Steven M Hill

Steven M Hill

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Steven M Hill

Steven M Hill

Publications by authors named "Steven M Hill"

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Epigenetic inhibition of the tumor suppressor ARHI by light at night-induced circadian melatonin disruption mediates STAT3-driven paclitaxel resistance in breast cancer.

J Pineal Res 2019 Sep 9;67(2):e12586. Epub 2019 Jun 9.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana.

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http://dx.doi.org/10.1111/jpi.12586DOI Listing
September 2019

Circadian Health and Light: A Report on the National Heart, Lung, and Blood Institute's Workshop.

J Biol Rhythms 2018 10 23;33(5):451-457. Epub 2018 Jul 23.

Center for Circadian and Sleep Medicine, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1177/0748730418789506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414068PMC
October 2018

Effects of Colored Enrichment Devices on Circadian Metabolism and Physiology in Male Sprague-Dawley Rats.

Comp Med 2016 ;66(5):384-391

Division of Veterinary Medicine, Tulane National Primate Research Center, Covington, Louisiana, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073063PMC
December 2017

Effect of Isoflurane Anesthesia on Circadian Metabolism and Physiology in Rats.

Comp Med 2017 Mar;67(2):138-146

Division of Veterinary Medicine, Tulane National Primate Research Center, Covington, Louisiana.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402733PMC
March 2017

Melatonin Represses Metastasis in Her2-Postive Human Breast Cancer Cells by Suppressing RSK2 Expression.

Mol Cancer Res 2016 11 17;14(11):1159-1169. Epub 2016 Aug 17.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107120PMC
November 2016

DREAMTools: a Python package for scoring collaborative challenges.

F1000Res 2015 9;4:1030. Epub 2015 Oct 9.

European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI),Wellcome Trust Genome Campus, Cambridge, UK; RWTH Aachen University Medical Hospital, Joint Research Centre for Computational Biomedicine (JRCCOMBINE), Aachen, Germany.

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http://dx.doi.org/10.12688/f1000research.7118.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837986PMC
May 2016

Melatonin suppression of aerobic glycolysis (Warburg effect), survival signalling and metastasis in human leiomyosarcoma.

J Pineal Res 2016 Mar 23;60(2):167-77. Epub 2015 Dec 23.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA.

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http://dx.doi.org/10.1111/jpi.12298DOI Listing
March 2016

Doxorubicin resistance in breast cancer is driven by light at night-induced disruption of the circadian melatonin signal.

J Pineal Res 2015 Aug 20;59(1):60-9. Epub 2015 Apr 20.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA.

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http://dx.doi.org/10.1111/jpi.12239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490975PMC
August 2015

Melatonin: an inhibitor of breast cancer.

Endocr Relat Cancer 2015 Jun 15;22(3):R183-204. Epub 2015 Apr 15.

Department of Structural and Cellular BiologyTulane University School of Medicine, 1430 Tulane Avenue, SL-49, New Orleans, Louisiana 70112, USADepartment of SurgeryTulane Cancer Center and Louisiana Cancer Research ConsortiumCircadian Cancer Biology GroupTulane Center for Circadian BiologyTulane University School of Medicine, New Orleans, Louisiana 70112, USA Department of Structural and Cellular BiologyTulane University School of Medicine, 1430 Tulane Avenue, SL-49, New Orleans, Louisiana 70112, USADepartment of SurgeryTulane Cancer Center and Louisiana Cancer Research ConsortiumCircadian Cancer Biology GroupTulane Center for Circadian BiologyTulane University School of Medicine, New Orleans, Louisiana 70112, USA Department of Structural and Cellular BiologyTulane University School of Medicine, 1430 Tulane Avenue, SL-49, New Orleans, Louisiana 70112, USADepartment of SurgeryTulane Cancer Center and Louisiana Cancer Research ConsortiumCircadian Cancer Biology GroupTulane Center for Circadian BiologyTulane University School of Medicine, New Orleans, Louisiana 70112, USA Department of Structural and Cellular BiologyTulane University School of Medicine, 1430 Tulane Avenue, SL-49, New Orleans, Louisiana 70112, USADepartment of SurgeryTulane Cancer Center and Louisiana Cancer Research ConsortiumCircadian Cancer Biology GroupTulane Center for Circadian BiologyTulane University School of Medicine, New Orleans, Louisiana 70112, USA.

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http://erc.endocrinology-journals.org/content/22/3/R183.full
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http://erc.endocrinology-journals.org/cgi/doi/10.1530/ERC-15
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http://dx.doi.org/10.1530/ERC-15-0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457700PMC
June 2015

The aging clock and circadian control of metabolism and genome stability.

Front Genet 2014 14;5:455. Epub 2015 Jan 14.

Tulane Cancer Center, Tulane Center for Aging, and Tulane Center for Circadian Biology New Orleans, LA, USA ; Department of Medicine, Tulane University New Orleans, LA, USA.

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http://dx.doi.org/10.3389/fgene.2014.00455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294216PMC
February 2015

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night.

Nucleic Acids Res 2014 Jul 9;42(12):7694-707. Epub 2014 Jun 9.

Department of Structural and Cellular Biology, Tulane School of Medicine, Tulane Cancer Center, New Orleans, LA 70115, USA Tulane Center for Aging, New Orleans, LA 70112, USA

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http://dx.doi.org/10.1093/nar/gku503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081101PMC
July 2014

Molecular deficiency (ies) in MT₁ melatonin signaling pathway underlies the melatonin-unresponsive phenotype in MDA-MB-231 human breast cancer cells.

