Publications by authors named "Steven R Brant"

100Publications

Common and rare variant prediction and penetrance of IBD in a large, multi-ethnic, health system-based biobank cohort.

Gastroenterology 2020 Dec 24. Epub 2020 Dec 24.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA. Electronic address:

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December 2020

Role of telomere shortening in anticipation of inflammatory bowel disease.

World J Gastrointest Pharmacol Ther 2020 Sep;11(4):69-78

Division of Gastroenterology and Hepatology, Department of Medicine, Rutgers-Robert Wood Johnson Medical School, NJ, 08901, United States.

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September 2020

Sestrin3 enhances macrophage-mediated generation of T helper 1 and T helper 17 cells in a mouse colitis model.

Int Immunol 2020 05;32(6):421-432

Department of Gastroenterology, Zhongnan Hospital of Wuhan University, Hubei Clinical Center and Key Laboratory for Intestinal and Colorectal Diseases, Wuhan, China.

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May 2020

Sustained Resolution of Multifocal Low-Grade Dysplasia in Ulcerative Colitis.

ACG Case Rep J 2019 Sep 21;6(9):e00178. Epub 2019 Aug 21.

Crohns and Colitis Center of New Jersey, Division of Gastroenterology and Hepatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.

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September 2019

Deletion of IL-6 Exacerbates Colitis and Induces Systemic Inflammation in IL-10-Deficient Mice.

J Crohns Colitis 2020 Jul;14(6):831-840

Division of Gastroenterology, Department of Medicine, Johns Hopkins Medicine, Baltimore, MD, USA.

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July 2020

Levels of Vitamin D Are Low After Crohn's Disease Is Established But Not Before.

Clin Gastroenterol Hepatol 2020 Jul 4;18(8):1769-1776.e1. Epub 2019 Oct 4.

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Division of Gastroenterology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; Division of Gastroenterology and Hepatology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, and Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers University, New Brunswick, New Jersey. Electronic address:

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July 2020

miR-206 as a Biomarker for Response to Mesalamine Treatment in Ulcerative Colitis.

Inflamm Bowel Dis 2019 01;25(1):78-84

Division of Gastroenterology, Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA.

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January 2019

An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis.

Sci Transl Med 2018 06;10(444)

Mucosal Immunity Section, Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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June 2018

Smoking and Inflammatory Bowel Disease: A Comparison of China, India, and the USA.

Dig Dis Sci 2018 10 4;63(10):2703-2713. Epub 2018 Jun 4.

Division of Gastroenterology and Hepatology, Gastrointestinal Epidemiology Research Center, Johns Hopkins University, 600 N Wolfe St, Blalock 449, Baltimore, MD, 21287, USA.

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October 2018

Anesthesia Assistance in Outpatient Colonoscopy.

Gastroenterology 2018 06 7;154(8):2278-2279. Epub 2018 May 7.

Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.

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June 2018

Nearly a Third of High-Grade Dysplasia and Colorectal Cancer Is Undetected in Patients with Inflammatory Bowel Disease.

Dig Dis Sci 2017 12 19;62(12):3586-3593. Epub 2017 Jun 19.

Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, 4119B Bioinformatics Building, 130 Mason Farm Road, Chapel Hill, NC, 27599-7080, USA.

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December 2017

Routine Pouchoscopy Prior to Ileostomy Takedown May Not Be Necessary in Patients with Chronic Ulcerative Colitis.

Dig Dis 2018 9;36(1):72-77. Epub 2017 Jun 9.

Department of Medicine, Division of Gastroenterology and Hepatology, Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

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February 2018

Reply.

Gastroenterology 2017 06 5;152(8):2083-2084. Epub 2017 May 5.

Department of Pediatrics and Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia.

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June 2017

Colonic ulcerations may predict steroid-refractory course in patients with ipilimumab-mediated enterocolitis.

World J Gastroenterol 2017 Mar;23(11):2023-2028

Animesh Jain, Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC 27599-7080, United States.

