Publications by authors named "Steven X Hou"

41Publications

Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice.

Nat Commun 2020 01 10;11(1):220. Epub 2020 Jan 10.

The Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD, 21702, USA.

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http://dx.doi.org/10.1038/s41467-019-14046-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954189PMC
January 2020

Cancer Stem Cells and Stem Cell Tumors in Drosophila.

Adv Exp Med Biol 2019 ;1167:175-190

The Basic Research Laboratory, Center for Cancer Research, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-3-030-23629-8_10DOI Listing
September 2019

Corrigendum to "The PDZ-GEF Gef26 regulates synapse development and function via FasII and Rap 1 at the Drosophila neuromuscular junction" [Exp. Cell Res. 374 (2019) 342-352].

Exp Cell Res 2019 Aug 10;381(1):164. Epub 2019 May 10.

The Key Laboratory of Development Genes and Human Diseases, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing, 210096, China. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2019.04.024DOI Listing
August 2019

The PDZ-GEF Gef26 regulates synapse development and function via FasII and Rap1 at the Drosophila neuromuscular junction.

Exp Cell Res 2019 01 13;374(2):342-352. Epub 2018 Dec 13.

The Key Laboratory of Development Genes and Human Diseases, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing 210096, China. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2018.12.008DOI Listing
January 2019

Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells.

Oncotarget 2017 Oct 28;8(48):83602-83618. Epub 2017 Jun 28.

The Basic Research Laboratory, National Cancer Institute, National Institutes of Health Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.18632/oncotarget.18787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663539PMC
October 2017

The cell polarity protein Scrib functions as a tumor suppressor in liver cancer.

Oncotarget 2017 Apr;8(16):26515-26531

Department of Biochemistry and Molecular Biology, Molecular Oncology & Biomarkers Program, Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA.

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http://dx.doi.org/10.18632/oncotarget.15713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432276PMC
April 2017

The SWI/SNF Complex Protein Snr1 Is a Tumor Suppressor in Imaginal Tissues.

Cancer Res 2017 02 6;77(4):862-873. Epub 2016 Dec 6.

Department of Biological Science, Florida State University, Tallahassee, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0963DOI Listing
February 2017

The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila.

Nature 2016 Oct 28;538(7623):109-113. Epub 2016 Sep 28.

The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/nature19788DOI Listing
October 2016

Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila.

Nat Commun 2016 08 3;7:12149. Epub 2016 Aug 3.

Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health, 1050 Boyles Street, Building 560, Room 12-70, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/ncomms12149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976209PMC
August 2016

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis.

Nat Commun 2016 Jan 21;7:10473. Epub 2016 Jan 21.

The Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1038/ncomms10473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736159PMC
January 2016

The Nuclear Matrix Protein Megator Regulates Stem Cell Asymmetric Division through the Mitotic Checkpoint Complex in Drosophila Testes.

PLoS Genet 2015 Dec 29;11(12):e1005750. Epub 2015 Dec 29.

The Basic Research Laboratory, National Cancer Institute, National Institutes of Health, Frederick, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703072PMC
December 2015

Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.

Cell Rep 2015 Feb 19;10(7):1226-38. Epub 2015 Feb 19.

Basic Research Laboratory, National Cancer Institute at Frederick, NIH, Frederick, MD 21702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.01.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420031PMC
February 2015

Enteroendocrine cells are generated from stem cells through a distinct progenitor in the adult Drosophila posterior midgut.

Development 2015 Feb;142(4):644-53

Basic Research Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD 21701, USA

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http://dx.doi.org/10.1242/dev.113357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325374PMC
February 2015

The Osa-containing SWI/SNF chromatin-remodeling complex regulates stem cell commitment in the adult Drosophila intestine.

Development 2013 Sep;140(17):3532-40

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1242/dev.096891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742141PMC
September 2013

Stem cells in the Drosophila digestive system.

Adv Exp Med Biol 2013 ;786:63-78

The Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1007/978-94-007-6621-1_5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571253PMC
September 2013

Broad relays hormone signals to regulate stem cell differentiation in Drosophila midgut during metamorphosis.

Development 2012 Nov;139(21):3917-25

The Mouse Cancer Genetics Program, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1242/dev.083030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472594PMC
November 2012

Generation and staining of intestinal stem cell lineage in adult midgut.

Methods Mol Biol 2012 ;879:47-69

Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-61779-815-3_4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461621PMC
September 2012

Kidney stem cells found in adult zebrafish.

Cell Stem Cell 2011 Mar;8(3):247-9

The Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/j.stem.2011.02.008DOI Listing
March 2011

Spermatogonial stem cells, infertility and testicular cancer.

J Cell Mol Med 2011 Mar;15(3):468-83

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1111/j.1582-4934.2010.01242.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3064728PMC
March 2011

Characterization of midgut stem cell- and enteroblast-specific Gal4 lines in drosophila.

Genesis 2010 Oct;48(10):607-11

Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland, USA.