J Pineal Res 2014 Apr 18;56(3):246-53. Epub 2014 Jan 18.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA, USA; Tulane Cancer Center and Louisiana Cancer Research Consortium, New Orleans, LA, USA.

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http://dx.doi.org/10.1111/jpi.12117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868402PMC
April 2014

Age-related decline in melatonin and its MT1 receptor are associated with decreased sensitivity to melatonin and enhanced mammary tumor growth.

Curr Aging Sci 2013 Feb;6(1):125-33

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana, USA.

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February 2013

Bayesian inference of signaling network topology in a cancer cell line.

Bioinformatics 2012 Nov 24;28(21):2804-10. Epub 2012 Aug 24.

Department of Biochemistry, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/bioinformatics/bts514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476330PMC
November 2012

Circadian gating of epithelial-to-mesenchymal transition in breast cancer cells via melatonin-regulation of GSK3β.

Mol Endocrinol 2012 Nov 21;26(11):1808-20. Epub 2012 Sep 21.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA.

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http://dx.doi.org/10.1210/me.2012-1071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487627PMC
November 2012

Methylseleninic acid enhances paclitaxel efficacy for the treatment of triple-negative breast cancer.

PLoS One 2012 14;7(2):e31539. Epub 2012 Feb 14.

Departments of Structural and Cellular Biology, Tulane Cancer Center, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0031539PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279411PMC
July 2012

A new apparatus and surgical technique for the dual perfusion of human tumor xenografts in situ in nude rats.

Comp Med 2012 Apr;62(2):99-108

Department of Structural and Cellular Biology, Tulane University School of Medicine, Tulane, Louisiana, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3318246PMC
April 2012

Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway.

Breast Cancer Res 2010 17;12(6):R107. Epub 2010 Dec 17.

Department of Structural and Cellular Biology, Tulane University School of Medicine, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1186/bcr2794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046452PMC
September 2011

Melatonin and associated signaling pathways that control normal breast epithelium and breast cancer.

J Mammary Gland Biol Neoplasia 2011 Sep 20;16(3):235-45. Epub 2011 Jul 20.

Department of Structural and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Avenue, SL-49, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1007/s10911-011-9222-4DOI Listing
September 2011

Phosphorylation of Estrogen Receptor α at serine 118 directs recruitment of promoter complexes and gene-specific transcription.

Endocrinology 2011 Jun 19;152(6):2517-26. Epub 2011 Apr 19.

Tulane University School of Medicine, Department of Structural and Cellular Biology, 1430 Tulane Avenue SL-49, New Orleans, Louisiana 70112.

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http://dx.doi.org/10.1210/en.2010-1281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100622PMC
June 2011

Declining melatonin levels and MT1 receptor expression in aging rats is associated with enhanced mammary tumor growth and decreased sensitivity to melatonin.

Breast Cancer Res Treat 2011 May 12;127(1):91-8. Epub 2010 Jun 12.

Department of Structural and Cellular Biology, Tulane University School of Medicine, 1430 Tulane Ave, SL-49, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1007/s10549-010-0958-0DOI Listing
May 2011

Network clustering: probing biological heterogeneity by sparse graphical models.

Bioinformatics 2011 Apr 10;27(7):994-1000. Epub 2011 Feb 10.

Department of Statistics, University of Warwick, Coventry, UK.

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http://dx.doi.org/10.1093/bioinformatics/btr070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065697PMC
April 2011

Melatonin inhibits mitogenic cross-talk between retinoic acid-related orphan receptor alpha (RORalpha) and ERalpha in MCF-7 human breast cancer cells.

Steroids 2010 Dec 15;75(12):944-51. Epub 2010 Jun 15.

Department of Structural and Cellular Biology, Tulane Cancer Center and Tulane University Health Sciences Center, 1430 Tulane Ave., SL-49, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1016/j.steroids.2010.06.002DOI Listing
December 2010

In vitro and in vivo antitumor activity of melatonin receptor agonists.

J Pineal Res 2010 Oct 1;49(3):210-21. Epub 2010 Jul 1.

Department of Structural & Cellular Biology, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1111/j.1600-079X.2010.00781.xDOI Listing
October 2010

Molecular mechanisms of melatonin anticancer effects.

Integr Cancer Ther 2009 Dec;8(4):337-46

Tulane University, 1430 Tulane Avenue, SL-49, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1177/1534735409353332DOI Listing
December 2009

Period-2: a tumor suppressor gene in breast cancer.

J Circadian Rhythms 2008 Mar 11;6. Epub 2008 Mar 11.

Department of Structural and Cellular Biology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1186/1740-3391-6-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2365929PMC
March 2008

Tracking the elusive antiestrogenic effect of melatonin: a new methodological approach.

Neuro Endocrinol Lett 2003 Dec;24(6):440-4

Dept. of Gynecology and Obstetrics, University of Ulm, Prittwitzstrasse 43, D-89075 Ulm, Germany.

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December 2003

MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.

Mol Cell Endocrinol 2002 Jun;192(1-2):147-56

Department of Structural and Cellular Biology, Tulane University Medical School, 1430 Tulane Avenue, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1016/s0303-7207(02)00029-1DOI Listing
June 2002

Modulation of intracellular calcium and calmodulin by melatonin in MCF-7 human breast cancer cells.

J Pineal Res 2002 Mar;32(2):112-9

Department of Structural and Cellular Biology, Tulane University Cancer Center, Tulane University School of Medicine, New Orleans, LA 70112, USA.

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March 2002