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March 2017

Genetic Risk for Inflammatory Bowel Disease Is a Determinant of Crohn's Disease Development in Chronic Granulomatous Disease.

Inflamm Bowel Dis 2016 12;22(12):2794-2801

*Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland; †Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, Maryland; ‡Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland; §Department of Medicine, Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland; ¶Laboratory of Clinical Infectious Diseases (LCID), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, Maryland; and **Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland.

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December 2016

Genetic Predictors of Benign Course of Ulcerative Colitis-A North American Inflammatory Bowel Disease Genetics Consortium Study.

Inflamm Bowel Dis 2016 10;22(10):2311-6

*Division of Gastroenterology, McGill University Health Center, Montreal, Quebec, Canada; †Montreal Heart Institute, Montreal, Quebec, Canada; ‡Université de Montréal, Montreal, Quebec, Canada; §Division of Gastroenterology, Mount Sinai Hospital, Toronto, Ontario, Canada; ‖Division of Gastroenterology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; ¶Section of Digestive Diseases, Yale University, New Haven, Connecticut; **Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; ††Division of Gastroenterology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York; ‡‡Translational Genomics Group, F. Widjaja Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; §§Division of Gastroenterology, University of Chicago, Chicago, Illinois; and ‖‖Meyerhoff Inflammatory Bowel Diseases Center, Division of Gastroenterology, Johns Hopkins School of Medicine, Baltimore, Maryland.

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October 2016

A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis.

Nat Commun 2016 08 9;7:12342. Epub 2016 Aug 9.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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August 2016

Whole-exome Sequence Analysis Implicates Rare Il17REL Variants in Familial and Sporadic Inflammatory Bowel Disease.

Inflamm Bowel Dis 2016 Jan;22(1):20-7

*Department of Pediatrics and †Center for Research Informatics, The University of Chicago, Chicago, Illinois; ‡Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom; §Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; ‖Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland; ¶F. Widjaja Family Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California; **Department of Genetics and Genomic Sciences and ††Zane Cohen Centre for Digestive Diseases, Department of Medicine, Mount Sinai Hospital, The University of Toronto, Toronto, Ontario, Canada; and ‡‡Department of Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York.

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January 2016

Prom1 function in development, intestinal inflammation, and intestinal tumorigenesis.

Front Oncol 2014 14;4:323. Epub 2014 Nov 14.

Department of Medicine, The Johns Hopkins University , Baltimore, MD , USA.

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December 2014

Promises, delivery, and challenges of inflammatory bowel disease risk gene discovery.

Authors:
Steven R Brant

Clin Gastroenterol Hepatol 2013 Jan 3;11(1):22-6. Epub 2012 Nov 3.

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, School of Medicine, Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21231, USA.

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January 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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November 2012

6-Mercaptopurine transport in human lymphocytes: correlation with drug-induced cytotoxicity.

J Dig Dis 2012 Feb;13(2):82-93

Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics Division of Gastroenterology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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February 2012

Novel candidate colorectal cancer biomarkers identified by methylation microarray-based scanning.

Endocr Relat Cancer 2011 Aug 4;18(4):465-78. Epub 2011 Jul 4.

Division of Gastroenterology, Department of Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, Maryland 21205, USA.

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August 2011

Recent insights into the genetics of inflammatory bowel disease.

Gastroenterology 2011 May;140(6):1704-12

Department of Medicine and Genetics, Yale University, New Haven, Connecticut, USA.

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May 2011

IL-23 receptor regulation by Let-7f in human CD4+ memory T cells.

J Immunol 2011 Jun 20;186(11):6182-90. Epub 2011 Apr 20.

Division of Gastroenterology, Department of Medicine, School of Medicine, Harvey M and Lyn P Meyerhoff Inflammatory Bowel Disease Center, The Johns Hopkins University, Baltimore, MD 21205, USA.

