Publications by authors named "Steven L Reiner"

86Publications

Transient T-bet expression functionally specifies a distinct T follicular helper subset.

J Exp Med 2018 11 19;215(11):2705-2714. Epub 2018 Sep 19.

Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1084/jem.20180927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219743PMC
November 2018

TCF1 expression marks self-renewing human CD8 T cells.

Blood Adv 2018 07;2(14):1685-1690

Department of Microbiology and Immunology and.

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http://dx.doi.org/10.1182/bloodadvances.2018016279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058237PMC
July 2018

Clonal Bifurcation of Foxp3 Expression Visualized in Thymocytes and T Cells.

Immunohorizons 2018 Apr 9;2(4):119-128. Epub 2018 Apr 9.

Department of Microbiology and Immunology, College of Physicians and Surgeons of Columbia University, New York, NY 10032.

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http://dx.doi.org/10.4049/immunohorizons.1700064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922779PMC
April 2018

Metabolic control of cell fate bifurcations in a hematopoietic progenitor population.

Immunol Cell Biol 2018 09 6;96(8):863-871. Epub 2018 Apr 6.

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.

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http://dx.doi.org/10.1111/imcb.12040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146018PMC
September 2018

Cutting Edge: Divergent Requirement of T-Box Transcription Factors in Effector and Memory NK Cells.

J Immunol 2018 03 9;200(6):1977-1981. Epub 2018 Feb 9.

Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065;

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http://dx.doi.org/10.4049/jimmunol.1700416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840019PMC
March 2018

Securing front-line T cell defense.

Authors:
Steven L Reiner

Immunol Cell Biol 2018 03 10;96(3):241-242. Epub 2018 Feb 10.

Department of Microbiology and Immunology, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.

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http://dx.doi.org/10.1111/imcb.12013DOI Listing
March 2018

Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway.

Cell Rep 2018 01 28;22(4):860-868. Epub 2018 Jan 28.

Department of Microbiology and Immunology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.12.087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806629PMC
January 2018

IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination.

Immunohorizons 2017 Sep;1(7):156-161

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.

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http://dx.doi.org/10.4049/immunohorizons.1700012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608100PMC
September 2017

Lymphocyte Fate and Metabolism: A Clonal Balancing Act.

Trends Cell Biol 2017 12 14;27(12):946-954. Epub 2017 Aug 14.

Department of Microbiology and Immunology, and Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2017.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696055PMC
December 2017

Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.

Cell Rep 2016 12;17(12):3142-3152

Department of Microbiology and Immunology and Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.11.065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189677PMC
December 2016

CD8 T Lymphocyte Self-Renewal during Effector Cell Determination.

Cell Rep 2016 11;17(7):1773-1782

Department of Microbiology and Immunology and Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.10.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108530PMC
November 2016

Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection.

J Immunol 2016 08 18;197(4):1017-22. Epub 2016 Jul 18.

Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104;

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http://dx.doi.org/10.4049/jimmunol.1500368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975981PMC
August 2016

Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.

J Exp Med 2016 Mar 22;213(3):415-31. Epub 2016 Feb 22.

Department of Pathology, New York University Langone Medical Center, New York, NY 10016 Department of Medicine, New York University Langone Medical Center, New York, NY 10016 Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032

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http://dx.doi.org/10.1084/jem.20150642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813676PMC
March 2016

Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage.

J Immunol 2016 Feb 20;196(4):1449-54. Epub 2016 Jan 20.

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032; Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032;

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http://dx.doi.org/10.4049/jimmunol.1502396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744497PMC
February 2016

Asymmetric PI3K Signaling Driving Developmental and Regenerative Cell Fate Bifurcation.

Cell Rep 2015 Dec 25;13(10):2203-18. Epub 2015 Nov 25.

Department of Microbiology and Immunology and Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.10.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685001PMC
December 2015

T-bet transcendent: unmasking the faces of multifarious immunity.

Authors:
Steven L Reiner

J Immunol 2015 Apr;194(7):2959-60

Department of Microbiology and Immunology and Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032

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http://dx.doi.org/10.4049/jimmunol.1500289DOI Listing
April 2015

Lymphocyte fate specification as a deterministic but highly plastic process.

Nat Rev Immunol 2014 10 5;14(10):699-704. Epub 2014 Sep 5.

Department of Microbiology and Immunology, and the Department of Pediatrics at the College of Physicians and Surgeons, Columbia University, 701 West 168th Street, HHSC 912, New York, New York 10032, USA.

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http://dx.doi.org/10.1038/nri3734DOI Listing
October 2014

Cutting edge: CXCR4 is critical for CD8+ memory T cell homeostatic self-renewal but not rechallenge self-renewal.

J Immunol 2014 Aug 27;193(3):1013-6. Epub 2014 Jun 27.

Department of Microbiology and Immunology, College of Physicians and Surgeons, Columbia University, New York, NY 10032; Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032;

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http://dx.doi.org/10.4049/jimmunol.1400488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108510PMC
August 2014

The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.

Proc Natl Acad Sci U S A 2013 Mar 19;110(10):4081-6. Epub 2013 Feb 19.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.

