Steven M Lipkin

Steven M Lipkin

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Steven M Lipkin

Steven M Lipkin

Publications by authors named "Steven M Lipkin"

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68Publications

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Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.

Leukemia 2019 Sep 9;33(9):2324-2330. Epub 2019 Apr 9.

ProfilExpert, Lyon, France.

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http://dx.doi.org/10.1038/s41375-019-0452-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756025PMC
September 2019

Author Correction: Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.

Sci Rep 2019 Sep 30;9(1):13992. Epub 2019 Sep 30.

Nancy E. and Peter C. Meinig School of Biomedical Engineering, Cornell University, Ithaca, 14853, USA.

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http://dx.doi.org/10.1038/s41598-019-43805-3DOI Listing
September 2019

Immune Activation in Mismatch Repair Deficient Carcinogenesis: More Than Just Mutational Rate.

Clin Cancer Res 2019 Aug 5. Epub 2019 Aug 5.

Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0856DOI Listing
August 2019

Have Cells Harboring the HIV Reservoir Been Immunoedited?

Front Immunol 2019 6;10:1842. Epub 2019 Aug 6.

Department of Medicine, Weill Cornell Medical College, New York, NY, United States.

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http://dx.doi.org/10.3389/fimmu.2019.01842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691121PMC
August 2019

Proteomic characterization of outer membrane vesicles from gut mucosa-derived fusobacterium nucleatum.

J Proteomics 2019 Mar 8;195:125-137. Epub 2019 Jan 8.

Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18743919183045
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http://dx.doi.org/10.1016/j.jprot.2018.12.029DOI Listing
March 2019

NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.

Cancer Res 2016 06 11;76(11):3411-21. Epub 2016 Apr 11.

Department of Biomedical Engineering, Cornell University, Ithaca, New York. School of Electrical and Computer Engineering, Cornell University, Ithaca, New York. Department of Biomedical Engineering, Duke University, Durham, North Carolina.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-3198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891252PMC
June 2016

A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.

Elife 2016 04 14;5. Epub 2016 Apr 14.

Department of Biological and Environmental Engineering, Cornell University, Ithaca, United States.

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http://dx.doi.org/10.7554/eLife.14620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859802PMC
April 2016

A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.

Cell Stem Cell 2016 Feb;18(2):189-202

School of Electrical and Computer Engineering, Cornell University, Ithaca, NY 14853, USA; Department of Biomedical Engineering, Cornell University, Ithaca, NY 14853, USA; Department of Biological and Environmental Engineering, Cornell University, Ithaca, NY 14853, USA; Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4751059PMC
February 2016

miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.

Nat Commun 2015 Apr 15;6:6879. Epub 2015 Apr 15.

1] School of Electrical and Computer Engineering, Cornell University, Ithaca, New York 14853, USA [2] Department of Biomedical Engineering, Cornell University, Ithaca, New York 14853, USA [3] Department of Biological and Environmental Engineering, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1038/ncomms7879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399006PMC
April 2015

A massively parallel pipeline to clone DNA variants and examine molecular phenotypes of human disease mutations.

PLoS Genet 2014 Dec 11;10(12):e1004819. Epub 2014 Dec 11.

Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, New York, United States of America; Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America.

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http://files.figshare.com/1839935/Text_S1.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004819
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http://dx.doi.org/10.1371/journal.pgen.1004819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263371PMC
December 2014

Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.

Cancer Discov 2013 Sep 14;3(9):1072-81. Epub 2013 Jun 14.

1Departments of Medicine, Genetic Medicine and Cell Biology, and 2Pharmacology, Weill Cornell College of Medicine, New York, New York; and 3Division of Chemoprevention, National Cancer Institute, Frederick, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770777PMC
September 2013

Dissecting disease inheritance modes in a three-dimensional protein network challenges the "guilt-by-association" principle.

Am J Hum Genet 2013 Jul 20;93(1):78-89. Epub 2013 Jun 20.

Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1016/j.ajhg.2013.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710751PMC
July 2013

miR-23a promotes the transition from indolent to invasive colorectal cancer.

Cancer Discov 2012 Jun 30;2(6):540-53. Epub 2012 Mar 30.

Departments of Medicine, Genetic Medicine, Surgery, Pathology and Physiology and Biophysics, Weill Cornell Medical College, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651884PMC
June 2012

Three-dimensional reconstruction of protein networks provides insight into human genetic disease.

Nat Biotechnol 2012 Jan 15;30(2):159-64. Epub 2012 Jan 15.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1038/nbt.2106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708476PMC
January 2012

Frequency domain analysis reveals external periodic fluctuations can generate sustained p53 oscillation.

PLoS One 2011 28;6(7):e22852. Epub 2011 Jul 28.

Electrical and Computer Engineering, Cornell University, Ithaca, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022852PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145758PMC
December 2011

Clinical genetics of hereditary colorectal cancer.

Hematol Oncol Clin North Am 2010 Oct;24(5):837-59

Clinical Genetics, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.hoc.2010.06.006DOI Listing
October 2010

Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.

Cancer Prev Res (Phila) 2010 May 19;3(5):597-603. Epub 2010 Apr 19.

