Steven M Larson

Steven M Larson

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Steven M Larson

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Do You Want an Inspirational Career? Choose Nuclear Medicine.

Authors:
Steven M Larson

J Nucl Med 2019 Sep;60(Suppl 2):25S-28S

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http://dx.doi.org/10.2967/jnumed.118.220574DOI Listing
September 2019

Copper-64 trastuzumab PET imaging: a reproducibility study.

Q J Nucl Med Mol Imaging 2019 Jun 12;63(2):191-198. Epub 2016 May 12.

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.23736/S1824-4785.16.02867-3DOI Listing
June 2019

Measuring the unmeasurable: automated bone scan index as a quantitative endpoint in prostate cancer clinical trials.

Prostate Cancer Prostatic Dis 2019 Apr 29. Epub 2019 Apr 29.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://www.nature.com/articles/s41391-019-0151-4
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http://dx.doi.org/10.1038/s41391-019-0151-4DOI Listing
April 2019

Harnessing Androgen Receptor Pathway Activation for Targeted Alpha Particle Radioimmunotherapy of Breast Cancer.

Clin Cancer Res 2019 01 25;25(2):881-891. Epub 2018 Sep 25.

Division of Oncology and Pathology, and Medical Radiation Physics, Department of Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524527PMC
January 2019

Antibody with Infinite Affinity for In Vivo Tracking of Genetically Engineered Lymphocytes.

J Nucl Med 2018 12 14;59(12):1894-1900. Epub 2018 Jun 14.

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.2967/jnumed.118.208041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278895PMC
December 2018

Convection-enhanced delivery for diffuse intrinsic pontine glioma: a single-centre, dose-escalation, phase 1 trial.

Lancet Oncol 2018 08 18;19(8):1040-1050. Epub 2018 Jun 18.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pediatrics, Weill Medical College of Cornell University, New York, USA.

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http://dx.doi.org/10.1016/S1470-2045(18)30322-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692905PMC
August 2018

TMSOTf assisted synthesis of 2'-deoxy-2'-[18F]fluoro-β-D-arabinofuranosylcytosine ([18F]FAC).

PLoS One 2018 1;13(5):e0196784. Epub 2018 May 1.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196784PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5929562PMC
July 2018

Theranostic Concepts: More Than Just a Fashion Trend-Introduction and Overview.

J Nucl Med 2017 09;58(Suppl 2):1S-2S

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.2967/jnumed.117.199570DOI Listing
September 2017

Quantitative Assessment of Early [F]Sodium Fluoride Positron Emission Tomography/Computed Tomography Response to Treatment in Men With Metastatic Prostate Cancer to Bone.

J Clin Oncol 2017 Aug 27;35(24):2829-2837. Epub 2017 Jun 27.

Stephanie A. Harmon, Timothy Perk, Christie Lin, Jens Eickhoff, Glenn Liu, and Robert Jeraj, University of Wisconsin-Madison; Glenn Liu and Robert Jeraj, Prostate Cancer Clinical Trials Consortium, Madison, WI; Peter L. Choyke, William L. Dahut, and Andrea B. Apolo, National Cancer Institute, Bethesda, MD; John L. Humm, Steven M. Larson, and Michael J. Morris, Memorial Sloan Kettering Cancer Center; and Steven M. Larson and Michael J. Morris, Prostate Cancer Clinical Trials Consortium, New York, NY.

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http://dx.doi.org/10.1200/JCO.2017.72.2348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562173PMC
August 2017

Redifferentiating Thyroid Cancer: Selumetinib-enhanced Radioiodine Uptake in Thyroid Cancer.

Mol Imaging Radionucl Ther 2017 02;26(Suppl 1):80-86

Memorial Sloan Kettering Cancer Center, New York, USA, Phone: 646888359, E-mail:

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http://dx.doi.org/10.4274/2017.26.suppl.09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283711PMC
February 2017

Copper-64 labeled liposomes for imaging bone marrow.