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http://dx.doi.org/10.1073/pnas.1209076110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593833PMC
March 2013

Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.

Science 2012 Nov;338(6111):1220-5

Department of Microbiology and Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1229620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653769PMC
November 2012

Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes.

J Leukoc Biol 2013 Feb 27;93(2):307-15. Epub 2012 Nov 27.

Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1189/jlb.0812400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545675PMC
February 2013

Divergent transcriptional programming of class-specific B cell memory by T-bet and RORα.

Nat Immunol 2012 May 6;13(6):604-11. Epub 2012 May 6.

Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA.

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http://www.nature.com/articles/ni.2294
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http://dx.doi.org/10.1038/ni.2294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3362691PMC
May 2012

Cutting edge: Asymmetric memory T cell division in response to rechallenge.

J Immunol 2012 May 30;188(9):4145-8. Epub 2012 Mar 30.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1200176
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http://dx.doi.org/10.4049/jimmunol.1200176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331961PMC
May 2012

Asymmetric B cell division in the germinal center reaction.

Science 2012 Jan 15;335(6066):342-4. Epub 2011 Dec 15.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1213495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282111PMC
January 2012

Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

J Immunol 2010 Dec 12;185(12):7151-5. Epub 2010 Nov 12.

Abramson Family Cancer Research Institute, Division of Infectious Diseases, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1003193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997140PMC
December 2010

Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.

J Immunol 2010 Nov 8;185(9):4988-92. Epub 2010 Oct 8.

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.1002042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975552PMC
November 2010

Micro-RNA-155 inhibits IFN-gamma signaling in CD4+ T cells.

Eur J Immunol 2010 Jan;40(1):225-31

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/eji.200939381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807623PMC
January 2010

The precursors of memory: models and controversies.

Nat Rev Immunol 2009 09 14;9(9):662-8. Epub 2009 Aug 14.

Emory Vaccine Center, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1038/nri2619DOI Listing
September 2009

A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection.

Immunity 2009 Aug 6;31(2):309-20. Epub 2009 Aug 6.

Immunology Program and Wistar Vaccine Center, The Wistar Institute, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.immuni.2009.06.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2747257PMC
August 2009

Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation.

J Immunol 2009 Apr;182(8):4686-95

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.4049/jimmunol.0803180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922395PMC
April 2009

CD152 (CTLA-4) regulates effector functions of CD8+ T lymphocytes by repressing Eomesodermin.

Eur J Immunol 2009 Mar;39(3):883-93

Department of Pediatrics, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

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http://doi.wiley.com/10.1002/eji.200838770
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http://dx.doi.org/10.1002/eji.200838770DOI Listing
March 2009

Decision making during the conception and career of CD4+ T cells.

Authors:
Steven L Reiner

Nat Rev Immunol 2009 Feb;9(2):81-2

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http://dx.doi.org/10.1038/nri2490DOI Listing
February 2009

Helping and harming have something in common.

Nat Immunol 2009 Feb;10(2):138-40

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http://dx.doi.org/10.1038/ni0209-138DOI Listing
February 2009

Inducing the T cell fates required for immunity.

Authors:
Steven L Reiner

Immunol Res 2008 ;42(1-3):160-5

Abramson Family Cancer Research Institute and Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, 421 Curie Blvd., Room 414, Philadelphia, PA, 19104-6160, USA.

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http://dx.doi.org/10.1007/s12026-008-8054-9DOI Listing
March 2009

Specifying helper T cell fates during immunity.

J Pediatr Gastroenterol Nutr 2008 Apr;46 Suppl 1:E19-20

University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1097/01.mpg.0000313832.47207.0eDOI Listing
April 2008

Two-photon imaging of effector T-cell behavior: lessons from a tumor model.

Immunol Rev 2008 Feb;221:147-62

The Wistar Institute, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/j.1600-065X.2008.00596.xDOI Listing
February 2008

Protection one cell thick.

Immunity 2007 Dec;27(6):832-4

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.immuni.2007.11.009DOI Listing
December 2007

Antagonistic nature of T helper 1/2 developmental programs in opposing peripheral induction of Foxp3+ regulatory T cells.

Proc Natl Acad Sci U S A 2007 Nov 31;104(46):18169-74. Epub 2007 Oct 31.

Department of Immunology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1073/pnas.0703642104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084315PMC
November 2007

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells.

J Exp Med 2007 Sep 13;204(9):2015-21. Epub 2007 Aug 13.

Abramson Family Cancer Research Institute, Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1084/jem.20070841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118697PMC
September 2007

Activation of retinoic acid receptor-alpha favours regulatory T cell induction at the expense of IL-17-secreting T helper cell differentiation.

Eur J Immunol 2007 Sep;37(9):2396-9

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1002/eji.200737621DOI Listing
September 2007

Division of labor with a workforce of one: challenges in specifying effector and memory T cell fate.

Science 2007 Aug;317(5838):622-5

Abramson Family Cancer Research Institute of the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1143775DOI Listing
August 2007

Development in motion: helper T cells at work.

