Stewart Bates

Stewart Bates

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Stewart Bates

Stewart Bates

Publications by authors named "Stewart Bates"

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19Publications

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Biomarkers for severe eosinophilic asthma.

J Allergy Clin Immunol 2017 Dec;140(6):1509-1518

Respiratory Medicine Unit and Oxford Respiratory BRC, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2017.10.005DOI Listing
December 2017

Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort.

PLoS One 2014 29;9(9):e107381. Epub 2014 Sep 29.

Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107381PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179270PMC
June 2015

Gene expression changes caused by the p38 MAPK inhibitor dilmapimod in COPD patients: analysis of blood and sputum samples from a randomized, placebo-controlled clinical trial.

Pharmacol Res Perspect 2015 Feb 9;3(1):e00094. Epub 2014 Dec 9.

University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundations Trust Manchester, United Kingdom.

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http://dx.doi.org/10.1002/prp2.94DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317226PMC
February 2015

Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study.

Acta Neuropathol Commun 2014 Dec 14;2:165. Epub 2014 Dec 14.

Département des Maladies du Système Nerveux, APHP, Reseau SLA IDF Groupe Hospitalier Pitié-Salpêtrière, Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Laboratoire d'Imagerie Biomédicale (LIB), Paris, F-75005, France.

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http://dx.doi.org/10.1186/s40478-014-0165-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297389PMC
December 2014

Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1G93A mouse model of Amyotrophic lateral sclerosis.

Hum Mol Genet 2014 Aug 25;23(16):4187-200. Epub 2014 Mar 25.

Sobell Department of Motor Neuroscience and Movement Disorders, MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK

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http://dx.doi.org/10.1093/hmg/ddu136DOI Listing
August 2014

The role of gene expression profiling in drug discovery.

Authors:
Stewart Bates

Curr Opin Pharmacol 2011 Oct;11(5):549-56

Biomarker Discovery, Biopharmaceutical R&D Unit, GlaxoSmithKline, Stevenage, SG1 2NY, Hertfordshire, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S14714892110008
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http://dx.doi.org/10.1016/j.coph.2011.06.009DOI Listing
October 2011

Induced sputum genes associated with spirometric and radiological disease severity in COPD ex-smokers.

Thorax 2011 Jun 24;66(6):489-95. Epub 2011 Mar 24.

University of Manchester, Medicines Evaluation Unit, University Hospital of South Manchester Foundation Trust, Manchester M23 9LT, UK.

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http://dx.doi.org/10.1136/thx.2010.153767DOI Listing
June 2011

Progress towards personalized medicine.

Authors:
Stewart Bates

Drug Discov Today 2010 Feb 13;15(3-4):115-20. Epub 2009 Nov 13.

Director Biomarker Discovery, Biopharm R&D, GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S135964460900373
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http://dx.doi.org/10.1016/j.drudis.2009.11.001DOI Listing
February 2010

Characterization of the human HCN1 channel and its inhibition by capsazepine.

Br J Pharmacol 2004 Oct 6;143(3):411-21. Epub 2004 Sep 6.

Neurology & GI CEDD, GlaxoSmithKline, New Frontiers Science Park North, Third Avenue, Harlow, Essex CM19 5AW.

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http://dx.doi.org/10.1038/sj.bjp.0705945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1575350PMC
October 2004

INK4a-deficient human diploid fibroblasts are resistant to RAS-induced senescence.

EMBO J 2002 Jun;21(12):2936-45

Molecular Oncology and Human Cytogenetics Laboratories, Cancer Research UK London Research Institute, Lincolns Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1093/emboj/cdf289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126048PMC
June 2002