Nucl Med Biol 2016 Dec 27;43(12):781-787. Epub 2016 Aug 27.

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Radiology, Weill Cornell Medical College, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2016.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118102PMC
December 2016

Corrigendum to "Molecular imaging for personalized cancer care" [Mol. Oncol. 6(2) (2012) 182-195].

Mol Oncol 2016 12 2;10(10):1627. Epub 2016 Oct 2.

Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Room C-278, NY 10065, USA.

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http://dx.doi.org/10.1016/j.molonc.2016.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423130PMC
December 2016

Evaluation of Castration-Resistant Prostate Cancer with Androgen Receptor-Axis Imaging.

J Nucl Med 2016 Oct;57(Suppl 3):73S-78S

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and

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http://dx.doi.org/10.2967/jnumed.115.170134DOI Listing
October 2016

Arsenic Trioxide as a Radiation Sensitizer for 131I-Metaiodobenzylguanidine Therapy: Results of a Phase II Study.

J Nucl Med 2016 Feb 7;57(2):231-7. Epub 2016 Jan 7.

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.2967/jnumed.115.161752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976822PMC
February 2016

EXINI Quantitative Bone Scan Index: Expanded Utility for the Planar Radionuclide Bone Scan.

Authors:
Steven M Larson

J Nucl Med 2016 Jan 8;57(1):5-6. Epub 2015 Oct 8.

Memorial Sloan Kettering Cancer Center, New York, New York

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http://dx.doi.org/10.2967/jnumed.115.164137DOI Listing
January 2016

Non-invasive mapping of deep-tissue lymph nodes in live animals using a multimodal PET/MRI nanoparticle.

Nat Commun 2014 ;5:3097

1] Department of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), 1275 York Street, Box 248, New York, New York 10065, USA [2] Program in Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Center (MSKCC), 1275 York Street, Box 248, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncomms4097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080716PMC
October 2015

Radioimmunotherapy of human tumours.

Nat Rev Cancer 2015 Jun;15(6):347-60

1] Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, P.O. BOX 19024, Seattle, Washington 98109, USA. [2].

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http://dx.doi.org/10.1038/nrc3925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4798425PMC
June 2015

Indium 111-labeled J591 anti-PSMA antibody for vascular targeted imaging in progressive solid tumors.

EJNMMI Res 2015 29;5:28. Epub 2015 Apr 29.

Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065 USA ; Department of Medicine, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065 USA.

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http://dx.doi.org/10.1186/s13550-015-0104-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425739PMC
May 2015

Prostate cancer: Better use of bone scans in prostate cancer.

Authors:
Steven M Larson

Nat Rev Urol 2015 Apr 11;12(4):190-1. Epub 2014 Nov 11.

Molecular Imaging and Therapy Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/nrurol.2014.305DOI Listing
April 2015

Radiolabeled antibodies in prostate cancer: a case study showing the effect of host immunity on antibody bio-distribution.

Nucl Med Biol 2015 Apr 23;42(4):375-80. Epub 2014 Dec 23.

Department of Surgery (Urology), Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Department of Clinical Sciences, Division of Urological Research, Lund University, Malmö, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nucmedbio.2014.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472383PMC
April 2015

Radiographic progression-free survival as a response biomarker in metastatic castration-resistant prostate cancer: COU-AA-302 results.

J Clin Oncol 2015 Apr 26;33(12):1356-63. Epub 2015 Jan 26.

Michael J. Morris, Steven M. Larson, and Howard I. Scher, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY; Arturo Molina, Thian Kheoh, Shannon L. Matheny, Vahid Naini, and Thomas W. Griffin, Janssen Research & Development, Los Angeles; Eric J. Small and Charles J. Ryan, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA; Johann S. de Bono, Institute for Cancer Research and Royal Marsden Hospital, Sutton, United Kingdom; Christopher J. Logothetis, MD Anderson Cancer Center, Houston, TX; Karim Fizazi, Institut Gustave Roussy, University of Paris Sud, Villejuif, France; Paul de Souza, University of Western Sydney School of Medicine, Ingham Institute, Liverpool, New South Wales, Australia; Philip W. Kantoff, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; Celestia S. Higano, University of Washington, Seattle, WA; Jinhui Li, Janssen Research & Development, Raritan, NJ; and Tomasz Burzykowski, International Drug Development Institute, Louvain-la-Neuve, Belgium.