Authors:
Steven L Reiner

Cell 2007 Apr;129(1):33-6

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009286740700382
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http://dx.doi.org/10.1016/j.cell.2007.03.019DOI Listing
April 2007

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

Science 2007 Mar 1;315(5819):1687-91. Epub 2007 Mar 1.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1126/science.1139393DOI Listing
March 2007

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells.

J Immunol 2007 Mar;178(5):2730-6

Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.4049/jimmunol.178.5.2730DOI Listing
March 2007

Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation.

J Exp Med 2007 Feb 12;204(2):267-72. Epub 2007 Feb 12.

Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1084/jem.20061982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118724PMC
February 2007

Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.

J Immunol 2006 Dec;177(11):7515-9

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA.

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http://www.jimmunol.org/content/177/11/7515.full.pdf
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http://dx.doi.org/10.4049/jimmunol.177.11.7515DOI Listing
December 2006

IL-21 inhibits IFN-gamma production in developing Th1 cells through the repression of Eomesodermin expression.

J Immunol 2006 Sep;177(6):3721-7

Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.177.6.3721DOI Listing
September 2006

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

Immunity 2006 Jul;25(1):79-91

Department of Pathology, University of Massachusetts Medical School, Worcester, 01655, USA.

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http://dx.doi.org/10.1016/j.immuni.2006.05.012DOI Listing
July 2006

Not-so-great expectations: re-assessing the essence of T-cell memory.

Immunol Rev 2006 Jun;211:203-13

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2006.00396.xDOI Listing
June 2006

Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major.

J Immunol 2006 Jul;177(2):925-33

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696341PMC
http://dx.doi.org/10.4049/jimmunol.177.2.925DOI Listing
July 2006

T-bet down-modulation in tolerized Th1 effector CD4 cells confers a TCR-distal signaling defect that selectively impairs IFN-gamma expression.

J Immunol 2006 Jan;176(2):1036-45

Center for Immunotherapy of Cancer and Infectious Diseases and Department of Immunology, University of Connecticut Health Center, Farmington, CT 06030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846362PMC
http://dx.doi.org/10.4049/jimmunol.176.2.1036DOI Listing
January 2006

Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.

Nat Immunol 2005 Dec 6;6(12):1236-44. Epub 2005 Nov 6.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1038/ni1268DOI Listing
December 2005

Transcriptional activators of helper T cell fate are required for establishment but not maintenance of signature cytokine expression.

J Immunol 2005 Nov;175(9):5981-5

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.175.9.5981DOI Listing
November 2005

Cutting edge: a critical role for gene silencing in preventing excessive type 1 immunity.

J Immunol 2005 Nov;175(9):5606-10

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.175.9.5606DOI Listing
November 2005

Epigenetic control in the immune response.

Authors:
Steven L Reiner

Hum Mol Genet 2005 Apr;14 Spec No 1:R41-6

Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/hmg/ddi115DOI Listing
April 2005

Sliding doors in the immune response.

Nat Immunol 2005 Jan;6(1):10-2

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http://dx.doi.org/10.1038/ni0105-10DOI Listing
January 2005

Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.

Eur J Immunol 2004 Dec;34(12):3604-13

Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/eji.200425469DOI Listing
December 2004

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules.

J Immunol 2004 Sep;173(6):3773-82

Centre d'Immunologie de Marseille-Luminy, Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de la Méditerranée, Campus de Luminy, Marseille, France.

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http://dx.doi.org/10.4049/jimmunol.173.6.3773DOI Listing
September 2004

Cutting Edge: Innate production of IFN-gamma by NK cells is independent of epigenetic modification of the IFN-gamma promoter.

J Immunol 2004 Aug;173(3):1514-7

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.173.3.1514DOI Listing
August 2004

STAT1 plays a critical role in the regulation of antimicrobial effector mechanisms, but not in the development of Th1-type responses during toxoplasmosis.

J Immunol 2004 Jan;172(1):457-63

Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 3800 Spruce Street, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.4049/jimmunol.172.1.457DOI Listing
January 2004

Immunity and the animation of the genome.

Authors:
Steven L Reiner

Immunity 2003 Dec;19(6):775-80

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/s1074-7613(03)00333-9DOI Listing
December 2003

Helper T cell differentiation and the problem of cellular inheritance.

Immunol Res 2003 ;27(2-3):463-8

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1385/IR:27:2-3:463DOI Listing
March 2004

The lineage decisions of helper T cells.

Nat Rev Immunol 2002 Dec;2(12):933-44

Howard Hughes Medical Institute and Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

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http://www.nature.com/articles/nri954
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http://dx.doi.org/10.1038/nri954DOI Listing
December 2002

Gene silencing quantitatively controls the function of a developmental trans-activator.

Mol Cell 2002 Jul;10(1):81-91

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia 19104, USA.

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http://dx.doi.org/10.1016/s1097-2765(02)00564-6DOI Listing
July 2002

Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction.

Nat Immunol 2002 Jul 10;3(7):652-8. Epub 2002 Jun 10.

Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1038/ni807DOI Listing
July 2002