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June 2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

Authors:
Carl A Anderson Gabrielle Boucher Charlie W Lees Andre Franke Mauro D'Amato Kent D Taylor James C Lee Philippe Goyette Marcin Imielinski Anna Latiano Caroline Lagacé Regan Scott Leila Amininejad Suzannah Bumpstead Leonard Baidoo Robert N Baldassano Murray Barclay Theodore M Bayless Stephan Brand Carsten Büning Jean-Frédéric Colombel Lee A Denson Martine De Vos Marla Dubinsky Cathryn Edwards David Ellinghaus Rudolf S N Fehrmann James A B Floyd Timothy Florin Denis Franchimont Lude Franke Michel Georges Jürgen Glas Nicole L Glazer Stephen L Guthery Talin Haritunians Nicholas K Hayward Jean-Pierre Hugot Gilles Jobin Debby Laukens Ian Lawrance Marc Lémann Arie Levine Cecile Libioulle Edouard Louis Dermot P McGovern Monica Milla Grant W Montgomery Katherine I Morley Craig Mowat Aylwin Ng William Newman Roel A Ophoff Laura Papi Orazio Palmieri Laurent Peyrin-Biroulet Julián Panés Anne Phillips Natalie J Prescott Deborah D Proctor Rebecca Roberts Richard Russell Paul Rutgeerts Jeremy Sanderson Miquel Sans Philip Schumm Frank Seibold Yashoda Sharma Lisa A Simms Mark Seielstad A Hillary Steinhart Stephan R Targan Leonard H van den Berg Morten Vatn Hein Verspaget Thomas Walters Cisca Wijmenga David C Wilson Harm-Jan Westra Ramnik J Xavier Zhen Z Zhao Cyriel Y Ponsioen Vibeke Andersen Leif Torkvist Maria Gazouli Nicholas P Anagnou Tom H Karlsen Limas Kupcinskas Jurgita Sventoraityte John C Mansfield Subra Kugathasan Mark S Silverberg Jonas Halfvarson Jerome I Rotter Christopher G Mathew Anne M Griffiths Richard Gearry Tariq Ahmad Steven R Brant Mathias Chamaillard Jack Satsangi Judy H Cho Stefan Schreiber Mark J Daly Jeffrey C Barrett Miles Parkes Vito Annese Hakon Hakonarson Graham Radford-Smith Richard H Duerr Séverine Vermeire Rinse K Weersma John D Rioux

Nat Genet 2011 Mar 6;43(3):246-52. Epub 2011 Feb 6.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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March 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

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December 2010

Identification of microRNAs associated with ileal and colonic Crohn's disease.

Inflamm Bowel Dis 2010 Oct;16(10):1729-38

Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, Illinois 60637, USA.

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October 2010

Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease.

Inflamm Bowel Dis 2011 Jan 1;17(1):241-50. Epub 2010 Sep 1.

Department of Medicine, Section of Gastroenterology, University of Chicago, Chicago, Illinois 60637, USA.

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January 2011

Racial disparities in utilization of specialist care and medications in inflammatory bowel disease.

Am J Gastroenterol 2010 Oct 18;105(10):2202-8. Epub 2010 May 18.

Mount Sinai Hospital IBD Centre, University of Toronto, Ontario, Canada.

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October 2010

Common variants at five new loci associated with early-onset inflammatory bowel disease.