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http://dx.doi.org/10.1200/JCO.2014.55.3875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881370PMC
April 2015

Preclinical evaluation of multistep targeting of diasialoganglioside GD2 using an IgG-scFv bispecific antibody with high affinity for GD2 and DOTA metal complex.

Mol Cancer Ther 2014 Jul 18;13(7):1803-12. Epub 2014 Jun 18.

Pediatrics; Program in Molecular Pharmacology and Chemistry, Memorial Sloan Kettering Cancer Center, New York, New York

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221074PMC
July 2014

Bone metastases in castration-resistant prostate cancer: associations between morphologic CT patterns, glycolytic activity, and androgen receptor expression on PET and overall survival.

Radiology 2014 Apr 18;271(1):220-9. Epub 2013 Nov 18.

From the Department of Radiology (H.A.V., C.W., J.J.F., A.W., D.A.G., S.M.L., H.H.), Department of Epidemiology and Biostatistics (D.K., M.G.), and Genitourinary Oncology Service, Department of Medicine (M.J.M., H.I.S.), Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10065; and Department of Radiology, Oncology and Radiations Sciences, Section of Radiology, Nuclear Medicine and PET, Uppsala University, Uppsala, Sweden (C.W.).

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http://dx.doi.org/10.1148/radiol.13130625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4263648PMC
April 2014

How to assess background activity: introducing a histogram-based analysis as a first step for accurate one-step PET quantification.

Nucl Med Commun 2014 Mar;35(3):316-24

Departments of aRadiology bMedical Physics cEpidemiology-Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, USA dDepartment of Radiology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1097/MNM.0000000000000045DOI Listing
March 2014

Evaluation of glycodendron and synthetically modified dextran clearing agents for multistep targeting of radioisotopes for molecular imaging and radioimmunotherapy.

Mol Pharm 2014 Feb 23;11(2):400-16. Epub 2013 Nov 23.

Department of Radiology, ‡Organic Synthesis Core Facility, §Program in Molecular Pharmacology and Chemistry, and ∥Molecular Pharmacology and Therapy Service, Memorial Sloan-Kettering Cancer Center , New York, New York 10065, United States.

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http://dx.doi.org/10.1021/mp4003128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270281PMC
February 2014

Bone-seeking radiopharmaceuticals for treatment of osseous metastases, Part 1: α therapy with 223Ra-dichloride.

J Nucl Med 2014 Feb 16;55(2):268-74. Epub 2013 Dec 16.

Molecular Imaging and Therapy Service, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.2967/jnumed.112.112482DOI Listing
February 2014

Pilot study of 68Ga-DOTA-F(ab')2-trastuzumab in patients with breast cancer.

Nucl Med Commun 2013 Dec;34(12):1157-65

aDepartment of Radiology, Molecular Imaging and Therapy Service bDepartment of Medicine, Breast Cancer Medicine Service cHuman Oncology and Pathogenesis Program dDepartment of Medical Physics eRadiochemistry and Molecular Imaging Probes Core Facility, Memorial Sloan-Kettering Cancer Center Departments of fRadiology gMedicine, Weill Cornell Medical College, New York, New York, USA.

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http://dx.doi.org/10.1097/MNM.0b013e328365d99bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815146PMC
December 2013

N-acetylgalactosamino dendrons as clearing agents to enhance liver targeting of model antibody-fusion protein.

Bioconjug Chem 2013 Dec 18;24(12):2088-103. Epub 2013 Nov 18.

Organic Synthesis Core Facility, ‡Molecular Pharmacology and Chemistry Program, §Department of Radiology, and ∥Molecular Pharmacology and Therapy Service, Memorial Sloan-Kettering Cancer Center , New York, New York, United States.