Department of Medicine, Weill Cornell School of Medicine, New York, New York 10021, USA.

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http://dx.doi.org/10.1158/1940-6207.CAPR-10-0007DOI Listing
May 2010

Survival of distinct Asian groups among colorectal cancer cases in California.

Cancer 2009 Jan;115(2):259-70

Division of Hematology/Oncology, Chao Family Comprehensive Cancer Center, University of California at Irvine, Irvine, California, USA.

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http://dx.doi.org/10.1002/cncr.24034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042844PMC
January 2009

A population-based, descriptive analysis of malignant intraductal papillary mucinous neoplasms of the pancreas.

Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2737-41

Chao Family Comprehensive Cancer Center, Division of Hematology/Oncology, School of Medicine, University of California, Irvine, CA 92697, USA.

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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http://dx.doi.org/10.1158/1055-9965.EPI-08-0417DOI Listing
October 2008

Effects of socioeconomic status and treatment disparities in colorectal cancer survival.

Cancer Epidemiol Biomarkers Prev 2008 Aug;17(8):1950-62

Chao Family Comprehensive Cancer Center, Division of Hematology/Oncology, School of Medicine, University of California at Irvine, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-2774DOI Listing
August 2008

Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice.

Dev Dyn 2008 Feb;237(2):316-27

Department of Medicine, University of California, Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1002/dvdy.21418DOI Listing
February 2008

Familial colorectal cancer syndrome X.

Semin Oncol 2007 Oct;34(5):425-7

Cancer Genetics Clinic, Chao Family NCI Designated Comprehensive Cancer Center, University of California, Irvine, CA 92697-4038, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2007.07.008DOI Listing
October 2007

Genetic testing to identify high-risk populations for chemoprevention studies.

Cancer Biomark 2007 ;3(3):163-8

Department of Medicine, Division of Hematology-Oncology, University of California, Irvine, CA 92697, USA.

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September 2007

Race, socioeconomic status, treatment, and survival time among pancreatic cancer cases in California.

Cancer Epidemiol Biomarkers Prev 2007 Mar;16(3):546-52

Chao Family Comprehensive Cancer Center, Division of Hematology/Oncology, University of California, Irvine Medical Center, 101 The City Drive South, Orange, CA 92868, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0893DOI Listing
March 2007

Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis.

Nucleic Acids Res 2006 6;34(3):840-52. Epub 2006 Feb 6.

Department of Medicine, Division of Hematology-Oncology, University of California Irvine, CA 92697-4038, USA.

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http://dx.doi.org/10.1093/nar/gkj489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361617PMC
February 2006

Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair.

Cancer Res 2005 Dec;65(23):10759-66

Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-2528DOI Listing
December 2005

Kinetics of cancer: a method to test hypotheses of genetic causation.

BMC Cancer 2005 Dec 21;5:163. Epub 2005 Dec 21.

Department of Ecology and Evolutionary Biology, University of California, Irvine, CA 92697-2525, USA.

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http://dx.doi.org/10.1186/1471-2407-5-163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1352380PMC
December 2005

What are SNPs and haplotypes and how will they help us manage the prevention of adult cancer?

Curr Oncol Rep 2005 Nov;7(6):475-9

Department of Medicine, Division of Hematology-Oncology, University of California, Irvine, 839 Medical Sciences Court, 2nd Floor, Sprague Hall--Lab 250, Irvine, CA 92697, USA.

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November 2005

Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.

Cancer Res 2005 Oct;65(19):8662-70

Department of Medicine and Biological Chemistry, University of California, Irvine, California, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-05-0742DOI Listing
October 2005

CDX2 polymorphisms, RNA expression, and risk of colorectal cancer.

Cancer Res 2005 Jul;65(13):5488-92

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0638, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-3645DOI Listing
July 2005

The MLH1 D132H variant is associated with susceptibility to sporadic colorectal cancer.

Nat Genet 2004 Jul 6;36(7):694-9. Epub 2004 Jun 6.

Division of Oncology, Department of Medicine, University of California, Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1038/ng1374DOI Listing
July 2004

Identification and characterization of Grainyhead-like epithelial transactivator (GET-1), a novel mammalian Grainyhead-like factor.

Dev Dyn 2003 Apr;226(4):604-17

Department of Medicine, Divisions of Endocrinology and Metabolism, University of California, Irvine, California 92697, USA.

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http://dx.doi.org/10.1002/dvdy.10255DOI Listing
April 2003

Meiotic arrest and aneuploidy in MLH3-deficient mice.

Nat Genet 2002 Aug 1;31(4):385-90. Epub 2002 Jul 1.

Division of Hematology-Oncology, Department of Medicine, University of California, Irvine, California 92697, USA.

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http://www.nature.com/articles/ng931
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http://dx.doi.org/10.1038/ng931DOI Listing
August 2002

Family with acute myelocytic leukemia, breast, ovarian, and gastrointestinal cancer.

Cancer Genet Cytogenet 2002 Aug;137(1):8-14

Department of Preventive Medicine and Public Health, Creighton University School of Medicine, 2500 California Plaza, Omaha, NE 68178, USA.

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http://dx.doi.org/10.1016/s0165-4608(02)00537-xDOI Listing
August 2002