Authors:
Marcin Imielinski Robert N Baldassano Anne Griffiths Richard K Russell Vito Annese Marla Dubinsky Subra Kugathasan Jonathan P Bradfield Thomas D Walters Patrick Sleiman Cecilia E Kim Aleixo Muise Kai Wang Joseph T Glessner Shehzad Saeed Haitao Zhang Edward C Frackelton Cuiping Hou James H Flory George Otieno Rosetta M Chiavacci Robert Grundmeier Massimo Castro Anna Latiano Bruno Dallapiccola Joanne Stempak Debra J Abrams Kent Taylor Dermot McGovern Gary Silber Iwona Wrobel Antonio Quiros Jeffrey C Barrett Sarah Hansoul Dan L Nicolae Judy H Cho Richard H Duerr John D Rioux Steven R Brant Mark S Silverberg Kent D Taylor M Michael Barmuda Alain Bitton Themistocles Dassopoulos Lisa Wu Datta Todd Green Anne M Griffiths Emily O Kistner Michael T Murtha Miguel D Regueiro Jerome I Rotter L Philip Schumm A Hillary Steinhart Stephen R Targan Ramnik J Xavier Cécile Libioulle Cynthia Sandor Mark Lathrop Jacques Belaiche Olivier Dewit Ivo Gut Simon Heath Debby Laukens Myriam Mni Paul Rutgeerts André Van Gossum Diana Zelenika Denis Franchimont J P Hugot Martine de Vos Severine Vermeire Edouard Louis Lon R Cardon Carl A Anderson Hazel Drummond Elaine Nimmo Tariq Ahmad Natalie J Prescott Clive M Onnie Sheila A Fisher Jonathan Marchini Jilur Ghori Suzannah Bumpstead Rhian Gwillam Mark Tremelling Panos Delukas John Mansfield Derek Jewell Jack Satsangi Christopher G Mathew Miles Parkes Michel Georges Mark J Daly Melvin B Heyman George D Ferry Barbara Kirschner Jessica Lee Jonah Essers Richard Grand Michael Stephens Arie Levine David Piccoli John Van Limbergen Salvatore Cucchiara Dimitri S Monos Stephen L Guthery Lee Denson David C Wilson Straun F A Grant Mark Daly Mark S Silverberg Jack Satsangi Hakon Hakonarson

Nat Genet 2009 Dec 15;41(12):1335-40. Epub 2009 Nov 15.

Center for Applied Genomics, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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December 2009

NOD2 mutations and anti-Saccharomyces cerevisiae antibodies are risk factors for Crohn's disease in African Americans.

Am J Gastroenterol 2010 Feb 13;105(2):378-86. Epub 2009 Oct 13.

Gastroenterology Division, Department of Medicine, The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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February 2010

Racial and geographic disparities in the use of parenteral nutrition among inflammatory bowel disease inpatients diagnosed with malnutrition in the United States.

JPEN J Parenter Enteral Nutr 2009 Sep-Oct;33(5):563-8. Epub 2009 Jun 29.

Mount Sinai Hospital IBD Centre, University of Toronto, Toronto, Ontario, Canada.

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October 2009

Patient trust-in-physician and race are predictors of adherence to medical management in inflammatory bowel disease.

Inflamm Bowel Dis 2009 Aug;15(8):1233-9

Mount Sinai Hospital IBD Centre, University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.

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August 2009

MicroRNAs are differentially expressed in ulcerative colitis and alter expression of macrophage inflammatory peptide-2 alpha.

Gastroenterology 2008 Nov 3;135(5):1624-1635.e24. Epub 2008 Aug 3.

The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Division of Gastroenterology, The Johns Hopkins University Medical Institutions, Baltimore, Maryland 21205-2195, USA.

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November 2008

Is there a gender difference in the prevalence of Crohn's disease or ulcerative colitis?

Inflamm Bowel Dis 2008 Oct;14 Suppl 2:S2-3

Meyeroff Inflamatory Bowel Disease Center, Department of Medicine, School of Medicine, Department of Epidemiology, Blamberg School of Public Health, Johns Hopkins University, Maryland, USA.

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October 2008

Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn's disease risk in a population-based case-control study: evidence of gene-gene interactions.

Inflamm Bowel Dis 2008 Nov;14(11):1528-41

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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November 2008

A national survey of the prevalence and impact of Clostridium difficile infection among hospitalized inflammatory bowel disease patients.

Am J Gastroenterol 2008 Jun 29;103(6):1443-50. Epub 2008 May 29.

Mount Sinai Hospital IBD Centre, University of Toronto School of Medicine, Toronto, Ontario, Canada.

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June 2008

SNP analysis using CataCleave probes.