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http://dx.doi.org/10.1021/bc400333mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900322PMC
December 2013

Phase I study of ARN-509, a novel antiandrogen, in the treatment of castration-resistant prostate cancer.

J Clin Oncol 2013 Oct 3;31(28):3525-30. Epub 2013 Sep 3.

Dana E. Rathkopf, Michael J. Morris, Josef J. Fox, Daniel C. Danila, Susan F. Slovin, Mithat Gönen, Martin Fleisher, Steven M. Larson, Charles L. Sawyers, and Howard I. Scher, Memorial Sloan-Kettering Cancer Center; Dana E. Rathkopf, Michael J. Morris, Josef J. Fox, Daniel C. Danila, Susan F. Slovin, Steven M. Larson, and Howard I. Scher, Weill Cornell Medical College, New York, NY; Jeffrey H. Hager, Peter J. Rix, Edna Chow Maneval, and Isan Chen, Aragon Pharmaceuticals, San Diego, CA; and Charles L. Sawyers, Howard Hughes Medical Institute, Chevy Chase, MD.

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http://dx.doi.org/10.1200/JCO.2013.50.1684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782148PMC
October 2013

Repetitively dosed docetaxel and ¹⁵³samarium-EDTMP as an antitumor strategy for metastatic castration-resistant prostate cancer.

Cancer 2013 Sep 13;119(17):3186-94. Epub 2013 Jun 13.

Genitourinary Oncology Service, Sidney Kimmel Center for Prostate and Urologic Cancers, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1002/cncr.28103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775970PMC
September 2013

Imaging of tumor vascularization using fluorescence molecular tomography to monitor arginine deiminase treatment in melanoma.

Mol Imaging 2013 Jan-Feb;12(1):67-73

Department of Nuclear Medicine, Human Oncology and Pathogenesis Program, and Ludwig Institute for Cancer Research, New York Branch, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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July 2013

Molecular imaging of prostate cancer.

Curr Opin Urol 2012 Jul;22(4):320-7

Molecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOU.0b013e32835483d5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373349PMC
July 2012

Computer-aided quantitative bone scan assessment of prostate cancer treatment response.

Nucl Med Commun 2012 Apr;33(4):384-94

Department of Radiological Sciences, Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90024, USA.

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http://dx.doi.org/10.1097/MNM.0b013e3283503ebfDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294499PMC
April 2012

Bone marrow dosimetry using 124I-PET.

J Nucl Med 2012 Apr 13;53(4):615-21. Epub 2012 Mar 13.

Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.2967/jnumed.111.096453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390781PMC
April 2012

Molecular imaging for personalized cancer care.

Mol Oncol 2012 Apr 10;6(2):182-95. Epub 2012 Mar 10.

Department of Radiology, Memorial Sloan-Kettering Cancer Center, NY 10065, USA.

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http://dx.doi.org/10.1016/j.molonc.2012.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528375PMC
April 2012

Imaging androgen receptor signaling with a radiotracer targeting free prostate-specific antigen.

Cancer Discov 2012 Apr 31;2(4):320-7. Epub 2012 Mar 31.

Department of Surgery, Howard Hughes Medical Institute, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351274PMC
April 2012

Novel mechanistic insights into arginine deiminase pharmacology suggest 18F-FDG is not suitable to evaluate clinical response in melanoma.

J Nucl Med 2012 Feb 6;53(2):281-6. Epub 2012 Jan 6.

Nuclear Medicine Service, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.2967/jnumed.111.092973DOI Listing
February 2012

The Janus project: the remaking of nuclear medicine and radiology.

Authors:
Steven M Larson

J Nucl Med 2011 Dec;52 Suppl 2:3S-9S

Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.2967/jnumed.110.085761DOI Listing
December 2011

Oncology.

Authors:
Steven M Larson

J Nucl Med 2011 Nov;52(11):13N-20N

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November 2011