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http://doi.wiley.com/10.1002/dvg.20661
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http://dx.doi.org/10.1002/dvg.20661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958251PMC
October 2010

RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.

Blood 2010 Oct 1;116(16):2921-31. Epub 2010 Jul 1.

Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD 21702-1201, USA.

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http://dx.doi.org/10.1182/blood-2010-01-262964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974602PMC
October 2010

Intestinal stem cell asymmetric division in the Drosophila posterior midgut.

Authors:
Steven X Hou

J Cell Physiol 2010 Sep;224(3):581-4

National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1002/jcp.22194DOI Listing
September 2010

Tumor suppressors Sav/Scrib and oncogene Ras regulate stem-cell transformation in adult Drosophila malpighian tubules.

J Cell Physiol 2010 Sep;224(3):766-74

Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1002/jcp.22179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391499PMC
September 2010

Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling.

J Cell Physiol 2010 May;223(2):500-10

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1002/jcp.22073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894562PMC
May 2010

JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells.

J Cell Biochem 2010 Apr;109(5):992-9

The Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1002/jcb.22482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893559PMC
April 2010

Regulation of intestinal stem cells in mammals and Drosophila.

J Cell Physiol 2010 Jan;222(1):33-7

The Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1002/jcp.21928DOI Listing
January 2010

Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster.

J Exp Biol 2009 Feb;212(Pt 3):413-23

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute, MD 21702, USA.

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http://dx.doi.org/10.1242/jeb.024216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2699409PMC
February 2009

Germline stem cells. Preface.

Methods Mol Biol 2008 ;450

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-60327-214-8DOI Listing
May 2008

The adult Drosophila malpighian tubules are maintained by multipotent stem cells.

Cell Stem Cell 2007 Aug;1(2):191-203

The Mouse Cancer Genetics Program, National Cancer Institute at Frederick, National Institutes of Health, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/j.stem.2007.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2040309PMC
August 2007

Genetic tools used for cell lineage tracing and gene manipulation in Drosophila germline stem cells.

Methods Mol Biol 2008 ;450:61-70

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-60327-214-8_4DOI Listing
May 2008

Immunohistological techniques for studying the Drosophila male germline stem cell.

Methods Mol Biol 2008 ;450:45-59

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD, USA.

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http://dx.doi.org/10.1007/978-1-60327-214-8_3DOI Listing
May 2008

Lessons learned about adult kidney stem cells from the malpighian tubules of Drosophila.

J Am Soc Nephrol 2008 Apr 20;19(4):660-6. Epub 2008 Feb 20.

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://www.jasn.org/cgi/doi/10.1681/ASN.2007121307
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http://dx.doi.org/10.1681/ASN.2007121307DOI Listing
April 2008

Rap-GEF/Rap signaling restricts the formation of supernumerary spermathecae in Drosophila melanogaster.

Dev Growth Differ 2006 Apr;48(3):169-75

Mouse Cancer Genetics Program, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1111/j.1440-169X.2006.00854.xDOI Listing
April 2006

Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis.

Dev Cell 2006 Jan;10(1):117-26

The Laboratory of Immunobiology, National Institutes of Health National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1016/j.devcel.2005.11.004DOI Listing
January 2006

JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila.

Cell Res 2005 Jan;15(1):1-5

The Laboratory of Immunobiology,National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1038/sj.cr.7290255DOI Listing
January 2005

A P-element insertion screen identified mutations in 455 novel essential genes in Drosophila.

Genetics 2003 Jan;163(1):195-201

The Laboratory of Immunobiology, National Institutes of Health, National Cancer Institute, Frederick, Maryland 21702-1201, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462436PMC
January 2003

Cyclin D-Cdk4 and cyclin E-Cdk2 regulate the Jak/STAT signal transduction pathway in Drosophila.

Dev Cell 2003 Feb;4(2):179-90

Laboratory of Immunobiology, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1016/s1534-5807(03)00024-8DOI Listing
February 2003

The Jak/STAT pathway in model organisms: emerging roles in cell movement.

Dev Cell 2002 Dec;3(6):765-78

The Laboratory of Immunobiology, National Cancer Institute at Frederick, Building 560, Room 12-70, MD 21702, USA.

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http://perrimon.med.harvard.edu/papers/houdevcell.pdf
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http://dx.doi.org/10.1016/s1534-5807(02)00376-3DOI Listing
December 2002

CKA, a novel multidomain protein, regulates the JUN N-terminal kinase signal transduction pathway in Drosophila.

Mol Cell Biol 2002 Mar;22(6):1792-803

The Laboratory of Immunobiology, National Institutes of Health, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC135602PMC
http://dx.doi.org/10.1128/mcb.22.6.1792-1803.2002DOI Listing
March 2002

mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family.

Genes Dev 2002 Feb;16(3):388-98

The Laboratory of Immunobiology, National Institutes of Health, National Cancer Institute at Frederick, Frederick, Maryland 21702, USA.

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http://dx.doi.org/10.1101/gad.955202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155335PMC
February 2002