J Clin Lab Anal 2008 ;22(3):192-203

Excimus Biotech, Inc., 8510 Corridor Road, Savage, MD 20763, USA.

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July 2008

Rising hospitalization rates for inflammatory bowel disease in the United States between 1998 and 2004.

Inflamm Bowel Dis 2007 Dec;13(12):1529-35

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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December 2007

Community-based health preferences for proctocolectomy: a race comparison.

Dig Dis Sci 2008 Mar 1;53(3):741-6. Epub 2007 Sep 1.

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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March 2008

NFKB1 promoter variation implicates shear-induced NOS3 gene expression and endothelial function in prehypertensives and stage I hypertensives.

Am J Physiol Heart Circ Physiol 2007 Oct 20;293(4):H2320-7. Epub 2007 Jul 20.

Department of Kinesiology, College of Health Professions, Temple University, Philadelphia, Pennsylvania 19122, USA.

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October 2007

Race and health insurance are predictors of hospitalized Crohn's disease patients undergoing bowel resection.

Inflamm Bowel Dis 2007 Nov;13(11):1408-16

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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November 2007

Analysis of keratin polypeptides 8 and 19 variants in inflammatory bowel disease.

Clin Gastroenterol Hepatol 2007 Jul 16;5(7):857-64. Epub 2007 May 16.

Department of Medicine, Palo Alto Veterans Affairs Medical Center and Stanford University Digestive Disease Center, Palo Alto, California 94304, USA.

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July 2007

Testing the interaction between NOD-2 status and serological response to Mycobacterium paratuberculosis in cases of inflammatory bowel disease.

J Clin Microbiol 2007 Mar 24;45(3):968-71. Epub 2007 Jan 24.

Department of Internal Medicine, University of Manitoba Inflammatory Bowel Disease Clinical and Research Centre, Winnipeg, Manitoba, Canada.

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March 2007

Antibodies to saccharomyces cerevisiae in Crohn's disease: higher titers are associated with a greater frequency of mutant NOD2/CARD15 alleles and with a higher probability of complicated disease.

Inflamm Bowel Dis 2007 Feb;13(2):143-51

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Gastroenterology Division, Department of Medicine, Johns Hopkins University School of Medicine, 600 North Wolfe St., Blalock 463, Baltimore, MD 21287, USA.

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February 2007

Racial and geographic variations in colectomy rates among hospitalized ulcerative colitis patients.

Clin Gastroenterol Hepatol 2006 Dec;4(12):1507-1513

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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December 2006

A population-based case-control study of CARD15 and other risk factors in Crohn's disease and ulcerative colitis.

Am J Gastroenterol 2007 Feb 13;102(2):313-23. Epub 2006 Nov 13.

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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February 2007

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.

Science 2006 Dec 26;314(5804):1461-3. Epub 2006 Oct 26.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, University of Pittsburgh Medical Center Presbyterian, Mezzanine Level, C-Wing, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

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December 2006

Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease.

Am J Physiol Gastrointest Liver Physiol 2006 Jun 26;290(6):G1157-63. Epub 2006 Jan 26.

Department of Pathology and Laboratory Medicine, Epithelial Pathobiology Unit, Emory University School of Medicine, Atlanta, GA 30322, USA.

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June 2006

NOD2, not yet: con.

Inflamm Bowel Dis 2005 May;11(5):507-9

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

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May 2005

A case of chronic intestinal ischemia presenting as chronic diarrhea without abdominal pain.

Dig Dis Sci 2005 Jan;50(1):18-23

Division of Gastroenterology, Johns Hopkins University, Baltimore, Maryland 21287, USA.

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January 2005

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Sep;10(5):513-20

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.

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September 2004

Inflammatory bowel disease gene hunting by linkage analysis: rationale, methodology, and present status of the field.

Inflamm Bowel Dis 2004 May;10(3):300-11

Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Gastroenterology Division, Department of Medicine, Johns Hopkins University School of Medicine. Baltimore, Maryland, USA.

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May 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Jan;10(1):15-22

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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January 2004