.

Int J Cancer 2007 Aug;121(4):908-10

Department of Molecular Biology, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1002/ijc.22777DOI Listing
August 2007

A novel type of deletion in the CDKN2A gene identified in a melanoma-prone family.

Genes Chromosomes Cancer 2006 Dec;45(12):1155-63

Department of Medicine, Section of Oncology, Haukeland University Hospital, N-5021 Bergen, Norway.

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http://dx.doi.org/10.1002/gcc.20379DOI Listing
December 2006